Activation of adenosine A1 and A(2A) receptors modulates dopamine D2 receptor-induced responses in stably transfected human neuroblastoma cells

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 432-439

  Salim, Hassan ^a,b   Ferré, Sergi ^c,d   Dalal, Abderrahim ^b   Peterfreund, Robert A ^e   Fuxe, Kjell ^c   Vincent, Jean Didier ^a   Lledo, Pierre Marie ^a  

^a CNRS   (France)

^b CADI AYYAD UNIVERSITY   (Morocco)

^c KAROLINSKA INSTITUTE   (Sweden)

^d INST D INVESTIGACIONS B   (Spain)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Adenosine deaminase; Adenosine receptors; Basal ganglia; Dopamine receptors; Intracellular calcium; Stable transfection

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE DEAMINASE; CALCIUM ION; DOPAMINE 2 RECEPTOR; ADENOSINE RECEPTOR; CALCIUM; DOPAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT;

ARTICLE; BASAL GANGLION; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROMODULATION; PRIORITY JOURNAL; TUMOR CELL LINE; BINDING COMPETITION; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GENETIC TRANSFECTION; METABOLISM; NEUROBLASTOMA; PATHOLOGY; PHYSIOLOGY;

ADENOSINE; ADENOSINE DEAMINASE; BINDING, COMPETITIVE; CALCIUM; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; HUMANS; NEUROBLASTOMA; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE D2; RECEPTORS, PURINERGIC P1; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033621564     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740432.x     Document Type: Article

References (33)

1. Alexander S. P. and Reddington M. (1989) The cellular localization of adenosine receptors in rat neostriatum. Neuroscience 28, 645-651.
2. Anwyl R. (1991) Modulation of venebrate neuronal calcium channels by transmitters. Brain Res. Brain Res. Rev. 16, 265-281.
3. Cardinaud B., Gilbert J.-M., Liu F., Sugamori K., Vincent J.-D., Niznik H. B., and Vernier P. (1998) Evolution and origin of the diversity of dopamine receptors in vertebrates. Adv. Pharmacol. 42, 936-940.
4. Dasgupta S., Ferré S., Kull B., Hedlund P. B., Finnman U. B., Ahlberg S., Arenas E., Fredholm B. B., and Fuxe K. (1996) Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells. Eur. J. Pharmacol. 316, 325-331.
5. Dixon A. K., Gubitz A. K., Sirinathsinghji D. J., Richardson P. J., and Freeman T. C. (1996) Tissue distribution of adenosine receptor mRNAs in the rat. Br. J. Pharmacol. 118, 1461-1468.
6. Dolphin A. C. (1990) G protein modulation of calcium currents in neurons. Annu. Rev. Physiol. 52, 243-255.
7. Farooqui S. M. (1994) Induction of adenylate cyclase sensitive dopamine D2-receptors in retinoic acid induced differentiated human neuroblastoma SH-SY5Y cells. Life Sci. 55, 1887-1893.
8. Ferré S., Rubio A., and Fuxe K. (1991a) Stimulation of adenosine A2 receptors induces catalepsy. Neurosci. Lett. 130, 162-164.
9. Ferré S., von Euler G., Johansson B., Fredholm B. B., and Fuxe K. (1991b) Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc. Natl. Acad. Sci. USA 88, 7238-7241.
10. Ferré S., Fuxe K., von Euler G., Johansson B., and Fredholm B. B. (1992) Adenosine-dopamine interactions in the brain. Neuroscience 51, 501-512.
11. Ferré S., O'Connor W. T., Fuxe K., and Ungerstedt U. (1993a) The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain. J. Neurosci. 12, 5402-5406.
12. Ferré S., Snaprud P., and Fuxe K. (1993b) Opposing actions of an adenosine A2 receptor agonist and a GTP analogue on the regulation of dopamine D2 receptors in rat neostriatal membranes. Eur. J. Pharmacol. 244, 311-315.
13. Ferré S., O'Connor W. T., Snaprud P., Ungerstedt U., and Fuxe K. (1994) Antagonistic interaction between adenosine A2A receptors and dopamine D2 receptors in the ventral striopallidal system. Implications for the treatment of schizophrenia. Neuroscience 63, 765-773.
14. Ferré S., Fredholm B. B., Morelli M., Popoli P., and Fuxe K. (1997) Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci. 20, 482-487.
15. Fredholm B. B., Johansson B., Van der Ploeg J., Hu P. S., and Jin S. (1993) Neuromodulatory roles of purines. Drug Dev. Res. 28, 349-353.
16. Fredholm B. B., Abbracchio M. P., Burnstock G., Daly J. W., Harden T. K., Jacohson K. A., Leff P., and Williams M. (1994) Nomenclature and classification of purinoceptors. Pharmacol. Rev. 46, 143-156.
17. Fuxe K., Ferre S., Zoli M., and Agnati L. F. (1998) Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A2A/dopamine D1 receptor interactions in the basal ganglia. Brain Res. Brain Res. Rev. 26, 258-273.
18. Gingrich J. A. and Caron M. G. (1993) Recent advances in the molecular biology of dopamine receptors. Annu. Rev. Neurosci. 16, 299-321.
19. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
20. Latini S., Pazzagli M., Pepeu G., and Pedata F. (1996) A2 adenosine receptors: their presence and neuromodulatory role in the central nervous system. Gen. Pharmacol. 27, 925-933.
21. 3H]quinpirole binding to dopaminergic receptors by adenosine A2A receptors. Neurosci. Lett. 239, 61-64.
22. Maytield D. R., Larson G., Orona R. A., and Zahniser N. R. (1996) Opposing actions of adenosine A2A and dopamine D2 receptor activation on GABA release in the basal ganglia: evidence for an A2A/D2 receptor interaction in globus pallidus. Synapse 22, 132-138.
23. Missale C., Nash S. R., Robinson S. W., Jaber M., and Caron M. G. (1998) Dopamine receptors: from structure to function. Physiol. Rev. 78, 189-225.
24. 1 adenosine receptor mRNA levels in SH-SY5Y cells. Soc. Neurosci. Abstr. 22, 1569.
25. 2A receptor mRNA expression in SH-SY5Y cells. Eur. J. Pharmacol. 336, 71-80.
26. Pollack A. E. and Fink J. S. (1995) Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway. Neuroscience 68, 721-728.
27. Reeve H. L., Vaughan P. F., and Peers C. (1994) Calcium channel currents in undifferentiated human neuroblastoma (SH-SY5Y) cells: actions and possible interactions of dihydropyridines and omega-conotoxin. Eur. J. Neurosci. 6, 943-952.
28. Rimondini R., Ferre S., Gimenez-Llort L., Ogren S. O., and Fuxe K. (1998) Differential effects of selective adenosine A1 and A2A receptor agonists on dopamine receptor agonist-induced behavioral responses in rats. Eur. J. Pharmacol. 347, 153-158.
29. 2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: an in situ hybridization histochemistry study. J. Neurochem. 57, 1062-1067.
30. Stefani A., Pisani A., Mercuri N. B., and Calabresi P. (1996) The modulation of calcium currents by the activation of mGluRs. Functional implications. Mol. Neurobiol. 13, 81-95.
31. Yang S. N., Dasgupta S., Lledo P.-M., Vincent J.-D., and Fuxe K. (1995) Reduction of dopamine D2 receptor transduction by activation of adenosine A2A receptors in stably A2A/D2 (long-form) receptor co-transfected mouse fibroblast cell lines: studies on intracellular calcium levels. Neuroscience 68, 729-736.
32. 1 adenosine receptors. J. Neurochem. 69, 2546-2554.
33. Zoli M., Agnati L. F., Hedlund P. B., Li X. M., Ferre S., and Fuxe K. (1993) Receptor-receptor interactions as an integrative mechanism in nerve cells. Mol. Neurobiol. 7, 293-334.