Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals

Journal of Neurochemistry

Volumn 67, Issue 1, 1996, Pages 374-381

  Gubitz, Amelie K ^a   Widdowson, Leon ^a   Kurokawa, Masako ^a,b   Kirkpatrick, Karen A ^a   Richardson, Peter J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

A2a receptor antagonist; Acetylcholine; Adenosine A2a receptor; Gs protein linked receptor; KF17837; Signalling pathway

Indexed keywords

8 (3,4 DIMETHOXYSTYRYL) 7 METHYL 1,3 DIPROPYLXANTHINE; ADENOSINE A2 RECEPTOR; ADENYLATE CYCLASE; CALCIUM CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; CHOLINERGIC NERVE CELL; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; DRUG EFFECT; ENZYME ACTIVATION; GENETIC TRANSFECTION; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ACETYLCHOLINE; ADENOSINE; ALKALOIDS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZOPHENANTHRIDINES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CHOLERA TOXIN; CHOLINERGIC FIBERS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; FORSKOLIN; GTP-BINDING PROTEINS; ISOQUINOLINES; NEOSTRIATUM; NEURONS; PHENANTHRIDINES; PHENETHYLAMINES; PIPERAZINES; POTASSIUM; PRESYNAPTIC TERMINALS; PROTEIN KINASE C; PROTEIN KINASES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; SIGNAL TRANSDUCTION; SPIDER VENOMS; STEREOISOMERISM; SULFONAMIDES; TRITIUM; XANTHINES;

ANIMALIA;

EID: 0029977048     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67010374.x     Document Type: Article

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