-
1
-
-
0033119367
-
Genetic control of programmed cell death in the nematode Caenorhabditis elegans
-
(1999)
Cancer Res.
, vol.59
, pp. 1701-1706
-
-
Horvitz, H.R.1
-
2
-
-
0028929328
-
Mechanisms and genes of cellular suicide
-
(1995)
Science
, vol.267
, pp. 1445-1449
-
-
Steller, H.1
-
4
-
-
0034644508
-
Insights into Programmed cell death through structural biology
-
(2000)
Cell
, vol.103
, pp. 273-282
-
-
Fesik, S.W.1
-
5
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
13
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/Caspase-9 complex initiates an apoptotic protease cascade
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
-
17
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31199-31203
-
-
Jiang, X.1
Wang, X.2
-
23
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO mediates opposing effects on caspase activity and apoptosis
-
(2001)
Nature
, vol.409
, pp. 112-116
-
-
Srinivasula, S.M.1
-
26
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
-
28
-
-
0033592470
-
NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
-
(1999)
Nature
, vol.401
, pp. 818-822
-
-
Sun, C.1
-
29
-
-
0034721940
-
NMR structure and mutagenesis of the third BIR domain of the inhibitor of apoptosis protein XIAP
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33777-33781
-
-
Sun, C.1
-
30
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation during apoptosis
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Wang, X.4
-
31
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
-
32
-
-
0034680876
-
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36152-36157
-
-
Srinivasula, S.M.1
-
34
-
-
0033231614
-
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator
-
(1999)
Mol. Cell
, vol.4
, pp. 757-769
-
-
Kanuka, H.1
-
36
-
-
0033193863
-
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 272-279
-
-
Rodriguez, A.1
-
45
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
-
47
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
-
49
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
-
52
-
-
0033542482
-
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
-
(1999)
Nature
, vol.399
, pp. 547-555
-
-
Qin, H.1
-
60
-
-
0032580153
-
NMR structure and mutagenesis of the FADD (Mort1) death-effector domain
-
(1998)
Nature
, vol.392
, pp. 941-945
-
-
Eberstadt, M.1
-
61
-
-
17144438370
-
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1796-1803
-
-
Tamm, I.1
-
64
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
-
65
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
-
67
-
-
0034644712
-
XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31733-31738
-
-
Datta, R.1
-
68
-
-
0034095571
-
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
-
(2000)
Chem. Biol.
, vol.7
, pp. 423-432
-
-
Wei, Y.1
-
70
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
-
71
-
-
0035831022
-
Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
-
(2001)
Cell
, vol.104
, pp. 781-790
-
-
Huang, Y.1
-
72
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
-
73
-
-
0028817947
-
Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
-
(1995)
Science
, vol.269
, pp. 1885-1888
-
-
Bump, N.J.1
-
74
-
-
0032575309
-
Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex
-
(1998)
Biochemistry
, vol.37
, pp. 10757-10765
-
-
Zhou, Q.1
-
75
-
-
0035932465
-
Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex
-
(2001)
Nature
, vol.410
, pp. 494-497
-
-
Xu, G.1
-
78
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
-
81
-
-
0034640102
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
-
(2000)
Cell
, vol.101
, pp. 389-399
-
-
Li, K.1
-
84
-
-
0034695914
-
Debcl, a aroapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery
-
(2000)
J. Cell Biol.
, vol.148
, pp. 703-714
-
-
Colussi, P.A.1
-
85
-
-
0034282917
-
Drosophila Pro-apoptotic Bcl-2/Bax homologue reveals evolutionary conservation of dell death mechanisms
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27303-27306
-
-
Zhang, H.1
-
86
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
|