RAG-1 mutations associated with B-Cell-negative SCID dissociate the nicking and transesterification steps of V(D)J recombination

Molecular and Cellular Biology

Volumn 21, Issue 12, 2001, Pages 3935-3946

  Li, Wenhui ^a,b   Chang, Fu Chung ^a   Desiderio, Stephen ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTEINE; DNA; GENE PRODUCT; GLUTAMINE; MAGNESIUM ION; MANGANESE; METAL ION; RAG1 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; B LYMPHOCYTE; CATALYSIS; COMBINED IMMUNODEFICIENCY; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; DNA BINDING; DNA CLEAVAGE; DNA STRUCTURE; ESTERIFICATION; GENE ACTIVITY; GENE MUTATION; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL; RECESSIVE GENE;

B-LYMPHOCYTES; BASE SEQUENCE; CATIONS, DIVALENT; CELL LINE; DNA; DNA PRIMERS; ESTERIFICATION; GENE REARRANGEMENT, B-LYMPHOCYTE; HOMEODOMAIN PROTEINS; HUMANS; MUTATION; RECOMBINATION, GENETIC; SEVERE COMBINED IMMUNODEFICIENCY;

EID: 0035000829     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.12.3935-3946.2001     Document Type: Article

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