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Volumn 6, Issue 6, 2000, Pages 2318-2325

Comparison of potential markers of farnesyltransferase inhibition

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN P21;

EID: 0034084316     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (118)

References (47)
  • 1
    • 0026735063 scopus 로고
    • Protein isoprenylation and methylation at carboxyl-terminal cysteine residues
    • Clarke, S. Protein isoprenylation and methylation at carboxyl-terminal cysteine residues. Annu. Rev. Biochem., 61: 355-386, 1992.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 355-386
    • Clarke, S.1
  • 2
    • 0026436279 scopus 로고
    • The prenylation of proteins
    • Sinensky, M., and Lutz, R. J. The prenylation of proteins. Bioessays, 14: 25-31, 1992.
    • (1992) Bioessays , vol.14 , pp. 25-31
    • Sinensky, M.1    Lutz, R.J.2
  • 3
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer. A review
    • Bos, J. L. ras oncogenes in human cancer. A review. Cancer Res., 49: 4682-4689, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 4
    • 0030749458 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors and cancer treatment: Targeting simply ras?
    • Cox, A. D., and Der, C. J. Farnesyltransferase inhibitors and cancer treatment: targeting simply ras? Biochim. Biophys. Acta, 1333: F51-F71, 1997.
    • (1997) Biochim. Biophys. Acta , vol.1333
    • Cox, A.D.1    Der, C.J.2
  • 5
    • 0030962347 scopus 로고    scopus 로고
    • The potential of farnesyltransferase inhibitors as cancer chemotherapeutics
    • Gibbs, J. B., and Oliff, A. The potential of farnesyltransferase inhibitors as cancer chemotherapeutics. Annu. Rev. Pharmacol. Toxicol., 37: 143-166, 1997.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 143-166
    • Gibbs, J.B.1    Oliff, A.2
  • 6
    • 0031993476 scopus 로고    scopus 로고
    • Protein prenylation: From discovery to prospects for cancer treatment
    • Gelb, M. H., Scholten, J. D., and Sebolt-Leopold, J. S. Protein prenylation: from discovery to prospects for cancer treatment. Curr. Opin. Chem. Biol., 2: 40-48, 1998.
    • (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 40-48
    • Gelb, M.H.1    Scholten, J.D.2    Sebolt-Leopold, J.S.3
  • 7
    • 0033014304 scopus 로고    scopus 로고
    • RAS and leukemia: From basic mechanisms to gene-directed therapy
    • Beaupre, D. M., and Kurzrock, R. RAS and leukemia: from basic mechanisms to gene-directed therapy. J. Clin. Oncol., 17: 1071-1079, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1071-1079
    • Beaupre, D.M.1    Kurzrock, R.2
  • 8
    • 0032704708 scopus 로고    scopus 로고
    • Ras protein farnesyltransferase. A strategic target for anticancer therapeutic development
    • Rowinsky, E. K., Windle, J. J., and Von Hoff, D. D. Ras protein farnesyltransferase. A strategic target for anticancer therapeutic development. J. Clin. Oncol., 17: 3631-3652, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3631-3652
    • Rowinsky, E.K.1    Windle, J.J.2    Von Hoff, D.D.3
  • 9
    • 0026895892 scopus 로고
    • Protein prenylation: Key to ras function and cancer intervention?
    • Khosravi-Far, R., Cox, A. D., Kato, K., and Der, C. J. Protein prenylation: key to ras function and cancer intervention? Cell Growth Differ., 3: 461-469, 1992.
    • (1992) Cell Growth Differ. , vol.3 , pp. 461-469
    • Khosravi-Far, R.1    Cox, A.D.2    Kato, K.3    Der, C.J.4
  • 10
    • 0033375466 scopus 로고    scopus 로고
    • Farnesyl protein transferase inhibitors and other therapies targeting the ras signal transduction pathway
    • End, D. W. Farnesyl protein transferase inhibitors and other therapies targeting the ras signal transduction pathway. Investig. New Drugs, 17: 241-258, 1999.
    • (1999) Investig. New Drugs , vol.17 , pp. 241-258
    • End, D.W.1
  • 12
    • 0028973293 scopus 로고
    • Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes
    • Lerner, E. C., Qian, Y., Blaskovich, M. A., Fossum, R. D., Vogt, A., Sun, J., Cox, A. D., Der, C. J., Hamilton, A. D., and Sebti, S. M. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J. Biol. Chem., 270: 26802-26806, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26802-26806
    • Lerner, E.C.1    Qian, Y.2    Blaskovich, M.A.3    Fossum, R.D.4    Vogt, A.5    Sun, J.6    Cox, A.D.7    Der, C.J.8    Hamilton, A.D.9    Sebti, S.M.10
  • 13
    • 0029166504 scopus 로고
    • Inhibition of ras function in vitro and in vivo using inhibitors of farnesyl-protein transferase
    • Kohl, N. E., Wilson, F. R., Thomas, T. J., Bock, R. L., Mosser, S. D., Oliff, A., and Gibbs, J. B. Inhibition of ras function in vitro and in vivo using inhibitors of farnesyl-protein transferase. Methods Enzymol., 255: 378-386, 1995.
    • (1995) Methods Enzymol. , vol.255 , pp. 378-386
    • Kohl, N.E.1    Wilson, F.R.2    Thomas, T.J.3    Bock, R.L.4    Mosser, S.D.5    Oliff, A.6    Gibbs, J.B.7
  • 15
    • 0031584823 scopus 로고    scopus 로고
    • Geranylgeranyl as well as farnesyl moiety is transferred to p21 overproduced in adrenocortical cells transformed with c-Ha-rasEJ oncogene
    • Osman, H., Mazet, J. L., Maume, G., and Maume, B. F. Geranylgeranyl as well as farnesyl moiety is transferred to p21 overproduced in adrenocortical cells transformed with c-Ha-rasEJ oncogene. Biochem. Biophys. Res. Commun., 231: 789-792, 1997.
    • (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 789-792
    • Osman, H.1    Mazet, J.L.2    Maume, G.3    Maume, B.F.4
  • 18
    • 0032541625 scopus 로고    scopus 로고
    • Non-ras targets of farnesyltransferase inhibitors. Focus on Rho
    • Lebowitz, P. F., and Prendergast, G. C. Non-ras targets of farnesyltransferase inhibitors. Focus on Rho. Oncogene, 17: 1439-1445, 1998.
    • (1998) Oncogene , vol.17 , pp. 1439-1445
    • Lebowitz, P.F.1    Prendergast, G.C.2
  • 19
    • 0033016719 scopus 로고    scopus 로고
    • Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated Rho B
    • Du, W., Lebowitz, P. F., and Prendergast, G. C. Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated Rho B. Mol. Cell. Biol., 19: 1831-1840, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1831-1840
    • Du, W.1    Lebowitz, P.F.2    Prendergast, G.C.3
  • 20
    • 0002524987 scopus 로고    scopus 로고
    • The Hsp90 chaperone family
    • D. S. Latchman (ed.), New York: Springer-Verlag
    • Neckers, L., Mimnaugh, E., and Schulte, T. W. The Hsp90 chaperone family. In: D. S. Latchman (ed.), Stress Proteins, pp. 9-42. New York: Springer-Verlag, 1999.
    • (1999) Stress Proteins , pp. 9-42
    • Neckers, L.1    Mimnaugh, E.2    Schulte, T.W.3
  • 22
    • 0022648101 scopus 로고
    • Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins
    • McKeon, F. D., Kirschner, M. W., and Caput, D. Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature (Lond.), 319: 463-468, 1986.
    • (1986) Nature (Lond.) , vol.319 , pp. 463-468
    • McKeon, F.D.1    Kirschner, M.W.2    Caput, D.3
  • 23
    • 0025362748 scopus 로고
    • Isoprenylation is required for the processing of the lamin A precursor
    • Beck, L. A., Hosick, T. J., and Sinensky, M. Isoprenylation is required for the processing of the lamin A precursor. J. Cell Biol., 110: 1489-1499, 1990.
    • (1990) J. Cell Biol. , vol.110 , pp. 1489-1499
    • Beck, L.A.1    Hosick, T.J.2    Sinensky, M.3
  • 25
    • 0031054691 scopus 로고    scopus 로고
    • In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease
    • Kilic, F., Dalton, M. B., Burrell, S. K., Mayer, J. P., Patterson, S. D., and Sinensky, M. In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease. J. Biol. Chem., 272: 5298-5304, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5298-5304
    • Kilic, F.1    Dalton, M.B.2    Burrell, S.K.3    Mayer, J.P.4    Patterson, S.D.5    Sinensky, M.6
  • 26
    • 0028237586 scopus 로고
    • An antibody which specifically recognizes prelamin A but not mature lamin A: Application to detection of blocks in farnesylation-dependent protein processing
    • Sinensky, M., Fantle, K., and Dalton, M. An antibody which specifically recognizes prelamin A but not mature lamin A: application to detection of blocks in farnesylation-dependent protein processing. Cancer Res., 54: 3229-3232, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3229-3232
    • Sinensky, M.1    Fantle, K.2    Dalton, M.3
  • 29
    • 0030880741 scopus 로고    scopus 로고
    • Increasing complexity of ras signal transduction: Involvement of Rho family proteins
    • Khosravi-Far, R., Campbell, S., Rossman, K. L., and Der, C. J. Increasing Complexity of ras signal transduction: involvement of Rho family proteins. Adv. Cancer, 72: 57-107, 1998.
    • (1998) Adv. Cancer , vol.72 , pp. 57-107
    • Khosravi-Far, R.1    Campbell, S.2    Rossman, K.L.3    Der, C.J.4
  • 30
    • 0033545565 scopus 로고    scopus 로고
    • Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells
    • Plattner, R., Gupta, S., Khosravi-Far, R., Sato, K. Y., Perucho, M., Der, C. J., and Stanbridge, E. J. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells. Oncogene, 18: 1807-1817, 1999.
    • (1999) Oncogene , vol.18 , pp. 1807-1817
    • Plattner, R.1    Gupta, S.2    Khosravi-Far, R.3    Sato, K.Y.4    Perucho, M.5    Der, C.J.6    Stanbridge, E.J.7
  • 33
    • 0024064963 scopus 로고
    • Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm
    • Loewinger, L., and McKeon, F. Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm. EMBO J., 7: 2301-2309, 1988.
    • (1988) EMBO J. , vol.7 , pp. 2301-2309
    • Loewinger, L.1    McKeon, F.2
  • 34
    • 0024313362 scopus 로고
    • Additional members of the rat liver lamin polypeptide family: Structural and immunological characterization
    • Kaufmann, S. H. Additional members of the rat liver lamin polypeptide family: structural and immunological characterization. J. Biol. Chem., 264: 13946-13955, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13946-13955
    • Kaufmann, S.H.1
  • 35
    • 0000375697 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of continuous daily oral SCH66336, a novel farnesyl transferase inhibitor, in patients with solid tumors
    • Eskens, F., Awada, A., Verweij, J., Cutler, D. L., Hanauske, A., and Piccart, M. Phase I and pharmacologic study of continuous daily oral SCH66336, a novel farnesyl transferase inhibitor, in patients with solid tumors. Proc. Am. Soc. Clin. Oncol., 18: 600, 1999.
    • (1999) Proc. Am. Soc. Clin. Oncol. , vol.18 , pp. 600
    • Eskens, F.1    Awada, A.2    Verweij, J.3    Cutler, D.L.4    Hanauske, A.5    Piccart, M.6
  • 36
    • 0030812207 scopus 로고    scopus 로고
    • Cytotoxic synergy between flavopiridol (NSC 649890, L86-8275) and various antineoplastic agents: Importance of sequence of administration
    • Bible, K., and Kaufmann, S. H. Cytotoxic synergy between flavopiridol (NSC 649890, L86-8275) and various antineoplastic agents: importance of sequence of administration. Cancer Res., 57: 3375-3380, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3375-3380
    • Bible, K.1    Kaufmann, S.H.2
  • 37
    • 0030933933 scopus 로고    scopus 로고
    • Altered formation of topotecan-stabilized topoisomerase I-DNA adducts in human leukemia cells
    • Kaufmann, S. H., Svingen, P. A., Gore, S. D., Armstrong, D. K., Cheng, Y-C., and Rowinsky, E. K. Altered formation of topotecan-stabilized topoisomerase I-DNA adducts in human leukemia cells. Blood, 89: 2098-2104, 1997.
    • (1997) Blood , vol.89 , pp. 2098-2104
    • Kaufmann, S.H.1    Svingen, P.A.2    Gore, S.D.3    Armstrong, D.K.4    Cheng, Y.-C.5    Rowinsky, E.K.6
  • 39
    • 0028893651 scopus 로고
    • Detection and quantitation of mutant K-ras codon 12 restriction fragments by capillary electrophoresis
    • Mitchell, C. E., Belinsky, S. A., and Lechner, J. F. Detection and quantitation of mutant K-ras codon 12 restriction fragments by capillary electrophoresis. Anal. Biochem., 224. 148-153, 1995.
    • (1995) Anal. Biochem. , vol.224 , pp. 148-153
    • Mitchell, C.E.1    Belinsky, S.A.2    Lechner, J.F.3
  • 40
    • 0022622668 scopus 로고
    • Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene
    • Valenzuela, D. M., and Groffen, J. Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras Oncogene. Nucleic Acids Res., 14: 843-852, 1986.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 843-852
    • Valenzuela, D.M.1    Groffen, J.2
  • 41
    • 0024399048 scopus 로고
    • Human lamin B contains a farnesylated cysteine residue
    • Farnsworth, C. C., Wolda, S. L., Gelb, M. H., and Glomset, J. A. Human lamin B contains a farnesylated cysteine residue. J. Biol. Chem., 264: 20422-20429, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20422-20429
    • Farnsworth, C.C.1    Wolda, S.L.2    Gelb, M.H.3    Glomset, J.A.4
  • 42
    • 0032818585 scopus 로고    scopus 로고
    • Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A
    • Rajesh, D., Schell, K., and Verma, A. K. Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A. Mol. Pharmacol., 56: 515-525, 1999.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 515-525
    • Rajesh, D.1    Schell, K.2    Verma, A.K.3
  • 43
    • 0026530145 scopus 로고
    • Invasive and metastatic properties of MCF-7 cells and rasH-transfected MCF-7 cell lines
    • Gelmann, E. P., Thompson, E. W., and Sommers, C. L. Invasive and metastatic properties of MCF-7 cells and rasH-transfected MCF-7 cell lines. Int. J. Cancer, 50: 665-669, 1992.
    • (1992) Int. J. Cancer , vol.50 , pp. 665-669
    • Gelmann, E.P.1    Thompson, E.W.2    Sommers, C.L.3
  • 44
    • 0029135061 scopus 로고
    • Assays for inhibitors of CAAX farnesyltransferase in vitro and in intact cells
    • James, G. L., Brown, M. S., and Goldstein, J. L. Assays for inhibitors of CAAX farnesyltransferase in vitro and in intact cells. Methods Enzymol., 255: 38-46, 1995.
    • (1995) Methods Enzymol. , vol.255 , pp. 38-46
    • James, G.L.1    Brown, M.S.2    Goldstein, J.L.3
  • 45
    • 0026747866 scopus 로고
    • Isoprenoid addition to Ras proteins is the critical modification for its membrane association and transforming activity
    • Kato, K., Cox, A. D., Hisaka, M. M., Graham, S. M., Buss, J. E., and Der, C. J. Isoprenoid addition to Ras proteins is the critical modification for its membrane association and transforming activity. Proc. Natl. Acad. Sci., USA, 89: 6403-6407, 1992.
    • (1992) Proc. Natl. Acad. Sci., USA , vol.89 , pp. 6403-6407
    • Kato, K.1    Cox, A.D.2    Hisaka, M.M.3    Graham, S.M.4    Buss, J.E.5    Der, C.J.6
  • 46
    • 0028835253 scopus 로고
    • A peptidomimetic inhibitor of farnesyl:Protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines
    • Sepp-Lorenzino, L., Ma, Z., Rands, E., Kohl, N. E., Gibbs, J. B., Oliff, A., and Rosen, N. A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines. Cancer Res., 55: 5302-5309, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5302-5309
    • Sepp-Lorenzino, L.1    Ma, Z.2    Rands, E.3    Kohl, N.E.4    Gibbs, J.B.5    Oliff, A.6    Rosen, N.7
  • 47
    • 0027320616 scopus 로고
    • Peptidomimetic inhibitors of Ras farnesylation and function in whole cells
    • Garcia, A. M., Rowell, C., Ackermann, K., Kowalcyzk, J. J., and Lewis, M. D. Peptidomimetic inhibitors of Ras farnesylation and function in whole cells. J. Biol. Chem., 268: 18415-18418, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18415-18418
    • Garcia, A.M.1    Rowell, C.2    Ackermann, K.3    Kowalcyzk, J.J.4    Lewis, M.D.5


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