메뉴 건너뛰기




Volumn 4, Issue 5, 2000, Pages 635-664

Adenosine receptors in neurological disorders

Author keywords

adenosine; adenosine receptors; CNS; neurological disorders

Indexed keywords


EID: 0001524498     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.4.5.635     Document Type: Review
Times cited : (47)

References (165)
  • 1
    • 0033971607 scopus 로고    scopus 로고
    • The role of receptor structure in determining adenosine receptor activity
    • OLAH M, STILES GL: The role of receptor structure in determining adenosine receptor activity. Pharmacol Ther. (2000) 85:55-75.
    • (2000) Pharmacol Ther. , vol.85 , pp. 55-75
    • Olah, M.1    Stiles, G.L.2
  • 2
    • 0032463415 scopus 로고    scopus 로고
    • Neuroprotection induced by stimulating A1 or blocking A2Aadenosine receptors: An apparent paradox
    • ONGINI E, SCHUBERT P: Neuroprotection induced by stimulating A1 or blocking A2Aadenosine receptors: an apparent paradox. DrugDev. Res. (1998) 45:387-393.
    • (1998) DrugDev. Res. , vol.45 , pp. 387-393
    • Ongini, E.1    Schubert, P.2
  • 3
    • 0033060914 scopus 로고    scopus 로고
    • Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy
    • WEISNER J, UGARKAR BG, CASTELLINO AJ et al.: Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy. J. Pharmacol. Exp. Ther. (1999) 289:1669-1677.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 1669-1677
    • Weisner, J.1    Ugarkar, B.G.2    Castellino, A.J.3
  • 4
    • 0029614786 scopus 로고
    • Effects of repeated administration of selective adenosine A1 and A2A receptor agonists on pentylenetetrazole-induced convulsions in the rat
    • ADAMI M, BERTORELLI R, FERRI N, FODDI MC, ONGINI E: Effects of repeated administration of selective adenosine A1 and A2A receptor agonists on pentylenetetrazole-induced convulsions in the rat. Eur. J. Pharmacol. (1995) 294:383-389.
    • (1995) Eur. J. Pharmacol. , vol.294 , pp. 383-389
    • Adami, M.1    Bertorelli, R.2    Ferri, N.3    Foddi, M.C.4    Ongini, E.5
  • 5
    • 0032540196 scopus 로고    scopus 로고
    • Adenosine receptor activation and nociception
    • SAWYNOK J: Adenosine receptor activation and nociception. Eur. J. Pharmacol. (1998) 317:1-11.
    • (1998) Eur. J. Pharmacol. , vol.317 , pp. 1-11
    • Sawynok, J.1
  • 6
    • 0032928706 scopus 로고    scopus 로고
    • Region-dependent difference in the sleep-promoting potency of an adenosine A2A receptor agonist
    • SATOH S, MATSUMARA H, KOIKE N, TOKUNAGA Y, MAEDA T, HAYAISHI O, Region-dependent difference in the sleep-promoting potency of an adenosine A2A receptor agonist. Eur. J. Neurosci. (1999) 11:1587-1597.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 1587-1597
    • Satoh, S.1    Matsumara, H.2    Koike, N.3    Tokunaga, Y.4    Maeda, T.5    Hayaishi, O.6
  • 7
    • 0030250999 scopus 로고    scopus 로고
    • Pharmacology of adenosine A2A receptors
    • ONGINI E, FREDHOLM BB: Pharmacology of adenosine A2A receptors. Trends Pharmacol. Sci. (1996) 17:364-372.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 364-372
    • Ongini, E.1    Fredholm, B.B.2
  • 8
    • 0030611334 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
    • RICHARSON PJ, KASE H, JENNER PG: Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease. Trends Pharmacol. Sci. (1997) 18:338-344.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 338-344
    • Richarson, P.J.1    Kase, H.2    Jenner, P.G.3
  • 9
    • 0030841177 scopus 로고    scopus 로고
    • Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2A receptor
    • LEDENT C, VAUGEOIS JM, SCHIFFMANN SN, PEDRAZZINI T et al: Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2A receptor. Nature (1997) 388:674-678.
    • (1997) Nature , vol.388 , pp. 674-678
    • Ledent, C.1    Vaugeois, J.M.2    Schiffmann, S.N.3    Pedrazzini, T.4
  • 10
    • 0033232779 scopus 로고    scopus 로고
    • A2A adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice
    • CHEN JF, HUANG Z, MA J et al: A2A adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice. J. Neurosci. (1999) 19:9192-9200.
    • (1999) J. Neurosci. , vol.19 , pp. 9192-9200
    • Chen, J.F.1    Huang, Z.2    Ma, J.3
  • 12
    • 80052091284 scopus 로고    scopus 로고
    • Altered synaptic transmission, reduced hypoxia response and hyperalgesia in adenosine A1 knockout mice
    • New Orleans, Louisiana, USA
    • JOHANSSON B, FREDHOLM BB, HEERLENIUS E et al: Altered synaptic transmission, reduced hypoxia response and hyperalgesia in adenosine A1 knockout mice. 30th Annual Meeting Society of Neuroscience. New Orleans, Louisiana, USA (2000).
    • (2000) 30th Annual Meeting Society of Neuroscience
    • Johansson, B.1    Fredholm, B.B.2    Heerlenius, E.3
  • 14
    • 0030958871 scopus 로고    scopus 로고
    • Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses
    • CALABRESI P, CENTONZE D, PISANI A, BERNARDI G: Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses. J. Neurosci. (1997) 17:4509-4516.
    • (1997) J. Neurosci. , vol.17 , pp. 4509-4516
    • Calabresi, P.1    Centonze, D.2    Pisani, A.3    Bernardi, G.4
  • 15
    • 0030861647 scopus 로고    scopus 로고
    • Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
    • FERRE' S, FREDHOLM BB, MORELLI M, POPOLI P, FUXE K: Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci. (1997) 20:482-487.
    • (1997) Trends Neurosci. , vol.20 , pp. 482-487
    • Ferre, S.1    Fredholm, B.B.2    Morelli, M.3    Popoli, P.4    Fuxe, K.5
  • 17
    • 0030716172 scopus 로고    scopus 로고
    • Distribution of adenosine receptors in the post-mortem human brain. An extended autoradiographic study
    • SVENNINGSSON P, HALL H, SEDVALL G, FREDHOLM BB: Distribution of adenosine receptors in the post-mortem human brain. An extended autoradiographic study. Synapse (1997) 27:322-335.
    • (1997) Synapse , vol.27 , pp. 322-335
    • Svenningsson, P.1    Hall, H.2    Sedvall, G.3    Fredholm, B.B.4
  • 18
    • 0032510948 scopus 로고    scopus 로고
    • Antagonists of receptor-G protein interface block Gi-coupled signal transduction
    • GILCHRIST A, MAZZONI MR, DINEEN B et al: Antagonists of receptor-G protein interface block Gi-coupled signal transduction. J. Biol. Chem. (1998) 273:14912-14919.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14912-14919
    • Gilchrist, A.1    Mazzoni, M.R.2    Dineen, B.3
  • 19
    • 0029917476 scopus 로고    scopus 로고
    • Adenosine inhibits L-and N-type calcium channels in pituitary melanotrophs. Evidence for the involvement of a G protein in calcium channel gating
    • MEI YA, LE FOLL F, VAUDRY H, CAZIN L: Adenosine inhibits L-and N-type calcium channels in pituitary melanotrophs. Evidence for the involvement of a G protein in calcium channel gating. J. Neuroendocrinol. (1996) 8:85-91.
    • (1996) J. Neuroendocrinol. , vol.8 , pp. 85-91
    • Mei, Y.A.1    Foll F, L.E.2    Vaudry, H.3    Cazin, L.4
  • 20
    • 0030610404 scopus 로고    scopus 로고
    • 1 receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression
    • BIBER K, KLOTZ KN, BERGER M, GEBICKE-HERBER PJ, VAN CALKER D: Adenosine A1 receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression. J. Neurosci. (1997) 17(13):4956-4964.
    • (1997) J. Neurosci. , vol.17 , Issue.13 , pp. 4956-4964
    • Biber, K.1    Klotz, K.N.2    Berger, M.3    Gebicke-Herber, P.J.4    Van Calker, D.5
  • 21
    • 0028179236 scopus 로고
    • 1 adenosine receptor expressed in Chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipaseCand arachidonate release
    • AKBAR M, OKAJIMA F, TOMURA H, SHIMEGI S, KONDO, Y: A single species of A1 adenosine receptor expressed in Chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipaseCand arachidonate release. Mol. Pharmacol. (1994) 45:1036-1042.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1036-1042
    • Akbar, M.1    Okajima, F.2    Tomura, H.3    Shimegi, S.4    Kondo, Y.5
  • 22
    • 0026520040 scopus 로고
    • Adenosine receptors: Pharmacology, structure-activity relationship and therapeutic potential
    • JACOBSON KA, VAN GALEN PJM, WILLIAMS M: Adenosine receptors: pharmacology, structure-activity relationship and therapeutic potential. J. Med. Chem. (1992) 35:407-422.
    • (1992) J. Med. Chem. , vol.35 , pp. 407-422
    • Jacobson, K.A.1    Van Galen, P.J.M.2    Williams, M.3
  • 23
    • 0031931065 scopus 로고    scopus 로고
    • Comparative pharmacology of human adenosine receptor subtype- characterization of stably transfected receptors in CHO cells
    • KLOTZ KN, HESSLING J, HEGLER J et al.: Comparative pharmacology of human adenosine receptor subtype-characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's Arch. Pharmacol. (1998) 357:1-9.
    • (1998) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.357 , pp. 1-9
    • Klotz, K.N.1    Hessling, J.2    Hegler, J.3
  • 24
    • 0029670309 scopus 로고    scopus 로고
    • 2A adenosine receptor antagonist, to rat striatal membranes
    • ZOCCHI C, ONGINI E, FERRARA S, BARALDI PG, DIONISOTTI S: Binding of the radioligand [3H]-SCH 58261, a new non-xanthine A2A adenosine receptor antagonist, to rat striatal membranes. Br. J. Pharmacol. (1996) 117:1381-1386.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1381-1386
    • Zocchi, C.1    Ongini, E.2    Ferrara, S.3    Baraldi, P.G.4    Dionisotti, S.5
  • 28
    • 17544384891 scopus 로고    scopus 로고
    • 3 adenosine receptors
    • VARANI K, MERIGHI S, GESSI S et al.: [3H]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. Mol. Pharmacol.(2000) 57:968-975.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 968-975
    • Varani, K.1    Merighi, S.2    Gessi, S.3
  • 29
    • 17044440786 scopus 로고    scopus 로고
    • 2A antagonist with potent anticataleptic activity
    • SHIMADA J, KOIKE N, NONAKA H et al.: Adenosine A2A antagonist with potent anticataleptic activity. Bioorg. Med. Chem. (1997) 7:2349-2352.
    • (1997) Bioorg. Med. Chem. , vol.7 , pp. 2349-2352
    • Shimada, J.1    Koike, N.2    Nonaka, H.3
  • 30
    • 0031838227 scopus 로고    scopus 로고
    • 1 receptors, using in vivo and in vitro techniques
    • MARSTON HM, FINLAYSON K, MAEMOTO T et al.: Pharmacological characterization of a simple behavioural response mediated selectively by central adenosine A1 receptors, using in vivo and in vitro techniques. J. Pharmacol. Exp. Ther. (1998) 285:1023-1030.
    • (1998) J. Pharmacol. Exp. Ther. , vol.285 , pp. 1023-1030
    • Marston, H.M.1    Finlayson, K.2    Maemoto, T.3
  • 32
    • 0030785555 scopus 로고    scopus 로고
    • Inhibi-toryandexcitatoryeffectsofadenosineantagonists on spontaneous locomotor activity in mice
    • FLORIO C, ROSATI AM, TRAVERSA U, VERTUA R: Inhibi- toryandexcitatoryeffectsofadenosineantagonists on spontaneous locomotor activity in mice. Life Sci. (1997) 60:1477-1486.
    • (1997) Life Sci. , vol.60 , pp. 1477-1486
    • Florio, C.1    Rosati, A.M.2    Traversa, U.3    Vertua, R.4
  • 36
    • 0025803956 scopus 로고
    • Behavioural effects of adenosine agonists: Evaluation by punishment, discrete shuttle avoidance and activity tests in mice
    • HARAGUCHI H, KURIBARA H: Behavioural effects of adenosine agonists: evaluation by punishment, discrete shuttle avoidance and activity tests in mice. Jpn. J. Pharmacol. (1991) 55:303-310.
    • (1991) Jpn. J. Pharmacol. , vol.55 , pp. 303-310
    • Haraguchi, H.1    Kuribara, H.2
  • 37
    • 0029658995 scopus 로고    scopus 로고
    • 2A receptor-mediated modulation of striatal acetylcholine release in vivo
    • KUROKAWA M, KOGA K, KASE H, NAKAMYRA J, KUWANA Y: Adenosine A2Areceptor-mediated modulation of striatal acetylcholine release in vivo. J. Neurochem. (1996) 66:1882-1888.
    • (1996) J. Neurochem. , vol.66 , pp. 1882-1888
    • Kurokawa, M.1    Koga, K.2    Kase, H.3    Nakamyra Kuwana J, Y.4
  • 38
    • 0033373020 scopus 로고    scopus 로고
    • Adenosine modulates synaptic plasticity in hippocampus slices from aged rats
    • CONSTENLA AR, DE MENDONCA A, RIBEIRO JA: Adenosine modulates synaptic plasticity in hippocampus slices from aged rats. Brain Res. (1999) 851:228-234.
    • (1999) Brain Res. , vol.851 , pp. 228-234
    • Constenla, A.R.1    De Mendonca, A.2    Ribeiro, J.A.3
  • 39
    • 0030935875 scopus 로고    scopus 로고
    • A role for adenosine in the regulation of long-term depression in the adult rat hippocampusin vitro
    • KEMP N, BASHIR ZI: A role for adenosine in the regulation of long-term depression in the adult rat hippocampusin vitro. Neurosci. Lett. (1997) 225:189-192
    • (1997) Neurosci. Lett. , vol.225 , pp. 189-192
    • Kemp, N.1    Bashir, Z.I.2
  • 40
    • 0027332570 scopus 로고
    • 6-cyclopentyladenosine and 8-cyclopentyl-1,3- dipropylxanthine on N-methyl-D-aspartate induced seizures in mice
    • VON LUBITZ DKJE, PAUL IA, CARTER MF, JACOBSON KA: Effects of N6-cyclopentyladenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice. Eur. J. Pharmacol. (1993) 249:265-270.
    • (1993) Eur. J. Pharmacol. , vol.249 , pp. 265-270
    • Von Lubitz, D.K.J.E.1    Paul, I.A.2    Carter, M.F.3    Jacobson, K.A.4
  • 41
    • 0027337982 scopus 로고
    • 6-[(R)-phenyl-isopropyl] adenosine-induced cognitive disturbance
    • SUZUKI F, SHIMADA J, SHIOZAKI S et al.: Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine-or N6-[(R)-phenyl-isopropyl]adenosine-induced cognitive disturbance. J. Med. Chem. (1993) 36:2508-2518.
    • (1993) J. Med. Chem. , vol.36 , pp. 2508-2518
    • Suzuki, F.1    Shimada, J.2    Shiozaki, S.3
  • 42
    • 0027370262 scopus 로고
    • Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility
    • ZHANG G,FRANKLIN PH, MURRAY TF: Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility. J. Pharmacol. Exp. Ther. (1993) 264:1415-1424.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 1415-1424
    • Zhang, G.1    Franklin, P.H.2    Murray, T.F.3
  • 43
    • 0028158694 scopus 로고
    • Status epilepticus may be caused by loss of adenosine anticonvulsant mechanism
    • YOUNG D, DRAGUNOW M: Status epilepticus may be caused by loss of adenosine anticonvulsant mechanism. Neuroscience (1994) 58:245-261.
    • (1994) Neuroscience , vol.58 , pp. 245-261
    • Young, D.1    Dragunow, M.2
  • 44
    • 0031904404 scopus 로고    scopus 로고
    • 3H]nitrobenzyl- thioinosine adenosine uptake site binding in the mouse brain after acute pentylenetetrazol-induced seizures
    • PAGONOPOULOU O, ANGELATOU F: Time development and regional distribution of [3H]nitrobenzyl-thioinosine adenosine uptake site binding in the mouse brain after acute pentylenetetrazol-induced seizures. J. Neurosci. Res. (1998) 53:433-442.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 433-442
    • Pagonopoulou, O.1    Angelatou, F.2
  • 45
    • 0032956116 scopus 로고    scopus 로고
    • Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice
    • DE SARRO GB, DE SARRO A, DONATO DI PAOLA E, BERTORELLI R: Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice. Eur. J. Pharmacol. (1999) 371:137-145.
    • (1999) Eur. J. Pharmacol. , vol.371 , pp. 137-145
    • De Sarro, G.B.1    De Sarro, A.2    Donato Di Paola, E.3    Bertorelli, R.4
  • 46
    • 0034697355 scopus 로고    scopus 로고
    • 1 adenosine receptors in rat hippocampus after kainic-acid induced limbic seizures
    • EKONOMOU A, SPERK G, KOSTOPOULOS G, ANGELATOU F: Reduction of A1 adenosine receptors in rat hippocampus after kainic-acid induced limbic seizures. Neurosci. Lett. (2000) 284:49-52.
    • (2000) Neurosci. Lett. , vol.284 , pp. 49-52
    • Ekonomou, A.1    Sperk, G.2    Kostopoulos, G.3    Angelatou, F.4
  • 48
    • 0030874747 scopus 로고    scopus 로고
    • 1 receptor activation preferentially protects cultured cerebellar neurons astrocytes against hypoxia-induced death
    • LOGAN M, SWEENEY ML: Adenosine A1 receptor activation preferentially protects cultured cerebellar neurons astrocytes against hypoxia-induced death. Mol. Chem. Neuropathol. (1997) 31:119-133.
    • (1997) Mol. Chem. Neuropathol. , vol.31 , pp. 119-133
    • Logan, M.1    Sweeney, M.L.2
  • 49
    • 0033597008 scopus 로고    scopus 로고
    • Adenosine and cerebral ischaemia: Therapeutic future or death of a brave concept?
    • VON LUBITZ DK: Adenosine and cerebral ischaemia: therapeutic future or death of a brave concept? Eur. J. Pharmacol. (1999) 371:85-102.
    • (1999) Eur. J. Pharmacol. , vol.371 , pp. 85-102
    • Von Lubitz, D.K.1
  • 50
    • 0024374922 scopus 로고
    • Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils
    • VON LUBITZ DKJE, DAMBROSIA JM, REDMON DJ: Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils. Neuroscience (1989) 2:451-457.
    • (1989) Neuroscience , vol.2 , pp. 451-457
    • Von Lubitz, D.K.J.E.1    Dambrosia, J.M.2    Redmon, D.J.3
  • 51
    • 0029417320 scopus 로고
    • 2 adenosine receptor antagonists on cerebral ischaemic injury in the gerbil
    • PHILLIS JW: The effectsofselective A1 and A2 adenosine receptor antagonists on cerebral ischaemic injury in the gerbil. Brain Res. (1995) 705:79-84.
    • (1995) Brain Res. , vol.705 , pp. 79-84
    • Phillis, J.W.1
  • 52
    • 0343852967 scopus 로고    scopus 로고
    • Neonatal cerebral hypoxia-ischemia: The effect of adenosine receptor antagonists
    • BONA E,ADEN U,GILLAND E,FREDHOLM BB, HAGBERG H: Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists. Neuropharmacology (1997) 36 1327-1338.
    • (1997) Neuropharmacology , vol.36 , pp. 1327-1338
    • Bona, E.1    Aden, U.2    Gilland, E.3    Fredholm, B.B.4    Hagberg, H.5
  • 53
    • 0024358991 scopus 로고
    • 2-Chloroadenosine attenuates kainic acid induced toxicity within the rat striatum: Relationship to release of glutamate and calcium influx
    • ARVIN B, NEVILLE NF, PAN J, ROBERTS PJ: 2-Chloroadenosine attenuates kainic acid induced toxicity within the rat striatum: relationship to release of glutamate and calcium influx. Br. J. Pharmacol. (1989) 98:225-253.
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 225-253
    • Arvin, B.1    Neville, N.F.2    Pan, J.3    Roberts, P.J.4
  • 54
    • 0027239643 scopus 로고
    • 1 receptor
    • MACGREGOR DG, MILLER DW, STONE TW: Mediation of neuroprotective action of R-phenylisopropyladen-osine through a centrally located adenosine A1 receptor. Br. J. Pharmacol. (1993) 110:470-476.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 470-476
    • MacGregor, D.G.1    Miller, D.W.2    Stone, T.W.3
  • 56
    • 0000707976 scopus 로고    scopus 로고
    • Adenosine receptor activation suppresses tactile hypersensitivity and potentiates spinal cord stimulation in mononeuropathic rats
    • CUI JG, SOLLEVI A, LINDEROTH B, MEYERSON BA: Adenosine receptor activation suppresses tactile hypersensitivity and potentiates spinal cord stimulation in mononeuropathic rats. Neurosci. Lett. (1997) 223 173-176.
    • (1997) Neurosci. Lett. , vol.223 , pp. 173-176
    • Cui, J.G.1    Sollevi, A.2    Linderoth, B.3    Meyerson, B.A.4
  • 57
    • 0032733045 scopus 로고    scopus 로고
    • Intrathecal adenosine does not relieve allodynia-like behavior in spinally injured rats
    • VON HEIJNE M, HAO JX, SOLLEVI A, XU XJ: Intrathecal adenosine does not relieve allodynia-like behavior in spinally injured rats. NeuroReport (1999) 10:3247-3251.
    • (1999) NeuroReport , vol.10 , pp. 3247-3251
    • Von Heijne, M.1    Hao, J.X.2    Sollevi, A.3    Xj, X.U.4
  • 59
    • 80052085479 scopus 로고    scopus 로고
    • ABT-702, a novel orally effective adenosine kinase (AK) inhibitor analgesic with antiinflammatory properties
    • KOWALUK EA, YU H, MIKUSA J et al.: ABT-702, a novel orally effective adenosine kinase (AK) inhibitor analgesic with antiinflammatory properties. Drug Dev. Res. (2000) 50:104.
    • (2000) Drug Dev. Res. , vol.50 , pp. 104
    • Kowaluk, E.A.1    H, Y.U.2    Mikusa, J.3
  • 60
    • 0011397802 scopus 로고    scopus 로고
    • Structure-activity relationship of a series of novel, non-nucleoside analogs as adenosine kinase inhibitors
    • LEE C, JIANG M, BHAGWAT S et al: Structure-activity relationship of a series of novel, non-nucleoside analogs as adenosine kinase inhibitors. DrugDev. Res. (2000) 50:62.
    • (2000) DrugDev. Res. , vol.50 , pp. 62
    • Lee, C.1    Jiang, M.2    Bhagwat, S.3
  • 61
    • 0030440984 scopus 로고    scopus 로고
    • Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists.J
    • LEE YW, YAKSH TL: Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists.J. Pharmacol Exp. Ther. (1996) 277:1642-1648.
    • (1996) Pharmacol Exp. Ther. , vol.277 , pp. 1642-1648
    • Lee, Y.W.1    Yaksh, T.L.2
  • 62
    • 0029052146 scopus 로고
    • Schizophrenia and chromosomal deletions within 22q11.2
    • LINDSAY EA, MORRIS MA, GOS A et al.: Schizophrenia and chromosomal deletions within 22q11.2. Am. J. Hum. Genet. (1995) 56:1502-1503.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1502-1503
    • Lindsay, E.A.1    Morris, M.A.2    Gos, A.3
  • 63
    • 0027007979 scopus 로고
    • Immunological identification of A2 adenosine receptors by two antipeptide antibody preparations
    • PALMER TM, JACOBSON KA, STILES GL: Immunological identification of A2 adenosine receptors by two antipeptide antibody preparations. Mol Pharmacol (1992) 42:391-397.
    • (1992) Mol Pharmacol , vol.42 , pp. 391-397
    • Palmer, T.M.1    Jacobson, K.A.2    Stiles, G.L.3
  • 64
    • 0032587930 scopus 로고    scopus 로고
    • Adenosine A2A receptor interactions with receptors for other neurotransmitters and neuromodulators
    • RIBEIRO JA: Adenosine A2A receptor interactions with receptors for other neurotransmitters and neuromodulators.Eur.J.Pharmacol (1999) 375:101-113.
    • (1999) Eur.J.Pharmacol , vol.375 , pp. 101-113
    • Ribeiro, J.A.1
  • 65
    • 0028146932 scopus 로고
    • Role of histidine residues in the adenosine A2A receptor ligand binding site
    • ASKALAN R, RICHARDSON PJ: Role of histidine residues in the adenosine A2A receptor ligand binding site. J. Neurochem. (1994) 63:1477-1484.
    • (1994) J. Neurochem. , vol.63 , pp. 1477-1484
    • Askalan, R.1    Richardson, P.J.2
  • 66
    • 0029058432 scopus 로고
    • 3H]CGS 21680 to rat brain using autoradiography
    • JOHANSSON B, FREDHOLM BB: Further characteriza tion of the binding of the adenosine receptor agonist, [3H]CGS 21680 to rat brain using autoradiography. Neuropharmacology (1995) 34:393-403.
    • (1995) Neuropharmacology , vol.34 , pp. 393-403
    • Johansson, B.1    Fredholm, B.B.2
  • 67
    • 0032538908 scopus 로고    scopus 로고
    • Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system
    • ROSIN DL, ROBEVA A, WOODARD RL, GUYENET PG, LINDEN J: Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system.J. Comp. Neurol (1998) 401:163-186.
    • (1998) J. Comp. Neurol , vol.401 , pp. 163-186
    • Rosin, D.L.1    Robeva, A.2    Woodard, R.L.3    Guyenet, P.G.4    Linden, J.5
  • 68
    • 0032781426 scopus 로고    scopus 로고
    • Distribution, biochemistry and function of striatal adenosine A2A receptors
    • SVENNINGSSON P, LE MOINE C, FISONE G, FREDHOLM BB: Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog. Neurobiol (1999) 59:355-396.
    • (1999) Prog. Neurobiol , vol.59 , pp. 355-396
    • Svenningsson, P.1    Moine C, L.E.2    Fisone, G.3    Fredholm, B.B.4
  • 69
    • 0026763441 scopus 로고
    • Molecular cloning of the rat A2A adenosine receptor; Selective co-expression with D2 dopamine receptors in rat striatum
    • FINK JS, WEAVER DR, RIVKEES SA et al: Molecular cloning of the rat A2A adenosine receptor; selective co-expression with D2 dopamine receptors in rat striatum. Mol Brain Res. (1992) 14:186-195.
    • (1992) Mol Brain Res. , vol.14 , pp. 186-195
    • Fink, J.S.1    Weaver, D.R.2    Rivkees, S.A.3
  • 70
    • 0030836031 scopus 로고    scopus 로고
    • Cellular expression of adenosine A2A receptor mRNA in the rat central nervous system with special reference to dopamine innervated areas
    • SVENNINGSSON P, LE MOINE C, KULL B, SUNAHARA R, BLOCH B, FREDHOLM BB: Cellular expression of adenosine A2A receptor mRNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience (1997) 80:1171-1185.
    • (1997) Neuroscience , vol.80 , pp. 1171-1185
    • Svenningsson, P.1    Moine C, L.E.2    Kull, B.3    Sunahara, R.4    Bloch, B.5    Fredholm, B.B.6
  • 71
    • 0033973302 scopus 로고    scopus 로고
    • 2+ channels in rat striatal cholinergic interneurons
    • SONG WJ, TKATCH T, SURMEIERD J: Adenosine receptor expression and modulation of Ca2+ channels in rat striatal cholinergic interneurons. J. Neurophysiol (2000) 83:322-332.
    • (2000) J. Neurophysiol , vol.83 , pp. 322-332
    • Song, W.J.1    Tkatch, T.2    Surmeierd, J.3
  • 73
    • 80052086124 scopus 로고    scopus 로고
    • G protein coupling of CGS 21680 binding sites in the rat hippocampus and cortex is different from that adenosine A1 and striatal A2A receptors
    • CUNHA RA, COSTANTINO MD, RIBEIRO JA: G protein coupling of CGS 21680 binding sites in the rat hippocampus and cortex is different from that adenosine A1 and striatal A2A receptors. Naunyn-Schmiedberg's Arch. Pharmacol. (1999) 51:199-206.
    • (1999) Naunyn-Schmiedberg's Arch. Pharmacol. , vol.51 , pp. 199-206
    • Cunha, R.A.1    Costantino, M.D.2    Ribeiro, J.A.3
  • 74
    • 0033582539 scopus 로고    scopus 로고
    • Expression of adenosine A2A receptors gene in the olfactory bulb and spinal cord of rat and mouse
    • KAELIN-LANG A, LAUTERBURG T, BURGUNDER JM: Expression of adenosine A2A receptors gene in the olfactory bulb and spinal cord of rat and mouse. Neurosci. Lett. (1999) 261:189-191.
    • (1999) Neurosci. Lett. , vol.261 , pp. 189-191
    • Kaelin-Lang, A.1    Lauterburg, T.2    Burgunder, J.M.3
  • 75
    • 0027332624 scopus 로고
    • A2A adenosine receptor gene expression in developing rat brain
    • WEAVER DR: A2A adenosine receptor gene expression in developing rat brain. Brain Res. Mol. Brain Res. (1993) 20:313-327.
    • (1993) Brain Res. Mol. Brain Res. , vol.20 , pp. 313-327
    • Weaver, D.R.1
  • 76
    • 0030748505 scopus 로고    scopus 로고
    • Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: Comparison with dopamine receptors
    • JOHANSSON B, GEORGIEV V, FREDHOLM BB: Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with dopamine receptors. Neuroscience (1997) 80:1187-1207.
    • (1997) Neuroscience , vol.80 , pp. 1187-1207
    • Johansson, B.1    Georgiev, V.2    Fredholm, B.B.3
  • 78
    • 0032588813 scopus 로고    scopus 로고
    • Activation of dopamine D2 receptor decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neuron via different mechanism
    • LINDSKOG M, SVENNINGSSON P, FREDHOLM BB, GREENGARD P, FISONE G: Activation of dopamine D2 receptor decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neuron via different mechanism. Neuroscience (1999) 88:1005-1008.
    • (1999) Neuroscience , vol.88 , pp. 1005-1008
    • Lindskog, M.1    Svenningsson, P.2    Fredholm, B.B.3    Greengard, P.4    Fisone, G.5
  • 80
    • 0033540078 scopus 로고    scopus 로고
    • NISHI A etal: Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    • BIBB JA, SNYDER GL, NISHI A etal: Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature (1999) 402:669-671.
    • (1999) Nature , vol.402 , pp. 669-671
    • Bibb, J.A.1    Snyder, G.L.2
  • 81
    • 0031283080 scopus 로고    scopus 로고
    • 2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes
    • GONCALVES ML, CUNHA RA, RIBEIRO JA: Adenosine A2A receptors facilitate 45 Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes. Neurosci. Lett. (1997) 238:73-77.
    • (1997) Neurosci. Lett. , vol.238 , pp. 73-77
    • Goncalves, M.L.1    Cunha, R.A.2    Ribeiro, J.A.3
  • 82
    • 0029977048 scopus 로고    scopus 로고
    • Dual signalling by the adenosine A2Areceptor involves activation of both N-and P-type calcium channels by different Gproteins and protein kinases in the same striatal nerve terminals
    • GUBIYZ AK, WIDDOWSON L, KUROKAWA M, KIRKPATRICK KA, RICHARDSON PJ: Dual signalling by the adenosine A2Areceptor involves activation of both N-and P-type calcium channels by different Gproteins and protein kinases in the same striatal nerve terminals. J. Neurochem. (1996) 67:374-381.
    • (1996) J. Neurochem. , vol.67 , pp. 374-381
    • Gubiyz, A.K.1    Widdowson, L.2    Kurokawa, M.3    Kirkpatrick, K.A.4    Richardson, P.J.5
  • 83
    • 0030610310 scopus 로고    scopus 로고
    • Desensiti-zation of adenosine A1 receptor by the A2A receptor in the rat striatum
    • DIXON AK, WIDDOWSON L, RICHARDSON PJ: Desensiti-zation of adenosine A1 receptor by the A2A receptor in the rat striatum. J. Neurochem. (1997) 69:315-321.
    • (1997) J. Neurochem. , vol.69 , pp. 315-321
    • Dixon, A.K.1    Widdowson, L.2    Richardson, P.J.3
  • 84
    • 0032078541 scopus 로고    scopus 로고
    • Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia
    • FUXE K, FERRE S, ZOLI M, AGNATI L: Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia. Brain Res. Rev. (1998) 26:258-273.
    • (1998) Brain Res. Rev. , vol.26 , pp. 258-273
    • Fuxe, K.1    Ferre, S.2    Zoli, M.3    Agnati, L.4
  • 85
    • 0027330136 scopus 로고
    • Effects of adenosine A1 and A2A receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices
    • JIN S, JOHANSSON B, FREDHOLM BB: Effects of adenosine A1 and A2A receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices. J. Pharmacol. Exp. Ther. (1993) 267:801-808.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 801-808
    • Jin, S.1    Johansson, B.2    Fredholm, B.B.3
  • 86
    • 0032029264 scopus 로고    scopus 로고
    • Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat
    • SVENNINGSSON P, NERGARDH R, FREDHOLM BB: Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat. Neuropharmacology (1998) 37:331-337.
    • (1998) Neuropharmacology , vol.37 , pp. 331-337
    • Svenningsson, P.1    Nergardh, R.2    Fredholm, B.B.3
  • 87
    • 0032901196 scopus 로고    scopus 로고
    • Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors
    • KULL B, ARSLAN G, NILSSON C, LORENZON A, SCHWABE U, FREDHOLM BB: Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochem. Pharmacol. (1999) VOL57:65-75.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 65-75
    • Kull, B.1    Arslan, G.2    Nilsson, C.3    Lorenzon, A.4    Schwabe, U.5    Fredholm, B.B.6
  • 88
    • 0032779014 scopus 로고    scopus 로고
    • Reciprocal interactions between adenosine A2A and dopamine D2 receptors co-transfected in CHO cells
    • KULL B, FERRE' S, ARLSAN G etal: Reciprocal interactions between adenosine A2A and dopamine D2 receptors co-transfected in CHO cells. Biochem. Pharmacol. (1999) 58:1035-1045.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1035-1045
    • Kull, B.1    Ferre, S.2    Arlsan, G.3
  • 89
    • 0033621564 scopus 로고    scopus 로고
    • Activation of adenosine A1 and A2A receptors modulates dopamine D2 receptor-induced responses in stably transfected human neuroblastoma cells
    • SALIM H, FERRE' S, DALAL A et al: Activation of adenosine A1 and A2A receptors modulates dopamine D2 receptor-induced responses in stably transfected human neuroblastoma cells. J. Neurochem. (2000) 74:432-439.
    • (2000) J. Neurochem. , vol.74 , pp. 432-439
    • Salim, H.1    Ferre, S.2    Dalal, A.3
  • 90
    • 0034652091 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of the dopamine and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2 and adenosine A2A receptors
    • SVENNINGSSON P, LINDSKOG M, LEDENT C et al.: Regulation of the phosphorylation of the dopamine and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2 and adenosine A2A receptors. Proc. Natl. Acad. Sci. USA (2000) 97:1856-1860.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1856-1860
    • Svenningsson, P.1    Lindskog, M.2    Ledent, C.3
  • 92
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purine and pyrimidines
    • RALEVIC V, BURNSTOCK G: Receptors for purine and pyrimidines. Pharmacol. Rev. (1998) 50:413-492.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 93
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • FREDHOLM BB, BATTIG K, HOLMEN J, NEHLIG A, ZVARTAU EE: Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol. Rev. (1999) 51:83-133.
    • (1999) Pharmacol. Rev. , vol.51 , pp. 83-133
    • Fredholm, B.B.1    Battig, K.2    Holmen, J.3    Nehlig, A.4    Zvartau, E.E.5
  • 94
    • 0028674643 scopus 로고
    • Pharmacology of the new selective A2A adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine
    • MONOPOLI A, CONTI A, ZOCCHI C et al: Pharmacology of the new selective A2A adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine. Arzneimittel-Forschung/DrugRes. (1994) 44:1296-1304.
    • (1994) Arzneimittel-Forschung/DrugRes. , vol.44 , pp. 1296-1304
    • Monopoli, A.1    Conti, A.2    Zocchi, C.3
  • 95
    • 0029127542 scopus 로고
    • The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2A selective adenosine receptor antagonist
    • POUCHER SM, KEDDIE JR, SINGH P et al: The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2A selective adenosine receptor antagonist. Br. J. Pharmacol (1995) 115:1096-1102.
    • (1995) Br. J. Pharmacol , vol.115 , pp. 1096-1102
    • Poucher, S.M.1    Keddie, J.R.2    Singh, P.3
  • 96
    • 0030029608 scopus 로고    scopus 로고
    • Effects of selective A1 and A2A agonists on amphetamine-induced locomotion and c-fos in striatum and nucleus accumbens
    • TURGEON SM, POLLACK AE, SCHUSHEIM L, FINK JS: Effects of selective A1 and A2A agonists on amphetamine-induced locomotion and c-fos in striatum and nucleus accumbens. Brain Res. (1996) 707:75-80.
    • (1996) Brain Res. , vol.707 , pp. 75-80
    • Turgeon, S.M.1    Pollack, A.E.2    Schusheim, L.3    Fink, J.S.4
  • 97
    • 0034726038 scopus 로고    scopus 로고
    • SCH58261 and ZM241385 differentially prevent the motor effects of CGS 21680 in mice: Evidence for a functional 'atypical' adenosine A(2A) receptor
    • EL YACOUBI M, LEDENT C, PARMENTIER M, COSTENTIN J, VAUGEOIS J: SCH58261 and ZM241385 differentially prevent the motor effects of CGS 21680 in mice: evidence for a functional 'atypical' adenosine A(2A) receptor. Eur.J. Pharmacol (2000) 401:63-67.
    • (2000) Eur.J. Pharmacol , vol.401 , pp. 63-67
    • Yacoubi M, E.L.1    Ledent, C.2    Parmentier, M.3    Costentin, J.4    Vaugeois, J.5
  • 98
    • 0030610127 scopus 로고    scopus 로고
    • Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats
    • MANDHANE SN, CHOPDE CT, GHOSH AK: Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats. Eur. J. Pharmacol (1997) 328:135-141.
    • (1997) Eur. J. Pharmacol , vol.328 , pp. 135-141
    • Mandhane, S.N.1    Chopde, C.T.2    Ghosh, A.K.3
  • 99
    • 0028177486 scopus 로고
    • Adenosine A2A receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats
    • MORELLI M, FENU S, PINNA A, DI CHIARA G: Adenosine A2A receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats. Eur J. Pharmacol (1994) 251:21-25.
    • (1994) Eur J. Pharmacol , vol.251 , pp. 21-25
    • Morelli, M.1    Fenu, S.2    Pinna, A.3    Chiara G, D.I.4
  • 100
    • 0344052684 scopus 로고    scopus 로고
    • Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys
    • GRONDIN R, BEDARD PJ, HADJ TAHAR A, GREGOIRE L, MORI A, KASE H: Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys. Neurology (1999) 52:1673-1677.
    • (1999) Neurology , vol.52 , pp. 1673-1677
    • Grondin, R.1    Bedard, P.J.2    Hadj Tahar, A.3    Gregoire, L.4    Mori, A.5    Kase, H.6
  • 101
    • 0031594271 scopus 로고    scopus 로고
    • Adenosine A2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian models
    • KANDA T, JACKSON MJ, SMITH LA etal: Adenosine A2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian models. Ann. Neurol. (1998) 43:507-513.
    • (1998) Ann. Neurol. , vol.43 , pp. 507-513
    • Kanda, T.1    Jackson, M.J.2    Smith, L.A.3
  • 102
    • 0029003784 scopus 로고
    • C-fos mediated antipsychotic-induced neurotensin gene expression in rodent striatum
    • ROBERTSON GS, TETZLAFF W, BEDARD A, ST-JEAN M, WIGLE N: c-fos mediated antipsychotic-induced neurotensin gene expression in rodent striatum. Neuroscience (1995) 67:325-344.
    • (1995) Neuroscience , vol.67 , pp. 325-344
    • Robertson, G.S.1    Tetzlaff, W.2    Bedard, A.3    St-Jean, M.4    Wigle, N.5
  • 103
    • 0027176632 scopus 로고
    • Adenosine agonist reduced conditioned avoidance responding in the rat
    • MARTIN GE, ROSSI DJ, JARVIS MF: Adenosine agonist reduced conditioned avoidance responding in the rat. Pharmacol. Biochem. Behav. (1993) 45:951-958.
    • (1993) Pharmacol. Biochem. Behav. , vol.45 , pp. 951-958
    • Martin, G.E.1    Rossi, D.J.2    Jarvis, M.F.3
  • 104
    • 0029671207 scopus 로고    scopus 로고
    • Selective A2A receptor/dopamine D2 receptor interactions in animal models of schizophrenia
    • KAFKA SH, CORBETT R: Selective A2A receptor/dopamine D2 receptor interactions in animal models of schizophrenia. Eur. J. Pharmacol. (1996) 295:263-268.
    • (1996) Eur. J. Pharmacol. , vol.295 , pp. 263-268
    • Kafka, S.H.1    Corbett, R.2
  • 105
    • 0030612294 scopus 로고    scopus 로고
    • Adenosine A2A receptors in the nucleus accumbens modulate prepulse inhibition of the startle response
    • HAUBER W, KOCH M: Adenosine A2A receptors in the nucleus accumbens modulate prepulse inhibition of the startle response. NeuroReport (1997) 8:1515-1518.
    • (1997) NeuroReport , vol.8 , pp. 1515-1518
    • Hauber, W.1    Koch, M.2
  • 106
    • 0028988522 scopus 로고
    • Adenosine A2 receptors stimulate c-fos expression in striatal neurons of 6-hydroxydopamine-lesioned rats
    • MORELLI M, PINNA A, WARDAS J, DI CHIARA G: Adenosine A2 receptors stimulate c-fos expression in striatal neurons of 6-hydroxydopamine-lesioned rats. Neuroscience (1995) 67:49-55.
    • (1995) Neuroscience , vol.67 , pp. 49-55
    • Morelli, M.1    Pinna, A.2    Wardas, J.3    Chiara G, D.I.4
  • 107
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: Hedonic homeostatic dysregulation
    • KOOB GF, LE MOAL M: Drug abuse: hedonic homeostatic dysregulation. Science (1997) 278:52-58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Moal M, L.E.2
  • 108
    • 0032925631 scopus 로고    scopus 로고
    • Facilitation of sexual behaviour in male rats following D-amphetamine-induced behavioural sensitization
    • FIORINO DF, PHILLIPS AG: Facilitation of sexual behaviour in male rats following D-amphetamine-induced behavioural sensitization. Psychopharma-cology (1999) 142:200-208.
    • (1999) Psychopharma-cology , vol.142 , pp. 200-208
    • Fiorino, D.F.1    Phillips, A.G.2
  • 109
    • 0028914467 scopus 로고
    • Molecular mechanisms of drug reinforcement and addiction
    • SELF DW, NESTLER EJ: Molecular mechanisms of drug reinforcement and addiction. Ann. Rev. Neurosci. (1995) 18:463-495.
    • (1995) Ann. Rev. Neurosci. , vol.18 , pp. 463-495
    • Self, D.W.1    Nestler, E.J.2
  • 110
    • 0027448029 scopus 로고
    • Locomotor activity in mice during chronic treatment with caffeine and withdrawal
    • NIKODIJEVIC O, JACOBSON KA: Locomotor activity in mice during chronic treatment with caffeine and withdrawal. Pharmacol. Biochem. Behav. (1993) 44:199-216.
    • (1993) Pharmacol. Biochem. Behav. , vol.44 , pp. 199-216
    • Nikodijevic, O.1    Jacobson, K.A.2
  • 111
    • 0032562439 scopus 로고    scopus 로고
    • Differential effects of adenosine A1 and A2 receptor agonists on dopamine receptor agonist-induced behavioural responses in rats
    • RIMONDINI R, FERRE' S, GIMENEZ-LLORT L, OGREN SO, FUXE K: Differential effects of adenosine A1 and A2 receptor agonists on dopamine receptor agonist-induced behavioural responses in rats. Eur. J. Pharmacol. (1998) 347:153-158.
    • (1998) Eur. J. Pharmacol. , vol.347 , pp. 153-158
    • Rimondini, R.1    Ferre, S.2    Gimenez-Llort, L.3    Ogren, S.O.4    Fuxe, K.5
  • 112
    • 0034037134 scopus 로고    scopus 로고
    • Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A2A adenosine receptors
    • CHEN JF, BEILSTEIN M, TURNER TJ et al.: Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A2A adenosine receptors. Neuroscience (2000) 97:195-204.
    • (2000) Neuroscience , vol.97 , pp. 195-204
    • Chen, J.F.1    Beilstein, M.2    Turner, T.J.3
  • 114
    • 0033573531 scopus 로고    scopus 로고
    • Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats
    • BALDO BA, KOOB GF, MARKOU A: Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats. J. Neurosci. (1999) 19:11017-11026.
    • (1999) J. Neurosci. , vol.19 , pp. 11017-11026
    • Baldo, B.A.1    Koob, G.F.2    Markou, A.3
  • 115
    • 0030061684 scopus 로고    scopus 로고
    • Adenosine receptor agonists attenuate and adenosine receptor antagonists exacerbate opiate withdrawal signs
    • KAPLAN GB, SEARS MT: Adenosine receptor agonists attenuate and adenosine receptor antagonists exacerbate opiate withdrawal signs. Psychopharmacology (1996) 123:64-70.
    • (1996) Psychopharmacology , vol.123 , pp. 64-70
    • Kaplan, G.B.1    Sears, M.T.2
  • 116
    • 0032078547 scopus 로고    scopus 로고
    • The DARPP-32/protein phosphatase-1 cascade:amodel for signal integration
    • GREENGARD P, NAIM AC, GIRAULT JA et al.: The DARPP-32/protein phosphatase-1 cascade:amodel for signal integration. Brain Res. Brain Res. Rev. (1998) 26:274-284.
    • (1998) Brain Res. Brain Res. Rev. , vol.26 , pp. 274-284
    • Greengard, P.1    Naim, A.C.2    Girault, J.A.3
  • 117
    • 0032925164 scopus 로고    scopus 로고
    • Adenosine in sleep and wakefulness
    • PORKKA-HEISKANEN T: Adenosine in sleep and wakefulness. Ann. Med. (1999) 31:125-129
    • (1999) Ann. Med. , vol.31 , pp. 125-129
    • Porkka-Heiskanen, T.1
  • 118
    • 0029658934 scopus 로고    scopus 로고
    • 6-cyclopentyladenosine and caffeine onsleep regulation in the rat
    • SCHWIERIN B, BORBELY AA, TOBLER I: Effects of N6-cyclopentyladenosine and caffeine onsleep regulation in the rat. Eur. J. Pharmacol. (1996) 300:163-171.
    • (1996) Eur. J. Pharmacol. , vol.300 , pp. 163-171
    • Schwierin, B.1    Borbely, A.A.2    Tobler, I.3
  • 119
    • 0033986389 scopus 로고    scopus 로고
    • Sleep-inducing effects of adenosine microinjections into the medial preoptic area are blocked by flumazenil
    • MENDELSON W: Sleep-inducing effects of adenosine microinjections into the medial preoptic area are blocked by flumazenil. Brain Res. (2000) 852:479-481.
    • (2000) Brain Res. , vol.852 , pp. 479-481
    • Mendelson, W.1
  • 120
    • 0024478297 scopus 로고
    • 1 receptors inhibit adenylate cyclase activity and neurotrasmitter release and hyperpolarize pyramidal neurons in rat hippocampus
    • DUNWIDDIE TV, FREDHOLM BB: Adenosine A1 receptors inhibit adenylate cyclase activity and neurotrasmitter release and hyperpolarize pyramidal neurons in rat hippocampus. J. Pharmacol. Exp. Ther. (1989) 249:31-37.
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 31-37
    • Dunwiddie, T.V.1    Fredholm, B.B.2
  • 121
    • 0030268068 scopus 로고    scopus 로고
    • 2A-receptor
    • FIEBICH BL, BIBER K, LIEB K et al.: Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2A-receptor. Glia (1996) 18:152-160.
    • (1996) Glia , vol.18 , pp. 152-160
    • Fiebich, B.L.1    Biber, K.2    Lieb, K.3
  • 122
    • 0032217044 scopus 로고    scopus 로고
    • 2A receptorsbySCH 58261 results in neuroprotective effects in cerebral ischaemia in rats
    • MONOPOLI A, LOZZA G, FORLANI A, MATTAVELLI A, ONGINI E: Blockadeof adenosine A2A receptorsbySCH 58261 results in neuroprotective effects in cerebral ischaemia in rats. NeuroReport (1998) 9:3955-3959.
    • (1998) NeuroReport , vol.9 , pp. 3955-3959
    • Monopoli, A.1    Lozza, G.2    Forlani, A.3    Mattavelli, A.4    Ongini, E.5
  • 123
    • 0003025448 scopus 로고    scopus 로고
    • Adenosine receptors, kynurenines and neuroprotection
    • STONE TW, BEHAN WMH: Adenosine receptors, kynurenines and neuroprotection. Drug Dev. Res. (2000) 50:15.
    • (2000) Drug Dev. Res. , vol.50 , pp. 15
    • Stone, T.W.1    Behan, W.M.H.2
  • 124
    • 0002127016 scopus 로고    scopus 로고
    • 2A receptor blockade prevents EEG and motor abnormalities in a rat model of Huntington's disease
    • POPOLI P, PEZZOLA A, REGGIO R, MALCHIODI AF, FALCHI M: Adenosine A2A receptor blockade prevents EEG and motor abnormalities in a rat model of Huntington's disease. Drug Dev. Res. (2000) 50:69.
    • (2000) Drug Dev. Res. , vol.50 , pp. 69
    • Popoli, P.1    Pezzola, A.2    Reggio, R.3    Malchiodi, A.F.4    Falchi, M.5
  • 126
    • 0032710609 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase stimulates dopamin-ergic neurodegenerationinthe MPTP modelofParkin-son's disease
    • LIBERATORE GT, JACKSON-LEWIS V, VUKOSAVIC S et al.: Inducible nitric oxide synthase stimulates dopamin-ergic neurodegenerationinthe MPTP modelofParkin-son's disease. Nature Med. (1999) 5:1403-1409.
    • (1999) Nature Med. , vol.5 , pp. 1403-1409
    • Liberatore, G.T.1    Jackson-Lewis, V.2    Vukosavic, S.3
  • 127
    • 0034192229 scopus 로고    scopus 로고
    • Nitric oxide, glial cells and neuronal degeneration in parkinsonism
    • HIRSH EC, HUNOT S: Nitric oxide, glial cells and neuronal degeneration in parkinsonism. Trends Pharmacol. Sci. (2000) 21:163-165
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 163-165
    • Hirsh, E.C.1    Hunot, S.2
  • 128
    • 0033380858 scopus 로고    scopus 로고
    • Brain adenosine receptors as targets for therapeutic intervention in neurodegenerative disease
    • ABBRACCHIO MP, CATTABENI F: Brain adenosine receptors as targets for therapeutic intervention in neurodegenerative disease. Ann. NY Acad. Sci. (1999) 890:79-92.
    • (1999) Ann. NY Acad. Sci. , vol.890 , pp. 79-92
    • Abbracchio, M.P.1    Cattabeni, F.2
  • 129
    • 0034647059 scopus 로고    scopus 로고
    • Early kynurenergic impairment in Huntington's disease and in transgenic animal model
    • GUIDETTI P, REDDY PH, TAGLE DA, SCHWAREZ R: Early kynurenergic impairment in Huntington's disease and in transgenic animal model. Neurosci. Lett. (2000) 283:233-235.
    • (2000) Neurosci. Lett. , vol.283 , pp. 233-235
    • Guidetti, P.1    Reddy, P.H.2    Tagle, D.A.3    Schwarez, R.4
  • 130
    • 0034094627 scopus 로고    scopus 로고
    • Early and late environmental risk factors for schizophrenia
    • MCDONALD C, MURRAY RM: Early and late environmental risk factors for schizophrenia. Brain Res. Brain Res. Rev. (2000) 31:130-137.
    • (2000) Brain Res. Brain Res. Rev. , vol.31 , pp. 130-137
    • McDonald, C.1    Murray, R.M.2
  • 131
    • 13044276244 scopus 로고    scopus 로고
    • A decrease of reelin expression as a putative vulnerability factor in schizophrenia
    • IMPAGNATIELLO F, GUIDOTTI AR, PESOLD C et al.: A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proc. Natl. Acad. Sci. USA (1998) 95:15718-15723
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15718-15723
    • Impagnatiello, F.1    Guidotti, A.R.2    Pesold, C.3
  • 134
    • 0033358864 scopus 로고    scopus 로고
    • Protein phosphatase 1 modulation of neostriatal AMPA channels: Regulation by DARPP-32 and spinophilin
    • YAN Z, HSICH-WILSON L, FENG J et al.: Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin. Nature Neurosci. (1999) 2:13-17.
    • (1999) Nature Neurosci. , vol.2 , pp. 13-17
    • Yan, Z.1    Hsich-Wilson, L.2    Feng, J.3
  • 135
    • 0033461157 scopus 로고    scopus 로고
    • The role of nucleus accumbens dopamine in motivated behaviour: A unifying interpretation with special reference to reward-seeking
    • IKEMOTO S, PANKSEPP J: The role of nucleus accumbens dopamine in motivated behaviour: a unifying interpretation with special reference to reward-seeking. Brain Res. Brain Res. Rev. (1999) 31:6-41.
    • (1999) Brain Res. Brain Res. Rev. , vol.31 , pp. 6-41
    • Ikemoto, S.1    Panksepp, J.2
  • 136
    • 0026616833 scopus 로고
    • RFL9 encodes an A2b-adenosine receptor
    • RIVKEES SA, REPPERT SM: RFL9 encodes an A2b-adenosine receptor. Mol. Endocrinol. (1992) 6:1598-1604.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1598-1604
    • Rivkees, S.A.1    Reppert, S.M.2
  • 138
    • 0028265842 scopus 로고
    • Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells
    • MARQUART DL, WALKER LL, HEINEMANN S: Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells. J. Immunol. (1994) 152:4508-4515.
    • (1994) J. Immunol. , vol.152 , pp. 4508-4515
    • Marquart, D.L.1    Walker, L.L.2    Heinemann, S.3
  • 139
    • 0029015445 scopus 로고
    • Cloning and chromosomal localization of the human A2b adenosine receptor gene (ADORA2B) and its pseudogene
    • JACOBSON MA, JOHNSON RG, LUNEAU CJ, SALVATORE CA: Cloning and chromosomal localization of the human A2b adenosine receptor gene (ADORA2B) and its pseudogene. Genomics (1995) 27:374-376.
    • (1995) Genomics , vol.27 , pp. 374-376
    • Jacobson, M.A.1    Johnson, R.G.2    Luneau, C.J.3    Salvatore, C.A.4
  • 140
    • 0029018445 scopus 로고
    • Productions and characterization of multiple antigenic peptide antibodies to the adenosine A2b receptor
    • PUFFINBARGER NK, HANSEN KR, RESTA R et al.: Productions and characterization of multiple antigenic peptide antibodies to the adenosine A2b receptor. Mol. Pharmacol. (1995) 47:1126-1132.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1126-1132
    • Puffinbarger, N.K.1    Hansen, K.R.2    Resta, R.3
  • 141
    • 0030702041 scopus 로고    scopus 로고
    • Structure-function analysis of inhibitory adenosine receptor regulation
    • PALMER TM, STILES GL: Structure-function analysis of inhibitory adenosine receptor regulation. Neuropharmacology (1997) 36:1141-1141.
    • (1997) Neuropharmacology , vol.36 , pp. 1141-1141
    • Palmer, T.M.1    Stiles, G.L.2
  • 143
    • 0027461754 scopus 로고
    • 2+ current in hippocampal CA3 neurons
    • MOGUL DJ, ADAMS ME, FOX AP: Differential activation of adenosine receptors decreases N-type but potenti ates P-type Ca2+current in hippocampal CA3 neurons. Neuron (1993) 10:327-334.
    • (1993) Neuron , vol.10 , pp. 327-334
    • Mogul, D.J.1    Adams, M.E.2    Fox, A.P.3
  • 144
    • 0030610395 scopus 로고    scopus 로고
    • 2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus
    • KESSEY K, TROMMER BL, OVERSTREET LS, JI T, MOGUL DJ: A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus. Brain Res. (1997) 756:184-190.
    • (1997) Brain Res. , vol.756 , pp. 184-190
    • Kessey, K.1    Trommer, B.L.2    Overstreet, L.S.3    T, J.I.4    Mogul, D.J.5
  • 145
    • 0028176413 scopus 로고
    • 2B-receptor-mediated cyclic AMP accumulation in primary rat astrocytes
    • PEAKMAN MC, HILL SJ: Adenosine A2B-receptor-mediated cyclic AMP accumulation in primary rat astrocytes. Br. J. Pharmacol. (1994) 111:191-198.
    • (1994) Br. J. Pharmacol. , vol.111 , pp. 191-198
    • Peakman, M.C.1    Hill, S.J.2
  • 147
    • 0028972108 scopus 로고
    • 2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma
    • FEOKTISTOV I, BIAGGIONI I: Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J. Clin. Invest. (1995) 96:1979-1986.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1979-1986
    • Feoktistov, I.1    Biaggioni, I.2
  • 148
    • 0027207785 scopus 로고
    • Acetylcholine output from the ischemic rat cerebral cortex: Effects of adenosine agonists
    • PHILLIS JW, SMITH-BARBOUR M, PERKINS LM, O'REGAN MH: Acetylcholine output from the ischemic rat cerebral cortex: effects of adenosine agonists. Brain Res. (1993) 613:337-340
    • (1993) Brain Res. , vol.613 , pp. 337-340
    • Phillis, J.W.1    Smith-Barbour, M.2    Perkins, L.M.3    O'Regan, M.H.4
  • 149
    • 0027538075 scopus 로고
    • Effect of adenosine receptor agonists on spontaneous and K(+)-evoked acetylcholine release from the in vivo rat cerebral cortex
    • PHILLIS JW, O'REGAN MH, PERKINS LM: Effect of adenosine receptor agonists on spontaneous and K(+)-evoked acetylcholine release from the in vivo rat cerebral cortex. Brain Res. (1993) 605:293-297.
    • (1993) Brain Res. , vol.605 , pp. 293-297
    • Phillis, J.W.1    O'Regan, M.H.2    Perkins, L.M.3
  • 150
    • 0030570390 scopus 로고    scopus 로고
    • 2 receptors modulate extracellular dopamine levels in rat striatum
    • OKADA M, MIZUNO K, KANEKO S: Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum. Neurosci. Lett. (1996) 21:53-56.
    • (1996) Neurosci. Lett. , vol.21 , pp. 53-56
    • Okada, M.1    Mizuno, K.2    Kaneko, S.3
  • 151
    • 0032813963 scopus 로고    scopus 로고
    • Adenosine, mast cells and asthma
    • FORSYTHE P, ENNIS M: Adenosine, mast cells and asthma. Inflamm. Res. (1999) 48:301-307.
    • (1999) Inflamm. Res. , vol.48 , pp. 301-307
    • Forsythe, P.1    Ennis, M.2
  • 153
    • 0025825121 scopus 로고
    • Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermio-genesis
    • MEYERHOF W, MULLER-BRECHLIN R, RICHTER D: Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermio-genesis. FEBS Lett. (1991) 284:155-160.
    • (1991) FEBS Lett. , vol.284 , pp. 155-160
    • Meyerhof, W.1    Muller-Brechlin, R.2    Richter, D.3
  • 154
    • 0027202159 scopus 로고
    • 3 adenosine receptorwith widespread tissue distribution
    • LINDEN J, TAYLOR HE, ROBEVA AS et al: Molecular cloning and functional expression of a sheep A3 adenosine receptorwith widespread tissue distribution. Mol. Pharmacol. (1993) 44:524-532.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 524-532
    • Linden, J.1    Taylor, H.E.2    Robeva, A.S.3
  • 155
    • 0029880945 scopus 로고    scopus 로고
    • 3. Adenosine receptor variant
    • SAJJADI FG, BOYLE DL, DOMINGO RC, FIRESTEIN GS: cDNA cloning and characterization of A3, an alternatively spliced rat A3 adenosine receptor variant. FEBS Lett. (1996) 382:125-129.
    • (1996) FEBS Lett. , vol.382 , pp. 125-129
    • Sajjadi, F.G.1    Boyle, D.L.2    Domingo, R.C.3    Firestein, G.S.4
  • 156
    • 17544383117 scopus 로고    scopus 로고
    • 3 adenosine receptor
    • PALMER TM, BENOVIC JL, STILES GL: Molecular basis for subtype-specific desentization of inhibitory adenosine receptors. Analysis of chimeric A1-A3 adenosine receptor. J. Biol. Chem. (1996) 271:15272-15278.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15272-15278
    • Palmer, T.M.1    Benovic, J.L.2    Stiles, G.L.3
  • 159
    • 0034616038 scopus 로고    scopus 로고
    • 3 adenosine receptor expressed in the brain?
    • RIVKEES SA, THEVANANTHER S, HAO H: Are A3 adenosine receptor expressed in the brain? NeuroRe-port (2000) 11:1025-1030.
    • (2000) NeuroRe-port , vol.11 , pp. 1025-1030
    • Rivkees, S.A.1    Thevananther, S.2    Hao, H.3
  • 161
    • 0029621016 scopus 로고
    • 3 adenosine receptors in rat brain
    • ABBRACCHIO MP, BRAMBILLA R, CERUTI S et al.: G-protein-dependent activationofphospholipaseCby A3 adenosine receptors in rat brain. Mol. Pharmacol. (1995) 48:1038-1045.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 1038-1045
    • Abbracchio, M.P.1    Brambilla, R.2    Ceruti, S.3
  • 162
    • 0034052190 scopus 로고    scopus 로고
    • 3 adenosine receptor ligands: History and perspectives
    • BARALDI PG, CACCIARI B, ROMAGNOLI R et al.: A3 adenosine receptor ligands: history and perspectives. Med. Res. Rev. (2000) 20:103-128.
    • (2000) Med. Res. Rev. , vol.20 , pp. 103-128
    • Baraldi, P.G.1    Cacciari, B.2    Romagnoli, R.3
  • 164
    • 0031012121 scopus 로고    scopus 로고
    • 1 receptor-mediated responses in rat hippocampus
    • DUNWIDDIE TV, DIAO L, KIM HO, JIANG JL, JACOBSON KA: Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus. J. Neurosci. (1997) 17:607-614.
    • (1997) J. Neurosci. , vol.17 , pp. 607-614
    • Dunwiddie, T.V.1    Diao, L.2    Kim, H.O.3    Jiang, J.L.4    Jacobson, K.A.5
  • 165
    • 0030694505 scopus 로고    scopus 로고
    • 3 adenosine receptor-selective antagonists
    • JACOBSON KA, PARK KS, JIANG JL et al.: Pharmacological characterization of novel A3 adenosine receptor-selective antagonists. Neuropharmacology (1997) 36:1157-1165.
    • (1997) Neuropharmacology , vol.36 , pp. 1157-1165
    • Jacobson, K.A.1    Park, K.S.2    Jiang, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.