Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27(Kip1) into cyclin E/CDK2 complexes

Cancer Research

Volumn 59, Issue 10, 1999, Pages 2318-2323

  Cheney, I Wayne ^a   Neuteboom, Saskia T C ^a   Vaillancourt, Mei Ting ^a   Ramachandra, Muralidhara ^a   Bookstein, Robert ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; PHOSPHATIDYLINOSITOL 3 KINASE;

ADENOVIRUS; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL LINE; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE MUTATION; GENE OVEREXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC ANALYSIS; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; VIRUS RECOMBINANT;

ADENOVIRUSES, HUMAN; ANTIGEN-ANTIBODY COMPLEX; CDC2-CDC28 KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; GENETIC VECTORS; GLIOBLASTOMA; HUMANS; MACROMOLECULAR SUBSTANCES; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; S PHASE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033563157     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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