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Volumn 275, Issue 48, 2000, Pages 37712-37717

A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's β-secretase

(8) Bennett, Brian D a Denis, Paul a Haniu, Mitsuru a Teplow, David B b Kahn, Steve a Louis, Jean Claude a Citron, Martin a Vassar, Robert a

a AMGEN INC (United States)

b MASSACHUSETTS GENERAL HOSPITAL (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; BREFELDIN A; CALPAIN; FURIN; IONOPHORE; MONENSIN; PEPTIDE DERIVATIVE; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CANCER CELL CULTURE; CATALYSIS; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME SYNTHESIS; GENETIC TRANSFECTION; GOLGI COMPLEX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; CATALYSIS; CELL LINE; DNA PRIMERS; ENDOPEPTIDASES; FURIN; GOLGI APPARATUS; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SUBTILISINS;

EID: 0034529080 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M005339200 Document Type: Article

Times cited : (243)

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