Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

EMBO Journal

Volumn 16, Issue 20, 1997, Pages 6200-6208

  Herr, Ingrid ^a   Wilhelm, Dagmar ^b,c   Bönler, Thomas ^d   Angel, Peter ^b   Debatin, Klaus Michael ^a,d  

^a Laboratory of Molecular Oncology   (Germany)

^b Deutsches Krebforschungszentrum   (Germany)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

irradiation; Cellular stress; Doxorubicin; JNK SAPKs; Niemann Pick

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; CERAMIDE; COMPLEMENTARY DNA; DOXORUBICIN; FAS ANTIGEN; PROTEIN KINASE; PROTEINASE;

APOPTOSIS; ARTICLE; CANCER THERAPY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GAMMA IRRADIATION; GENE ACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; NIEMANN PICK DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD95; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CERAMIDES; DOXORUBICIN; GAMMA RAYS; HUMANS; JURKAT CELLS; LEUKEMIA, T-CELL; MODELS, BIOLOGICAL; NIEMANN-PICK DISEASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 0030670626     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.20.6200     Document Type: Article

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