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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 6, 2001, Pages 761-764

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

(11) Ohkanda, Junko a Lockman, Jeffrey W a Yokoyama, Kohei b Gelb, Michael H b Croft, Simon L c Kendrick, Howard c Harrell, Maria Isabel d Feagin, Jean E d,e Blaskovich, Michelle A f Sebti, Said M f Hamilton, Andrew D a

a YALE UNIVERSITY (United States)

b UNIVERSITY OF WASHINGTON (United States)

c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE (United Kingdom)

d SEATTLE BIOMEDICAL RESEARCH INSTITUTE (United States)

e UNIVERSITY OF WASHINGTON (United States)

f H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; PROTEIN FARNESYLTRANSFERASE INHIBITOR;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; NONHUMAN; PLASMODIUM FALCIPARUM;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTIMALARIALS; DRUG DESIGN; DRUG RESISTANCE; ENZYME INHIBITORS; IMIDAZOLES; INHIBITORY CONCENTRATION 50; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 0035953020 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00055-5 Document Type: Article

Times cited : (78)

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