Defective E-cadherin/catenin complexes in human cancer

Virchows Archiv

Volumn 439, Issue 6, 2001, Pages 725-751

  Van Aken, E ^a   De Wever, O ^a   Da Rocha, Correia A ^b   Mareel, M ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Cadherin; Cancer; Catenin; Eye; Thyroid

Indexed keywords

ALPHA CATENIN; CATENIN; PLAKOGLOBIN; PROTEIN; PROTEIN CTNNA1; PROTEIN CTNNB1; UNCLASSIFIED DRUG; UVOMORULIN;

ANAPLASTIC CARCINOMA; CARCINOGENESIS; CARCINOMA; EYE DEVELOPMENT; EYE TUMOR; GENE SILENCING; HUMAN; METHYLATION; ONCOGENE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; REVIEW; THYROID ADENOMA; THYROID FOLLICLE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 0035215419     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280100516     Document Type: Review

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215. Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas
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234. Frequent nuclear/cytoplasmic localization of β-catenin without exon 3 mutations in malignant melanoma
235. Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development
236. Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant
237. Reduced expression of α catenin is associated with poor prognosis in colorectal carcinoma
238. Involvement of the tyrosine kinase Fer in cell adhesion
239. Association of the APC gene product with beta-catenin
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246. Role of cadherins in the transendothelial migration of melanoma cells in culture
247. Differential cell adhesion and expression of N-cadherin among retinoblastoma cell lines
248. Molecular analysis of E-cadherin and cadherin-11 in Wilms' tumours
249. E-Cadherin distribution and epithelial basement membrane characteristics of the normal human conjunctiva and cornea
250. Changes in integrin and E-cadherin expression in neoplastic versus normal thyroid tissue
251. Hyperphosphorylation of β-catenin on serine-threonine residues and loss of cell-cell contacts induced by calyculin A and okadaic acid in human epidermal cells
252. The disruption of ad-herens junctions is associated with a decrease of E-cadherin phosphorylation by protein kinase CK2
253. Structural basis of cell-cell adhesion by cadherins
254. Tyrosine phosphorylation of β-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells
255. Dominant negative inhibition of the association between β-catenin and c-erbB-2 by N-terminally deleted β-catenin suppresses the invasion and metastasis of cancer cells
256. Complex cadherin expression in renal cell carcinoma
257. Alterations in expression of cadherin-6 and E-cadherin during kidney development and in renal cell carcinoma
258. Expression of E- and P-cadherin in gastric carcinomas
259. Expression of N-cadherin and α-catenin in astrocytomas and glioblastomas
260. Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line
261. E-cadherin gene alterations are rare events in thyroid tumors
262. Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: Relationship to morphology and invasive capacities
263. E7-transduced human breast epithelial cells show partial differentiation in three-dimensional culture
264. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
265. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
266. The alkyllysophospholipid 1-O-octadecyl-2-O-methyl-glycerophosphocholine induces invasion through episialin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro
267. Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of β-catenin signaling
268. Tumour necrosis factor-α-mediated dyscohesion of epithelial cells is associated with disordered expression of cadherin/β-catenin and disassembly of actin filaments
269. The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis
270. E-cadherin gene promoter hypermethylation in primary human gastric carcinomas
271. Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin
272. E-cadherin is the major mediator of human mel-anocyte adhesion to keratinocytes in vitro
273. Expression of E- and N-cadherin in renal cell carcinomas, in renal cell carcinoma cell lines in vitro and in their xenografts
274. Predominance of beta-catenin mutations and beta-cat-enin dysregulation in sporadic aggressive fibromatosis (des-moid tumor)
275. A possible role of N-cadherin in thalidomide teratogenicity
276. ctn from E-cadherin disrupts strong adhesion
277. Cadherin switching in human prostate cancer progression
278. Effects of PAX2 expression in a human fetal kidney (HEK293) cell line
279. N-cadherin expression in human prostate carcinoma cell lines. An epithelial-mesenchymal transformation mediating adhesion with stromal cells
280. Desmosomal adhesion inhibits invasive behavior
281. TNF-alpha and IL-1beta suppress N-cadherin expression in MC3T3-E1 cells
282. Preoperative chemoradiotherapy alters the expression and prognostic significance of adhesion molecules in Barrett's-associated adenocarcinoma
283. Immunohistochemical analysis of E-cadherin expression in human colorectal tumours
284. ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression
285. The N-cadherin/catenin complex in colon fibroblasts and myofibroblasts
286. Induction of invasion in vivo of α-catenin-positive HCT-8 human colon-cancer cells
287. Dosage requirement and allelic expression of PAX6 during lens placode formation
288. Transition from the noninvasive to the invasive phenotype and loss of α-catenin in human colon cancer cells
289. Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient?
290. The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells
291. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
292. Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells
293. β-Catenin mutations in human prostate cancer
294. Immunohistochemical detection of E-cadherin in differentiated thyroid carcinomas correlates with clinical outcome
295. E-cadherin inactivation in lobular carcinoma in situ of the breast: An early event in tumorigenesis
296. Expression of cadherins and catenins in paired tumor and non-neoplastic primary prostate cultures and corresponding prostatec-tomy specimens
297. Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line
298. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1
299. Soluble 80-kd fragment of cell-CAM 120/80 disrupts cell-cell adhesion
300. Prox1 function is crucial for mouse lens-fibre elongation
301. Β-Catenin: A key mediator of Wnt signaling
302. Regulation of E-cadherin-mediated adhesion by muscarinic acetylcholine receptors in small cell lung carcinoma
303. A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motif
304. Expression of cadherins and catenins in oral epithelial dysplasia and squamous cell carcinoma
305. Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer
306. Transactivation of the multidrug resistance 1 gene by T-cell factor 4/β-catenin complex in early colorectal carcinogenesis
307. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion
308. Adriamycin activates E-cadherin-mediated cell-cell adhesion in human breast cancer cells
309. Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer
310. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
311. Plakoglobin and β-catenin: Protein interactions, regulation and biological roles
312. ctn
313. Regulation of Wnt signaling by Sox proteins: XSox17α/βand XSox3 physically interact with β-catenin
314. Sporadic medulloblastomas contain oncogenic β-catenin mutations