DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons

European Journal of Neuroscience

Volumn 8, Issue 1, 1996, Pages 138-143

  Buisson, Alain ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP; Cortical neurons; Excitotoxicity; Glutamate; Metabotropic receptors

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; BUCLADESINE; GLUTAMATE RECEPTOR AGONIST; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; PERTUSSIS TOXIN; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; FETUS; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BUCLADESINE; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP; CYCLOPROPANES; GLYCINE; KAINIC ACID; MEMBRANE POTENTIALS; MICE; N-METHYLASPARTATE; NEURONS; NEUROTOXINS; PERTUSSIS TOXIN; RECEPTORS, METABOTROPIC GLUTAMATE; VIRULENCE FACTORS, BORDETELLA;

EID: 0030031001     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01174.x     Document Type: Article

References (2)

1. Aleppo, G., Pisani, A., Copani, A., Bruno, V., Aronica, E., D'Agata, V., Canonico, P. L. and Nicoletti, F. (1992) Metabotropic glutamate receptors and neuronal toxicity. In Bazan, N. G. et al. (eds), Neurobiology of Essential Fatty Acids. Plenum Press, New York, pp. 137-145.
2. Ambrosini, A., Bresciani, L., Fracchia, S., Brunello, N. and Racagni, G. (1995) Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro. Mol. Pharmacol., 47, 1057-1064.