Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA

Genes and Development

Volumn 16, Issue 11, 2002, Pages 1383-1396

  Ivessa, Andreas S ^a   Zhou, Jin Qiu ^a,b   Schulz, Vince P ^a   Monson, Ellen K ^a   Zakian, Virginia A ^a  

^a PRINCETON UNIVERSITY   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Helicase; Replication; RRM3; Telomerase; Telomere; Yeast

Indexed keywords

FUNGAL DNA; FUNGAL PROTEIN; HELICASE; PROTEIN RRM3P; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; FUNGAL GENE; GENETIC CODE; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TELOMERE; X CHROMOSOME; Y CHROMOSOME;

ADENOSINE TRIPHOSPHATASES; ALLELES; CATALYSIS; CELL CYCLE; CHROMOSOMES; DNA; DNA HELICASES; DNA REPLICATION; MODELS, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERE; TIME FACTORS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS PHAGE 3A;

EID: 0036606186     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.982902     Document Type: Article

References (48)

1. Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae
2. The Pif1p sub-family of helicases: Region specific DNA helicases
3. Sir proteins, Rif proteins and Cdc13p bind Saccharomyces telomeres in vivo
4. The localization of replication origins on ARS plasmids in S. cerevisiae
5. The Saccharomyces cerevisiae chromosome III left telomere has a type X, but not a type Y′ ARS region
6. Organization of DNA sequences and replication origins at yeast telomeres
7. RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
8. The importance of repairing stalled replication forks
9. A yeast origin of replication is activated late in S phase
10. Dna2 mutants reveal interactions with DNA polymerase α and Ctf4, a Pol α accessory factor, and show that full Dna2 helicase activity is not essential for growth
11. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
12. Yeast Ku as a regulator of chromosomal DNA end structure
13. Spreading of transcriptional repressor SIR3 from telomeric heterochromatin
14. Subtelomeric regions of yeast chromosomes contain a 36 base-pair tandemly repeated sequence
15. The in vivo replication origin of the yeast 2μm plasmid
16. The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA
17. A gene with specific and global effects on recombination of sequences from tandemly repeated genes in Saccharomyces cerevisiae
18. PIF1 DNA helicase from Saccharomyces cerevisiae. Biochemical characterization of the enzyme
19. The distribution of the numbers of mutants in bacterial populations
20. Mitotic recombination among subtelomeric Y′ repeats in Saccharomyces cerevisiae
21. A mutant with a defect in telomere elongation leads to senescence in yeast
22. Repair of chromosome ends after telomere loss in Saccharomyces
23. Cell cycle restriction of telomere elongation
24. PriA-directed replication fork restart in Escherichia coli
25. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
26. Time of replication of yeast centromeres and telomeres
27. Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast
28. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
29. Analysis of replication origin function on Chromosome III of Saccharomyces cerevisiae
30. Elaboration of telomeres in yeast: Recognition and modification of termini from Oxytricha macronuclear DNA
31. Replication fork pausing and recombination or "gimme a break"
32. ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae
33. The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
34. RuvAB acts at arrested replication forks
35. Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis
36. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
37. Internal tracts of telomeric DNA act as silencers in Saccharomyces cerevisiae
38. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
39. Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP
40. The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
41. Unusual DNA sequences associated with the ends of yeast chromosomes
42. 1-3 tails occur sequentially in late S phase on a yeast linear plasmid
43. 1-3 tails late in S phase
44. Evidence for a new step in telomere maintenance
45. Extra telomeres, but not internal tracts of telomeric DNA, reduce transcriptional repression at Saccharomyces telomeres
46. Protein DNA interactions in soluble telosomes from Saccharomyces cerevisiae
47. Saccharomyces telomeres assume a non-nucleosomal chromatin structure
48. The Pif1p helicase, a catalytic inhibitor of telomerase lengthening of yeast telomeres