Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

Blood

Volumn 99, Issue 12, 2002, Pages 4601-4609

  Taylor, Patricia A ^a,b,c   Friedman, Thea M ^a,b,c   Korngold, Robert ^a,b,c   Noelle, Randolph J ^a,b,c   Blazar, Bruce R ^a,b,c,d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; T LYMPHOCYTE RECEPTOR;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNITY; BONE MARROW TRANSPLANTATION; CELL ACTIVATION; CELL CONTACT; CONTROLLED STUDY; GRAFT VERSUS HOST REACTION; IMMUNOCOMPETENT CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0037097593     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.12.4601     Document Type: Article

References (20)

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8. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonat expansion of alloreactive human and mouse helper T lymphocytes
9. Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody
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12. "Infectious" transplantation tolerance
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14. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
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20. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta