-
1
-
-
0031614624
-
Alzheimer disease
-
Smith MA: Alzheimer disease. Int Rev Neurobiol 1998;42:1-54.
-
(1998)
Int Rev Neurobiol
, vol.42
, pp. 1-54
-
-
Smith, M.A.1
-
2
-
-
0033537306
-
Signal transduction abnormalities in Alzheimer's disease: Evidence of a pathogenic stimuli
-
McShea A, Zelasko DA, Gerst JL, Smith MA: Signal transduction abnormalities in Alzheimer's disease: Evidence of a pathogenic stimuli. Brain Res 1999;815:237-242.
-
(1999)
Brain Res
, vol.815
, pp. 237-242
-
-
McShea, A.1
Zelasko, D.A.2
Gerst, J.L.3
Smith, M.A.4
-
3
-
-
0033516947
-
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
-
Perry G, Roder H, Nunomura A, et al: Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport 1999;10:2411-2415.
-
(1999)
Neuroreport
, vol.10
, pp. 2411-2415
-
-
Perry, G.1
Roder, H.2
Nunomura, A.3
-
4
-
-
0034781046
-
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
-
Zhu X, Rottkamp CA, Hartzler A, et al: Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. J Neurochem 2001;79:311-318.
-
(2001)
J Neurochem
, vol.79
, pp. 311-318
-
-
Zhu, X.1
Rottkamp, C.A.2
Hartzler, A.3
-
5
-
-
0027269660
-
Cortical pyramidal neuron loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: Investigative and therapeutic perspectives
-
Francis PT, Sims NR, Procter AW, Bowen DM: Cortical pyramidal neuron loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: Investigative and therapeutic perspectives. J Neurochem 1993;60:1589-1604.
-
(1993)
J Neurochem
, vol.60
, pp. 1589-1604
-
-
Francis, P.T.1
Sims, N.R.2
Procter, A.W.3
Bowen, D.M.4
-
6
-
-
0026584524
-
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
-
Beal MF: Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 1992;31:119-130.
-
(1992)
Ann Neurol
, vol.31
, pp. 119-130
-
-
Beal, M.F.1
-
7
-
-
0030769436
-
Glutamate toxicity enhances tau gene expression in neuronal cultures
-
Esclaire F, Lesort M, Blanchard C, Hugon J: Glutamate toxicity enhances tau gene expression in neuronal cultures. J Neurosci Res 1997;49:309-318.
-
(1997)
J Neurosci Res
, vol.49
, pp. 309-318
-
-
Esclaire, F.1
Lesort, M.2
Blanchard, C.3
Hugon, J.4
-
8
-
-
0029991888
-
Modifications of neuronal phosphorylated tau immunoreactivity induced by NMDA toxicity
-
Couratier P, Lesort M, Sindou P, Esclaire F, Yardin C, Hugon J: Modifications of neuronal phosphorylated tau immunoreactivity induced by NMDA toxicity. Mol Chem Neuropathol 1996;27:259-273.
-
(1996)
Mol Chem Neuropathol
, vol.27
, pp. 259-273
-
-
Couratier, P.1
Lesort, M.2
Sindou, P.3
Esclaire, F.4
Yardin, C.5
Hugon, J.6
-
9
-
-
0029015501
-
Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists
-
Couratier P, Sindou P, Tabaraud F, Diop AG, Spencer PS, Hugon J: Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists. Neurodegeneration 1995;4:33-41.
-
(1995)
Neurodegeneration
, vol.4
, pp. 33-41
-
-
Couratier, P.1
Sindou, P.2
Tabaraud, F.3
Diop, A.G.4
Spencer, P.S.5
Hugon, J.6
-
10
-
-
0037567850
-
Introduction to glutamate receptors, their function and pharmacology
-
Danysz W, Lodge D, Parsons CG (eds). Johnson City, F.P. Graham Publishing
-
Parsons C, Danysz W, Lodge D: Introduction to glutamate receptors, their function and pharmacology; in Danysz W, Lodge D, Parsons CG (eds): Ionotropic Glutamate Receptors as Therapeutic Targets. Johnson City, F.P. Graham Publishing, 2002, pp 1-30.
-
(2002)
Ionotropic Glutamate Receptors as Therapeutic Targets
, pp. 1-30
-
-
Parsons, C.1
Danysz, W.2
Lodge, D.3
-
11
-
-
0023125256
-
The physiology of excitatory amino acids in the vertebrate central nervous system
-
Mayer ML, Westbrook GL: The physiology of excitatory amino acids in the vertebrate central nervous system. Prog Neurobiol 1987;28:197-276.
-
(1987)
Prog Neurobiol
, vol.28
, pp. 197-276
-
-
Mayer, M.L.1
Westbrook, G.L.2
-
12
-
-
0024596865
-
The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
-
Monaghan DT, Bridges RJ, Cotman CW: The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu Rev Pharmacol Toxicol 1989;29:365-402.
-
(1989)
Annu Rev Pharmacol Toxicol
, vol.29
, pp. 365-402
-
-
Monaghan, D.T.1
Bridges, R.J.2
Cotman, C.W.3
-
13
-
-
0037067583
-
Requirement for hippocampal CA3 NMDA receptors in associative memory recall
-
Nakazawa K, Quirk MC, Chitwood RA, et al: Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science 2002;297:211-218.
-
(2002)
Science
, vol.297
, pp. 211-218
-
-
Nakazawa, K.1
Quirk, M.C.2
Chitwood, R.A.3
-
14
-
-
0036583275
-
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat
-
Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD: A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 2002;22:3628-3637.
-
(2002)
J Neurosci
, vol.22
, pp. 3628-3637
-
-
Clayton, D.A.1
Mesches, M.H.2
Alvarez, E.3
Bickford, P.C.4
Browning, M.D.5
-
15
-
-
0032053963
-
Facilitative effects of the ampakine CX516 on short-term memory in rats: Correlations with hippocampal neuronal activity
-
Hampson RE, Rogers G, Lynch G, Deadwyler SA: Facilitative effects of the ampakine CX516 on short-term memory in rats: Correlations with hippocampal neuronal activity. J Neurosci 1998;18:2748-2763.
-
(1998)
J Neurosci
, vol.18
, pp. 2748-2763
-
-
Hampson, R.E.1
Rogers, G.2
Lynch, G.3
Deadwyler, S.A.4
-
16
-
-
0032053403
-
Facilitative effects of the ampakine CX516 on short-term memory in rats: Enhancement of delayed-nonmatch-to-sample performance
-
Hampson RE, Rogers G, Lynch G, Deadwyler SA: Facilitative effects of the ampakine CX516 on short-term memory in rats: Enhancement of delayed-nonmatch-to- sample performance. J Neurosci 1998;18:2740-2747.
-
(1998)
J Neurosci
, vol.18
, pp. 2740-2747
-
-
Hampson, R.E.1
Rogers, G.2
Lynch, G.3
Deadwyler, S.A.4
-
17
-
-
0032122422
-
Memory and the brain: Unexpected chemistries and a new pharmacology
-
Lynch G: Memory and the Brain: Unexpected Chemistries and a New Pharmacology. Neurobiol Learn Mem 1998;70:82-100.
-
(1998)
Neurobiol Learn Mem
, vol.70
, pp. 82-100
-
-
Lynch, G.1
-
18
-
-
0033531214
-
The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn
-
Hayashi T, Umemori H, Mishina M, Yamamoto T: The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn. Nature 1999;397:72-76.
-
(1999)
Nature
, vol.397
, pp. 72-76
-
-
Hayashi, T.1
Umemori, H.2
Mishina, M.3
Yamamoto, T.4
-
19
-
-
0033994676
-
Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons
-
Lauterborn JC, Lynch G, Vanderklish P, Arai A, Gall CM: Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci 2000;20:8-21.
-
(2000)
J Neurosci
, vol.20
, pp. 8-21
-
-
Lauterborn, J.C.1
Lynch, G.2
Vanderklish, P.3
Arai, A.4
Gall, C.M.5
-
20
-
-
0036629919
-
An AMPA receptor potentiator modulates the expression of BDNF: An in vivo study
-
Mackowiak M, O'Neill MJ, Hicks CA, Bleakman D, Skolnick P: An AMPA receptor potentiator modulates the expression of BDNF: An in vivo study. Neuropharmacology 2002;43:1-10.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1-10
-
-
Mackowiak, M.1
O'Neill, M.J.2
Hicks, C.A.3
Bleakman, D.4
Skolnick, P.5
-
21
-
-
0025265926
-
The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
-
Choi DW, Rothman SM: The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990;13:171-182.
-
(1990)
Annu Rev Neurosci
, vol.13
, pp. 171-182
-
-
Choi, D.W.1
Rothman, S.M.2
-
22
-
-
0025063609
-
Excitatory amino acid neurotoxicity and neurodegenerative disease
-
Meldrum B, Garthwaite J: Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 1990;11:379-387.
-
(1990)
Trends Pharmacol Sci
, vol.11
, pp. 379-387
-
-
Meldrum, B.1
Garthwaite, J.2
-
23
-
-
0032967382
-
The role of excitotoxicity in neurodegenerative disease: Implications for therapy
-
Doble A: The role of excitotoxicity in neurodegenerative disease: Implications for therapy. Pharmacol Ther 1999;81:163-221.
-
(1999)
Pharmacol Ther
, vol.81
, pp. 163-221
-
-
Doble, A.1
-
24
-
-
0031912995
-
Glutamate receptors in the mammalian central nervous system
-
Ozawa S, Kamiya H, Tsuzuki K: Glutamate receptors in the mammalian central nervous system. Prog Neurobiol 1998;54:581-618.
-
(1998)
Prog Neurobiol
, vol.54
, pp. 581-618
-
-
Ozawa, S.1
Kamiya, H.2
Tsuzuki, K.3
-
25
-
-
0026497926
-
Excitotoxic cell death
-
Choi DW: Excitotoxic cell death. J Neurobiol 1992;23:1261-1276.
-
(1992)
J Neurobiol
, vol.23
, pp. 1261-1276
-
-
Choi, D.W.1
-
26
-
-
0023137252
-
Ionic dependence of glutamate neurotoxicity
-
Choi DW: Ionic dependence of glutamate neurotoxicity. J Neurosci 1987;7:369-379.
-
(1987)
J Neurosci
, vol.7
, pp. 369-379
-
-
Choi, D.W.1
-
28
-
-
0036179194
-
Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes
-
Lynch DR, Guttmann RP: Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes. J Pharmacol Exp Ther 2002; 300:717-723.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 717-723
-
-
Lynch, D.R.1
Guttmann, R.P.2
-
29
-
-
0026437728
-
Molecular diversity of glutamate receptors and implications for brain function
-
Nakanishi S: Molecular diversity of glutamate receptors and implications for brain function. Science 1992;258:597-603.
-
(1992)
Science
, vol.258
, pp. 597-603
-
-
Nakanishi, S.1
-
30
-
-
0028810883
-
Structure and function of the NMDA receptor channel
-
Mori H, Mishina M: Structure and function of the NMDA receptor channel. Neuropharmacology 1995;34:1219-1237.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1219-1237
-
-
Mori, H.1
Mishina, M.2
-
31
-
-
0022650213
-
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
-
Morris RG, Anderson E, Lynch GS, Baudry M: Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature 1986;319:774-776.
-
(1986)
Nature
, vol.319
, pp. 774-776
-
-
Morris, R.G.1
Anderson, E.2
Lynch, G.S.3
Baudry, M.4
-
32
-
-
0024093449
-
Glutamate neurotoxicity and diseases of the nervous system
-
Choi DW: Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988;1: 623-634.
-
(1988)
Neuron
, vol.1
, pp. 623-634
-
-
Choi, D.W.1
-
33
-
-
0011349374
-
Effects of ionotropic glutamate antagonists in stroke
-
Danysz W, Lodge D, Parsons CG (eds). Johnson City, F.P. Graham Publishing
-
O'Neill MJ, Lees K: Effects of ionotropic glutamate antagonists in stroke; in Danysz W, Lodge D, Parsons CG (eds): Ionotropic Glutamate Receptors as Therapeutic Targets. Johnson City, F.P. Graham Publishing, 2002, pp 403-447.
-
(2002)
Ionotropic Glutamate Receptors as Therapeutic Targets
, pp. 403-447
-
-
O'Neill, M.J.1
Lees, K.2
-
34
-
-
0025360229
-
Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones
-
Iino M, Ozawa S, Tsuzuki K: Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones. J Physiol 1990;424:151-165.
-
(1990)
J Physiol
, vol.424
, pp. 151-165
-
-
Iino, M.1
Ozawa, S.2
Tsuzuki, K.3
-
35
-
-
0032192550
-
Neuropharmacology of AMPA and kainate receptors
-
Bleakman D, Lodge D: Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 1998;37:1187-1204.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1187-1204
-
-
Bleakman, D.1
Lodge, D.2
-
36
-
-
0030483662
-
Stereoselective effects-of 2,3-benzodiazepines in vivo: Electrophysiology and neuroprotection studies
-
Lodge D, Bond A, O'Neill MJ, Hicks CA, Jones MG: Stereoselective effects-of 2,3-benzodiazepines in vivo: Electrophysiology and neuroprotection studies. Neuropharmacology 1996;35:1681-1688.
-
(1996)
Neuropharmacology
, vol.35
, pp. 1681-1688
-
-
Lodge, D.1
Bond, A.2
O'Neill, M.J.3
Hicks, C.A.4
Jones, M.G.5
-
37
-
-
0030483692
-
Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: Stereospecificity and selectivity profiles
-
Bleakman D, Ballyk BA, Schoepp DD, et al: Activity of 2, 3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: Stereospecificity and selectivity profiles. Neuropharmacology 1996;35:1689-1702.
-
(1996)
Neuropharmacology
, vol.35
, pp. 1689-1702
-
-
Bleakman, D.1
Ballyk, B.A.2
Schoepp, D.D.3
-
38
-
-
0029240274
-
Review: Neurotransmitter receptors. II. AMPA and kainate receptors
-
Bettler B, Mulle C: Review: Neurotransmitter receptors. II. AMPA and kainate receptors. Neuropharmacology 1995;34:123-139.
-
(1995)
Neuropharmacology
, vol.34
, pp. 123-139
-
-
Bettler, B.1
Mulle, C.2
-
39
-
-
0032191984
-
Decahydroisoquinolines: Novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia
-
O'Neill MJ, Bond A, Ornstein PL, et al: Decahydroisoquinolines: Novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia. Neuropharmacology 1998;37:1211-1222.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1211-1222
-
-
O'Neill, M.J.1
Bond, A.2
Ornstein, P.L.3
-
40
-
-
0030863091
-
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission
-
Clarke VR, Ballyk BA, Hoo KH, et al: A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission. Nature 1997;389:599-603.
-
(1997)
Nature
, vol.389
, pp. 599-603
-
-
Clarke, V.R.1
Ballyk, B.A.2
Hoo, K.H.3
-
41
-
-
0034073145
-
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia
-
O'Neill MJ, Bogaert L, Hicks CA, et al: LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia. Neuropharmacology 2000;39:1575-1588.
-
(2000)
Neuropharmacology
, vol.39
, pp. 1575-1588
-
-
O'Neill, M.J.1
Bogaert, L.2
Hicks, C.A.3
-
42
-
-
0036321170
-
Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures
-
Smolders I, Bortolotto ZA, Clarke VR, et al: Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures. Nat Neurosci 2002;5:796-804.
-
(2002)
Nat Neurosci
, vol.5
, pp. 796-804
-
-
Smolders, I.1
Bortolotto, Z.A.2
Clarke, V.R.3
-
43
-
-
0033057319
-
New perspectives for the development of selective metabotropic glutamate receptor ligands
-
Pin JP, De Colle C, Bessis AS, Acher F: New perspectives for the development of selective metabotropic glutamate receptor ligands. Eur J Pharmacol 1999;375:277-294.
-
(1999)
Eur J Pharmacol
, vol.375
, pp. 277-294
-
-
Pin, J.P.1
De Colle, C.2
Bessis, A.S.3
Acher, F.4
-
44
-
-
0029187946
-
The metabotropic glutamate receptors: Structure and functions
-
Pin JP, Duvoisin R: The metabotropic glutamate receptors: Structure and functions. Neuropharmacology 1995;34:1-26.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1-26
-
-
Pin, J.P.1
Duvoisin, R.2
-
45
-
-
0032834028
-
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
-
Schoepp DD, Jane DE, Monn JA: Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 1999;38:1431-1476.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1431-1476
-
-
Schoepp, D.D.1
Jane, D.E.2
Monn, J.A.3
-
46
-
-
0034078492
-
Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells
-
Chuang SC, Bianchi R, Wong RK: Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells. J Neurophysiol 2000;83:2844-2853.
-
(2000)
J Neurophysiol
, vol.83
, pp. 2844-2853
-
-
Chuang, S.C.1
Bianchi, R.2
Wong, R.K.3
-
47
-
-
0030821474
-
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus
-
Shigemoto R, Kinoshita A, Wada E, et al: Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci 1997;17:7503-7522.
-
(1997)
J Neurosci
, vol.17
, pp. 7503-7522
-
-
Shigemoto, R.1
Kinoshita, A.2
Wada, E.3
-
48
-
-
0033004346
-
Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors
-
Ferraguti F, Baldani-Guerra B, Corsi M, Na-kanishi S, Corti C: Activation of the extracellu-lar signal-regulated kinase 2 by metabotropic glutamate receptors. Eur J Neurosci 1999;11: 2073-2082.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 2073-2082
-
-
Ferraguti, F.1
Baldani-Guerra, B.2
Corsi, M.3
Nakanishi, S.4
Corti, C.5
-
49
-
-
0032514188
-
Human metabotropic glutamate receptor 2 couples to the MAP kinase cascade in Chinese hamster ovary cells
-
Phillips T, Barnes A, Scott S, Emson P, Rees S: Human metabotropic glutamate receptor 2 couples to the MAP kinase cascade in Chinese hamster ovary cells. Neuroreport 1998;9:2335-2339.
-
(1998)
Neuroreport
, vol.9
, pp. 2335-2339
-
-
Phillips, T.1
Barnes, A.2
Scott, S.3
Emson, P.4
Rees, S.5
-
50
-
-
0032791811
-
Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795
-
Kingston AE, O'Neill MJ, Lam A, Bales KR, Monn JA, Schoepp DD: Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795. Eur J Pharmacol 1999;377:155-165.
-
(1999)
Eur J Pharmacol
, vol.377
, pp. 155-165
-
-
Kingston, A.E.1
O'Neill, M.J.2
Lam, A.3
Bales, K.R.4
Monn, J.A.5
Schoepp, D.D.6
-
51
-
-
0033842964
-
Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: Investigations into possible mechanism of action in vivo
-
Bond A, Jones NM, Hicks CA, et al: Neuropro-tective effects of LY379268, a selective mGlu2/3 receptor agonist: Investigations into possible mechanism of action in vivo. J Pharmacol Exp Ther 2000;294:800-809.
-
(2000)
J Pharmacol Exp Ther
, vol.294
, pp. 800-809
-
-
Bond, A.1
Jones, N.M.2
Hicks, C.A.3
-
52
-
-
0034068655
-
Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine
-
Berl
-
Cartmell J, Monn JA, Schoepp DD: Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine. Psychopharmacology (Berl) 2000;148:423-429.
-
(2000)
Psychopharmacology
, vol.148
, pp. 423-429
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
53
-
-
0034852645
-
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
-
Bruno V, Battaglia G, Copani A, et al: Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J Cereb Blood Flow Metab 2001;21:1013-1033.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1013-1033
-
-
Bruno, V.1
Battaglia, G.2
Copani, A.3
-
54
-
-
0036068715
-
Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways
-
Iacovelli L, Bruno V, Salvatore L, et al: Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways. J Neurochem 2002;82:216-223.
-
(2002)
J Neurochem
, vol.82
, pp. 216-223
-
-
Iacovelli, L.1
Bruno, V.2
Salvatore, L.3
-
55
-
-
0032710970
-
Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease
-
Ikonomovic MD, Mizukami K, Warde D, et al: Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease. Exp Neurol 1999;160:194-204.
-
(1999)
Exp Neurol
, vol.160
, pp. 194-204
-
-
Ikonomovic, M.D.1
Mizukami, K.2
Warde, D.3
-
56
-
-
0034938257
-
Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease
-
Hynd MR, Scott HL, Dodd PR: Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease. J Neurochem 2001;78:175-182.
-
(2001)
J Neurochem
, vol.78
, pp. 175-182
-
-
Hynd, M.R.1
Scott, H.L.2
Dodd, P.R.3
-
57
-
-
0035188745
-
N-methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease
-
Sze C, Bi H, Kleinschmidt-DeMasters BK, Filley CM, Martin LJ: N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease. J Neurol Sci 2001;182:151-159.
-
(2001)
J Neurol Sci
, vol.182
, pp. 151-159
-
-
Sze, C.1
Bi, H.2
Kleinschmidt-DeMasters, B.K.3
Filley, C.M.4
Martin, L.J.5
-
58
-
-
0030785768
-
Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain
-
Ulas J, Cotman CW: Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience 1997;79:973-982.
-
(1997)
Neuroscience
, vol.79
, pp. 973-982
-
-
Ulas, J.1
Cotman, C.W.2
-
59
-
-
0036166948
-
The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease
-
Panegyres PK, Zafiris-Toufexis K, Kakulas BA: The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease. J Neural Transm 2002;109:77-89.
-
(2002)
J Neural Transm
, vol.109
, pp. 77-89
-
-
Panegyres, P.K.1
Zafiris-Toufexis, K.2
Kakulas, B.A.3
-
60
-
-
0037102726
-
N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease
-
Bi H, Sze CI: N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease. J Neurol Sci 2002;200:11-18.
-
(2002)
J Neurol Sci
, vol.200
, pp. 11-18
-
-
Bi, H.1
Sze, C.I.2
-
61
-
-
0033133588
-
Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease
-
Wakabayashi K, Narisawa-Saito M, Iwakura Y, et al: Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease. Neurobiol Aging 1999;20:287-295.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 287-295
-
-
Wakabayashi, K.1
Narisawa-Saito, M.2
Iwakura, Y.3
-
62
-
-
0030777850
-
Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant
-
Berl
-
Thorns V, Mallory M, Hansen L, Masliah E: Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant. Acta Neuropathol (Berl) 1997;94:539-548.
-
(1997)
Acta Neuropathol
, vol.94
, pp. 539-548
-
-
Thorns, V.1
Mallory, M.2
Hansen, L.3
Masliah, E.4
-
63
-
-
0023939425
-
Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease
-
Cowburn R, Hardy J, Roberts P, Briggs R: Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease. Brain Res 1988;452:403-407.
-
(1988)
Brain Res
, vol.452
, pp. 403-407
-
-
Cowburn, R.1
Hardy, J.2
Roberts, P.3
Briggs, R.4
-
64
-
-
0026002790
-
Binding to the glycine site of the NMDA receptor complex in brains of patients with Alzheimer's disease
-
Del Bel EA, Slater P: Binding to the glycine site of the NMDA receptor complex in brains of patients with Alzheimer's disease. Neurosci Lett 1991;131:75-78.
-
(1991)
Neurosci Lett
, vol.131
, pp. 75-78
-
-
Del Bel, E.A.1
Slater, P.2
-
65
-
-
0027291657
-
NMDA, AMPA benzodiazepine binding site changes in Alzheimer's disease visual cortex
-
Carlson MD, Penney JB Jr, Young AB: NMDA, AMPA, and benzodiazepine binding site changes in Alzheimer's disease visual cortex. Neurobiol Aging 1993;14:343-352.
-
(1993)
Neurobiol Aging
, vol.14
, pp. 343-352
-
-
Carlson, M.D.1
Penney Jr., J.B.2
Young, A.B.3
-
67
-
-
0025269614
-
Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias
-
Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB: Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. J Neurol Neurosurg Psychiatry 1990;53:314-320.
-
(1990)
J Neurol Neurosurg Psychiatry
, vol.53
, pp. 314-320
-
-
Penney, J.B.1
Maragos, W.F.2
Greenamyre, J.T.3
Debowey, D.L.4
Hollingsworth, Z.5
Young, A.B.6
-
68
-
-
0023838104
-
Presynaptic and postsynaptic glutamatergic function in Alzheimer's disease
-
Cowburn R, Hardy J, Roberts P, Briggs R: Presynaptic and postsynaptic glutamatergic function in Alzheimer's disease. Neurosci Lett 1988;86:109-113.
-
(1988)
Neurosci Lett
, vol.86
, pp. 109-113
-
-
Cowburn, R.1
Hardy, J.2
Roberts, P.3
Briggs, R.4
-
69
-
-
0022546807
-
Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease
-
Geddes JW, Cotman CW: Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease. Neurosci Res 1986;3:672-678.
-
(1986)
Neurosci Res
, vol.3
, pp. 672-678
-
-
Geddes, J.W.1
Cotman, C.W.2
-
71
-
-
0027431836
-
NMDA receptor status in elderly normal individuals and those with Alzheimer's disease
-
Porter RH, Roberts PJ, Briggs RS: NMDA receptor status in elderly normal individuals and those with Alzheimer's disease. Ann NY Acad Sci 1993;695:50-53.
-
(1993)
Ann NY Acad Sci
, vol.695
, pp. 50-53
-
-
Porter, R.H.1
Roberts, P.J.2
Briggs, R.S.3
-
72
-
-
0028029855
-
Selective increase of NMDA-sensitive glutamate binding in the striatum of Parkinson's disease, Alzheimer's disease, and mixed Parkinson's disease/Alzheimer's disease patients: An autoradiographic study
-
Ulas J, Weihmuller FB, Brunner LC, Joyce JN, Marshall JF, Cotman CW: Selective increase of NMDA-sensitive glutamate binding in the striatum of Parkinson's disease, Alzheimer's disease, and mixed Parkinson's disease/Alzheimer's disease patients: An autoradiographic study. J Neurosci 1994;14:6317-6324.
-
(1994)
J Neurosci
, vol.14
, pp. 6317-6324
-
-
Ulas, J.1
Weihmuller, F.B.2
Brunner, L.C.3
Joyce, J.N.4
Marshall, J.F.5
Cotman, C.W.6
-
74
-
-
0033977117
-
L-glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients
-
Kuiper MA, Teerlink T, Visser JJ, Bergmans PL, Scheltens P, Wolters EC: L-Glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients. J Neural Transm 2000;107:183-189.
-
(2000)
J Neural Transm
, vol.107
, pp. 183-189
-
-
Kuiper, M.A.1
Teerlink, T.2
Visser, J.J.3
Bergmans, P.L.4
Scheltens, P.5
Wolters, E.C.6
-
75
-
-
0023270663
-
Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone
-
Hyman BT, Van Hoesen GW, Damasio AR: Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone. Ann Neurol 1987;22:37-40.
-
(1987)
Ann Neurol
, vol.22
, pp. 37-40
-
-
Hyman, B.T.1
Van Hoesen, G.W.2
Damasio, A.R.3
-
76
-
-
0028233830
-
Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity
-
Weiss JH, Yin HZ, Choi DW: Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity. Neuroscience 1994;60:659-664.
-
(1994)
Neuroscience
, vol.60
, pp. 659-664
-
-
Weiss, J.H.1
Yin, H.Z.2
Choi, D.W.3
-
77
-
-
0025822891
-
Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: Differential dependence on cholinergic neuronal loss
-
Page KJ, Everitt BJ, Robbins TW, Marston HM, Wilkinson LS: Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: Differential dependence on cholinergic neuronal loss. Neuroscience 1991;43:457-472.
-
(1991)
Neuroscience
, vol.43
, pp. 457-472
-
-
Page, K.J.1
Everitt, B.J.2
Robbins, T.W.3
Marston, H.M.4
Wilkinson, L.S.5
-
78
-
-
0029554331
-
AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease
-
Ikonomovic MD, Sheffield R, Armstrong DM: AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease. Hippocampus 1995;5:469-486.
-
(1995)
Hippocampus
, vol.5
, pp. 469-486
-
-
Ikonomovic, M.D.1
Sheffield, R.2
Armstrong, D.M.3
-
79
-
-
0028350662
-
AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease
-
Armstrong DM, Ikonomovic MD, Sheffield R, Wenthold RJ: AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease. Brain Res 1994;639:207-216.
-
(1994)
Brain Res
, vol.639
, pp. 207-216
-
-
Armstrong, D.M.1
Ikonomovic, M.D.2
Sheffield, R.3
Wenthold, R.J.4
-
80
-
-
0025785213
-
Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: An autoradiographic study of the hippocampus
-
Dewar D, Chalmers DT, Graham DI, McCul-loch J: Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: An autoradiographic study of the hippocampus. Brain Res 1991;553:58-64.
-
(1991)
Brain Res
, vol.553
, pp. 58-64
-
-
Dewar, D.1
Chalmers, D.T.2
Graham, D.I.3
McCulloch, J.4
-
81
-
-
0025687533
-
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum
-
Dewar D, Chalmers DT, Shand A, Graham DI, McCulloch J: Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum. Ann Neurol 1990;28:805-810.
-
(1990)
Ann Neurol
, vol.28
, pp. 805-810
-
-
Dewar, D.1
Chalmers, D.T.2
Shand, A.3
Graham, D.I.4
McCulloch, J.5
-
82
-
-
0025138490
-
Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type
-
Chalmers DT, Dewar D, Graham DI, Brooks DN, McCulloch J: Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type. Proc Natl Acad Sci USA 1990;87:1352-1356.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1352-1356
-
-
Chalmers, D.T.1
Dewar, D.2
Graham, D.I.3
Brooks, D.N.4
McCulloch, J.5
-
83
-
-
0026738851
-
Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: Non-N-methyl-D-aspartate receptors
-
Geddes JW, Ulas J, Brunner LC, Choe W, Cotman CW: Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: Non-N-methyl-D-aspartate receptors. Neuroscience 1992;50: 23-34.
-
(1992)
Neuroscience
, vol.50
, pp. 23-34
-
-
Geddes, J.W.1
Ulas, J.2
Brunner, L.C.3
Choe, W.4
Cotman, C.W.5
-
84
-
-
0025648609
-
Distribution of a kainate/AMPA receptor mRNA in normal and Alzheimer brain
-
Harrison PJ, Barton AJ, Najlerahim A, Pearson RC: Distribution of a kainate/AMPA receptor mRNA in normal and Alzheimer brain. Neuroreport 1990;1:149-152.
-
(1990)
Neuroreport
, vol.1
, pp. 149-152
-
-
Harrison, P.J.1
Barton, A.J.2
Najlerahim, A.3
Pearson, R.C.4
-
85
-
-
0028365919
-
AMPA/kainate receptor gene expression in normal and Alzheimer's disease hippocampus
-
Pellegrini-Giampietro DE, Bennett MV, Zukin RS: AMPA/kainate receptor gene expression in normal and Alzheimer's disease hippocampus. Neuroscience 1994;61:41-49.
-
(1994)
Neuroscience
, vol.61
, pp. 41-49
-
-
Pellegrini-Giampietro, D.E.1
Bennett, M.V.2
Zukin, R.S.3
-
86
-
-
0030930206
-
The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains
-
Ikonomovic MD, Mizukami K, Davies P, Hamilton R, Sheffield R, Armstrong DM: The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains. J Neuropathol Exp Neurol 1997;56:1018-1027.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 1018-1027
-
-
Ikonomovic, M.D.1
Mizukami, K.2
Davies, P.3
Hamilton, R.4
Sheffield, R.5
Armstrong, D.M.6
-
87
-
-
0342617716
-
Non-plaque dystrophic dendrites in Alzheimer hippocampus: A new pathological structure revealed by glutamate receptor immunocytochemistry
-
Aronica E, Dickson DW, Kress Y, Morrison JH, Zukin RS: Non-plaque dystrophic dendrites in Alzheimer hippocampus: A new pathological structure revealed by glutamate receptor immunocytochemistry. Neuroscience 1998;82:979-991.
-
(1998)
Neuroscience
, vol.82
, pp. 979-991
-
-
Aronica, E.1
Dickson, D.W.2
Kress, Y.3
Morrison, J.H.4
Zukin, R.S.5
-
88
-
-
0028952094
-
Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: A biochemical study
-
Yasuda RP, Ikonomovic MD, Sheffield R, Rubin RT, Wolfe BB, Armstrong DM: Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: A biochemical study. Brain Res 1995;678:161-167.
-
(1995)
Brain Res
, vol.678
, pp. 161-167
-
-
Yasuda, R.P.1
Ikonomovic, M.D.2
Sheffield, R.3
Rubin, R.T.4
Wolfe, B.B.5
Armstrong, D.M.6
-
89
-
-
0034658288
-
Caspase-mediated degradation of AMPA receptor subunits: A mechanism for preventing excitotoxic necrosis and ensuring apoptosis
-
Glazner GW, Chan SL, Lu C, Mattson MP: Caspase-mediated degradation of AMPA receptor subunits: A mechanism for preventing excitotoxic necrosis and ensuring apoptosis. J Neurosci 2000;20:3641-3649.
-
(2000)
J Neurosci
, vol.20
, pp. 3641-3649
-
-
Glazner, G.W.1
Chan, S.L.2
Lu, C.3
Mattson, M.P.4
-
90
-
-
0033179170
-
Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease
-
Chan SL, Griffin WS, Mattson MP: Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. J Neurosci Res 1999;57:315-323.
-
(1999)
J Neurosci Res
, vol.57
, pp. 315-323
-
-
Chan, S.L.1
Griffin, W.S.2
Mattson, M.P.3
-
91
-
-
0035033710
-
Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: Implications for neurological side effects of cancer therapy and neurodegenerative disorders
-
Lu C, Fu W, Mattson MP: Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: Implications for neurological side effects of cancer therapy and neurodegenerative disorders. Neurobiol Dis 2001;8:194-206.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 194-206
-
-
Lu, C.1
Fu, W.2
Mattson, M.P.3
-
92
-
-
0036372055
-
Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: Implications for synaptic plasticity and excitotoxic neuronal death
-
Lu C, Fu W, Salvesen GS, Mattson MP: Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: Implications for synaptic plasticity and excitotoxic neuronal death. Neuromolecular Med 2002;1:69-79.
-
(2002)
Neuromolecular Med
, vol.1
, pp. 69-79
-
-
Lu, C.1
Fu, W.2
Salvesen, G.S.3
Mattson, M.P.4
-
93
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
Berl
-
Raina AK, Hochman A, Zhu X, et al: Abortive apoptosis in Alzheimer's disease. Acta Neuropathol (Berl) 2001;101:305-310.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 305-310
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
-
94
-
-
0021285256
-
3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia
-
3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia. Brain Res 1984;310:376-378.
-
(1984)
Brain Res
, vol.310
, pp. 376-378
-
-
Pearce, B.R.1
Bowen, D.M.2
-
95
-
-
0033011390
-
Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury
-
Allen JW, Ivanova SA, Fan L, Espey MG, Basile AS, Faden AI: Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. J Pharmacol Exp Ther 1999;290:112-120.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 112-120
-
-
Allen, J.W.1
Ivanova, S.A.2
Fan, L.3
Espey, M.G.4
Basile, A.S.5
Faden, A.I.6
-
96
-
-
0035145543
-
Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction
-
Matarredona ER, Santiago M, Venero JL, Cano J, Machado A: Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction. J Neurochem 2001;76:351-360.
-
(2001)
J Neurochem
, vol.76
, pp. 351-360
-
-
Matarredona, E.R.1
Santiago, M.2
Venero, J.L.3
Cano, J.4
Machado, A.5
-
97
-
-
0029016730
-
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide
-
Copani A, Bruno V, Battaglia G, et al: Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. Mol Pharmacol 1995;47:890-897.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 890-897
-
-
Copani, A.1
Bruno, V.2
Battaglia, G.3
-
98
-
-
0026647040
-
Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia
-
Chiamulera C, Albertini P, Valerio E, Reggiani A: Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia. Eur J Pharmacol 1992;216:335-336.
-
(1992)
Eur J Pharmacol
, vol.216
, pp. 335-336
-
-
Chiamulera, C.1
Albertini, P.2
Valerio, E.3
Reggiani, A.4
-
99
-
-
0031028197
-
Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat
-
Miyamoto M, Ishida M, Shinozaki H: Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat. Neuroscience 1997;77:131-140.
-
(1997)
Neuroscience
, vol.77
, pp. 131-140
-
-
Miyamoto, M.1
Ishida, M.2
Shinozaki, H.3
-
100
-
-
0029156276
-
The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
-
Buisson A, Choi DW: The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy- phenylglycine selectively attenuates NMDA neurotox-icity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology 1995;34:1081-1087.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1081-1087
-
-
Buisson, A.1
Choi, D.W.2
-
101
-
-
0030031001
-
DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons
-
Buisson A, Yu SP, Choi DW: DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons. Eur J Neurosci 1996;8:138-143.
-
(1996)
Eur J Neurosci
, vol.8
, pp. 138-143
-
-
Buisson, A.1
Yu, S.P.2
Choi, D.W.3
-
102
-
-
0030852182
-
In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats
-
Battaglia G, Monn JA, Schoepp DD: In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats. Neurosci Lett 1997;229:161-164.
-
(1997)
Neurosci Lett
, vol.229
, pp. 161-164
-
-
Battaglia, G.1
Monn, J.A.2
Schoepp, D.D.3
-
103
-
-
0031757268
-
Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV
-
Kilbride J, Huang LQ, Rowan MJ, Anwyl R: Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV. Eur J Pharmacol 1998;356:149-157.
-
(1998)
Eur J Pharmacol
, vol.356
, pp. 149-157
-
-
Kilbride, J.1
Huang, L.Q.2
Rowan, M.J.3
Anwyl, R.4
-
104
-
-
0032403407
-
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta
-
Bruno V, Battaglia G, Casabona G, Copani A, Caciagli F, Nicoletti F: Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci 1998;18:9594-9600.
-
(1998)
J Neurosci
, vol.18
, pp. 9594-9600
-
-
Bruno, V.1
Battaglia, G.2
Casabona, G.3
Copani, A.4
Caciagli, F.5
Nicoletti, F.6
-
105
-
-
0034948146
-
Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission
-
Battaglia G, Bruno V, Pisani A, et al: Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission. Mol Cell Neurosci 2001;17:1071-1083.
-
(2001)
Mol Cell Neurosci
, vol.17
, pp. 1071-1083
-
-
Battaglia, G.1
Bruno, V.2
Pisani, A.3
-
106
-
-
0033046392
-
Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxy-phenylglycine (LY367385): Comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors
-
Bruno V, Battaglia G, Kingston A, et al: Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxy-phenylglycine (LY367385): Comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. Neuropharmacology 1999;38:199-207.
-
(1999)
Neuropharmacology
, vol.38
, pp. 199-207
-
-
Bruno, V.1
Battaglia, G.2
Kingston, A.3
-
107
-
-
0032969124
-
Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression
-
Pizzi M, Boroni F, Bianchetti KM, Memo M, Spano P: Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression. Eur J Neurosci 1999;11:2489-2496.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 2489-2496
-
-
Pizzi, M.1
Boroni, F.2
Bianchetti, K.M.3
Memo, M.4
Spano, P.5
-
108
-
-
0029131714
-
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
-
Bruno V, Copani A, Knopfel T, et al: Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology 1995;34:1089-1098.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1089-1098
-
-
Bruno, V.1
Copani, A.2
Knopfel, T.3
-
109
-
-
0029942307
-
Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices
-
Pizzi M, Consolandi O, Memo M, Spano PF: Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices. Eur J Neurosci 1996;8:1516-1521.
-
(1996)
Eur J Neurosci
, vol.8
, pp. 1516-1521
-
-
Pizzi, M.1
Consolandi, O.2
Memo, M.3
Spano, P.F.4
-
110
-
-
0035924328
-
Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia
-
Bao WL, Williams AJ, Faden AI, Tortella FC: Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia. Brain Res 2001;922:173-179.
-
(2001)
Brain Res
, vol.922
, pp. 173-179
-
-
Bao, W.L.1
Williams, A.J.2
Faden, A.I.3
Tortella, F.C.4
-
111
-
-
84886422548
-
Pharmacology and neuroprotective actions of mGlu receptor ligands
-
O'Neill MJ: Pharmacology and neuroprotective actions of mGlu receptor ligands. Dev Med Child Neurol Suppl 2001;86:13-15.
-
(2001)
Dev Med Child Neurol Suppl
, vol.86
, pp. 13-15
-
-
O'Neill, M.J.1
-
112
-
-
0029121515
-
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
-
Bruno V, Battaglia G, Copani A, et al: Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. Eur J Neurosci 1995;7:1906-1913.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 1906-1913
-
-
Bruno, V.1
Battaglia, G.2
Copani, A.3
-
113
-
-
0034280739
-
Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death
-
Bruno V, Battaglia G, Ksiazek I, et al: Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death. J Neurosci 2000;20: 6413-6420.
-
(2000)
J Neurosci
, vol.20
, pp. 6413-6420
-
-
Bruno, V.1
Battaglia, G.2
Ksiazek, I.3
-
114
-
-
0033034991
-
(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo
-
Gasparini F, Bruno V, Battaglia G, et al: (R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. J Pharmacol Exp Ther 1999;289:1678-1687.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1678-1687
-
-
Gasparini, F.1
Bruno, V.2
Battaglia, G.3
-
116
-
-
0035800188
-
Differential expression of group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS
-
Laslo P, Lipski J, Funk GD: Differential expression of group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS. Neuroreport 2001;12:1903-1908.
-
(2001)
Neuroreport
, vol.12
, pp. 1903-1908
-
-
Laslo, P.1
Lipski, J.2
Funk, G.D.3
-
117
-
-
0035881425
-
Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: Implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis
-
Tomiyama M, Kimura T, Maeda T, et al: Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: Implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis. J Neurol Sci 2001;189:65-69.
-
(2001)
J Neurol Sci
, vol.189
, pp. 65-69
-
-
Tomiyama, M.1
Kimura, T.2
Maeda, T.3
-
118
-
-
0033019102
-
The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains
-
Berl
-
Oka A, Takashima S: The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains. Acta Neuropathol (Berl) 1999;97:275-278.
-
(1999)
Acta Neuropathol
, vol.97
, pp. 275-278
-
-
Oka, A.1
Takashima, S.2
-
119
-
-
0029016730
-
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide
-
Copani A, Bruno V, Battaglia G, et al: Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. Mol Pharmacol 1995;47:890-897.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 890-897
-
-
Copani, A.1
Bruno, V.2
Battaglia, G.3
-
120
-
-
0029147583
-
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
-
Lee RK, Wurtman RJ, Cox AJ, Nitsch RM: Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc Natl Acad Sci USA 1995;92:8083-8087.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8083-8087
-
-
Lee, R.K.1
Wurtman, R.J.2
Cox, A.J.3
Nitsch, R.M.4
-
121
-
-
0029935359
-
Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats
-
Lee RK, Jimenez J, Cox AJ, Wurtman RJ: Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats. Ann NY Acad Sci 1996;777:338-343.
-
(1996)
Ann NY Acad Sci
, vol.777
, pp. 338-343
-
-
Lee, R.K.1
Jimenez, J.2
Cox, A.J.3
Wurtman, R.J.4
-
122
-
-
0030944118
-
Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP
-
Lee RK, Wurtman RJ: Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP. J Neurochem 1997;68:1830-1835.
-
(1997)
J Neurochem
, vol.68
, pp. 1830-1835
-
-
Lee, R.K.1
Wurtman, R.J.2
-
123
-
-
0029841562
-
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
-
Furukawa K, Sopher BL, Rydel RE, et al: Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J Neurochem 1996;67:1882-1896.
-
(1996)
J Neurochem
, vol.67
, pp. 1882-1896
-
-
Furukawa, K.1
Sopher, B.L.2
Rydel, R.E.3
-
124
-
-
0028168596
-
Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury
-
Smith-Swintosky VL, Pettigrew LC, Craddock SD, Culwell AR, Rydel RE, Mattson MP: Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury. J Neurochem 1994;63:781-784.
-
(1994)
J Neurochem
, vol.63
, pp. 781-784
-
-
Smith-Swintosky, V.L.1
Pettigrew, L.C.2
Craddock, S.D.3
Culwell, A.R.4
Rydel, R.E.5
Mattson, M.P.6
-
125
-
-
0033571938
-
Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
-
Otani S, Auclair N, Desce JM, Roisin MP, Crepel F: Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. J Neurosci 1999;19:9788-9802.
-
(1999)
J Neurosci
, vol.19
, pp. 9788-9802
-
-
Otani, S.1
Auclair, N.2
Desce, J.M.3
Roisin, M.P.4
Crepel, F.5
-
126
-
-
0034797352
-
Differential activation of neuronal ERK, JNK/ SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis
-
Zhu X, Castellani RJ, Takeda A, et al: Differential activation of neuronal ERK, JNK/ SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis. Mech Ageing Dev 2001;123:39-46.
-
(2001)
Mech Ageing Dev
, vol.123
, pp. 39-46
-
-
Zhu, X.1
Castellani, R.J.2
Takeda, A.3
-
127
-
-
0035142804
-
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
-
Zhu X, Raina AK, Rottkamp CA, et al: Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem 2001;76:435-441.
-
(2001)
J Neurochem
, vol.76
, pp. 435-441
-
-
Zhu, X.1
Raina, A.K.2
Rottkamp, C.A.3
-
128
-
-
0033782845
-
Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
-
Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA: Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol 2000;59: 880-888.
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 880-888
-
-
Zhu, X.1
Rottkamp, C.A.2
Boux, H.3
Takeda, A.4
Perry, G.5
Smith, M.A.6
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