Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

Nature

Volumn 390, Issue 6660, 1997, Pages 580-586

  Fraser, Claire M ^a   Casjens, Sherwood ^b   Huang, Wai Mun ^b   Sutton, Granger G ^a   Clayton, Rebecca ^a   Lathigra, Raju ^c   White, Owen ^a   Ketchum, Karen A ^a   Dodson, Robert ^a   Hickey, Erin K ^a   Gwinn, Michelle ^a   Dougherty, Brian ^a   Tomb, Jean Francois ^a   Fleischmann, Robert D ^a   Richardson, Delwood ^a   Peterson, Jeremy ^a   Kerlavage, Anthony R ^a   Quackenbush, John ^a   Salzberg, Steven ^a   Hanson, Mark ^c   Van Vugt, Rene ^b   Palmer, Nanette ^b   Adams, Mark D ^a   Gocayne, Jeannine ^a   Weidman, Janice ^a   Utterback, Teresa ^a   Watthey, Larry ^a   McDonald, Lisa ^a   Artiach, Patricia ^a   Bowman, Cheryl ^a   Garland, Stacey ^a   Fujii, Claire ^a   Cotton, Matthew D ^a   Horst, Kurt ^a   Roberts, Kevin ^a   Hatch, Bonnie ^a   Smith, Hamilton O ^a   Venter, J Craig ^a   more..

^a J CRAIG VENTER INSTITUTE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BORRELIA BURGDORFERI; CHEMOTAXIS; CHROMOSOME ANALYSIS; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; ENERGY METABOLISM; GENE SEQUENCE; GENOME; NONHUMAN; PLASMID; PRIORITY JOURNAL; TELOMERE;

BIOLOGICAL TRANSPORT; BORRELIA BURGDORFERI GROUP; CHEMOTAXIS; CHROMOSOMES, BACTERIAL; DNA REPAIR; DNA, BACTERIAL; ENERGY METABOLISM; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; LYME DISEASE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN BIOSYNTHESIS; RECOMBINATION, GENETIC; REPLICATION ORIGIN; TELOMERE; TRANSCRIPTION, GENETIC;

EID: 0031470826     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/37551     Document Type: Article

References (49)

1. Steere, A. C. et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum. 20, 7 (1977).
2. Steere, A. C. Lyme disease. New Engl. J. Med. 321, 586-596 (1989).
3. Johnson, R. C., Schmidt, G. P., Hyde, F. W., Steigerwaalt, A. G. & Brenner, D. J. Borrelia burgdorferi sp. nov.: etiologic agent of Lyme disease. Int. J. Syst. Bacteriol. 34, 496-497 (1984).
4. Burgdorfer, W. et al. Lyme disease - a tick-borne spirochetosis? Science 216, 1317-1319 (1982).
5. Barbour, A. G., Burgdorfer, W., Hayes, S. F., Peter, O. & Aeschlimann, A. Isolation of a cultivable spirochete from Ixodes ricinus ticks of Switzerland. Curr. Microbiol. 8, 123-126 (1983).
6. Barbour, A. & Hayes, S. F. Biology of Borrelia species. Microbiol. Rev. 50, 381-400 (1986).
7. Baril, C., Richaud, C., Baranton, G. & Saint Girons, I. Linear chromosome of Borrelia burgdorferi. Res. Microbiol. 140, 507-516 (1989).
8. Ferdows, M. S. & Barbour, A. G. Megabase-sized linear DNA in the bacterium Borrelia burgdorferi, the Lyme disease agent. Proc. Natl Acac Sci. USA 86, 5969-5973 (1989).
9. Davidson, B., MacDougall, J. & Saint Girons, I. Physical map of the linear chromosome of the bacterium Borrelia burgdorferi 212, a causative agent of Lyme disease and localization of rRNA genes. J. Bacteriol. 174, 3766-3774 (1992).
10. Casjens, S. & Huang, W. M. Linear chromosome physical and genetic map of Borrelia burgdorferi, the Lyme disease agent. Mol. Microbiol. 8, 967-980 (1993).
11. Barbour, A. G. & Garon, C. F. Linear plasmids of the bacterium Borrelia burgdorferi have covalently dosed ends. Science 237, 409-411 (1987).
12. Barbour, A. G. Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent. J. Clin. Microbiol. 26, 475-478 (1988).
13. Casjens, S., van Vugt, R., Stevenson, B., Tilly, K. & Rosa, P. Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochetes. J. Bacteriol. 17, 217-227 (1997).
14. Hinnebush, J. & Barbour, A. G. Linear- and circular-plasmid copy numbers in Borrelia burgdorferi. J. Bacteriol. 174, 5251-5257 (1992).
15. Barbour, A. G., Carter, C. J., Bundoc, V. & Hinnebush, J. The nucleotide sequence of a linear plasmid of Borrelia burgdorferi reveals similarities to those of circular plasmids of other prokaryotes. J. Bacteriol. 178, 6625-6639 (1996).
16. Zuckert, W. R. & Meyer, I. Circular and linear plasmids of Lyme disease spirochetes share extensive homology: characterization of a repeated DNA element. J. Bacteriol. 178, 2287-2298 (1996).
17. Schwan, T. G., Burgdorfer, W. & Garon, C. Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect. Immun. 56, 1831-1836 (1988).
18. Xu, Y., Kodner, C., Coleman, L. & Johnson, R. C. Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31. Infect. Immun. 64, 3870-3876 (1996).
19. Norris, S. I., Howell, J. K., Garza, S. A., Ferdows, M. S. & Barbour, A. G. High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi. Infect. Immun. 63, 2206-2212 (1995).
20. Fleischmann, R. D. et al. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269, 496-512 (1995).
21. Fraser, C. M. et al. The minimal gene complement of Mycoplasma genitalium. Science 270, 397-403 (1995).
22. Bult, C. J. et al. Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii. Science 273, 1058-1072 (1996).
23. Tomb, J.-F. et al. The complete genome sequence of the gastric pathogen Heliocobacter pylori. Nature 388, 539-547 (1997).
24. Klenk, H.-P. et al. The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus. Nature 390, 364-370 (1997).
25. Casjens, S., Ley, H., DeLange, M., Rosa, P. & Huang, W. Linear chromosomes of Lyme disease agent spirochetes; genetic diversity and conservation of gene order. J. Bacteriol. 177, 2769-2780 (1995).
26. Casjens, S. & Huang, W. in Bacterial Genomes: Physical Structure and Analysis (eds de Bruijn, F., Lupski, J. & Weinstock, G. J.) (Chapman and Hall, New York, in the press)
27. Old, I., MacDougall, J., Saint Girons, I. & Davidson, B. Mapping of genes on the linear chromosome of the bacterium Borrelia burgdorferi possible locations for its origin of replication. FEMS Microbiol. Lett. 99, 245-250 (1992).
28. Casjens, S. et al. Telomeres of the linear chromosomes of Lyme disease spirochetes: nucleotide sequence and possible exchange with linear plasmid telomers. Mol. Microbiol. 26, 581-596 (1997).
29. Riley, M. Functions of gene products of Escherichia coli. Microbiol. Rev. 57, 862-952 (1993).
30. Zhang, J., Hardham, J., Barbour, A. & Norris, S. Antigenic variation in Lyme disease Borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89, 275-285 (1997).
31. Dunn, J. J. et al. Complete nucleotide sequence of a circular plasmid from the Lyme disease spirochete, Borrelia burgdorferi. J. Bacteriol. 176, 2706-2717 (1994).
32. Traktman, P. in DNA Replication in Eukaryotic Cells (ed. DePamphilis, M.) 775-798 (Cold Spring Harbor Laboratory Press, NY, 1996).
33. Himmelreich, R. et al. Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae. Nucleic Acids Res. 24, 4420-4449 (1996).
34. Brewer, B. When polymerases collide: replication and the transcriptional organization of the E. coli chromosome. Cell 53, 679-686 (1988).
35. French, S. Consequences of replication fork movement through transcription units in vivo. Science 258, 1362-1365 (1992).
36. Ogasawara, N. & Yoshikawa, H. Genes and their organization in the replication origin region of the bacterial chromosome. Mol. Microbiol. 6, 629-634 (1992).
37. Gazumyan, A., Schwartz, J. I., Liveris, D. & Schwartz, I. Sequence analysis of the ribosomal RNA operon of the Lyme disease spirochete, Borrelia burgdorferi. Gene 146, 57-65 (1994).
38. Ojaimi, C, Davidson, B., Saint Girons, I. & Old, I. Conservation of gene arrangement and an unusual organization of rRNA genes in the linear chromosomes of Lyme disease spirochaetes Borrelia burgdorferi, B. garinii and B. afzelli. Microbiology 140, 2931-2940 (1994).
39. Gln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation. Proc. Natl Acad. Sci. USA 94, 11819-11826 (1997).
40. Ibba, M., Bobo, J. L., Rosa, P. A. & Soll, D. Archaeal-type lysyt-tRNA synthetase in the Lyme disease spirochete Borrelia burgdorferi. Proc. Natl Acad. Sci. USA (in the press).
41. Reizer J, Paulsen, I. T., Reizer, A., Titgemeyer, F. & Saier, M. H. Jr Novel phosphotransferase system genes revealed by bacterial genome analysis: The complete complement of pts genes in Mycoplasma genitalium. Microb. Comp. Genom. 1, 151-164 (1996).
42. Takase, K. et al. Sequencing and characterization of the ntp gene gluster for vacuolar-type Na+-translocating ATPase of Enterococcurs hirae. J. Biol. Chem. 269, 11037-11044 (1994).
43. Sadziene, A., Rosa, P. A., Thompson, P. A., Hogan, D. M. & Barbour, A. G. Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. J. Exp. Med. 176, 799-809 (1992).
44. Brandt, M. E., Riley, B. S., Radolf, J. D. & Norgard, M. V. Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins. Infect. Immun. 58, 983-991 (1990).
45. Hinnebusch, J., Bergstrom, S. & Barbour, A. Cloning and sequence analysis of linear plasmid telomeres of the bacterium Borrelia burgdorferi. Mol. Microbiol. 4, 811-820 (1990).
46. Kitten, T. & Barbour, A. Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii. Proc. Natl Acad. Sci. USA 87, 6077-6081 (1990).
47. Salzberg, S., Delcher, A., Kasif, S. & White, O. Microbial gene identification using interpolated Markov models. Nucleic Acids Res. (in the press).
48. Sonnhammer, E. L. L., Eddy, S. R. & Durbin, R. Pfam: a comprehensive database of protein families based on seed alignments. Proteins 28, 405-420 (1997).
49. Claros, M. G. & von Heijne, G. TopPred II: an improved software for membrane proteins structure predictions. Comput. Appl. Biosci. 10, 685-686 (1994).