Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction

Journal of Neurochemistry

Volumn 76, Issue 2, 2001, Pages 351-360

  Matarredona, Esperanza R ^a   Santiago, Marti ^a   Venero, Jose L ^a   Cano, Josefina ^a   Machado, Alberto ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

1 methyl 4 phenylpyridinium; Dopamine release; Metabotropic glutamate receptors; Microdialysis; Microglia, rat striatum

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENTARY DNA; CYCLOHEXIMIDE; DOPAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE RECEPTOR; MESSENGER RNA; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; MONOCLONAL ANTIBODY; NEUROPROTECTIVE AGENT; TRANSFORMING GROWTH FACTOR BETA; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN PROTECTION; DOPAMINE RELEASE; DOPAMINERGIC SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; MICRODIALYSIS; MICROGLIA; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; BENZOATES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORPUS STRIATUM; CYCLOPROPANES; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINE AGENTS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICRODIALYSIS; MICROGLIA; MPTP POISONING; NEURONS; PRESYNAPTIC TERMINALS; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER;

ANIMALIA;

EID: 0035145543     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00056.x     Document Type: Article

References (51)

1. Selective acid vulnerability of dopaminergic neurons and its recovery by brain-derived neurotrophic factor
2. Modulation of excitotoxic damage in the neostriatum by metabotropic glutamate receptors
3. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
4. Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death
5. +
6. Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia
7. NMDA antagonists partially protect MPTP induced neurotoxicity in mice
8. Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death
9. The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signalling
10. Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β
11. Group I mGlu receptor modulation of dopamine release in the rat striatum in vivo
12. The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
13. +)
14. + elimination in the mouse striatum
15. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
16. Identification of potential compounds promoting BDNF production in nigral dopaminergic neurons: Clinical implication in Parkinson's disease
17. Pharmacology and functions of metabotropic glutamate receptors
18. Activation of metabotropic glutamate receptors protects neurons against apoptosis induced by beta-amyloid peptide
19. Molecular profile of reactive astrocytes-implications for their role in neurologic disease
20. The N-methyl-D)-aspartate antagonist MK-801 fails to protect dopaminergic neurons from MPTP toxicity in vitro
21. + rat model of substantia nigra degeneration
22. Functional recovery in parkinsonian monkeys treated with GDNF
23. Brain-derived and glial cell line-derived neurotrophic factors protect a catecholamine cell line from dopamine-induced cell death
24. Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: Subtype-specific coupling to ion channels
25. by dopamine neurons explains selective toxicity
26. Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen-glucose deprivation-induced neuronal death
27. Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors
28. I-Amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties
29. Microglia: A sensor for pathological events in the CNS
30. Do NMDA receptor antagonists protect against MPTP toxicity? Biochemical and immunocytochemical analyses in black mice
31. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
32. + toxicity in striatal dopaminergic terminals: Possible involvement of ascorbate
33. Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat
34. Brain-derived growth factor and nerve growth factor concentration are decreased in the substantia nigra in Parkinson's disease
35. Metabotropic receptors in excitotoxicity: (S)-4C3HPG protects against striatal quinolinic acid lesions
36. The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations
37. The metabotropic glutamate receptors: Structure and function
38. +) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase
39. Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes
40. + neurotoxicity by N-methyl-D-aspartate antagonists
41. BDNF attenuates the effects of intrastriatal injection of 6-hydroxydopamine
42. Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos
43. MK-801 fails to protect against the dopaminergic neuropathology produced by systemic MPTP in mice or intranigral MPTP in rats
44. +) nigral toxicity in the rat by prior decortication of MK-801 treatment: A stereological estimate of neuronal loss
45. + produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism
46. + neurotoxicity by N-methyl-D-aspartate antagonists
47. Regulation of striatal dopamine release by metabotropic glutamate receptors
48. Metabotropic glutamate receptors prevent nitric oxide-induced programmed cell death
49. Scope and limitations of in vivo brain dialysis: A comparison of its application to various neurotransmitter systems
50. Astrocytes retrovirally transducted with BDNF elicit behavioural improvements in a rat model of Parkinson's disease