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Volumn 26, Issue 11, 2004, Pages 1164-1174

Chromosome rearrangements resulting from telomere dysfunction and their role in cancer

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENESIS; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; HUMAN; MARKER GENE; NONHUMAN; REVIEW; SISTER CHROMATID; TELOMERE;

EID: 8844224076     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.20125     Document Type: Review
Times cited : (135)

References (107)
  • 2
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn EH. 2001. Switching and signaling at the telomere. Cell 106:661-673.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 3
    • 0003893137 scopus 로고
    • Plainview, NY: Cold Spring Harbor Laboratory Press
    • Blackburn EH, Greider CW, editors. Telomeres. Plainview, NY: Cold Spring Harbor Laboratory Press, 1995.
    • (1995) Telomeres
    • Blackburn, E.H.1    Greider, C.W.2
  • 4
    • 0002309826 scopus 로고
    • Telomere dynamics and genome instability in human cancer
    • Blackburn EH, Greider CW, editors. Plainview, NY: Cold Spring Harbor Press
    • de Lange T. 1995. Telomere dynamics and genome instability in human cancer. In: Blackburn EH, Greider CW, editors. Telomeres. Plainview, NY: Cold Spring Harbor Press, pp. 265-293.
    • (1995) Telomeres , pp. 265-293
    • De Lange, T.1
  • 5
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • Karlseder J, Smogorzewska A, de Lange T. 2002. Senescence induced by altered telomere state, not telomere loss. Science 295:2446-2449.
    • (2002) Science , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    De Lange, T.3
  • 6
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, et al. 1992. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921-1929.
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5
  • 7
    • 0033595174 scopus 로고    scopus 로고
    • Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process
    • Ducray C, Pommier J-P, Martins L, Boussin F, Sabatier L. 1999. Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process. Oncogene 18:4211-4223.
    • (1999) Oncogene , vol.18 , pp. 4211-4223
    • Ducray, C.1    Pommier, J.-P.2    Martins, L.3    Boussin, F.4    Sabatier, L.5
  • 8
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov SR, Kozakiewicz BK, Hoist CR, Stampfer MR, Haupt LM, et al. 2001. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 409:633-637.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozakiewicz, B.K.2    Hoist, C.R.3    Stampfer, M.R.4    Haupt, L.M.5
  • 9
    • 0036829333 scopus 로고    scopus 로고
    • Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells
    • Yaswen P, Stampfer MR. 2002. Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells. Int J Biochem Cell Biol 34:1382-1394.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1382-1394
    • Yaswen, P.1    Stampfer, M.R.2
  • 10
    • 0001934324 scopus 로고
    • Telomeres and aging
    • Blackburn EH, Greider CW, editors. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
    • Harley CB. 1995. Telomeres and aging. In: Blackburn EH, Greider CW, editors. Telomeres, Cold Spring Harbor: Cold Spring Harbor Laboratory Press, pp. 247-263.
    • (1995) Telomeres , pp. 247-263
    • Harley, C.B.1
  • 11
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu C-P, et al. 1998. Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352.
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Ouellette, M.2    Frolkis, M.3    Holt, S.E.4    Chiu, C.-P.5
  • 13
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. 1995. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 14:4240-4248.
    • (1995) EMBO J , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 15
    • 0029991014 scopus 로고    scopus 로고
    • Telomerase activity in human cancer
    • Shay JW, Wright WE. 1996. Telomerase activity in human cancer. Curr Opin Oncol 8:66-71.
    • (1996) Curr Opin Oncol , vol.8 , pp. 66-71
    • Shay, J.W.1    Wright, W.E.2
  • 16
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, et al. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3    Harley, C.B.4    West, M.D.5
  • 17
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR. 1997. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3:1271-1274.
    • (1997) Nat Med , vol.3 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 19
    • 0035940501 scopus 로고    scopus 로고
    • Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors
    • Gisselsson D, Jonson T, Petersen A, Strombeck B, Dal Cin P, et al. 2001. Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98:12683-12688.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12683-12688
    • Gisselsson, D.1    Jonson, T.2    Petersen, A.3    Strombeck, B.4    Dal Cin, P.5
  • 21
    • 0034490072 scopus 로고    scopus 로고
    • The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line
    • Fouladi B, Miller D, Sabatier L, Murnane JP. 2000. The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line. Neoplasia 2:540-554.
    • (2000) Neoplasia , vol.2 , pp. 540-554
    • Fouladi, B.1    Miller, D.2    Sabatier, L.3    Murnane, J.P.4
  • 22
    • 0036858415 scopus 로고    scopus 로고
    • DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
    • Lo AWI, Sabatier L, Fouladi B, Pottier G, Ricoul M, et al. 2002. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 6:531-538.
    • (2002) Neoplasia , vol.6 , pp. 531-538
    • Lo, A.W.I.1    Sabatier, L.2    Fouladi, B.3    Pottier, G.4    Ricoul, M.5
  • 23
    • 0034978564 scopus 로고    scopus 로고
    • Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
    • Rudolph KL, Millard M, Bosenberg MW, DePinho RA. 2001. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 28:155-159.
    • (2001) Nat Genet , vol.28 , pp. 155-159
    • Rudolph, K.L.1    Millard, M.2    Bosenberg, M.W.3    DePinho, R.A.4
  • 24
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi SE, Chang S, Lee S-L, Alson S, Gottlieb GJ, et al. 2000. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406:641-645.
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.-L.3    Alson, S.4    Gottlieb, G.J.5
  • 25
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. 1976. The clonal evolution of tumor cell populations. Science 194:23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 26
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb LA. 1992. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51:3075-3079.
    • (1992) Cancer Res , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 27
    • 0031060365 scopus 로고    scopus 로고
    • Genomic instability and its role in neoplasia
    • Tlsty TD. 1997. Genomic instability and its role in neoplasia. Curr Topics Microbiol Immunol 221:37-46.
    • (1997) Curr Topics Microbiol Immunol , vol.221 , pp. 37-46
    • Tlsty, T.D.1
  • 28
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B. 1998. Genetic instabilities in human cancers. Nature 396:643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 29
    • 0001294157 scopus 로고
    • The stability of broken ends of chromosomes in Zea mays
    • McClintock B. 1941. The stability of broken ends of chromosomes in Zea mays. Genetics 41:234-282.
    • (1941) Genetics , vol.41 , pp. 234-282
    • McClintock, B.1
  • 30
    • 0032823534 scopus 로고    scopus 로고
    • Oncogene amplification in solid tumors
    • Schwab M. 1999. Oncogene amplification in solid tumors. Sem Cancer Biol 9:319-325.
    • (1999) Sem Cancer Biol , vol.9 , pp. 319-325
    • Schwab, M.1
  • 31
    • 0002011265 scopus 로고    scopus 로고
    • Gene amplification in human cancers: Biological and clinical significance
    • Vogelstein B, Kinzler KW, editors. New York: McGraw-Hill
    • Brodeur GM, Hogarety MD. 1998. Gene amplification in human cancers: biological and clinical significance. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGraw-Hill. pp. 161-172.
    • (1998) The Genetic Basis of Human Cancer , pp. 161-172
    • Brodeur, G.M.1    Hogarety, M.D.2
  • 32
    • 0027152244 scopus 로고
    • Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells
    • Ma C, Martin S, Trask B, Hamlin JL. 1993. Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells. Genes Dev 7:605-620.
    • (1993) Genes Dev , vol.7 , pp. 605-620
    • Ma, C.1    Martin, S.2    Trask, B.3    Hamlin, J.L.4
  • 33
    • 0025666436 scopus 로고
    • Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells
    • Smith KA, Gorman PA, Stark MB, Graves RP, Stark GR. 1990. Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells. Cell 63:1219-1227.
    • (1990) Cell , vol.63 , pp. 1219-1227
    • Smith, K.A.1    Gorman, P.A.2    Stark, M.B.3    Graves, R.P.4    Stark, G.R.5
  • 34
    • 0000930196 scopus 로고
    • The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells
    • Toledo F, Buttin G, Debatisse M. 1993. The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells. Curr Biol 3:255-264.
    • (1993) Curr Biol , vol.3 , pp. 255-264
    • Toledo, F.1    Buttin, G.2    Debatisse, M.3
  • 35
    • 0030904279 scopus 로고    scopus 로고
    • Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets bounderies to early amplification
    • Coquelle A, Pipiras E, Toledo F, Buttin G, Debatisse M. 1997. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets bounderies to early amplification. Cell 89:215-225.
    • (1997) Cell , vol.89 , pp. 215-225
    • Coquelle, A.1    Pipiras, E.2    Toledo, F.3    Buttin, G.4    Debatisse, M.5
  • 36
    • 0027631352 scopus 로고
    • Molecular biology of double-minute chromosomes
    • Hahn PJ. 1993. Molecular biology of double-minute chromosomes. BioEssays 15:477-484.
    • (1993) BioEssays , vol.15 , pp. 477-484
    • Hahn, P.J.1
  • 37
    • 0036272490 scopus 로고    scopus 로고
    • Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells
    • Lo AWI, Sprung CN, Fouladi B, Pedram M, Sabatier L, et al. 2002. Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. Mol Cell Biol 22:4836-4850.
    • (2002) Mol Cell Biol , vol.22 , pp. 4836-4850
    • Lo, A.W.I.1    Sprung, C.N.2    Fouladi, B.3    Pedram, M.4    Sabatier, L.5
  • 38
    • 0033625440 scopus 로고    scopus 로고
    • A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q23 amplification
    • Shuster MI, Man L, Le Beau MM, Davis E, Sawicki M, et al. 2000. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q23 amplification. Genes Chrom Cancer 28:153-163.
    • (2000) Genes Chrom Cancer , vol.28 , pp. 153-163
    • Shuster, M.I.1    Man, L.2    Le Beau, M.M.3    Davis, E.4    Sawicki, M.5
  • 39
  • 40
    • 0034608950 scopus 로고    scopus 로고
    • Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks
    • Singer MJ, Mesner LD, Friedman CL, Trask BJ, Hamlin JL. 2000. Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks. Proc Natl Acad Sci USA 97:7921-7926.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7921-7926
    • Singer, M.J.1    Mesner, L.D.2    Friedman, C.L.3    Trask, B.J.4    Hamlin, J.L.5
  • 41
    • 0642336728 scopus 로고    scopus 로고
    • Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies
    • Montgomery E, Wilentz RE, Argani P. 2003. Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies. Cancer Biol Ther 2:248-252.
    • (2003) Cancer Biol Ther , vol.2 , pp. 248-252
    • Montgomery, E.1    Wilentz, R.E.2    Argani, P.3
  • 42
    • 0037206935 scopus 로고    scopus 로고
    • Induction of multiple double-strand breaks within an hsr by meganuclease I-Scel expression of fragile site activation leads to formation of double minutes and other chromosomal rearrangements
    • Coquelle A, Rozier L, Dutrillaux B, Debatisse M. 2002. Induction of multiple double-strand breaks within an hsr by meganuclease I-Scel expression of fragile site activation leads to formation of double minutes and other chromosomal rearrangements. Oncogene 21:7671-7679.
    • (2002) Oncogene , vol.21 , pp. 7671-7679
    • Coquelle, A.1    Rozier, L.2    Dutrillaux, B.3    Debatisse, M.4
  • 43
    • 0032132806 scopus 로고    scopus 로고
    • A new role for hypoxia in tumor progression: Induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs
    • Coquelle A, Toledo F, Stern S, Bieth A, Debatisse M. 1998. A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs. Mol Cell 2:249-265.
    • (1998) Mol Cell , vol.2 , pp. 249-265
    • Coquelle, A.1    Toledo, F.2    Stern, S.3    Bieth, A.4    Debatisse, M.5
  • 44
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska A, de Lange T. 2004. Regulation of telomerase by telomeric proteins. Annu Rev Biochem 73:177-208.
    • (2004) Annu Rev Biochem , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 45
    • 2042534735 scopus 로고    scopus 로고
    • Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
    • Teixeira MT, Arneric M, Sperisen P, Lingner J. 2004. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117:323-335.
    • (2004) Cell , vol.117 , pp. 323-335
    • Teixeira, M.T.1    Arneric, M.2    Sperisen, P.3    Lingner, J.4
  • 46
    • 0035313820 scopus 로고    scopus 로고
    • Telomeric chromatin: Replicating and wrapping up chromosome ends
    • Shore D. 2001. Telomeric chromatin: replicating and wrapping up chromosome ends. Curr Op Genet Dev 11:189-198.
    • (2001) Curr Op Genet Dev , vol.11 , pp. 189-198
    • Shore, D.1
  • 47
    • 0035152978 scopus 로고    scopus 로고
    • TP53-dependent chromosome instability is associated with transient reductions in telomere length in immortal telomerase-positive cell lines
    • Schwartz JL, Jordan R, Liber H, Murnane JP, Evans HH. 2001. TP53-dependent chromosome instability is associated with transient reductions in telomere length in immortal telomerase-positive cell lines. Genes Chrom Cancer 30:236-244.
    • (2001) Genes Chrom Cancer , vol.30 , pp. 236-244
    • Schwartz, J.L.1    Jordan, R.2    Liber, H.3    Murnane, J.P.4    Evans, H.H.5
  • 48
    • 0031869107 scopus 로고    scopus 로고
    • Telomere length dynamics in telomerase-positive immortal human cell populations
    • Bryan TM, Englezou A, Dunham MA, Reddel RR. 1998. Telomere length dynamics in telomerase-positive immortal human cell populations. Exp Cell Res 239:370-378.
    • (1998) Exp Cell Res , vol.239 , pp. 370-378
    • Bryan, T.M.1    Englezou, A.2    Dunham, M.A.3    Reddel, R.R.4
  • 49
    • 0033592950 scopus 로고    scopus 로고
    • DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes
    • Bailey SM, Meyne J, Chen DJ, Kurimasa A, Li GC, et al. 1999. DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes. Proc Natl Acad Sci USA 96:14899-14904.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14899-14904
    • Bailey, S.M.1    Meyne, J.2    Chen, D.J.3    Kurimasa, A.4    Li, G.C.5
  • 51
    • 0036566036 scopus 로고    scopus 로고
    • Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
    • Espejel S, Franco S, Rodriguez-Perales S, Souffler SD, Cigudosa JC, et al. 2002. Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres. EMBO J 21:2207-2219.
    • (2002) EMBO J , vol.21 , pp. 2207-2219
    • Espejel, S.1    Franco, S.2    Rodriguez-Perales, S.3    Souffler, S.D.4    Cigudosa, J.C.5
  • 52
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
    • Zhu X-D, Kuster B, Mann M, Petrini JHJ, de Lange T. 2000. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet 25:347-352.
    • (2000) Nat Genet , vol.25 , pp. 347-352
    • Zhu, X.-D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.J.4    De Lange, T.5
  • 53
    • 0035954284 scopus 로고    scopus 로고
    • Rescue of a telomere length defect in Nijmegen breakage syndrome cells requires NBS and the telomerase catalytic subunit
    • Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, et al. 2001. Rescue of a telomere length defect in Nijmegen breakage syndrome cells requires NBS and the telomerase catalytic subunit. Curr Biol 11:962-966.
    • (2001) Curr Biol , vol.11 , pp. 962-966
    • Ranganathan, V.1    Heine, W.F.2    Ciccone, D.N.3    Rudolph, K.L.4    Wu, X.5
  • 54
    • 0347990555 scopus 로고    scopus 로고
    • Telomere instability in a human tumor cell line expressing the NBS1 gene with mutations at sites phosphorylated by the ATM protein
    • Bai Y, Murnane JP. 2003. Telomere instability in a human tumor cell line expressing the NBS1 gene with mutations at sites phosphorylated by the ATM protein. Mol Can Res 1:1058-1069.
    • (2003) Mol Can Res , vol.1 , pp. 1058-1069
    • Bai, Y.1    Murnane, J.P.2
  • 55
    • 0041324850 scopus 로고    scopus 로고
    • Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein
    • Bai Y, Murnane JP. 2003. Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein. Hum Genet 113:337-347.
    • (2003) Hum Genet , vol.113 , pp. 337-347
    • Bai, Y.1    Murnane, J.P.2
  • 56
    • 0036606186 scopus 로고    scopus 로고
    • Saccharomyces Rrm3p, a 5′' to 3′' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA
    • Ivessa AS, Zhou J-Q, Schulz VP, Monson EK, Zakian VA. 2002. Saccharomyces Rrm3p, a 5′' to 3′' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. Genes Dev 16:1383-1396.
    • (2002) Genes Dev , vol.16 , pp. 1383-1396
    • Ivessa, A.S.1    Zhou, J.-Q.2    Schulz, V.P.3    Monson, E.K.4    Zakian, V.A.5
  • 57
    • 0348047594 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes
    • Ivessa AS, Lenzmeier BA, Bessler JB, Goudsouzian LK, Schnakenberg SL, et al. 2003. The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes. Molec Cell 12:1525-1536.
    • (2003) Molec Cell , vol.12 , pp. 1525-1536
    • Ivessa, A.S.1    Lenzmeier, B.A.2    Bessler, J.B.3    Goudsouzian, L.K.4    Schnakenberg, S.L.5
  • 58
    • 0037427471 scopus 로고    scopus 로고
    • Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast
    • Ricchetti M, Dujon B, Fairhead C. 2003. Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast. J Mol Biol 328:847-862.
    • (2003) J Mol Biol , vol.328 , pp. 847-862
    • Ricchetti, M.1    Dujon, B.2    Fairhead, C.3
  • 59
    • 0031821009 scopus 로고    scopus 로고
    • Preferential accumulation of single-stranded regions in telomeres of human fibroblasts
    • Petersen S, Saretzki G, von Zglinicki T. 1998. Preferential accumulation of single-stranded regions in telomeres of human fibroblasts. Exp Cell Res 239:152-160.
    • (1998) Exp Cell Res , vol.239 , pp. 152-160
    • Petersen, S.1    Saretzki, G.2    Von Zglinicki, T.3
  • 60
  • 61
    • 0033616762 scopus 로고    scopus 로고
    • Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
    • Zhu J, Wang H, Bishop JM, Blackburn EH. 1999. Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc Natl Acad Sci USA 96:3723-3728.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3723-3728
    • Zhu, J.1    Wang, H.2    Bishop, J.M.3    Blackburn, E.H.4
  • 62
    • 0043199578 scopus 로고    scopus 로고
    • Telomerase maintains telomere structure in normal human cells
    • Masutomi K, Yu EY, Kurts S, Ben-Porath I, Rurrier JL, et al. 2003. Telomerase maintains telomere structure in normal human cells. Cell 114:241-253.
    • (2003) Cell , vol.114 , pp. 241-253
    • Masutomi, K.1    Yu, E.Y.2    Kurts, S.3    Ben-Porath, I.4    Rurrier, J.L.5
  • 63
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B, Smogorzewska A, de Lange T. 1998. TRF2 protects human telomeres from end-to-end fusions. Cell 92:401-413.
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 64
    • 0034437666 scopus 로고    scopus 로고
    • A new connection at human telomeres: Association of the Mre11 complex with TRF2
    • de Lange T, Petrini JHJ. 2000. A new connection at human telomeres: association of the Mre11 complex with TRF2. Cold Spring Harbor Symp Quant Biol 65:265-273.
    • (2000) Cold Spring Harbor Symp Quant Biol , vol.65 , pp. 265-273
    • De Lange, T.1    Petrini, J.H.J.2
  • 65
    • 0037175018 scopus 로고    scopus 로고
    • Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
    • Opresko PL, von Kobbe C, Laine J-P, Harrigan J, Hickson ID, et al. 2002. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J Biol Chem 277:41110-41119.
    • (2002) J Biol Chem , vol.277 , pp. 41110-41119
    • Opresko, P.L.1    Von Kobbe, C.2    Laine, J.-P.3    Harrigan, J.4    Hickson, I.D.5
  • 66
    • 0026037255 scopus 로고
    • Developmentally programmed healing of chromosomes by telomerase in Tetrahymena
    • Yu G, Blackburn EH. 1991. Developmentally programmed healing of chromosomes by telomerase in Tetrahymena. Cell 67:823-832.
    • (1991) Cell , vol.67 , pp. 823-832
    • Yu, G.1    Blackburn, E.H.2
  • 67
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerase a and d
    • Diede SJ, Gottschling DE. 1999. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerase a and d. Cell 99:723-733.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 68
    • 0033838428 scopus 로고    scopus 로고
    • Characterization of terminal deletions at 7q32 and 22q 13.3 healed by de novo telomere addition
    • Varley H, Di S, Scherer SW, Royle NJ. 2000. Characterization of terminal deletions at 7q32 and 22q 13.3 healed by de novo telomere addition. Am J Hum Genet 67:610-622.
    • (2000) Am J Hum Genet , vol.67 , pp. 610-622
    • Varley, H.1    Di, S.2    Scherer, S.W.3    Royle, N.J.4
  • 69
    • 0031020786 scopus 로고    scopus 로고
    • Molecular characterization of a 130-kb terminal microdeletion at 22q in a child with mild mental retardation
    • Wong AC, Ning Y, Flint J, Clark K, Dumanski JP, et al. 1997. Molecular characterization of a 130-kb terminal microdeletion at 22q in a child with mild mental retardation. Am J Hum Genet 60:113-120.
    • (1997) Am J Hum Genet , vol.60 , pp. 113-120
    • Wong, A.C.1    Ning, Y.2    Flint, J.3    Clark, K.4    Dumanski, J.P.5
  • 70
    • 0031029805 scopus 로고    scopus 로고
    • The relationship between chromosome structure and function at a human telomeric region
    • Flint J, Thomas K, Micklem G, Raynham H, Clark K, et al. 1997. The relationship between chromosome structure and function at a human telomeric region. Nat Genet 15:252-257.
    • (1997) Nat Genet , vol.15 , pp. 252-257
    • Flint, J.1    Thomas, K.2    Micklem, G.3    Raynham, H.4    Clark, K.5
  • 72
    • 0025808098 scopus 로고
    • Recognition of a chromosome truncation site associated with a-thalassaimia by human telomerase
    • Morin GB. 1991. Recognition of a chromosome truncation site associated with a-thalassaimia by human telomerase. Nature 353:454-456.
    • (1991) Nature , vol.353 , pp. 454-456
    • Morin, G.B.1
  • 73
    • 0027325817 scopus 로고
    • Telomere capture stabilizes chromosome breakage
    • Meltzer PS, Guan X-Y, Trent JM. 1993. Telomere capture stabilizes chromosome breakage. Nat Genet 4:252-255.
    • (1993) Nat Genet , vol.4 , pp. 252-255
    • Meltzer, P.S.1    Guan, X.-Y.2    Trent, J.M.3
  • 74
    • 0035839132 scopus 로고    scopus 로고
    • Telomere dysfunction increases mutation rates and genomic instability
    • Hackett JA, Feldser DM, Greider CW. 2001. Telomere dysfunction increases mutation rates and genomic instability. Cell 106:275-286.
    • (2001) Cell , vol.106 , pp. 275-286
    • Hackett, J.A.1    Feldser, D.M.2    Greider, C.W.3
  • 75
    • 0031737723 scopus 로고    scopus 로고
    • Chromosome break-induced replication leads to nonreciprocal translocations and telomere capture
    • Bosco G, Haber JE. 1998. Chromosome break-induced replication leads to nonreciprocal translocations and telomere capture. Genetics 150:1037-1047.
    • (1998) Genetics , vol.150 , pp. 1037-1047
    • Bosco, G.1    Haber, J.E.2
  • 76
    • 0141483485 scopus 로고    scopus 로고
    • Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats
    • Sadaie M, Naito T, Ishikawa F. 2003. Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats. Genes Dev 17:2271-2282.
    • (2003) Genes Dev , vol.17 , pp. 2271-2282
    • Sadaie, M.1    Naito, T.2    Ishikawa, F.3
  • 77
    • 0042320679 scopus 로고    scopus 로고
    • A series of supernumerary small ring marker autosomes identified by FISH with chromosome probe arrays and literature review excluding chromosome 15
    • Daniel A, Malafiej P. 2003. A series of supernumerary small ring marker autosomes identified by FISH with chromosome probe arrays and literature review excluding chromosome 15. Am J Med Genet 117:212-222.
    • (2003) Am J Med Genet , vol.117 , pp. 212-222
    • Daniel, A.1    Malafiej, P.2
  • 78
    • 0030220770 scopus 로고    scopus 로고
    • Telomeric associations in the progression of chromosome aberrations in pediatric solid tumors
    • Sawyer JR, Roloson GJ, Bell JM, Thomas JR, Teo C, et al. 1996. Telomeric associations in the progression of chromosome aberrations in pediatric solid tumors. Cancer Genet Cytogenet 90:1-13.
    • (1996) Cancer Genet Cytogenet , vol.90 , pp. 1-13
    • Sawyer, J.R.1    Roloson, G.J.2    Bell, J.M.3    Thomas, J.R.4    Teo, C.5
  • 79
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph KL, Chang S, Lee H-W, Blasco M, Gottlieb GJ, et al. 1999. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96:701-712.
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.-W.3    Blasco, M.4    Gottlieb, G.J.5
  • 80
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. 1990. Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 81
    • 0000146723 scopus 로고    scopus 로고
    • Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
    • Greenberg RA, Chin L, Femino A, Lee KH, Gottlieb GJ, et al. 1999. Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 97:515-525.
    • (1999) Cell , vol.97 , pp. 515-525
    • Greenberg, R.A.1    Chin, L.2    Femino, A.3    Lee, K.H.4    Gottlieb, G.J.5
  • 82
    • 0034612308 scopus 로고    scopus 로고
    • The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
    • Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, et al. 2000. The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc Natl Acad Sci USA 97:6630-6633.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6630-6633
    • Ferguson, D.O.1    Sekiguchi, J.M.2    Chang, S.3    Frank, K.M.4    Gao, Y.5
  • 83
    • 0035839840 scopus 로고    scopus 로고
    • DNA double strand break repair and chromosomal translocation: Lessons from animal models
    • Ferguson DO, Alt FW. 2001. DNA double strand break repair and chromosomal translocation: Lessons from animal models. Oncogene 20:5572-5579.
    • (2001) Oncogene , vol.20 , pp. 5572-5579
    • Ferguson, D.O.1    Alt, F.W.2
  • 84
    • 0034690249 scopus 로고    scopus 로고
    • Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic instability and development
    • Gao Y, Ferguson DO, Xie W, Manis JP, Sekiguchi J, et al. 2000. Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic instability and development. Nature 404:897-900.
    • (2000) Nature , vol.404 , pp. 897-900
    • Gao, Y.1    Ferguson, D.O.2    Xie, W.3    Manis, J.P.4    Sekiguchi, J.5
  • 85
    • 0034732239 scopus 로고    scopus 로고
    • DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
    • Difilippantonio MJ, Zhu J, Chen HT, Meffre E, Nussenzweig MC, et al. 2000. DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature 404:510-514.
    • (2000) Nature , vol.404 , pp. 510-514
    • Difilippantonio, M.J.1    Zhu, J.2    Chen, H.T.3    Meffre, E.4    Nussenzweig, M.C.5
  • 86
    • 0032821552 scopus 로고    scopus 로고
    • Molecular genetics of breast cancer progression
    • Ingvarsson S. 1999. Molecular genetics of breast cancer progression. Sem Cancer Biol 9:277-288.
    • (1999) Sem Cancer Biol , vol.9 , pp. 277-288
    • Ingvarsson, S.1
  • 87
    • 0028178792 scopus 로고
    • The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
    • Schulz VP, Zakian VA. 1994. The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 76:145-155.
    • (1994) Cell , vol.76 , pp. 145-155
    • Schulz, V.P.1    Zakian, V.A.2
  • 88
    • 0027140403 scopus 로고
    • New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats
    • Kramer KM, Haber JE. 1993. New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev 7:2345-2356.
    • (1993) Genes Dev , vol.7 , pp. 2345-2356
    • Kramer, K.M.1    Haber, J.E.2
  • 89
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in saccharomyces cerevisiae
    • Kolodner RD, Putnam CD, Myung K. 2002. Maintenance of genome stability in saccharomyces cerevisiae. Science 297:552-557.
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 90
    • 0018820482 scopus 로고
    • Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents
    • Murnane JP, Byfield JE, Ward JF, Calabro-Jones P. 1980. Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents. Nature 285:326-329.
    • (1980) Nature , vol.285 , pp. 326-329
    • Murnane, J.P.1    Byfield, J.E.2    Ward, J.F.3    Calabro-Jones, P.4
  • 91
    • 0242721689 scopus 로고    scopus 로고
    • End resection initiates genomic instability in the absence of telomerase
    • Hackett JA, Greider CW. 2003. End resection initiates genomic instability in the absence of telomerase. Mol Cell Biol 23:8450-8461.
    • (2003) Mol Cell Biol , vol.23 , pp. 8450-8461
    • Hackett, J.A.1    Greider, C.W.2
  • 92
    • 0033602035 scopus 로고    scopus 로고
    • Telomere dynamics in a human cancer cell line
    • Sprung CN, Sabatier L, Murnane JP. 1999. Telomere dynamics in a human cancer cell line. Exp Cell Res 247:29-37.
    • (1999) Exp Cell Res , vol.247 , pp. 29-37
    • Sprung, C.N.1    Sabatier, L.2    Murnane, J.P.3
  • 93
    • 0034856864 scopus 로고    scopus 로고
    • Capture of DNA sequences at double-strand breaks in mammalian cells
    • Lin Y, Waldman AS. 2001. Capture of DNA sequences at double-strand breaks in mammalian cells. Genetics 158:1665-1674.
    • (2001) Genetics , vol.158 , pp. 1665-1674
    • Lin, Y.1    Waldman, A.S.2
  • 94
    • 0031032549 scopus 로고    scopus 로고
    • Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
    • Sargent RG, Brenneman MA, Wilson JH. 1997. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol Cell Biol 17:267-277.
    • (1997) Mol Cell Biol , vol.17 , pp. 267-277
    • Sargent, R.G.1    Brenneman, M.A.2    Wilson, J.H.3
  • 95
    • 0032535036 scopus 로고    scopus 로고
    • Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations
    • Richardson C, Moynahan ME, Jasin M. 1998. Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev 12:3831-3842.
    • (1998) Genes Dev , vol.12 , pp. 3831-3842
    • Richardson, C.1    Moynahan, M.E.2    Jasin, M.3
  • 96
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • Johnson RD, Jasin M. 2000. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J 19:3398-3407.
    • (2000) EMBO J , vol.19 , pp. 3398-3407
    • Johnson, R.D.1    Jasin, M.2
  • 97
    • 0034621854 scopus 로고    scopus 로고
    • Frequent chromosomal translocations induced by DNA double-strand breaks
    • Richardson C, Jasin M. 2000. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 405:697-700.
    • (2000) Nature , vol.405 , pp. 697-700
    • Richardson, C.1    Jasin, M.2
  • 98
    • 0028061666 scopus 로고
    • Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease
    • Rouet P, Smih F, Jasin M. 1994. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol 14:8096-8106.
    • (1994) Mol Cell Biol , vol.14 , pp. 8096-8106
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 99
    • 0030837535 scopus 로고    scopus 로고
    • Palindrome resolution and recombination in the mammalian germ line
    • Akgun E, Zahn J, Baumes S, Brown G, Liang F, et al. 1997. Palindrome resolution and recombination in the mammalian germ line. Mol Cell Biol 17:5559-5570.
    • (1997) Mol Cell Biol , vol.17 , pp. 5559-5570
    • Akgun, E.1    Zahn, J.2    Baumes, S.3    Brown, G.4    Liang, F.5
  • 100
    • 0032759353 scopus 로고    scopus 로고
    • Long inverted repeats are an at-risk motif for recombination in mammalian cells
    • Waldman AS, Tran H, Goldsmith EC, Resnick MA. 1999. Long inverted repeats are an at-risk motif for recombination in mammalian cells. Genetics 153:1873-1883.
    • (1999) Genetics , vol.153 , pp. 1873-1883
    • Waldman, A.S.1    Tran, H.2    Goldsmith, E.C.3    Resnick, M.A.4
  • 101
    • 0034025077 scopus 로고    scopus 로고
    • Homologous and nonhomologous recombinatin resulting in deletion: Effects of p53 status, microhomology, and repetitive DNA length and orientation
    • Gebow D, Miselis N, Liber H. 2000. Homologous and nonhomologous recombinatin resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation. Mol Cell Biol 20:4028-4035.
    • (2000) Mol Cell Biol , vol.20 , pp. 4028-4035
    • Gebow, D.1    Miselis, N.2    Liber, H.3
  • 102
    • 0035338254 scopus 로고    scopus 로고
    • RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site
    • Malkova A, Signon L, Schaefer CB, Naylor ML, Theis JF, et al. 2001. RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev 15:1055-1060.
    • (2001) Genes Dev , vol.15 , pp. 1055-1060
    • Malkova, A.1    Signon, L.2    Schaefer, C.B.3    Naylor, M.L.4    Theis, J.F.5
  • 103
    • 0032959506 scopus 로고    scopus 로고
    • RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase
    • Le S, Moore JK, Haber JE, Greider CW. 1999. RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics 152:143-152.
    • (1999) Genetics , vol.152 , pp. 143-152
    • Le, S.1    Moore, J.K.2    Haber, J.E.3    Greider, C.W.4
  • 104
    • 0025330850 scopus 로고
    • Chromosomal destabilization during gene amplification
    • Ruiz J, Wahl GM. 1990. Chromosomal destabilization during gene amplification. Molecular and Cellular Biology 10:3056-3066.
    • (1990) Molecular and Cellular Biology , vol.10 , pp. 3056-3066
    • Ruiz, J.1    Wahl, G.M.2
  • 105
    • 0026018901 scopus 로고
    • A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration
    • Windle B, Draper BW, Yin Y, O'Gorman S, Wahl GM. 1991. A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes and Development 5:160-174.
    • (1991) Genes and Development , vol.5 , pp. 160-174
    • Windle, B.1    Draper, B.W.2    Yin, Y.3    O'Gorman, S.4    Wahl, G.M.5
  • 106
    • 0022474735 scopus 로고
    • Large inverted duplications are associated with gene amplification
    • Ford M, Fried M. 1986. Large inverted duplications are associated with gene amplification. Cell 45:425-430.
    • (1986) Cell , vol.45 , pp. 425-430
    • Ford, M.1    Fried, M.2
  • 107
    • 0037136318 scopus 로고    scopus 로고
    • Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification
    • Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, et al. 2002. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J Exp Med 196:469-480.
    • (2002) J Exp Med , vol.196 , pp. 469-480
    • Difilippantonio, M.J.1    Petersen, S.2    Chen, H.T.3    Johnson, R.4    Jasin, M.5


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