Processing of β-Secretase by Furin and Other Members of the Proprotein Convertase Family

Journal of Biological Chemistry

Volumn 276, Issue 6, 2001, Pages 4211-4217

  Creemers, John W M ^a   Dominguez, Diana Ines ^a   Plets, Evelyn ^a   Serneels, Lutgarde ^a   Taylor, Neil A ^a   Multhaup, Gerd ^b   Craessaerts, Katleen ^a   Annaert, Wim ^a   De Strooper, Bart ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOSYNTHESIS; BRAIN; DISEASES;

AMYLOID PEPTIDES;

ENZYMES;

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; FURIN; ASPARTIC PROTEINASE; SUBTILISIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL LEVEL; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; ENZYME ACTIVITY; IMMUNOFLUORESCENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; ENZYMOLOGY; HIPPOCAMPUS; HUMAN; METABOLISM;

ANIMALIA;

AMYLOID BETA-PROTEIN PRECURSOR; ASPARTIC ENDOPEPTIDASES; FURIN; HIPPOCAMPUS; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBTILISINS;

EID: 0035830897     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006947200     Document Type: Article

References (37)

1. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
2. Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., and Beyreuther, K. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4245-4249
3. Haass, C., and Selkoe, D. J. (1993) Cell 75, 1039-1042
4. De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., and Van Leuven, F. (1998) Nature 391, 387-390
5. Esler, W. P., Kimberly, W. T., Ostaszewski, B. L., Diehl, T. S., Moore, C. L., Tsai, J. Y., Rahmati, T., Xia, W., Selkoe, D. J., and Wolfe, M. S. (2000) Nat. Cell. Biol. 2, 428-434
6. Wolfe, M. S., Xia, W., Ostaszewski, B. L., Diehl, T. S., Kimberly, W. T., and Selkoe, D. J. (1999) Nature 398, 513-517
7. Li, Y. M., Xu, M., Lai, M. T., Huang, Q., Castro, J. L., DiMuzio-Mower, J., Harrison, T., Lellis, C., Nadin, A., Neduvelil, J. G., Register, R. B., Sardana, M. K., Shearman, M. S., Smith, A. L., Shi, X. P., Yin, K. C., Shafer, J. A., and Gardell, S. J. (2000) Nature 405, 689-694
8. Hussain, I., Powell, D., Howlett, D. R., Tew, D. G., Meek, T. D., Chapman, C., Gloger, I. S., Murphy, K. E., Southan, C. D., Ryan, D. M., Smith, T. S., Simmons, D. L., Walsh, F. S., Dingwall, C., and Christie, G. (1999) Mol. Cell. Neurosci. 14, 419-427
9. Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G., and Citron, M. (1999) Science 286, 735-741
10. Sinha, S., Anderson, J. P., Barbour, R., Basi, G. S., Caccavello, R., Davis, D., Doan, M., Dovey, H. F., Frigon, N., Hong, J., Jacobson-Croak, K., Jewett, N., Keim, P., Knops, J., Lieberburg, I., Power, M., Tan, H., Tatsuno, G., Tung, J., Schenk, D., Seubert, P., Suomensaari, S. M., Wang, S., Walker, D., Zhao, J., McConologue, L., and John, V. (1999) Nature 402, 537-540
11. Yan, R., Bienkowski, M. J., Shuck, M. E., Miao, H., Tory, M. C., Pauley, A. M., Brashier, J. R., Stratman, N. C., Mathews, W. R., Buhl, A. E., Carter, D. B., Tomasselli, A. G., Parodi, L. A., Heinrikson, R. L., and Gurney, M. E. (1999) Nature 402, 533-537
12. Lin, X., Koelsch, G., Wu, S., Downs, D., Dashti, A., and Tang, J. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1456-1460
13. Seidah, N. G., and Chretien, M. (1999) Brain Res. 848, 45-62
14. Haniu, M., Denis, P., Young, Y., Mendiaz, E. A., Fuller, J., Hui, J. O., Bennett, B. D., Kahn, S., Ross, S., Burgess, T., Katta, V., Rogers, G., Vassar, R., and Citron, M. (2000) J. Biol. Chem. 275, 21099-21106
15. Capell, A., Steiner, H., Willem, M., Kaiser, H., Meyer, C., Walter, J., Lammich, S., Multhaup, G., and Haass, C. (2000) J. Biol. Chem. 275, 30849-30854
16. Steiner, D. F. (1998) Curr. Opin. Chem. Biol. 2, 31-39
17. Nakayama, K. (1997) Biochem. J. 327, 625-635
18. Kim, S. H., Wang, R., Gordon, D. J., Bass, J., Steiner, D. F., Lynn, D. G., Thinakaran, G., Meredith, S. C., and Sisodia, S. S. (1999) Nat. Neurosci. 2, 984-988
19. Vidal, R., Frangione, B., Rostagno, A., Mead, S., Revesz, T., Plant, G., and Ghiso, J. (1999) Nature 399, 776-781
20. Thinakaran, G., Teplow, D. B., Siman, R., Greenberg, B., and Sisodia, S. S. (1996) J. Biol. Chem. 271, 9390-9397
21. Spence, M. J., Sucic, J. F., Foley, B. T., and Moehring, T. J. (1995) Somatic Cell Mol. Genet. 21, 1-18
22. Creemers, J. W., Vey, M., Schafer, W., Ayoubi, T. A., Roebroek, A. J., Klenk, H. D., Garten, W., and Van de Ven, W. J. (1995) J. Biol. Chem. 270, 2695-2702
23. van de Loo, J. W., Creemers, J. W., Bright, N. A., Young, B. D., Roebroek, A. J., and Van de Ven, W. J. (1997) J. Biol. Chem. 272, 27116-27123
24. De Strooper, B., Craessaerts, K., Van Leuven, F., and Van Den Berghe, H. (1995) J. Biol. Chem. 270, 30310-30314
25. Ploegh, H. L. (1995) in Current Protocols in Protein Science (Coligan, J. E., Dunn, B. M., Ploegh, H. L., Speicher, D. W., and Wingfield, P. T., eds) pp. 10.2.1-10.2.8, John Wiley & Sons, Inc., New York
26. Jean, F., Stella, K., Thomas, L., Liu, G., Xiang, Y., Reason, A. J., and Thomas, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7293-7298
27. Benjannet, S., Savaria, D., Laslop, A., Munzer, J. S., Chretien, M., Marcinkewicz, M., and Seidah, N. G. (1997) J. Biol. Chem. 272, 26210-26218
28. Simons, M., de Strooper, B., Multhaup, G., Tienari, P. J., Dotti, C. G., and Beyreuther, K. (1996) J. Neurosci. 16, 899-908
29. Hung, A. Y., Haass, C., Nitsch, R. M., Qiu, W. Q., Citron, M., Wurtman, R. J., Growdon, J. H., and Selkoe, D. J. (1993) J. Biol. Chem. 268, 22959-22962
30. Savage, M. J., Trusko, S. P., Howland, D. S., Pinsker, L. R., Mistretta, S., Reaume, A. G., Greenberg, B. D., Siman, R., and Scott, R. W. (1998) J. Neurosci. 18, 1743-1752
31. Buxbaum, J. D., Koo, E. H., and Greengard, P. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9195-9198
32. Hartmann, T., Bieger, S. C., Bruhl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K., and Beyreuther, K. (1997) Nat. Med. 3, 1016-1020
33. Tienari, P. J., Ida, N., Ikonen, E., Simons, M., Weidemann, A., Multhaup, G., Masters, C. L., Dotti, C. G., and Beyreuther, K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4125-4130
34. Wild-Bode, C., Yamazaki, T., Capell, A., Leimer, U., Steiner, H., Ihara, Y., and Haass, C. (1997) J. Biol. Chem. 272, 16085-16088
35. Chyung, A. S. C., Greenberg, B. D., Cook, D. G., Doms, R. W., and Lee, V. M. (1997) J. Cell Biol. 138, 671-680
36. Annaert, W. G., Levesque, L., Craessaerts, K., Dierinck, I., Snellings, G., Westaway, D., St. George-Hyslop, P., Cordell, B., Fraser, P., and De Strooper, B. (1999) J. Cell Biol. 147, 277-294
37. Benett, B., Denis, P., Haniu, M., Teplow, D. B., Kahn, S., Louis J. C., Citron, M. and Vassar, R. (2000) J. Biol. Chem. 275, 37712-37717