Allosteric modulators of metabotropic glutamate receptors: Lessons learnt from mGlu1, mGlu2 and mGlu5 potentiators and antagonists

Biochemical Society Transactions

Volumn 32, Issue 5, 2004, Pages 881-887

  Johnson, M P ^a   Nisenbaum, E S ^a   Large, T H ^a   Emkey, R ^a   Baez, M ^a   Kingston, A E ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

3H IPTE; 35S GTP S autoradiography; Allosteric modulator; LY487379; Metabotropic glutamate (mGlu); Potentiator

Indexed keywords

4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; 4 CARBOXY 2 METHYLPHENYLGLYCINE; BAY 36720; EGLUMETAD; GLUTAMIC ACID; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LY 487379; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; R 214127; ROCHE 675523; SULFUR 35; UNCLASSIFIED DRUG;

ALLOSTERISM; AUTORADIOGRAPHY; BRAIN SLICE; CONFERENCE PAPER; EXCITATORY POSTSYNAPTIC POTENTIAL; NEUROTRANSMITTER RELEASE; PATCH CLAMP; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANIMALS; BINDING SITES; BRAIN; DRUG DESIGN; ELECTROPHYSIOLOGY; HUMANS; LIGANDS; MICE; MODELS, CHEMICAL; NEURONS; PROTEIN BINDING; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 8744227147     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0320881     Document Type: Conference Paper

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