메뉴 건너뛰기




Volumn 13, Issue 2, 1999, Pages 203-212

Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy

(20)  Pakker, Nadine G a   Kroon, Eugene D M B b   Roos, Marijke T L a   Otto, Sigrid A a   Hall, David c   Wit, Ferdinand W N M b   Hamann, Dörte a   Van der Ende, Marina E d   Claessen, Frans A P e   Kauffmann, Robert H f   Koopmans, Peter P g   Kroon, Frank P h   Ten Napel, Chris H H i   Sprenger, Herman G j   Weigel, Hugo M k   Montaner, Julio S G l   Lange, Joep M A b   Reiss, Peter b   Schellekens, Peter T A a,b   Miedema, Frank a,b,k  


Author keywords

Antiretroviral therapy; Long term immune reconstitution; Viral suppression

Indexed keywords

ANTIRETROVIRUS AGENT; CD27 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; DIDANOSINE; MONOCLONAL ANTIBODY; NEVIRAPINE; VIRUS RNA; ZIDOVUDINE;

EID: 0033010260     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199902040-00008     Document Type: Article
Times cited : (99)

References (37)
  • 1
    • 0030317628 scopus 로고
    • Survival in HIV-infected patients who have received zidovudine: Comparison of combination therapy with sequential monotherapy and continued zidovudine monotherapy
    • Graham NMH, Hoover DR, Park LP, et al.: Survival in HIV-infected patients who have received zidovudine: comparison of combination therapy with sequential monotherapy and continued zidovudine monotherapy. Ann Intern Med 1906, 124:1031-1038.
    • (1906) Ann Intern Med , vol.124 , pp. 1031-1038
    • Graham, N.M.H.1    Hoover, D.R.2    Park, L.P.3
  • 2
    • 0029896976 scopus 로고    scopus 로고
    • A controlled trial of nevirapine plus zidovudine versus zidovudine alone in p24 antigenaemic HIV-infected patients
    • Carr A, Vella S, De Jong MD, et al.: A controlled trial of nevirapine plus zidovudine versus zidovudine alone in p24 antigenaemic HIV-infected patients. AIDS 1996, 10:635-641.
    • (1996) AIDS , vol.10 , pp. 635-641
    • Carr, A.1    Vella, S.2    De Jong, M.D.3
  • 3
    • 10144244674 scopus 로고    scopus 로고
    • A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter
    • Hammer SM, Katzenstein DA, Hughes MD, et al.: A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. N Engl J Med 1996, 335:1081-1090.
    • (1996) N Engl J Med , vol.335 , pp. 1081-1090
    • Hammer, S.M.1    Katzenstein, D.A.2    Hughes, M.D.3
  • 4
    • 9444290697 scopus 로고    scopus 로고
    • Virologic and immunologic benefits of initial therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy
    • Schooley RT, Ramirez-Ronda C, Lange JMA, et al.: Virologic and immunologic benefits of initial therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy. J Infect Dis 1996, 173:1354-1366.
    • (1996) J Infect Dis , vol.173 , pp. 1354-1366
    • Schooley, R.T.1    Ramirez-Ronda, C.2    Lange, J.M.A.3
  • 5
    • 0030567824 scopus 로고    scopus 로고
    • Delta: A randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals
    • Delta Coordinating Committee: Delta: a randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals. Lancet 1996, 348:283-291.
    • (1996) Lancet , vol.348 , pp. 283-291
  • 6
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • Autran B, Carcelain C, Li TS, et al.: Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997, 277:112-116.
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, C.2    Li, T.S.3
  • 7
    • 13144306121 scopus 로고    scopus 로고
    • Patterns of T cell repopulation, viral load reduction and restoration of T cell function in human immunodefiency virus infected persons during therapy with different antiretrovirals
    • Pakker NG, Roos MTL, Van Leeuwen R, et al.: Patterns of T cell repopulation, viral load reduction and restoration of T cell function in human immunodefiency virus infected persons during therapy with different antiretrovirals. J AIDS Hum Retrovirol 1997, 16:318-326.
    • (1997) J AIDS Hum Retrovirol , vol.16 , pp. 318-326
    • Pakker, N.G.1    Roos, M.T.L.2    Van Leeuwen, R.3
  • 8
    • 0027225949 scopus 로고
    • Viral phenotype and T-cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine
    • Koot M, Schellekens PTA, Mulder JW, et al.: Viral phenotype and T-cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine. J Infect Dis 1993, 168:733-736.
    • (1993) J Infect Dis , vol.168 , pp. 733-736
    • Koot, M.1    Schellekens, P.T.A.2    Mulder, J.W.3
  • 9
    • 0029003494 scopus 로고
    • The predictive value of T cell function in vitro and pre AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam
    • Bindels PJE, Krol A, Roos MTL, et al.: The predictive value of T cell function in vitro and pre AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam. J Infect Dis 1995, 172:97-104.
    • (1995) J Infect Dis , vol.172 , pp. 97-104
    • Bindels, P.J.E.1    Krol, A.2    Roos, M.T.L.3
  • 10
    • 0032490305 scopus 로고    scopus 로고
    • Autran B: Lung-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease
    • Li TS, Tubiana R, Katlama C, Calvez V, Ait Mohand H, Autran B: Lung-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease. Lancet 1998, 351:1682-1686.
    • (1998) Lancet , vol.351 , pp. 1682-1686
    • Li, T.S.1    Tubiana, R.2    Katlama, C.3    Calvez, V.4    Ait Mohand, H.5
  • 11
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation
    • Pakker NG, Notermans DW, De Boer RJ, et al.: Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation. Nature Med 1998, 4:208-214.
    • (1998) Nature Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    De Boer, R.J.3
  • 12
    • 0032565098 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients
    • Monlaner JSG, Reiss P, Cooper DA, et al.: A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients. The INCAS trial. JAMA 1998, 279:930-937.
    • (1998) The INCAS Trial. JAMA , vol.279 , pp. 930-937
    • Monlaner, J.S.G.1    Reiss, P.2    Cooper, D.A.3
  • 13
    • 0030317268 scopus 로고    scopus 로고
    • Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV infection
    • D'Aquila RT, Hughes MD, Johnson VA, et al.: Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV infection. Ann Intern Med 1996, 124:1019-1030.
    • (1996) Ann Intern Med , vol.124 , pp. 1019-1030
    • D'Aquila, R.T.1    Hughes, M.D.2    Johnson, V.A.3
  • 14
    • 16944364799 scopus 로고    scopus 로고
    • High-dose nevirapine in previously untreated human immunodeficiency virus type 1-infected persons docs not result in sustained suppression of viral replication
    • De Jong MD, Vella S, Carr A, et al.: High-dose nevirapine in previously untreated human immunodeficiency virus type 1-infected persons docs not result in sustained suppression of viral replication. J Infect Dis 1997, 175:966-970.
    • (1997) J Infect Dis , vol.175 , pp. 966-970
    • De Jong, M.D.1    Vella, S.2    Carr, A.3
  • 16
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type-1 selected during therapy
    • Richman DD, Havlir D, Corbeil J, et al.: Nevirapine resistance mutations of human immunodeficiency virus type-1 selected during therapy. J Virol 1994, 68:1660-1666.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.D.1    Havlir, D.2    Corbeil, J.3
  • 17
    • 0030691757 scopus 로고    scopus 로고
    • Phenotypic and functional separation of memory and effector human CD8pos T cells
    • Hamann D, Baars PA, Rep MHG, et al.: Phenotypic and functional separation of memory and effector human CD8pos T cells. J Exp Med 1997, 186:1407-1418.
    • (1997) J Exp Med , vol.186 , pp. 1407-1418
    • Hamann, D.1    Baars, P.A.2    Rep, M.H.G.3
  • 20
    • 0032190411 scopus 로고    scopus 로고
    • Low T-cell responses to CD3 plus CD28 monoclonal antibodies are predictive of development of AIDS
    • Roos MTL, Prins M, Koot M, et al.: Low T-cell responses to CD3 plus CD28 monoclonal antibodies are predictive of development of AIDS. AIDS 1998, 12:1745-1751.
    • (1998) AIDS , vol.12 , pp. 1745-1751
    • Roos, M.T.L.1    Prins, M.2    Koot, M.3
  • 21
    • 0028069547 scopus 로고
    • A Rapid and simple PCR assay for quantification of human immunodeficiency virus type-1 RNA in plasma; Application to acute retroviral infection
    • Mulder, McKinney N, Christopherson C, Sninsky J, Greenfield L, Kwok S: A rapid and simple PCR assay for quantification of human immunodeficiency virus type-1 RNA in plasma; application to acute retroviral infection. J Clin Microbiol 1994, 32:292-300.
    • (1994) J Clin Microbiol , vol.32 , pp. 292-300
    • Mulder, J.1    McKinney, N.2    Christopherson, C.3    Sninsky, J.4    Greenfield, L.5    Kwok, S.6
  • 22
    • 0030949848 scopus 로고    scopus 로고
    • A rapid and simple method for extracting human immunodeficiency virus type 1 RNA from plasma: Enhanced sensitivity
    • Mulder J, Resnick R, Saget B, et al.: A rapid and simple method for extracting human immunodeficiency virus type 1 RNA from plasma: enhanced sensitivity. J Clin Microbiol 1997, 35:1278-1280.
    • (1997) J Clin Microbiol , vol.35 , pp. 1278-1280
    • Mulder, J.1    Resnick, R.2    Saget, B.3
  • 23
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986, 307-310.
    • (1986) Lancet , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 24
    • 0028812436 scopus 로고
    • Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy
    • Mackall CL, Fleisher TA, Brown M, et al.: Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy. N Engl J Med 1995, 332:143-149.
    • (1995) N Engl J Med , vol.332 , pp. 143-149
    • Mackall, C.L.1    Fleisher, T.A.2    Brown, M.3
  • 25
    • 0030833497 scopus 로고    scopus 로고
    • Constraints on CD4 recovery postchemotherapy in adults: Thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells
    • Hakim FT, Cepeda R, Kaimei S, et al.: Constraints on CD4 recovery postchemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells. Blood 1997, 90:3789-3798.
    • (1997) Blood , vol.90 , pp. 3789-3798
    • Hakim, F.T.1    Cepeda, R.2    Kaimei, S.3
  • 26
    • 0028943992 scopus 로고
    • In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
    • Condra JH, Schleif WA, Blahy OM, et al.: In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 1995, 374:569-571.
    • (1995) Nature , vol.374 , pp. 569-571
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 27
    • 0032568248 scopus 로고    scopus 로고
    • Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: Therapy and practice
    • Roberts NA, Craig JC, Sheldon J: Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: therapy and practice. AIDS 1998, 12:453-460.
    • (1998) AIDS , vol.12 , pp. 453-460
    • Roberts, N.A.1    Craig, J.C.2    Sheldon, J.3
  • 28
    • 0032493043 scopus 로고    scopus 로고
    • A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    • Carr A, Samaras K, Burton S, et al.: A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998, 12:F51-F58.
    • (1998) AIDS , vol.12
    • Carr, A.1    Samaras, K.2    Burton, S.3
  • 29
    • 0032551258 scopus 로고    scopus 로고
    • Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insuline resistance
    • Carr A, Samaras K, Chrisholm DJ, Cooper D: Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insuline resistance. Lancet 1998, 351:1881-1883.
    • (1998) Lancet , vol.351 , pp. 1881-1883
    • Carr, A.1    Samaras, K.2    Chrisholm, D.J.3    Cooper, D.4
  • 30
    • 15144339718 scopus 로고    scopus 로고
    • Alternative multidrug regimen provides improved suppression of HIV-1 reputation over triple therapy
    • Weverling GJ, Lange JMA, Jurriaans S, et al.: Alternative multidrug regimen provides improved suppression of HIV-1 reputation over triple therapy. AIDS 1998, 12:F117-F122.
    • (1998) AIDS , vol.12
    • Weverling, G.J.1    Lange, J.M.A.2    Jurriaans, S.3
  • 31
    • 19244367532 scopus 로고    scopus 로고
    • Maintenance therapy after quadruple induction therapy in HIV-1 infected individuals: Amsterdam Duration of Antiretroviral Medication (ADAM) study
    • Reijers MHE, Weverling GJ, Jurriaans S, et al.: Maintenance therapy after quadruple induction therapy in HIV-1 infected individuals: Amsterdam Duration of Antiretroviral Medication (ADAM) study. Lancet 1998, 352:185-190.
    • (1998) Lancet , vol.352 , pp. 185-190
    • Reijers, M.H.E.1    Weverling, G.J.2    Jurriaans, S.3
  • 32
    • 0030052964 scopus 로고    scopus 로고
    • Alterations in the immune response of human immunodeficiency virus (HIV) infected subjects treated with an HIV-specific protease inhibitor, ritonavir
    • Kelleher AD, Carr A, Zaunders J, Cooper DA: Alterations in the immune response of human immunodeficiency virus (HIV) infected subjects treated with an HIV-specific protease inhibitor, ritonavir. J Infect Dis 1996, 173:321-329.
    • (1996) J Infect Dis , vol.173 , pp. 321-329
    • Kelleher, A.D.1    Carr, A.2    Zaunders, J.3    Cooper, D.A.4
  • 33
    • 0032104145 scopus 로고    scopus 로고
    • High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection
    • McCune JM, Loftus R, Schmidt DK, et al.: High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection. J Clin Invest 1998, 101:2301-2308.
    • (1998) J Clin Invest , vol.101 , pp. 2301-2308
    • McCune, J.M.1    Loftus, R.2    Schmidt, D.K.3
  • 34
    • 0032548547 scopus 로고    scopus 로고
    • Failure isn't what it used to be ... but neither is success
    • Cohen J: Failure isn't what it used to be ... but neither is success. Science 1998, 279:1133-1134.
    • (1998) Science , vol.279 , pp. 1133-1134
    • Cohen, J.1
  • 35
    • 0032492398 scopus 로고    scopus 로고
    • CD4-count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART)
    • Kaufmann D, Pantaleo G, Sudre P, Telenti A: CD4-count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART). Lancet 1998, 351:723-724.
    • (1998) Lancet , vol.351 , pp. 723-724
    • Kaufmann, D.1    Pantaleo, G.2    Sudre, P.3    Telenti, A.4
  • 36
    • 0032499143 scopus 로고    scopus 로고
    • Improvement in CD4+ cell counts despite persistently detectable HIV load
    • Levitz SM: Improvement in CD4+ cell counts despite persistently detectable HIV load. New Engl J Med 1998, 338:1074-1075.
    • (1998) New Engl J Med , vol.338 , pp. 1074-1075
    • Levitz, S.M.1
  • 37
    • 0031907427 scopus 로고    scopus 로고
    • Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy
    • Gorochov G, Neumann AU, Kereveur A, et al.: Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nature Med 1998, 4:215-221.
    • (1998) Nature Med , vol.4 , pp. 215-221
    • Gorochov, G.1    Neumann, A.U.2    Kereveur, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.