메뉴 건너뛰기




Volumn 83, Issue 1, 2000, Pages 1-5

Recent advances in research on multistage tumorigenesis

Author keywords

Cancer; Oncogenes; Transgenic mice; Tumour suppressor genes

Indexed keywords

ANGIOGENESIS; APOPTOSIS; CANCER RESEARCH; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; METASTASIS; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL; REVIEW; TUMOR CELL; TUMOR SUPPRESSOR GENE; TUMOR VASCULARIZATION;

EID: 0034129118     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1309     Document Type: Review
Times cited : (95)

References (71)
  • 1
    • 0033579163 scopus 로고    scopus 로고
    • Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity
    • Ali IU, Schriml LM and Dean M (1999) Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 91: 1922-1932
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1922-1932
    • Ali, I.U.1    Schriml, L.M.2    Dean, M.3
  • 2
    • 0033604523 scopus 로고    scopus 로고
    • The IGF-1 receptor in cancer research
    • Baserga R (1999) The IGF-1 receptor in cancer research. Exp Cell Res 253: 1-6
    • (1999) Exp Cell Res , vol.253 , pp. 1-6
    • Baserga, R.1
  • 3
    • 0024817936 scopus 로고
    • Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor
    • Becker D, Meier CB and Herlyn M (1989) Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor. Embo J 8: 3685-3691
    • (1989) Embo J , vol.8 , pp. 3685-3691
    • Becker, D.1    Meier, C.B.2    Herlyn, M.3
  • 6
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
    • Brooks PC, Silletti S, von Schalscha TL, Friedlander M and Cheresh DA (1998) Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 92: 391-400
    • (1998) Cell , vol.92 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalscha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 7
    • 0031975738 scopus 로고    scopus 로고
    • The role of beta-catenin in cell adhesion, signal transduction, and cancer
    • Bullions LC and Levine AJ (1998) The role of beta-catenin in cell adhesion, signal transduction, and cancer. Curr Opin Oncol 10: 81-87
    • (1998) Curr Opin Oncol , vol.10 , pp. 81-87
    • Bullions, L.C.1    Levine, A.J.2
  • 9
    • 0031710479 scopus 로고    scopus 로고
    • The INK4a/ARF tumor suppressor: One gene - Two products - Two pathways
    • Chin L, Pomerantz J and DePinho RA (1998) The INK4a/ARF tumor suppressor: one gene - two products - two pathways. Trends Biochem Sci 23: 291-296
    • (1998) Trends Biochem Sci , vol.23 , pp. 291-296
    • Chin, L.1    Pomerantz, J.2    DePinho, R.A.3
  • 10
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW and DePinho RA (1999a). p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97: 527-538
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3    Tam, A.4    Lee, S.L.5    Gottlieb, G.J.6    Greider, C.W.7    DePinho, R.A.8
  • 12
    • 0033079605 scopus 로고    scopus 로고
    • The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
    • Christofori G and Semb H (1999) The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci 24: 73-76
    • (1999) Trends Biochem Sci , vol.24 , pp. 73-76
    • Christofori, G.1    Semb, H.2
  • 13
    • 0028356419 scopus 로고
    • A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis
    • Christofori G, Naik P and Hanahan D (1994) A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 369: 414-418
    • (1994) Nature , vol.369 , pp. 414-418
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 17
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA and Bouck N (1994) Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265: 1582-1584
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 18
    • 0033590179 scopus 로고    scopus 로고
    • DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis
    • Dasika GK, Lin SC, Zhao S, Sung P, Tomkinson A and Lee EY (1999) DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene 18: 7883-7899
    • (1999) Oncogene , vol.18 , pp. 7883-7899
    • Dasika, G.K.1    Lin, S.C.2    Zhao, S.3    Sung, P.4    Tomkinson, A.5    Lee, E.Y.6
  • 19
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • Downward J. (1998) Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10, 262-267
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 262-267
    • Downward, J.1
  • 20
    • 0033581835 scopus 로고    scopus 로고
    • Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability
    • Duval A, lacopetta B, Ranzani GN, Lothe RA, Thomas G and Hamelin R. (1999) Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability. Oncogene 18: 6806-6809
    • (1999) Oncogene , vol.18 , pp. 6806-6809
    • Duval, A.1    Lacopetta, B.2    Ranzani, G.N.3    Lothe, R.A.4    Thomas, G.5    Hamelin, R.6
  • 21
    • 0032941717 scopus 로고    scopus 로고
    • Regulation of LEF-1/TCF transcription factors by Wnt and other signals
    • Eastman Q and Grosschedl R (1999) Regulation of LEF-1/TCF transcription factors by Wnt and other signals. Curr Opin Cell Biol 11: 233-240
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 233-240
    • Eastman, Q.1    Grosschedl, R.2
  • 22
    • 0029818753 scopus 로고    scopus 로고
    • Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
    • Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA and Hennighausen L (1996) Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 273: 1384-1386
    • (1996) Science , vol.273 , pp. 1384-1386
    • Ewald, D.1    Li, M.2    Efrat, S.3    Auer, G.4    Wall, R.J.5    Furth, P.A.6    Hennighausen, L.7
  • 23
    • 0002799842 scopus 로고    scopus 로고
    • Growth factors
    • Holland JF, Bast RC, Morton DL, Frei E, Kufe DW and Weichselbaum RR (eds). Williams and Wilkins: Baltimore, MD
    • Fedi P, Tronick SR and Aaronson SA (1997) Growth factors. In: Cancer Medicine, Holland JF, Bast RC, Morton DL, Frei E, Kufe DW and Weichselbaum RR (eds) pp 41-64. Williams and Wilkins: Baltimore, MD
    • (1997) Cancer Medicine , pp. 41-64
    • Fedi, P.1    Tronick, S.R.2    Aaronson, S.A.3
  • 24
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • Felsher DW and Bishop JM (1999) Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 4: 199-207
    • (1999) Mol Cell , vol.4 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 25
    • 0032852528 scopus 로고    scopus 로고
    • Molecular and biological properties of vascular endothelial growth factor
    • Ferrara N (1999) Molecular and biological properties of vascular endothelial growth factor. J Mol Med 77: 527-543
    • (1999) J Mol Med , vol.77 , pp. 527-543
    • Ferrara, N.1
  • 26
    • 0032710319 scopus 로고    scopus 로고
    • Clinical applications of angiogenic growth factors and their inhibitors
    • Ferrara N and Alitalo K (1999) Clinical applications of angiogenic growth factors and their inhibitors. Nat Med 5: 1359-1364
    • (1999) Nat Med , vol.5 , pp. 1359-1364
    • Ferrara, N.1    Alitalo, K.2
  • 28
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J (1990) What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 29
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 33
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D and Folkman J (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 34
    • 0028263811 scopus 로고
    • Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington EA, Bennett MR, Fanidi A and Evan GI (1994) c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. Embo J 13: 3286-3295
    • (1994) Embo J , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 36
    • 0032731581 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes in cancer
    • Herman JG (1999) Hypermethylation of tumor suppressor genes in cancer. Semin Cancer Biol 9: 359-367
    • (1999) Semin Cancer Biol , vol.9 , pp. 359-367
    • Herman, J.G.1
  • 37
    • 0033004686 scopus 로고    scopus 로고
    • Role of telomerase in cellular proliferation and cancer
    • Holt SE and Shay JW (1999) Role of telomerase in cellular proliferation and cancer. J Cell Physiol 180: 10-18
    • (1999) J Cell Physiol , vol.180 , pp. 10-18
    • Holt, S.E.1    Shay, J.W.2
  • 38
    • 0030667376 scopus 로고    scopus 로고
    • Requirement for the CD95 receptor-ligand pathway in c-Myc induced apoptosis
    • Hueber AO, Zornig M, Lyon D, Suda T, Nagata S and Evan GI (1997) Requirement for the CD95 receptor-ligand pathway in c-Myc induced apoptosis. Science 278: 1305-1309
    • (1997) Science , vol.278 , pp. 1305-1309
    • Hueber, A.O.1    Zornig, M.2    Lyon, D.3    Suda, T.4    Nagata, S.5    Evan, G.I.6
  • 40
    • 0038668000 scopus 로고    scopus 로고
    • Escaping cell death: Survival proteins in cancer
    • Jaattela M (1999) Escaping cell death: survival proteins in cancer. Exp Cell Res 248: 30-43
    • (1999) Exp Cell Res , vol.248 , pp. 30-43
    • Jaattela, M.1
  • 41
  • 42
    • 0033605145 scopus 로고    scopus 로고
    • p53-and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J, Broccoli D, Dai Y, Hardy S and de Lange T (1999) p53-and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science 283: 1321-1325
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 43
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW and Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 46
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW and Vogelstein B (1998) Genetic instabilities in human cancers. Nature 396: 643-649
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 47
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M and Lowe SW (1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 12: 3008-3019
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 50
    • 0033001621 scopus 로고    scopus 로고
    • Reversible activation of c-Myc in skin: Induction of a complex neoplastic phenotype by a single oncogenic lesion
    • Pelengaris S, Littlewood T, Khan M, Elia G and Evan G (1999) Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol Cell 3: 565-577
    • (1999) Mol Cell , vol.3 , pp. 565-577
    • Pelengaris, S.1    Littlewood, T.2    Khan, M.3    Elia, G.4    Evan, G.5
  • 51
    • 0030948865 scopus 로고    scopus 로고
    • Mutations predisposing to hereditary nonpolyposis colorectal cancer
    • Peltomaki P and de la Chapelle A (1997) Mutations predisposing to hereditary nonpolyposis colorectal cancer. Adv Cancer Res 71: 93-119
    • (1997) Adv Cancer Res , vol.71 , pp. 93-119
    • Peltomaki, P.1    De La Chapelle, A.2
  • 52
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dabl U, Semb H and Christofori G (1998) A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392: 190-193
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dabl, U.3    Semb, H.4    Christofori, G.5
  • 53
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • Polakis P (1997) The adenomatous polyposis coli (APC) tumor suppressor. Biochim Biophys Acta 1332: F127-147
    • (1997) Biochim Biophys Acta , vol.1332
    • Polakis, P.1
  • 54
    • 0031955355 scopus 로고    scopus 로고
    • Metalloproteases and urokinase in angiogenesis and tumor progression
    • Rabbani SA (1998) Metalloproteases and urokinase in angiogenesis and tumor progression. In Vivo 12: 135-142
    • (1998) In Vivo , vol.12 , pp. 135-142
    • Rabbani, S.A.1
  • 58
    • 0344417114 scopus 로고    scopus 로고
    • Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype
    • Schwartz S Jr, Yamamoto H, Navarro M, Maestro M, Reventos J and Perucho M (1999) Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res 59: 2995-3002
    • (1999) Cancer Res , vol.59 , pp. 2995-3002
    • Schwartz S., Jr.1    Yamamoto, H.2    Navarro, M.3    Maestro, M.4    Reventos, J.5    Perucho, M.6
  • 59
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15: 551-578
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 60
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p161INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D and Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p161INK4a. Cell 88: 593-602
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 61
    • 0032191393 scopus 로고    scopus 로고
    • Tumor surveillance via the ARF-p53 pathway
    • Sherr CJ (1998) Tumor surveillance via the ARF-p53 pathway. Genes Dev 12: 2984-2991
    • (1998) Genes Dev , vol.12 , pp. 2984-2991
    • Sherr, C.J.1
  • 65
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O and McCormick F (1999) Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 66
    • 0032739329 scopus 로고    scopus 로고
    • CpG island methylator phenotypes in aging and cancer
    • Toyota M and Issa JP (1999) CpG island methylator phenotypes in aging and cancer. Semin Cancer Biol 9: 349-357
    • (1999) Semin Cancer Biol , vol.9 , pp. 349-357
    • Toyota, M.1    Issa, J.P.2
  • 68
    • 0023942517 scopus 로고
    • Growth factor receptor tyrosine kinases
    • Yarden Y and Ullrich A (1988) Growth factor receptor tyrosine kinases. Annu Rev Biochem 57: 443-478
    • (1988) Annu Rev Biochem , vol.57 , pp. 443-478
    • Yarden, Y.1    Ullrich, A.2
  • 69
    • 0033568462 scopus 로고    scopus 로고
    • Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
    • Zhang X, Mar V, Zhou W, Harrington L and Robinson MO (1999) Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev 13: 2388-2399
    • (1999) Genes Dev , vol.13 , pp. 2388-2399
    • Zhang, X.1    Mar, V.2    Zhou, W.3    Harrington, L.4    Robinson, M.O.5
  • 70
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of human fibroblasts induced by oncogenic Raf
    • Zhu J, Woods D, McMahon M and Bishop JM (1998) Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev 12: 2997-3007
    • (1998) Genes Dev , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.