Regulation of Wnt signaling by Sox proteins: XSox17α/β and XSox3 physically interact with β-catenin

Molecular Cell

Volumn 4, Issue 4, 1999, Pages 487-498

  Zorn, Aaron M ^a   Barish, Grant D ^c   Williams, Bart O ^c   Lavender, Paul ^a,b   Klymkowsky, Michael W ^d   Varmus, Harold E ^c  

^a Wellcome Trust/CRCICDB   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; LUCIFERASE; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; XSOX 17B; XSOX 3;

ANIMAL CELL; ARTICLE; BINDING SITE; EMBRYO; ENZYME INHIBITION; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALIA; ARMADILLO;

EID: 0033213619     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80200-2     Document Type: Article

References (61)

1. Aberle, H., Bauer, A., Stappert, J., Kispert, A., and Kemler, R. (1997). β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804.
2. Behrens, J., von Kries, J.P., Kühl, M., Bruhn, L., Wedlich, D.R.G., and Birchmeier, W. (1996). Functional interaction of β-catenin with the transcription factor LEF-1. Nature 382, 638-642.
3. Bhanot, P., Brink, M., Samos, C.H., Hsieh, J.C., Wang, Y., Macke, J.P., Andrew, D., Nathans, J., and Nusse, R. (1996). A new member of the frizzled family from Drosophila functions as a wingless receptor. Nature 382, 225-230.
4. Botquin, V., Hess, H., Fuhrmann, G., Anastassiadis, C., Gross, M.K., Vriend, G., and Scholer, H.R. (1998). New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and sox-2. Genes Dev. 12, 2073-2090.
5. Brannon, M., Gomperts, M., Sumoy, L., Moon, R.T., and Kimelman, D. (1997). A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev. 11, 2359-2370.
6. Bruhn, L., Munnerlyn A., and Grosschedl, R. (1997). ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRα enhancer function. Genes Dev. 11, 640-653.
7. Cadigan, K.M., and Nusse, R. (1997). Wnt signaling: A common theme in animal development. Genes Dev. 11, 3286-3305.
8. Carnac, G., Kodjabachian, L., Gurdon, J.B., and Lemaire, P. (1996). The homeobox gene siamois is a target of the Wnt dorsalisation pathway and triggers organizer activity in the absence of mesoderm. Development 122, 3055-3065.
9. Clevers, H., and van de Wetering, M. (1997). TCF/LEF factors earn their wings. Trends Genet. 13, 485-489.
10. Cook, D., Fry, M.J., Hughes, K., Sumathipala, R., Woodgett, J.R., and Dale, T.C. (1996). Wingless inactivates glycogen synthase kinase-3 via an intracellular signaling pathway which involves protein kinase C. EMBO J. 15, 4526-4536.
11. Funayama, N., Fagotto, F., McCrea, P., and Gumbiner, B.M. (1995). Embryonic axis induction by the armadillo repeat domain of β-catenin: Evidence for intracellular signaling. J. Cell Biol. 128, 959-968.
12. Giese, K., and Grosscheld, R. (1993). LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites. EMBO J. 12, 4667-4676.
13. Graff, J.M., Thies, R.S., Song, J.J., Celeste, A.J., and Melton, D.A. (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.
14. Gubbay, J., Collignon, J., Koopman, P., Capel, B., Economou, A., Muensterberg, A., Vivian, N., Goodfellow, P., and Lovell-Badge, R. (1990). A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346, 245-249.
15. Gurdon, J.B. (1977). Methods for nuclear transplantation in amphibia. Methods Cell Biol. 16, 125-139.
16. He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E., and Dawid, I.B. (1995). Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374, 617-622.
17. Heasman, J. (1997). Patterning the Xenopus blastula. Development 124, 4179-4191.
18. Hosking, B.M., Muscat, G.E.O., Koopman, P., Dowhan, D.H., and Dunn, T.L. (1995). Trans-activation and DNA-binding properties of the transcription factor, sox-18. Nucleic Acids Res. 23, 2626-2628.
19. Hsu, S.-C., Galceran, J., and Grosschedl, R. (1998). Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin. Mol. Cell Biol. 18, 4807-4818.
20. Huber, O., Korn, R., McLaughlin, J., Oshugi, M., Herrmann, B.G., and Kemler, R. (1996). Nuclear localization of β-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-10.
21. Hudson, C., Clements, D., Friday, R.V., Scott, D., and Woodland, H.R. (1997). XSox17α and -β mediate endoderm formation in Xenopus. Cell 91, 397-405.
22. Kamachi, Y., Sockanathan, S., Lui., Q., Breitman, M., Lovell-Badge, R., and Kondoh, H. (1995). Involvement of sox proteins in lens-specific activation of crystallin genes. EMBO J. 14, 3510-3519.
23. Kamachi, Y., Cheah, K.S.E., and Kondoh, H. (1998). Mechanism of regulatory target selection by the sox high-mobility-group domain proteins as revealed by comparison of sox1/2/3 and sox9. Mol. Cell. Biol. 19, 107-120.
24. Kanai, Y., Kania-Azuma, M., Noce, T., Saido, T.C., Shiroishi, T., Hayashi, Y., and Yazaki, K. (1996). Identification of two sox17 messenger RNA isoforms, with and without the high mobility group box region and their differential expression in mouse spermatogenesis. J. Cell Biol. 133, 667-681.
25. Kao, K., and Elinson, R.P. (1988). The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos. Dev. Biol. 127, 64-77.
26. Kitajewski, J., Mason, J., and Varmus, H. (1992). Interaction of Wnt-1 proteins with the binding protein BiP. Mol. Cell. Biol. 12, 784-790.
27. Klymkowsky, M.W. (1997). Minireviews, minidogmas and mythinformation. BioEssays 19, 537-539.
28. -/- colon carcinoma. Science 275, 1784-1787.
29. Laurent, M.N., Blitz, I.L., Hashimoto, C., Rothbächer, U., and Cho, K.W.-Y. (1997). The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer. Development 124, 4905-4916.
30. Lemaire, P., Garrett, N., and Gurdon, J.B. (1995). Expression cloning of siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.
31. Levanon, D., Goldstein, R.E., Bernstein, Y., Tang, H., Goldenberg, D., Stifani, S., Paroush, Z., and Groner, Y. (1998). Transcriptional repression by AML1 and LEF-1 in mediated by the TLE/groucho corepressors. Proc. Natl. Acad. Sci. USA 95, 11590-11595.
32. Li, J.M., Datto, M.B., Shen, X., Hu, P.P., Yu, Y., and Wang, X.F. (1998). Sp1, but not Sp3, functions to mediate promoter activation by TGF-β through canonical Sp1 binding sites. Nucleic Acids Res. 26, 2449-2456.
33. Lin, R., Thompson, S., and Priess, J.R. (1997). Pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. Elegans embryos. Cell 83, 599-609.
34. Lovell-Badge, R., and Robertson, R. (1990). XY female mice resulting from a heritable mutation in the primary testes determining gene, Tdy. Development 109, 635-646.
35. McKendry, R., Hsu, S.-C., Harland, R.M., and Grosschedl, R. (1997). LEF-1/TCF proteins mediate Wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev. Biol. 192, 420-431.
36. McMahon, A.P., and Moon, R.T. (1989). Ectopic expression of the proto-oncogene int-1 in Xenopus embryos lead to duplication of the embryonic axis. Cell 58, 1075-1084.
37. Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Marduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O., and Clevers, H. (1996). XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell 86, 391-399.
38. Moon, R.T., and Kimelman, D. (1998). From cortical rotation to organizer gene expression: Towards a molecular explanation of axis specification in Xenopus. BioEssays 20, 536-545.
39. Moon, R.T., Brown, J.D., and Torres, M. (1997). WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 13, 157-162.
40. Nambu, P.A., and Nambu, J.R. (1996). The Drosophila fish-hook gene encodes a HMG domain protein essential for segmentation and CNS development. Development 122, 3467-3475.
41. Penzel, R., Oschwald, R., Chen, Y., Tacke, L., and Grunz, H. (1997). Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis. Int. J. Dev. Biol. 41, 667-677.
42. Pevny, L.H., and Lovell-Badge, R. (1997). Sox genes find their feet. Curr. Opin. Genet. Dev. 7, 338-344.
43. Reichardt, H.M., Kaestner, K.H., Tuckermann, J., Kretz, O., Wessely, O., Bock, R., Gass, P., Schmid, W., Herrlich, P., Angel, P., and Schütz, G. (1998). DNA binding of glucocorticoid receptor is not essential for survival. Cell 93, 531-541.
44. Rocheleau, C.E., Downs, W.D., Lin, R., Wittmann, C., Bei, Y., Cha, Y.-H., Ali, M., Priess, J.R., and Mello, C.C. (1997). Wnt signaling and an APC-related gene specify endoderm in early C. Elegans embryos. Cell 90, 707-716.
45. Roose, J., Molenaar, M., Peterson, J., Hurenkamp, J., Brantjes, H., Moerer, P., van de Wetering, M., Destree, O., and Clevers, H. (1998). The Xenopus Wnt effector XTcf-3 interacts with groucho-related transcriptional repressors. Nature 395, 608-612.
46. Russell, S.R., Sanchez-Soriano, N., Wright, C.R., and Ashburner, M. (1996). The dichaete gene of Drosophila melanogaster encodes a sox-domain protein required for embryonic segmentation. Development 122, 3669-3676.
47. Schillam, M.W., Oosterwegel, M.A., Moerer, P., Ya, J., De Boer, P.A.J., van de Wetering, M., Verbeek, S., Lamers, W.H., Kruisbeek, A.M., Cumano, A., and Clevers, H. (1996). Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking sox-4. Nature 380, 711-714.
48. Schneider, S., Steinbeisser, H., Warga, R.M., and Hausen. P. (1996). β-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos. Mech. Dev. 57, 191-198.
49. Smith, W.C., and Harland, R.M. (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765.
50. Smith, W.C., McKendry, R., Ribisi, S., and Harland, R.M. (1995). A nodal-related gene defines a physical and functional domain within the organizer. Cell 82, 37-47.
51. Thomsen, G.H., and Melton, D.A. (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.
52. van de Wetering, M., Oosterwegel, M., van Norren, K., and Clevers, H. (1993). Sox-4, an sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J. 12, 3847-3854.
53. van de Wetering, M., Cavallo, R., Dooijes, D., van Beest, M., van Es, J., Loureiro, J., Ypma, A., Hursh, D., Jones, T., Bejsovec, A., et al. (1997). Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88, 789-799.
54. Wagner, T., Wirth, J., Meyer, J., Zabel, B., Held, M., Zimmer, J., Pasantes, J., Bricareli, F.D., Keutel, J., Hurster, E., et al. (1994). Autosomal sex reversal and campomelic dysplasia are caused by mutations in an SRY related gene sox9. Cell 79, 1111-1120.
55. Waltzer, L., and Bienz, M. (1998). Drosophila CBP represses the transcription factor TCF to antagonize wingless signaling. Nature 395, 521-525.
56. Wegner, M. (1999) From head to toes: The multiple facets of sox proteins. Nucleic Acids Res. 27, 1409-1420.
57. Wilbert, K., and Nusse, R. (1998). β-catenin: A key mediator of Wnt signaling. Curr. Opin. Gen. Dev. 8, 95-102.
58. Yanagawa, S., van Leeuwen, F., Wodorz, A., Klingensmith, J., and Nusse, R. (1995). The dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev. 9, 1087-1097.
59. Yost, C., Torres, M., Miller, J.R., Huang, E., Kimelman, D., and Moon, R.T. (1996). The axis-inducing activity, stability and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev. 10, 1443-1454.
60. Yuan, H., Corbi, N., Basilico, C., and Dailey, L. (1995). Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of sox-2 and Oct-3. Genes Dev. 9, 2935-2645.
61. Zorn, A.M., and Krieg, P.A. (1997). The KH domain protein encoded by quaking functions as a dimer and is essential for notochord development in Xenopus embryos. Genes Dev. 11, 2176-2190.