The BIR motifs mediate dominant interference and oligomerization of inhibitor of apoptosis Op-IAP

Molecular and Cellular Biology

Volumn 20, Issue 5, 2000, Pages 1877-1885

  Hozak, Rebecca R ^a   Manji, Gulam A ^a   Friesen, Paul D ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE INHIBITOR; INHIBITOR OF APOPTOSIS PROTEIN; PEPTIDE FRAGMENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; LEPIDOPTERA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN POLYMERIZATION; PROTEIN SECONDARY STRUCTURE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; APOPTOSIS; CELL LINE; DIMERIZATION; GENE EXPRESSION REGULATION; INHIBITOR OF APOPTOSIS PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; VIRAL PROTEINS;

EID: 0033961282     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.5.1877-1885.2000     Document Type: Article

References (50)

1. Adida, C., D. Berrebi, M. Peuchmaur, M. Reyes-Mugica, and D. C. Altieri. 1998. Anti-apoptotis gene, survivin, and prognosis of neuroblastoma. Lancet 351:882-883.
2. Ambrosini, G., C. Adida, and D. C. Altieri. 1997. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3:917-921.
3. Bergmann, A., J. Agapite, and H. Steller. 1998. Mechanisms and control of programmed cell death in invertebrates. Oncogene 17:3215-3223.
4. Bertin, J., S. M. Mendrysa, D. J. LaCount, S. Gaur, J. F. Krebs, R. C. Armstrong, K. J. Tomaselli, and P. D. Friesen. 1996. Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease. J. Virol. 70:6251-6259.
5. Birnbaum, M. J., R. J. Clem, and L. K. Miller. 1994. An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs. J. Virol. 68:2521-2528.
6. 1-76. J. Virol. 58:7728-7737.
7. Clem, R. J., M. Fechheimer, and L. K. Miller. 1991. Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254:1388-1390.
8. Clem, R. J., J. M. Hardwick, and L. K. Miller. 1996. Anti-apoptotic genes of baculoviruses. Cell Death Differ. 3:9-16.
9. Clem, R. J., and L. K. Miller. 1994. Control of programmed cell death by the baculovirus genes p35 and iap. Mol. Cell. Biol. 14:5212-5222.
10. Crook, N. E., R. J. Clem, and L. K. Miller. 1993. An apoptosis-inhibiting baculovirus gene with a zinc linger-like motif. J. Virol. 67:2168-2174.
11. Deveraux, Q. L., and J. C. Reed. 1999. IAP family proteins-suppressors of apoptosis. Genes Dev. 13:239-252.
12. Deveraux, Q. L., N. Roy, H. R. Stennicke, T. Van Arsdale, Q. Zhou, S. M. Srinivasula, E. S. Alnemri, G. S. Salvesen, and J. C. Reed. 1948. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17:2215-2223.
13. Deveraux, Q. L., R. Takahashi, G. S. Salvesen, and J. C. Reed. 1997. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388:300-304.
14. Duckett, C. S., V. E. Nava, R. W. Gedrich, R. J. Clem, J. L. Van Dongen, M. C. Gilfillan, H. Shiels, J. M. Hardwick, and C. B. Thompson. 1996. A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. EMBO J. 15:2685-2694.
15. Harvey, A. J., A. P. Bidwai, and L. K. Miller. 1997. Doom, a product of the Drosophila mod(mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins. Mol. Cell. Biol. 17:2835-2843.
16. Harvey, A. J., H. Soliman, W. J. Kaiser, and L. K. Miller. 1997. Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line. Cell Death Differ. 4:733-744.
17. Hawkins, C. J., A. G. Uren, G. Hacker, and R. L. Medcalf, and D. L. Vaux. 1996. Inhibition of interleukin I-beta-convert ing enzyme-mediated apoptosis of mammalian cells by baculovirus IAP. Proc. Natl. Acad. Sci. USA 93: 13786-13790.
18. Hay, B. A., D. A. Wassarman, and G. M. Rubin. 1995. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell 83:1253-1262.
19. Hershberger, P. A., J. A. Dickson, and P. D. Friesen. 1992. Site-specific mutagenesis of the 35-kilodalton protein gene encoded by Autographa californica nuclear polyhedrosis virus: cell line-specific effects on virus replication. J. Virol. 66:5525-5533.
20. Hershberger, P. A., D. J. LaCount, and P. D. Friesen. 1994. The apoptotic suppressor P35 is required early during baculovirus replication and is targeted to the cytosol of infected cells. J. Virol. 68:3467-3477.
21. Hinds, M. G., R. S. Norton, D. L. Vaux, and C. L. Day. 1999. Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat. Struct. Biol. 6:648-651.
22. Jarvis, D. L. 1993. Effects of baculovirus infection on IE1-mediated foreign gene expression in stably transformed insect cells. J. Virol. 67:2583-2591.
23. Kaiser, W. J., D. Vucic, and L. K. Miller. 1998. The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase dr1CE. FEBS Lett. 440:243-248.
24. Kawasaki, H., D. C. Altieri, C. D. Lu, M. Toyoda, T. Tenjo, and N. Tanigawa. 1998. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 58:5071-5074.
25. LaCasse, E. C., S. Baird, R. G. Korneluk, and A. E. Mackenzie. 1998. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17:3247-3259.
26. LaCount, D. J., and P. D. Friesen. 1997. Role of early and late replication events in induction of apoptosis by baculoviruses. J. Virol. 71:1530-1537.
27. Lee, H. H., and L. K. Miller. 1978. Isolation of genotypic variants of Autographa californica nuclear polyhedrosis virus. J. Virol. 27:754-767.
28. Liston, P., S. S. Young, A. E. Mackenzie, and R. G. Korneluk. 1997. Life and death decisions-the role of the IAPs in modulating programmed cell death. Apoptosis 2:423-441.
29. Lu, C. D., D. C. Altieri, and N. Tanigawa. 1998. Expression of a novel anti-apoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 58:1808-1812.
30. Manji, G. A., R. R. Hozak, D. J. LaCount, and P. D. Friesen. 1997. Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell death. J. Virol. 71:4509-4516.
31. McCarthy, J. V., and V. M. Dixit. 1998. Apoptosis induced by Drosophila Reaper and Grim in a human system. Attenuation by Inhibitor of Apoptosis proteins (cIAPs). J. Biol. Chem. 273:24009-24015.
32. Miller, L. K. 1999. An exegesis of IAPs: salvation and surprises from BIR motifs. Trends Cell Biol. 9:323-328.
33. Miller, L. K., W. J. Kaiser, and S. Seshagiri. 1998. Baculovirus regulation of apoptosis. Semin. Virol. 8:445-452.
34. Rothe, M., M. G. Pan, W. J. Henzel, T. M. Ayres, and D. V. Goeddel. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83:1243-1252.
35. Roy, N., Q. L. Deveraux, R. Takahashi, G. S. Salvesen, and J. C. Reed. 1997. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16:6914-6925.
36. Roy, N., M. S. Mahadevan, M. McLean, G. Shutler, Z. Yaraghi, R. Farahani, S. Baird, A. Besner-Johnston, C. Lefebvre, X. Kang, M. Salih, H. Aubry, K. Tamai, X. Guan, P. Ioannou, T. O. Crawford, P. J. de Jong, L. Surh, J. Ikeda, R. G. Korneluk, and A. MacKenzie. 1995. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80:167-178.
37. Seshagiri, S., and L. K. Miller. 1997. Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1. Proc. Natl. Acad. Sci. USA 94:13606-13611.
38. Sun, C., M. Cai, A. H. Gunasekera, R. P. Meadows, H. Wang, H. Zhang, W. Wu, N. Xu, S. Ng, and S. W. Fesik. 1999. NMR structure and mutagenesis of the inhihitor-of-apoptosis protein XIAP. Nature 401:818-822.
39. Takahashi, R., Q. Deveraux, I. Tamm, K. Welsh, N. Assa-Munt, G. S. Salvesen, and J. C. Reed. 1998. A single BIR domain of XIAP sufficient for inhibiting caspases. J. Biol. Chem. 273:7787-7790.
40. Tamm, I., Y. Wang, E. Sausville, D. A. Scudiero, N. Vigna, T. Oltersdorf, and J. C. Reed. 1998. IAP-family protein Survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58:5315-5320.
41. Uren, A. G., E. J. Coulson, and D. L. Vaux. 1998. Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts. Trends Biochem. Sci. 23:159-162.
42. Uren, A. G., M. Pakusch, C. J. Hawkins, K. L. Puls, and D. L. Vaux. 1996. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc. Natl. Acad. Sci. USA 93:4974-4978.
43. Vaughn, J. L., R. H. Goodwin, G. L. Thompkins, and P. McCawley. 1977. Establishment of two insect cell lines from the insect Spodoptera frugiperda (Lepidoptera:Noctuidae). In Vitro 13:213-217.
44. Vaux, D. L., and S. J. Korsmeyer. 1999. Cell death in development. Cell 96: 245-254.
45. Vucic, D., W. J. Kaiser, A. J. Harvey, and L. K. Miller. 1997. Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs). Proc. Natl. Acad. Sci. USA 94:10183-10188.
46. Vucic, D., W. J. Kaiser, and L. K. Miller. 1998. Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM. Mol. Cell. Biol. 18:3300-3309.
47. Vucic, D., W. J. Kaiser, and L. K. Miller. 1998. A mutational analysis of the baculovirus inhibitor of apoptosis Op-IAP. J. Biol. Chem. 273:33915-33921.
48. Vucic, D., S. Seshagiri, and L. K. Miller. 1997. Characterization of reaperand FADD-induced apoptosis in a lepidopteran cell line. Mol. Cell. Biol. 17: 667-676.
49. Wang, S. L., C. J. Hawkins, S. J. Yoo, H. J. Muller, and B. A. Hay. 1999. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98:453-463.
50. Yamaguchi, K., S. Nagai, J. Ninomiya-Tsuji, M. Nishita, K. Tamai, K. Irie, N. Ueno, E. Nishida, H. Shibuya, and K. Matsumoto. 1999. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TABl-TAK1 in the BMP signaling pathway. EMBO J. 18:179-187.