Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach

Pharmacology and Therapeutics

Volumn 95, Issue 1, 2002, Pages 1-20

  Chalker, Alison F ^a   Lunsford, R Dwayne ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Antibacterial drug development; Bacterial genomics

Indexed keywords

ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; LINEZOLID;

ALLELE; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; BACTERIAL INFECTION; BACTERIAL STRAIN; BIOINFORMATICS; CELL VIABILITY; CROSS RESISTANCE; DRUG EFFICACY; DRUG INDUSTRY; DRUG TARGETING; GENE SEQUENCE; HUMAN; METHODOLOGY; MOLECULAR GENETICS; MUTAGENESIS; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN FUNCTION; PUBLIC HEALTH; REVIEW; TRANSPOSON; VALIDATION PROCESS; BACTERIAL GENE; CHEMISTRY; DRUG DESIGN; GENETICS; GENOMICS;

ANTI-INFECTIVE AGENTS; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; GENES, BACTERIAL; GENOME, BACTERIAL; GENOMICS;

EID: 0035993441     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(02)00222-X     Document Type: Review

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