Palindrome resolution and recombination in the mammalian germ line

Molecular and Cellular Biology

Volumn 17, Issue 9, 1997, Pages 5559-5570

  Akgün, Ercan ^a,d   Zahn, Jeffrey ^a   Baumes, Susan ^a   Brown, Greg ^b   Liang, Feng ^a   Romanienko, Peter J ^a   Lewis, Susanna ^b,c   Jasin, Maria ^a  

^a Weill Cornell Medical Center   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PALINDROMIC DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DNA CONFORMATION; DNA REPAIR; GENE AMPLIFICATION; GENE REARRANGEMENT; GENETIC RECOMBINATION; GERM LINE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPERM; TRANSGENE;

ANIMALIA; MAMMALIA; PROKARYOTA;

EID: 0030837535     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.9.5559     Document Type: Article

References (51)

1. Ashley, C. T. and S. T. Warren. 1995. Trinucleotide repeat expansion and human disease. Annu. Rev. Genet. 29:703-728.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, K. Struhl, L. M. Albright, D. M. Coen, and A. Varki. 1995. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
3. Brinster, R. L., H. Y. Chen, M. Trumbauer, A. W. Senear, R. Warren, and R. D. Palmiter. 1981. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 27:223-231.
4. Canceill, D., and S. D. Ehrlich. 1996. Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli. Proc. Natl. Acad. Sci. USA 93:6647-6652.
5. Chen, X., S. V. S. Mariappan, P. Catasti, R. Ratliff, R. K. Moyzis, A. Laayoun, S. S. Smith, E. M. Bradbury, and G. Gupta. 1995. Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications. Proc. Natl. Acad. Sci. USA 92:5199-5203.
6. Cohen, S., D. Hassin, S. Karby, and S. Lavi. 1994. Hairpin structures are the primary amplification products: a novel mechanism for generation of inverted repeats during gene amplification. Mol. Cell. Biol. 14:7782-7791.
7. Collick, A., J. Drew, J. Penberth, P. Bois, J. Luckett, F. Scaerou, A. Jeffreys, and W. Reik. 1996. Instability of long inverted repeats within mouse transgenes. EMBO J. 15:1163-1171.
8. Collins, J. 1981. Instability of palindromic DNA in Escherichia coli. Cold Spring Harbor Symp. Quant. Biol. 45:409-416.
9. Connelly, J. C., and D. R. F. Leach. 1996. The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes Cells 1:285-291.
10. Dolganov, G. M., R. S. Maser, A. Novikov, L. Tosto, S. Chong, D. A. Bressan, and J. H. J. Petrini. 1996. Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol. Cell. Biol. 16:4832-4841.
11. Donis-Keller, H., et al. 1987. A genetic linkage map of the human genome. Cell 51:319-337.
12. Ehrlich, S. D. 1989. Illegitimate recombination in bacteria, p. 799-832. In D. E. Berg and M. M. Howe (ed.), Mobile DNA. American Society for Microbiology, Washington, D.C.
13. Fan, Q., F. Xu, and T. D. Petes. 1995. Meiosis-specific double-strand breaks at the HIS4 recombination hotspot in the yeast Saccharomyces cerevisiae: control in cis and trans. Mol. Cell. Biol. 15:1679-1688.
14. Ford, M., and M. Fried. 1986. Large inverted duplications are associated with gene amplification. Cell 45:425-430.
15. Gacy, A. M., G. Goellner, N. Juranic, S. Macura, and C. T. McMurray. 1995. Trinucleotide repeats that expand in human disease form hairpin structures in vitro. Cell 81:533-540.
16. Gordenin, D. A., K. S. Lobachev, N. P. Degtyareva, A. L. Malkova, E. Perkins, and M. A. Resnick. 1993. Inverted DNA repeats: a source of eukaryotic genomic instability. Mol. Cell. Biol. 13:5315-5322.
17. Hall, C. V., P. E. Jacob, G. M. Ringold, and F. Lee. 1983. Expression and regulation of Escherichia coli lacZ gene fusions in mammalian cells. J. Mol. Appl. Genet. 2:101-109.
18. Henderson, S. T., and T. D. Petes. 1993. Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae. Genetics 133:57-62.
19. Henthorn, P. A., D. L. Mager, T. H. J. Huisman, and O. Smithies. 1986. A gene deletion ending within a complex array of repeated sequences 3′ to the human β-globin gene cluster. Proc. Natl. Acad. SCi. USA 83:5194-5198.
20. Hogan, B., F. Costantini, and E. Lacy. 1986. Manipulating the mouse embryo. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
21. Jasin, M. Unpublished results.
22. Jasin, M., and P. Zalamea. 1992. Analysis of Escherichia coli β-galactosidase expression in transgenic mice by flow cytometry of sperm. Proc. Natl. Acad. Sci. USA 89:10681-10685.
23. Jeffreys, A. J., V. Wilson, and S. L. Thein. 1985. Hypervariable "minisatellite" regions in human DNA. Nature 314:67-73.
24. Johzhuka, K., and H. Ogawa. 1995. Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics 139:1521-1532.
25. Jones, C., L. Penny, T. Mattina, S. Yu, E. Baker, L. Voullaire, W. Y. Langdon, G. R. Sutherland, R. I. Richards, and A. Tunnacliffe. 1995. Association of a chromosome deletion syndrome with a fragile site within the protooncogene CBL2. Nature 376:145-149.
26. Kuzminov, A., E. Schabtach, and F. W. Stahl. 1994. χ sites in combination with RecA protein increase the survival of linear DNA in Escherichia coli by inactivating exoV activity of RecBCD nuclease. EMBO J. 13:2764-2776.
27. Leach, D. R. F. 1994. Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair. Bioessays 16:893-900.
28. Lewis, S. 1994. P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells. Proc. Natl. Acad. Sci. USA 91:1332-1336.
29. Lewis, S. M. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological and comparative analyses. Adv. Immunol. 56:27-150.
30. Liang, F., and M. Jasin. 1995. Studies on the influence of cytosine methylation on DNA recombination and end-joining in mammalian cells. J. Biol. Chem. 270:23838-23844.
31. Liang, F., P. J. Romanienko, D. T. Weaver, P. A. Jeggo, and M. Jasin. 1996. Chromosomal double-strand break repair in Ku80 deficient cells. Proc. Natl. Acad. Sci. USA 93:8929-8933.
32. Ma, C., S. Martin, B. Trask, and J. Hamlin. 1993. Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells. Genes Dev. 7:605-620.
33. Mizuuchi, K., M. Mizuuchi, and M. Gellert. 1982. Cruciform structures in palindromic DNA are favoured by DNA supercoiling. J. Mol. Biol. 156:229-243.
34. Moynahan, M. E., E. Akgün, and M. Jasin. 1996. A model for testing recombinogenic sequences in the mouse germline. Hum. Mol. Genet. 5:875-886.
35. Murti, J. R., M. Bumbulis, and J. C. Schimenti. 1992. High-frequency germ line gene conversion in transgenic mice. Mol. Cell. Biol. 12:2545-2552.
36. Nag, D. K., and T. D. Petes. 1991. Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. Genetics 129:669-673.
37. Peschon, J. J., R. R. Behringer, R. D. Palmiter, and R. L. Brinster. 1987. Spermatid-specific expression of protamine 1 in transgenic mice. Proc. Natl. Acad. Sci. USA 84:5316-5319.
38. Petrini, J. H. J., M. E. Walsh, C. DiMare, J. R. Korenberg, X.-N. Chen, and D. T. Weaver. 1995. Isolation and characterization of the human MRE11 homologue. Genomics 29:80-86.
39. Romrell, L. J., A. R. Bellve, and D. W. Fawcett. 1976. Separation of mouse spermatogenic cells by sedimentation velocity. Dev. Biol. 49:119-131.
40. Roth, D. B., and J. H. Wilson. 1988. Illegitimate recombination in mammalian cells, p. 621-653. In R. Kucherlapati and G. R. Smith (ed.), Genetic recombination. American Society for Microbiology, Washington, D.C.
41. Rouet, P., F. Smih, and M. Jasin. 1994. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol. Cell. Biol. 14:8096-8106.
42. Ruskin, B., and G. R. Fink. 1993. Mutations in POL1 increase the mitotic instability of tandem inverted repeats in Saccharomyces cerevisiae. Genetics 133:43-56.
43. Schimenti, J. Personal communication.
44. Sharples, G. J., and D. R. Leach. 1995. Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (Rad32) recombination and repair proteins of yeast. Mol. Microbiol. 17: 1215-1217.
45. Smith, G. R. 1988. Homologous recombination in procaryotes. Microbiol. Rev. 52:1-28.
46. Szostak, J. W., T. L. Orr-Weaver, R. J Rothstein, and F. W. Stahl. 1983. The double-strand-break repair model for recombination. Cell 33:25-35.
47. Thomas, B. J., and R. Rothstein. 1991. Sex, maps, and imprinting. Cell 64:1-3.
48. Toledo, F., D. LeRoscouet, G. Buttin, and M. Debatisse. 1992. Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification. EMBO J. 11:2665-2673.
49. Weaver, D. T., and M. L. DePamphilis. 1984. The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in vivo. J. Mol. Biol. 180:961-986.
50. Wu, T.-C., and M. Lichten. 1994. Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science 263:515-518.
51. Wu, T.-C., and M. Lichten. 1995. Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae. Genetics 140:55-66.