Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 18, 1998, Pages 10499-10504

  Suzuki, Nobutaka ^a   Del Villar, Keith ^a   Tamanoi, Fuyuhiko ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (8 CHLORO 5,6 DIHYDRO 11H BENZO[5,6]CYCLOHEPTA[1,2 B]PYRIDIN 11 YLIDENE) 1 (4 PYRIDYLACETYL)PIPERIDINE; ENZYME INHIBITOR; PROTEIN FARNESYLTRANSFERASE INHIBITOR; SCH 56582; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE S PHASE; CELL STRUCTURE; CONCENTRATION RESPONSE; CYTOSKELETON; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; KIDNEY EPITHELIUM; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT;

ACTINS; ALKYL AND ARYL TRANSFERASES; CELL LINE, TRANSFORMED; CYTOSKELETON; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; G2 PHASE; GENES, RAS; HUMANS; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOSIS;

ANIMALIA;

EID: 0032169673     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.18.10499     Document Type: Article

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