-
1
-
-
0033574578
-
The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides
-
E.J. Ackermann J.K. Taylor R. Narayana The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides J Biol Chem 274 1999 11245
-
(1999)
J Biol Chem
, vol.274
, pp. 11245
-
-
Ackermann, E.J.1
Taylor, J.K.2
Narayana, R.3
-
2
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
B. Antonsson F. Conti A. Ciavatta Inhibition of Bax channel-forming activity by Bcl-2 Science 277 1997 370
-
(1997)
Science
, vol.277
, pp. 370
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
-
3
-
-
0034650523
-
Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria
-
B. Antonsson S. Montessuit S. Lauper Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria Biochem J 345 2000 271
-
(2000)
Biochem J
, vol.345
, pp. 271
-
-
Antonsson, B.1
Montessuit, S.2
Lauper, S.3
-
4
-
-
0033545722
-
Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations
-
G. Basanez A. Nechushtan O. Drozhinin Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations Proc Natl Acad Sci U S A 96 1996 5492
-
(1996)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5492
-
-
Basanez, G.1
Nechushtan, A.2
Drozhinin, O.3
-
5
-
-
0032827410
-
Mitochondrial transport of cations: Channels, exchangers, and permeability transition
-
P. Bernardi Mitochondrial transport of cations: Channels, exchangers, and permeability transition Physiol Rev 79 1999 1127
-
(1999)
Physiol Rev
, vol.79
, pp. 1127
-
-
Bernardi, P.1
-
6
-
-
0033520463
-
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes
-
S. Bialik V.L. Cryns A. Drincic The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes Circ Res 85 1999 403
-
(1999)
Circ Res
, vol.85
, pp. 403
-
-
Bialik, S.1
Cryns, V.L.2
Drincic, A.3
-
7
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
J.M. Boyd S. Malstrom T. Subramanian Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins Cell 79 1994 341
-
(1994)
Cell
, vol.79
, pp. 341
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
-
8
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
R.K. Bruick Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia Proc Natl Acad Sci U S A 97 2000 9082
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9082
-
-
Bruick, R.K.1
-
9
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
I. Budihardjo H. Oliver M. Lutter Biochemical pathways of caspase activation during apoptosis Annu Rev Dev Biol 15 1999 269
-
(1999)
Annu Rev Dev Biol
, vol.15
, pp. 269
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
-
10
-
-
0032504574
-
Mitochondrial control of apoptosis: The role of cytochrome c
-
J. Cai J. Yang D.P. Jones Mitochondrial control of apoptosis: The role of cytochrome c Biochim Biophys Acta 1366 1998 139
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 139
-
-
Cai, J.1
Yang, J.2
Jones, D.P.3
-
11
-
-
0029802591
-
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
X. Chen L.J. Ko L. Jayaraman p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells Genes Dev 10 1996 2438
-
(1996)
Genes Dev
, vol.10
, pp. 2438
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
-
12
-
-
0031455410
-
The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis
-
G. Chen R. Ray D. Dubik The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis J Exp Med 186 1997 1975
-
(1997)
J Exp Med
, vol.186
, pp. 1975
-
-
Chen, G.1
Ray, R.2
Dubik, D.3
-
13
-
-
0032932923
-
Nix and Nip3 form a subfamily of proapoptotic mitochondrial proteins
-
G. Chen J. Cizeau Vande Velde C. Nix and Nip3 form a subfamily of proapoptotic mitochondrial proteins J Biol Chem 274 1999 7
-
(1999)
J Biol Chem
, vol.274
, pp. 7
-
-
Chen, G.1
Cizeau, J.2
Vande Velde, C.3
-
14
-
-
0032745819
-
Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes
-
S.A. Cook P.H. Sugden A. Clerk Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes Circ Res 85 1999 940 949
-
(1999)
Circ Res
, vol.85
, pp. 940-949
-
-
Cook, S.A.1
Sugden, P.H.2
Clerk, A.3
-
16
-
-
0033565557
-
The mitochondrial permeability transition pore and its role in cell death
-
M. Crompton The mitochondrial permeability transition pore and its role in cell death Biochem J 341 1999 233
-
(1999)
Biochem J
, vol.341
, pp. 233
-
-
Crompton, M.1
-
17
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
E. Daugas S.A. Susin N. Zamzami Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis FASEB J 14 2000 729
-
(2000)
FASEB J
, vol.14
, pp. 729
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
-
18
-
-
0034617449
-
Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
-
E. Daugas D. Nochy L. Ravagnan Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis FEBS Lett 476 2000 118
-
(2000)
FEBS Lett
, vol.476
, pp. 118
-
-
Daugas, E.1
Nochy, D.2
Ravagnan, L.3
-
19
-
-
0033959317
-
Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
-
De Moissac D. R.M. Gurevich H. Zheng Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes J Mol Cell Cardiol 32 2000 53
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 53
-
-
De Moissac, D.1
Gurevich, R.M.2
Zheng, H.3
-
20
-
-
0033535350
-
Bid-induced conformational change of bax is responsible for mitochondrial cytochrome c release during apoptosis
-
S. Desagher A. Osen-Sand A. Nichols Bid-induced conformational change of bax is responsible for mitochondrial cytochrome c release during apoptosis J Cell Biol 144 1999 891
-
(1999)
J Cell Biol
, vol.144
, pp. 891
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
-
21
-
-
0034284637
-
Mitochondria as the central control point of apoptosis
-
S. Desagher J.C. Martinou Mitochondria as the central control point of apoptosis Trends Cell Biol 10 2000 369
-
(2000)
Trends Cell Biol
, vol.10
, pp. 369
-
-
Desagher, S.1
Martinou, J.C.2
-
22
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
Q.L. Deveraux R. Takahashi G.S. Salvesen X-linked IAP is a direct inhibitor of cell-death proteases Science 388 1997 300
-
(1997)
Science
, vol.388
, pp. 300
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
-
23
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
Q.L. Deveraux N. Roy H.R. Stennicke IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases EMBO J 17 1998 2215
-
(1998)
EMBO J
, vol.17
, pp. 2215
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
-
24
-
-
0033082995
-
IAP family proteins-suppressors of apoptosis
-
Q.L. Deveraux J.C. Reed IAP family proteins-suppressors of apoptosis Genes Dev 13 1999 239
-
(1999)
Genes Dev
, vol.13
, pp. 239
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
25
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c–dependent caspase activation by eliminating IAP inhibition
-
C. Du M. Fang Y. Li Smac, a mitochondrial protein that promotes cytochrome c–dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33
-
(2000)
Cell
, vol.102
, pp. 33
-
-
Du, C.1
Fang, M.2
Li, Y.3
-
26
-
-
0032487583
-
Bax-induced cytochrome c release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions
-
2+ ions J Cell Biol 143 1998 217
-
(1998)
J Cell Biol
, vol.143
, pp. 217
-
-
Eskes, R.1
Antonsson, B.2
Osen-Sand, A.3
-
27
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
R. Eskes S. Desagher B. Antonsson Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane Mol Cell Biol 20 2000 929
-
(2000)
Mol Cell Biol
, vol.20
, pp. 929
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
-
28
-
-
0032575705
-
A matter of life and cell death
-
G. Evan T. Littlewood A matter of life and cell death Science 281 1998 1317
-
(1998)
Science
, vol.281
, pp. 1317
-
-
Evan, G.1
Littlewood, T.2
-
29
-
-
0034604029
-
A receptor for phosphatidylserine-specific clearance of apoptotic cells
-
V.A. Fadok D.L. Bratton D.M. Rose A receptor for phosphatidylserine-specific clearance of apoptotic cells Nature 405 2000 85 90
-
(2000)
Nature
, vol.405
, pp. 85-90
-
-
Fadok, V.A.1
Bratton, D.L.2
Rose, D.M.3
-
30
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
-
D.M. Finucane E. Bossy-Wetzel N.J. Waterhouse Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL J Biol Chem 274 1999 2225
-
(1999)
J Biol Chem
, vol.274
, pp. 2225
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
-
31
-
-
0034710303
-
p38 MAP kinase mediates Bax translocation in nitric oxide-induced apoptosis in neurons
-
S. Ghatan S. Larner Y. Kinoshita p38 MAP kinase mediates Bax translocation in nitric oxide-induced apoptosis in neurons J Cell Biol 150 2000 335
-
(2000)
J Cell Biol
, vol.150
, pp. 335
-
-
Ghatan, S.1
Larner, S.2
Kinoshita, Y.3
-
33
-
-
0033535347
-
Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
-
G.J. Griffiths L. Dubrez C.P. Morgan Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis J Cell Biol 144 1999 903
-
(1999)
J Cell Biol
, vol.144
, pp. 903
-
-
Griffiths, G.J.1
Dubrez, L.2
Morgan, C.P.3
-
34
-
-
0032528118
-
Enforced dimerization of Bax results in its translocation, mitochondrial dysfunction and apoptosis
-
A. Gross J. Jockel M.C. Wei Enforced dimerization of Bax results in its translocation, mitochondrial dysfunction and apoptosis EMBO J 17 1998 3878
-
(1998)
EMBO J
, vol.17
, pp. 3878
-
-
Gross, A.1
Jockel, J.2
Wei, M.C.3
-
35
-
-
0033534446
-
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-xL prevents this release but not tumor necrosis factor-R1/Fas death
-
A. Gross X.M. Yin K. Wang Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-xL prevents this release but not tumor necrosis factor-R1/Fas death J Biol Chem 274 1999 1156
-
(1999)
J Biol Chem
, vol.274
, pp. 1156
-
-
Gross, A.1
Yin, X.M.2
Wang, K.3
-
36
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
A. Gross J.M. McDonnell S.J. Korsmeyer BCL-2 family members and the mitochondria in apoptosis Genes Dev 13 1999 1899
-
(1999)
Genes Dev
, vol.13
, pp. 1899
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
37
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
R. Hakem A. Hakem G.S. Duncan Differential requirement for caspase 9 in apoptotic pathways in vivo Cell 94 1998 339
-
(1998)
Cell
, vol.94
, pp. 339
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
-
38
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation-deficient p53
-
Y. Haupt S. Rowan E. Shaulian Induction of apoptosis in HeLa cells by transactivation-deficient p53 Genes Dev 9 1995 2170
-
(1995)
Genes Dev
, vol.9
, pp. 2170
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
-
39
-
-
0032870898
-
Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo
-
T.A. Holly A. Drincic Y. Byun Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo J Mol Cell Cardiol 31 1999 1709
-
(1999)
J Mol Cell Cardiol
, vol.31
, pp. 1709
-
-
Holly, T.A.1
Drincic, A.2
Byun, Y.3
-
40
-
-
0033597754
-
Cardiomyocyte apoptosis with enhanced expression of p53 and Bax in right ventricule after pulmonary arterial banding
-
S. Ikeda M. Hamada K. Hiwada Cardiomyocyte apoptosis with enhanced expression of p53 and Bax in right ventricule after pulmonary arterial banding Life Sci 65 1999 925
-
(1999)
Life Sci
, vol.65
, pp. 925
-
-
Ikeda, S.1
Hamada, M.2
Hiwada, K.3
-
41
-
-
0032806358
-
Apoptosis in cardiac disease
-
T.N. James Apoptosis in cardiac disease Am J Med 107 1999 606
-
(1999)
Am J Med
, vol.107
, pp. 606
-
-
James, T.N.1
-
42
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
J.M. Jurgensmeier Z. Xie Q. Deveraux Bax directly induces release of cytochrome c from isolated mitochondria Proc Natl Acad Sci U S A 95 1998 4997
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4997
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
-
43
-
-
0029861518
-
Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1
-
A. Karsan E. Yee J.M. Harlan Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1 J Biol Chem 271 1996 27201
-
(1996)
J Biol Chem
, vol.271
, pp. 27201
-
-
Karsan, A.1
Yee, E.2
Harlan, J.M.3
-
44
-
-
0030696785
-
Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms
-
A. Karsan E. Yee G.G. Poirier Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms Am J Pathol 151 1997 1775
-
(1997)
Am J Pathol
, vol.151
, pp. 1775
-
-
Karsan, A.1
Yee, E.2
Poirier, G.G.3
-
45
-
-
0033406781
-
Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH
-
A.R. Khaled K. Kim R. Hofmeister Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH Proc Natl Acad Sci U S A 96 1999 14476
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14476
-
-
Khaled, A.R.1
Kim, K.2
Hofmeister, R.3
-
46
-
-
0030870555
-
The bcl-2 gene product prevents programmed cell death of ventricular myocytes
-
Kirshenbaum L.A. de Moissac D. The bcl-2 gene product prevents programmed cell death of ventricular myocytes Circulation 96 1997 1580
-
(1997)
Circulation
, vol.96
, pp. 1580
-
-
Kirshenbaum, L.A.1
de Moissac, D.2
-
47
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
R.M. Kluck E. Bossy-Wetzel D.R. Green The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis Science 275 1997 1133
-
(1997)
Science
, vol.275
, pp. 1133
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
-
48
-
-
0033571045
-
The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
-
R.M. Kluck M.D. Esposti G. Perkins The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol J Cell Biol 147 1999 809
-
(1999)
J Cell Biol
, vol.147
, pp. 809
-
-
Kluck, R.M.1
Esposti, M.D.2
Perkins, G.3
-
49
-
-
0034009935
-
The role of apoptosis in vascular disease
-
M.M. Kockx M.W.M. Knaapen The role of apoptosis in vascular disease J Pathol 190 2000 267
-
(2000)
J Pathol
, vol.190
, pp. 267
-
-
Kockx, M.M.1
Knaapen, M.W.M.2
-
50
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
S. Krajewski M. Krajewska L.M. Ellerby Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia Proc Natl Acad Sci U S A 96 1999 5752
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5752
-
-
Krajewski, S.1
Krajewska, M.2
Ellerby, L.M.3
-
51
-
-
0034068601
-
Mitochondrial control of apoptosis
-
G. Kroemer J.C. Reed Mitochondrial control of apoptosis Nature Med 5 2000 513
-
(2000)
Nature Med
, vol.5
, pp. 513
-
-
Kroemer, G.1
Reed, J.C.2
-
52
-
-
0030453430
-
Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: Involvement of the sphingolipid signaling cascade in cardiac cell death
-
K.A. Krown M.T. Page C. Nguyen Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: Involvement of the sphingolipid signaling cascade in cardiac cell death J Clin Invest 98 1996 2854
-
(1996)
J Clin Invest
, vol.98
, pp. 2854
-
-
Krown, K.A.1
Page, M.T.2
Nguyen, C.3
-
53
-
-
0034725630
-
The destabilization of lipid membranes induced by the C-terminal fragment of caspase 8-cleaved bid is inhibited by the N-terminal fragment
-
G. Kudla S. Montessuit R. Eskes The destabilization of lipid membranes induced by the C-terminal fragment of caspase 8-cleaved bid is inhibited by the N-terminal fragment J Biol Chem 275 2000 22713
-
(2000)
J Biol Chem
, vol.275
, pp. 22713
-
-
Kudla, G.1
Montessuit, S.2
Eskes, R.3
-
54
-
-
0032493910
-
Reduced apoptosis and cytochrome c–mediated caspase activation in mice lacking caspase 9
-
K. Kuida T.F. Haydar C.Y. Kuan Reduced apoptosis and cytochrome c–mediated caspase activation in mice lacking caspase 9 Cell 94 1998 325
-
(1998)
Cell
, vol.94
, pp. 325
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
-
56
-
-
0034640102
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
-
K. Li Y. Li J.M. Shelton Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis Cell 101 2000 389
-
(2000)
Cell
, vol.101
, pp. 389
-
-
Li, K.1
Li, Y.2
Shelton, J.M.3
-
57
-
-
0032555697
-
Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
H. Li H. Zhu C.J. Xu Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491
-
(1998)
Cell
, vol.94
, pp. 491
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
-
58
-
-
0033229866
-
p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c–independent apoptosis blocked by Bcl-2
-
P.F. Li R. Dietz von Harsdorf R. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c–independent apoptosis blocked by Bcl-2 EMBO J 18 1999 6027
-
(1999)
EMBO J
, vol.18
, pp. 6027
-
-
Li, P.F.1
Dietz, R.2
von Harsdorf, R.3
-
59
-
-
0034682890
-
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
-
H. Li S.K. Kolluri J. Gu Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3 Science 289 2000 1159
-
(2000)
Science
, vol.289
, pp. 1159
-
-
Li, H.1
Kolluri, S.K.2
Gu, J.3
-
60
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
X. Liu C.N. Kim J. Yang Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c Cell 86 1996 147
-
(1996)
Cell
, vol.86
, pp. 147
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
-
62
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
X. Luo I. Budihardjo H. Zou Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 1998 481
-
(1998)
Cell
, vol.94
, pp. 481
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
-
63
-
-
0032559799
-
The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling
-
M. Mancini D.W. Nicholson S. Roy The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling J Cell Biol 140 1998 1485
-
(1998)
J Cell Biol
, vol.140
, pp. 1485
-
-
Mancini, M.1
Nicholson, D.W.2
Roy, S.3
-
64
-
-
0034717014
-
Deat signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signalling
-
N.D. Marchenko A. Zaika U.M. Moll Deat signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signalling J Biol Chem 275 2000 16202
-
(2000)
J Biol Chem
, vol.275
, pp. 16202
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
65
-
-
0032550363
-
The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
-
I. Marzo C. Brenner N. Zamzami The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins J Exp Med 187 1998 1261
-
(1998)
J Exp Med
, vol.187
, pp. 1261
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
-
67
-
-
0033888287
-
Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in artherosclerotic lesions coincide with p53
-
B. Metzler Y. Hu H. Dietrich Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in artherosclerotic lesions coincide with p53 Am J Pathol 156 2000 1875
-
(2000)
Am J Pathol
, vol.156
, pp. 1875
-
-
Metzler, B.1
Hu, Y.2
Dietrich, H.3
-
68
-
-
0028883179
-
Tumor supressor p53 is a direct transcriptional activator of the human bax gene
-
T. Miyashita J.C. Reed Tumor supressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293
-
(1995)
Cell
, vol.80
, pp. 293
-
-
Miyashita, T.1
Reed, J.C.2
-
69
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
M. Müller S. Wilder D. Bannasch p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs J Exp Med 188 1998 2033
-
(1998)
J Exp Med
, vol.188
, pp. 2033
-
-
Müller, M.1
Wilder, S.2
Bannasch, D.3
-
70
-
-
0034625352
-
Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation
-
K.M. Murphy U.N. Streips R.B. Lock Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation J Biol Chem 275 2000 17225
-
(2000)
J Biol Chem
, vol.275
, pp. 17225
-
-
Murphy, K.M.1
Streips, U.N.2
Lock, R.B.3
-
71
-
-
0030892234
-
Apoptosis by death factor
-
S. Nagata Apoptosis by death factor Cell 88 1997 355
-
(1997)
Cell
, vol.88
, pp. 355
-
-
Nagata, S.1
-
72
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
M. Narita S. Shimizu T. Ito Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria Proc Natl Acad Sci U S A 95 1998 14681
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14681
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
-
73
-
-
0033529281
-
Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy
-
J. Narula P. Pandey E. Arbustini Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy Proc Natl Acad Sci U S A 96 1999 8144
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8144
-
-
Narula, J.1
Pandey, P.2
Arbustini, E.3
-
75
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell-death
-
A. Nechustan C.L. Smith Y.T. Hsu Conformation of the Bax C-terminus regulates subcellular location and cell-death EMBO J 18 1999 2330
-
(1999)
EMBO J
, vol.18
, pp. 2330
-
-
Nechustan, A.1
Smith, C.L.2
Hsu, Y.T.3
-
76
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
E. Oda R. Ohki H. Murasawa Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis Science 288 2000 1053
-
(2000)
Science
, vol.288
, pp. 1053
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
-
77
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Z.N. Oltvai C.L. Milliman S.J. Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 1993 609
-
(1993)
Cell
, vol.74
, pp. 609
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
78
-
-
0033615649
-
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
-
J.G. Pastorino M. Tafani R.J. Rothman Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore J Biol Chem 274 1999 31734
-
(1999)
J Biol Chem
, vol.274
, pp. 31734
-
-
Pastorino, J.G.1
Tafani, M.2
Rothman, R.J.3
-
79
-
-
0033214912
-
Protein translocation in apoptosis
-
A. Porter Protein translocation in apoptosis Trends Cell Biol 9 1999 394
-
(1999)
Trends Cell Biol
, vol.9
, pp. 394
-
-
Porter, A.1
-
80
-
-
15844393657
-
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
-
J. Rotonda D.W. Nicholson K.M. Fazil The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis Nature Struct Biol 3 1996 619
-
(1996)
Nature Struct Biol
, vol.3
, pp. 619
-
-
Rotonda, J.1
Nicholson, D.W.2
Fazil, K.M.3
-
81
-
-
85119551266
-
-
Saito S, Hiroi Y, Zou Y, et al: Beta-adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes. J Biol Chem In press.
-
-
-
-
82
-
-
0034253592
-
BAX-dependent transport of cytochrome c reconstituted in pure liposomes
-
M. Saito S.J. Korsmeyer P.H. Schlesinger BAX-dependent transport of cytochrome c reconstituted in pure liposomes Nat Cell Biol 2 2000 553
-
(2000)
Nat Cell Biol
, vol.2
, pp. 553
-
-
Saito, M.1
Korsmeyer, S.J.2
Schlesinger, P.H.3
-
83
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
A. Saleh M.S. Srinivasula S. Acharya Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation J Biol Chem 274 1999 17941
-
(1999)
J Biol Chem
, vol.274
, pp. 17941
-
-
Saleh, A.1
Srinivasula, M.S.2
Acharya, S.3
-
84
-
-
0032541132
-
Detection of pro-caspase-3 in cytosol and mitochondria of various tissues
-
A. Samali B. Zhivotovsky D.P. Jones Detection of pro-caspase-3 in cytosol and mitochondria of various tissues FEBS Lett 431 1998 167
-
(1998)
FEBS Lett
, vol.431
, pp. 167
-
-
Samali, A.1
Zhivotovsky, B.2
Jones, D.P.3
-
85
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
C. Scaffidi S. Fulda A. Srinivasan Two CD95 (APO-1/Fas) signaling pathways EMBO J 17 1998 1675
-
(1998)
EMBO J
, vol.17
, pp. 1675
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
86
-
-
0030724539
-
Release of apoptogenic proteins from the mitochondrial intermembrane space during the mitochondrial permeability transition
-
J.L. Scarlett M.P. Murphy Release of apoptogenic proteins from the mitochondrial intermembrane space during the mitochondrial permeability transition FEBS Lett 418 1997 282
-
(1997)
FEBS Lett
, vol.418
, pp. 282
-
-
Scarlett, J.L.1
Murphy, M.P.2
-
87
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate selective dimerization with Bax
-
T.W. Sedlak Z.N. Oltvai E. Yang Multiple Bcl-2 family members demonstrate selective dimerization with Bax Proc Natl Acad Sci U S A 92 1995 7834
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7834
-
-
Sedlak, T.W.1
Oltvai, Z.N.2
Yang, E.3
-
88
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
S. Shimizu M. Narita Y. Tsujimoto Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC Nature 399 1999 483
-
(1999)
Nature
, vol.399
, pp. 483
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
89
-
-
0034724190
-
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
-
S. Shimizu A. Konishi T. Kodama BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death Proc Natl Acad Sci U S A 97 2000 3100
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3100
-
-
Shimizu, S.1
Konishi, A.2
Kodama, T.3
-
90
-
-
0034697365
-
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
-
S. Shimizu T. Ide T. Yanagida Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c J Biol Chem 275 2000 12321
-
(2000)
J Biol Chem
, vol.275
, pp. 12321
-
-
Shimizu, S.1
Ide, T.2
Yanagida, T.3
-
91
-
-
0030900472
-
Differentiation, dedifferentiation, and apoptosis of smooth muscle cells during the development of the human ductus arteriosus
-
Slomp J. Gittenberger-de Groot A.C. M.A. Glukhova Differentiation, dedifferentiation, and apoptosis of smooth muscle cells during the development of the human ductus arteriosus Arterioscler Thromb Vasc Biol 17 1997 1003
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 1003
-
-
Slomp, J.1
Gittenberger-de Groot, A.C.2
Glukhova, M.A.3
-
92
-
-
0032868105
-
Increased p53 protein expression in human failing myocardium
-
Song H. Conte J. Jr A.H. Foster Increased p53 protein expression in human failing myocardium J Heart Lung Transplant 18 1999 744
-
(1999)
J Heart Lung Transplant
, vol.18
, pp. 744
-
-
Song, H.1
Conte, J.2
Foster, A.H.3
-
93
-
-
0033579810
-
Mitochondrial release of caspase-2 and -9 during the apoptosis process
-
S.A. Susin H.K. Lorenzo N. Zamzani Mitochondrial release of caspase-2 and -9 during the apoptosis process J Exp Med 189 1999 381
-
(1999)
J Exp Med
, vol.189
, pp. 381
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzani, N.3
-
94
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
S.A. Susin N. Zamzami M. Castedo Bcl-2 inhibits the mitochondrial release of an apoptogenic protease J Exp Med 184 1996 1331
-
(1996)
J Exp Med
, vol.184
, pp. 1331
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
-
95
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
S.A. Susin H.K. Lorenzo N. Zamzami Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441
-
(1999)
Nature
, vol.397
, pp. 441
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
96
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden M.G. N.S. Chandel E.K. Williamson Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria Cell 91 1997 627
-
(1997)
Cell
, vol.91
, pp. 627
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
-
97
-
-
0032587982
-
Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
-
Vander Heiden M.G. N.S. Chandel P.T. Schumacker Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange Mol Cell 3 1999 159
-
(1999)
Mol Cell
, vol.3
, pp. 159
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Schumacker, P.T.3
-
98
-
-
0034712944
-
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
-
Vander Heiden M.G. N.S. Chandel X.X. Li Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival Proc Natl Acad Sci U S A 97 2000 4666
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4666
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Li, X.X.3
-
99
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
E.E. Varfolomeev M. Schuchmann V. Luria Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally Immunity 9 1998 267
-
(1998)
Immunity
, vol.9
, pp. 267
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
-
100
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
A.M. Verhagen P.G. Ekert M. Pakusch Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins Cell 102 2000 43
-
(2000)
Cell
, vol.102
, pp. 43
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
101
-
-
0033537768
-
Ca2+ induced apoptosis through calcineurin dephosphorylation of BAD
-
2+ induced apoptosis through calcineurin dephosphorylation of BAD Science 284 1999 339
-
(1999)
Science
, vol.284
, pp. 339
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
-
102
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
M.C. Wei T. Lindsten V.K. Mootha tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c Gene Dev 14 2000 2060 2071
-
(2000)
Gene Dev
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
-
103
-
-
0028170376
-
Structure and mechanism of interleukin-1β converting enzyme
-
K.P. Wilson J.A.F. Black J.A. Thomson Structure and mechanism of interleukin-1β converting enzyme Nature 370 1994 270
-
(1994)
Nature
, vol.370
, pp. 270
-
-
Wilson, K.P.1
Black, J.A.F.2
Thomson, J.A.3
-
104
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
K.G. Wolter Y.T. Hsu C.L. Smith Movement of Bax from the cytosol to mitochondria during apoptosis J Cell Biol 139 1997 1281
-
(1997)
J Cell Biol
, vol.139
, pp. 1281
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
-
105
-
-
0028008513
-
Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
-
J.D. Woronicz B. Calnan V. Ngo Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas Nature 367 1994 277
-
(1994)
Nature
, vol.367
, pp. 277
-
-
Woronicz, J.D.1
Calnan, B.2
Ngo, V.3
-
106
-
-
0034095121
-
Upregulation of p53 protein in rat heart subjected to a transient occlusion of the coronary artery followed by reperfusion
-
Z. Xie T. Koyama K. Abe Upregulation of p53 protein in rat heart subjected to a transient occlusion of the coronary artery followed by reperfusion Jpn J Physiol 50 2000 159
-
(2000)
Jpn J Physiol
, vol.50
, pp. 159
-
-
Xie, Z.1
Koyama, T.2
Abe, K.3
-
107
-
-
0033845122
-
Apoptosis in rat cardiac myocytes induced by Fas ligand: Priming for Fas-mediated apoptosis with doxorubicin
-
M. Yamaoka S. Yamaguchi T. Suzuki Apoptosis in rat cardiac myocytes induced by Fas ligand: Priming for Fas-mediated apoptosis with doxorubicin J Mol Cell Cardiol 32 2000 881
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 881
-
-
Yamaoka, M.1
Yamaguchi, S.2
Suzuki, T.3
-
108
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death
-
E. Yang J. Zha J. Jockel Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death Cell 80 1995 285
-
(1995)
Cell
, vol.80
, pp. 285
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
-
109
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
J. Yang X. Liu K. Bhala Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked Science 275 1997 1129
-
(1997)
Science
, vol.275
, pp. 1129
-
-
Yang, J.1
Liu, X.2
Bhala, K.3
-
110
-
-
0032031529
-
Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3
-
T.L. Yue C. Wang A.M. Romanic Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3 J Mol Cell Cardiol 30 1998 495
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 495
-
-
Yue, T.L.1
Wang, C.2
Romanic, A.M.3
-
111
-
-
0030584088
-
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X
-
J. Zha H. Harada E. Yang Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X Cell 87 1996 619
-
(1996)
Cell
, vol.87
, pp. 619
-
-
Zha, J.1
Harada, H.2
Yang, E.3
-
112
-
-
0032799633
-
Caspases: Their intracellular localization and translocation during apoptosis
-
B. Zhivotovski A. Samali A. Gahm Caspases: Their intracellular localization and translocation during apoptosis Cell Death Diff 6 1999 644
-
(1999)
Cell Death Diff
, vol.6
, pp. 644
-
-
Zhivotovski, B.1
Samali, A.2
Gahm, A.3
-
113
-
-
0033596980
-
An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
H. Zou Y. Li X. Liu An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 J Biol Chem 274 1999 11549
-
(1999)
J Biol Chem
, vol.274
, pp. 11549
-
-
Zou, H.1
Li, Y.2
Liu, X.3
|