-
10
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
(1996)
J Clin Oncol
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
-
11
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
Robert, N.J.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.M.7
Paton, V.8
Shak, S.9
Lieberman, G.10
-
12
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
-
14
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
15
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
16
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
17
-
-
85031473985
-
Glivec™ (imatinib mesylate) induces hematologic and cytogenetic responses in the majority of patients with chronic myeloid leukemia: Results of a phase II study
-
Orlando, Florida; December 7-11: Abstract
-
(2001)
rd Annual Meeting
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Resta, D.5
Zoellner, U.6
Capdeville, R.7
Talpaz, M.8
Druker, B.9
-
18
-
-
1642456935
-
Glivec™ (imatinib mesylate) induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase II study
-
Orlando, Florida; December 7-11: Abstract
-
(2001)
rd Annual Meeting
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.3
Goldman, J.M.4
Gambacorti-Passerini, C.5
Guilhot, F.6
Schiffer, C.A.7
Fischer, T.8
Niederwieser, D.9
O'Brien, S.G.10
-
19
-
-
1642579230
-
Glivec™ (imatinib mesylate) induces hematologic and cytogenetic responses in patients with chronic myeloid leukemia in myeloid blast crisis: Results of a phase II study
-
Orlando, Florida; December 7-11: Abstract
-
(2001)
rd Annual Meeting
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
Goldman, J.M.4
Miller, C.5
Ottmann, O.G.6
Schiffer, C.A.7
Talpaz, M.8
Guilhot, F.9
Deininger, M.W.N.10
-
21
-
-
0003300442
-
Molecular and chromosomal mechanisms of resistance in CML patients after STI571 (Glivec) therapy
-
Orlando, Florida; December 7-11: Abstract 1823
-
(2001)
rd Annual Meeting
-
-
Kreil, S.1
Muller, M.C.2
Lahaye, T.3
La Rosee, P.4
Corbin, A.S.5
Schoch, C.6
Cross, N.C.P.7
Berger, U.8
Rieder, H.9
Druker, B.J.10
-
22
-
-
0003294010
-
Point mutations clustered within the ATP binding region of BCR-ABL are common in patients with emerging Glivec resistance but not in Glivec non-responsive cases of CML
-
Orlando, Florida; December 7-11: Abstract 3204
-
(2001)
rd Annual Meeting
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
Grigg, A.4
Arthur, C.5
Taylor, K.6
Herrmann, R.7
Lynch, K.8
Hughes, T.9
-
25
-
-
0035929652
-
Roots of clinical resistance to STI-571 cancer therapy
-
(2001)
Science
, vol.293
, pp. 2163
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.3
La Rosee, P.4
Lahaye, T.5
Berger, U.6
Cross, N.C.7
Linkesch, W.8
Druker, B.J.9
Hehlmann, R.10
-
27
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
Andersson, L.C.4
Tervahartiala, P.5
Tuveson, D.6
Silberman, S.7
Capdeville, R.8
Dimitrijevic, S.9
Druker, B.10
-
28
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
Van Oosterom, A.T.1
Judson, I.2
Verweij, J.3
Stroobants, S.4
Donato Di Paola, E.5
Dimitrijevic, S.6
Martens, M.7
Webb, A.8
Sciot, R.9
Van Glabbeke, M.10
-
29
-
-
0000244046
-
Evaluation of the safety and efficacy of an oral molecularly-targeted therapy, STI571, in patients (Pts) with unresectable or metastatic gastrointestinal stromal tumors (GISTS) expressing C-KIT (CD117)
-
San Francisco, California; May 12-15: Abstract
-
th Annual Meeting
-
-
Blanke, C.D.1
Von Mehren, M.2
Joensuu, H.3
Roberts, P.J.4
Eisenberg, B.5
Heinrich, M.6
Druker, B.7
Tuveson, D.8
Dimitrijevic, S.9
Silberman, S.L.10
-
31
-
-
85031466263
-
Chronic myeloproliferative diseases with t(5;12) and a PDGFRB fusion gene: Complete cytogenetic remissions on STI571
-
Orlando, Florida; December 7-11: Abstract 3031
-
(2001)
rd Annual Meeting
-
-
Apperley, J.F.1
Schultheis, B.2
Chase, A.3
Steer, J.4
Bain, B.5
Dimitrijevic, S.6
Marin, D.7
Olavarria, E.8
Cross, N.9
Russell-Jones, R.10
-
36
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
Stiles, B.4
Thomas, G.5
Peterson, R.6
Frost, P.7
Gibbons, J.J.8
Wu, H.9
Sawyers, C.L.10
-
37
-
-
17944368972
-
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10320-10325
-
-
Podsypanina, K.1
Lee, R.T.2
Politis, C.3
Hennessey, I.4
Crane, A.5
Puc, J.6
Neshat, M.7
Wang, H.8
Yang, L.9
Gibbons, J.10
|