Altered cadherin and catenin complexes in the Barrett's esophagus- dysplasia-adenocarcinoma sequence: Correlation with disease progression and dedifferentiation

American Journal of Pathology

Volumn 152, Issue 1, 1998, Pages 135-144

  Bailey, Tracey ^a   Biddlestone, Leigh ^b   Shepherd, Neil ^b   Barr, Hugh ^b   Warner, Philip ^a   Jankowski, Janusz ^c  

^a CRANFIELD UNIVERSITY   (United Kingdom)

^b GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

^c QUEEN ELIZABETH II HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATENIN; UVOMORULIN;

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CONTROLLED STUDY; DISEASE COURSE; EPITHELIUM DYSPLASIA; ESOPHAGUS CARCINOMA; ESOPHAGUS MUCOSA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS EPITHELIUM; TISSUE DIFFERENTIATION; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION;

ADENOCARCINOMA; ADULT; AGED; ALPHA CATENIN; BARRETT ESOPHAGUS; BETA CATENIN; BLOTTING, WESTERN; CADHERINS; CELL NUCLEUS; CYTOSKELETAL PROTEINS; DESMOPLAKINS; DISEASE PROGRESSION; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; TISSUE DISTRIBUTION; TRANS-ACTIVATORS;

EID: 0031984835     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Blot WJ: Esophageal cancer trends and risk factors. Semin Oncol 1994, 21:403-410
2. Dent J, Bremner CG, Collen MJ, Haggitt RC, Spechler SJ: Working party report to the world congresses of gastroenterology, Sydney 1990. Gastroenterol Hepatol 1991, 6:1-22
3. Haggitt RC, Dean PJ: Adenocarcinoma in Barrett's esophagus. Barrett's Esophagus: Pathophysiology, Diagnosis and Management. Edited by SJ Spechler, R. Goyal New York, Elsevier, 1985, pp 53-166
4. Vanderburgh A, Dees J, Hop WCJ, Van Blankenstein M: Oesophageal cancer is an uncommon cause of death in patients with Barrett's oesophagus. Gut 1996, 39:5-8
5. Haggitt RC: Barrett's esophagus, dysplasia, and adenocarcinoma. Hum Pathol 1994, 25:982-993
6. Albelda SM: Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab Invest 1993, 68:4-17
7. Takeichi M: Cadherin cell adhesion receptors as a morphogenetic regulator Science 1991, 251:1451-1455
8. Tsukita S: Submembranous junctional plaque proteins include potential tumor suppressor proteins. J Cell Biol 1993, 123:1049-1053
9. McNeill H, Ozawa M, Kemler R, Nelson WJ: Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell 1990, 62:309-316
10. Nagafuchi A, Shirayochi Y, Okazaki K, Yasuda K, Takeichi M: Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA Nature 1987, 329:341-343
11. Nose A, Nagafuchi A, Takeichi M: Isolation of placental cadherin cDNA: identification ot a novel gene family of cell-cell adhesion molecules. EMBO J 1987, 6:3655-3661
12. Nagafuchi A, Takeichi M: Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J 1988, 7:3679-3684
13. Ozawa M, Ringwald M, Kemler R: Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci USA 1990, 87:4246-4250
14. Eidelman S, Damsky CH, Wheelock MJ, Damianov I: Expression of the cell-cell adhesion glycoprotein cell-CAM 120/80 in normal human tissues and tumors. Am J Pathol 1989, 135:101-110
15. Hyafil F, Morello D, Babinet C, Jacob F: A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos. Cell 1980, 21:927-934
16. Kemler R, Babinet C, Eisen H, Jacob F: Surface antigen in early differentiation. Proc Nat Acad Sci USA 1977, 74:4449-4452
17. Behrens J, Mareel MM, Van Roy FM, Birchmeier W: Dissecting tumor cell invasion: epithelial cells aquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 1989, 108: 2435-2447
18. Vleminckx K, Vakaet L, Mareel M, Fiers W, Van Roy F: Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991, 66:107-119
19. Mareel M, Vleminckx K, Vermeulen S. Bracke M, Van Roy F: E-cadherin expression: a counterbalance for cancer cell invasion. Bull Cancer 1992, 79:347-355
20. Dorudi S, Sheffield JP, Poulsom R, Northover JMA, Hart IR: E-cadherin expression in colorectal cancer: an immunocytochemical and in situ hybridization study. Am J Pathol 1993, 142:981-986
21. Dorudi S, Hanby AM, Poulsom R, Northover J, Hart I: Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. Br J Cancer 1995, 71:614-616
22. Bringuier PP, Umbas R, Schaafsma HE, Karthaus HFM, DeBruyne FMJ, Schalken JA: Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res 1993, 53:3241-3245
23. Yonemura Y, Ninomiya I, Kaji M, Sugiyama K, Fujimura T, Tsuchihara K, Kawamura T, Miyazaki I, Endou Y, Tanaka M, Sasaki T: Decreased E-cadherin expression correlates with poor survival in patients with gastric cancer Anal Cell Pathol 1995, 8:177-190
24. Gabbert HE, Mueller W, Schneiders A, Meier S, Moll R, Birchmeier W: Prognostic value of E-cadherin expression in 413 gastric carcinomas, Int J Cancer 1996, 69:184-189
25. Bongiorno PF, Al-Kasspooles M, Lee SW, Rachwal WJ, Moore JH, Whyte RI, Orringer MB, Beer DG: E-cadherin expression in primary and metastatic thoracic neoplasms and in Barren's oesophagus. Br J Cancer 1995, 71:166-172
26. Miyata M, Shiozaki H, Iihara K, Shimaya K, Oka H, Kadowaki T, Inoue M, Tamura S, Takeichi M, Mori T: Relationship between E-cadherin expression and lymph node metastasis in human esophageal cancer. Int J Oncol 1994; 4:61-65
27. Jankowski JA, Newham, PM, Kandemir O, Hirano S, Takeichi M, Pignatelli M: Differential expression of E-cadherin in normal, metaplastic and dysplastic oesophageal mucosa: a putative biomarker. Int J Oncol 1994, 4:441-448
28. Oyama T, Kanai Y, Ochiai A, Akimoto S, Oda T, Yanagihara K, Nagafuchi A, Tsukita S, Shibamoto S, Ito F, Takeichi M, Matsuda H, Hirohashi S: A truncated beta catenin disrupts the interaction between E-cadherin and alpha catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines. Cancer Res 1994, 54:6282-6287
29. Shimoyama Y, Nagafuchi A, Fujita S, Gotoh M, Takeichi M, Tsukita S, Hirohashi S: Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha catenin expression in reduced cell-cell adhesiveness. Cancer Res 1992, 52:5770-5774
30. Kadowaki T, Shiozaki H, Inoue M, Tamura S, Oka H, Doki Y, Iihara K, Matsui S, Iwazawa T, Nagafuchi A, Tsukita S, Mon T: E-cadherin and alpha-catenin expression in human esophageal cancer. Cancer Res 1994, 54:291-296
31. Shiozaki H, Iihara K, Oka H, Kadowaki T, Matsui S, Gofuku J, Inoue M, Nagafuchi A, Tsukita S, Mori T: Immunohistochemical detection of alpha catenin expression in human cancers. Am J Pathol 1994, 144:667-674
32. Takayama T, Shiozaki H, Shibamoto S, Oka H, Kimura Y, Tamura S, Inoue M, Monden T, Ito F, Monden M: β-Catenin expression in human cancers. Am J Pathol 1996, 148:39-46
33. Candidus S. Bischoff P. Becker K-F, Hofler H: No evidence for mutations in the alpha-catenin and beta-catenin genes in human gastric and breast carcinomas. Cancer Res 1996, 56:49-52
34. Jankowski JAZ, Bedford FK: Assessing proteins and nucleic acids quantitatively and qualitatively by gel fractionation and related techniques. Clinical Gene Analysis and Manipulation. Edited by JAZ Jankowski, JM Polak. Cambridge, UK, Cambridge University Press, 1996, pp 167-204
35. Swami S, Kumble S, Triadafilopoulos G: E-cadherin expression in gastroesophageal reflux disease. Barrett's esophagus and esophageal adenocarcinoma: an immunohistochemical and immunoblot study, Am J Gastroenterol 1995, 90:1808-1813
36. Pignatelli M: E-cadherin: a biological marker of tumor differentiation. J Pathol 1993, 171:81-87
37. Schipper JH, Frixen UH, Behrens J, Linger A, Jahnke K, Birchmeier W: E-cadherin expression in squamous cell carcinomas of the head and neck: inverse correlation with tumor dedifferentation and lymph node metastasis. Cancer Res 1991, 51:6328-6337
38. Takeichi M: The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development 1988, 102:639-655
39. Palacios J, Benito N, Pizarro A, Suarez A, Espada J, Cano A, Gamallo C: Anomalous expression of P-cadherin in breast carcinoma: correlation with E-cadherin expression and pathological features. Am J Pathol 1995, 146:605-612
40. Bussemakers MJG, Giroldi LA, van Bokhoven A, Schalken JA: Transcriptional regulation of the human E-cadherin gene in prostate cancer cell lines: characterization of the human E-cadherin gene promotor. Biochem Biophys Res Commun 1994, 203:1284-1290
41. Hinck L, Nathke IS, Papkoff J, Nelson WJ: Dynamics of cadherin/ catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol 1994, 125:1327-1340
42. Su L-K, Vogelstein B, Kinzler KW: Association of the APC tumor suppressor protein with catenins, Science 1993, 262:1734-1737
43. Rubinfeld B, Souza B, Albert I, Muller O, Chamberlain SH, Masiarz FR, Munemitsu S, Polakis P: Association of the APC gene product with beta catenin. Science 1993, 262:1731-1734
44. Hoschuetzky H, Aberle H, Kemler R: Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol 1994, 127:1375-1380
45. Shimazui T, Schalken JA, Giroldi LA, Jansen CFJ, Akaza H, Koiso K, DeBruyne, MJ, Bringuier PP: Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-cateninsand p120cas)in bladder tumors. Cancer Res 1996, 56:4154-4158
46. Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W: Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996, 382:638-642
47. Molenaar M, Van de Wetering M, Oosterwegel J, Peterson-Maduro S, Godsave S, Korinek V, Roose J, Destree O. Clevers H: Xtcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996, 86:391-399
48. Morin PJ, Sparks AB, Korinek V, Barker H, Clevers H, Vogelstein B, Kinzler KW: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275:1787-1790