The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage

Cancer Research

Volumn 56, Issue 2, 1996, Pages 246-250

  Price, Brendan D ^a   Youmell, Matthew B ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL STRAIN 3T3; CYTOTOXICITY; DNA BINDING; DNA DAMAGE; DNA SYNTHESIS INHIBITION; DRUG EFFECT; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; REPORTER GENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ADENOCARCINOMA; ANDROSTADIENES; ANIMALS; BASE SEQUENCE; BREAST NEOPLASMS; CELL SURVIVAL; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; DNA DAMAGE; DNA, NEOPLASM; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HELA CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RADIATION-SENSITIZING AGENTS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030066023     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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