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Volumn , Issue , 2011, Pages 65-118

Restoration of immunocompetence in aging and other inflammatory disease states by dehydroepiandrosterone- 3β-sulfate, an activator of the peroxisome proliferator-activated receptor alpha (PPARα)

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EID: 85064941368     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (4)

References (415)
  • 2
    • 0027200034 scopus 로고
    • Peroxisomal diseases
    • H. Harris, and K. Hirschhorn, editors. New York:Plenum Press
    • Moser, H.W. 1993. Peroxisomal diseases. In Advances in Human Genetics. H. Harris, and K. Hirschhorn, editors. New York:Plenum Press. 1-106
    • (1993) In Advances in Human Genetics , pp. 1-106
    • Moser, H.W.1
  • 4
  • 5
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann, I., and Green, S. 1990. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature. 347:645-650
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 6
    • 0029731662 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology
    • Lemberger, T., Desvergne, B., and Wahli, W. 1996. Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Ann. Rev. Cell. Dev. Biol. 12:335-363
    • (1996) Ann. Rev. Cell. Dev. Biol , vol.12 , pp. 335-363
    • Lemberger, T.1    Desvergne, B.2    Wahli, W.3
  • 7
    • 0022327612 scopus 로고
    • Steroid receptor regulated transcription of specific genes and gene networks
    • Yamamoto, K.R. 1985. Steroid receptor regulated transcription of specific genes and gene networks. Annu. Rev. Genet. 19:209-252
    • (1985) Annu. Rev. Genet , vol.19 , pp. 209-252
    • Yamamoto, K.R.1
  • 10
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
    • Green, S., Walter, V., Kumar, V., Krust, A., Bornet, J.-M., Argos, P., and Chambon, P. 1986. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 320:134-139
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, V.2    Kumar, V.3    Krust, A.4    Bornet, J.-M.5    Argos, P.6    Chambon, P.7
  • 11
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., and Chambon, P. 1990. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J. 9:1603-1614
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 12
    • 0026595896 scopus 로고
    • Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation Specificity for steroids and antihormones
    • Kemppainen, J.A., Lane, M.V., Sar, M., and Wilson, E.M. 1992. Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones. J. Biol. Chem. 267:968-974
    • (1992) J. Biol. Chem , vol.267 , pp. 968-974
    • Kemppainen, J.A.1    Lane, M.V.2    Sar, M.3    Wilson, E.M.4
  • 14
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N.J., Krust, A., and Chambon, P. 1987. A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature. 330:444-450
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 15
    • 0026557977 scopus 로고
    • Evolution of the nuclear receptor gene superfamily
    • Laudet, V., Hanni, C., Coll, J., Catzeflis, F., and Stehelin, D. 1992. Evolution of the nuclear receptor gene superfamily. EMBO J. 11:1003-1013
    • (1992) EMBO J , vol.11 , pp. 1003-1013
    • Laudet, V.1    Hanni, C.2    Coll, J.3    Catzeflis, F.4    Stehelin, D.5
  • 16
    • 0000101746 scopus 로고
    • PPAR: a key nuclear factor in nutrient/gene interactions?
    • P. Baeuerle, editor. Boston:Birkhauser
    • Desvergne, B., and Wahli, W. 1995. PPAR: a key nuclear factor in nutrient/gene interactions? In Inducible Transcriptions. P. Baeuerle, editor. Boston:Birkhauser. 142-176
    • (1995) In Inducible Transcriptions , pp. 142-176
    • Desvergne, B.1    Wahli, W.2
  • 18
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor retinoid X receptor heterodimers
    • Keller, H., Dreyer, C., Medin, J., Mahfoudi, A., Ozato, K., and Wahli, W. 1993. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor retinoid X receptor heterodimers. Proc. Natl. Acad. Sei. USA. 90:2160-2164
    • (1993) Proc. Natl. Acad. Sei. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 20
    • 0029916657 scopus 로고    scopus 로고
    • Hepatic peroxisome proliferation in vitamin A-deficient mice without a simultaneous increase in peroxisomal acyl-CoA oxidase activity
    • Solhenius, A.K., Reinfeldt, M., Backstrom, K., Bergstrand, A., and DePierre, J.W. 1996. Hepatic peroxisome proliferation in vitamin A-deficient mice without a simultaneous increase in peroxisomal acyl-CoA oxidase activity. Biochem. Pharmacol. 51:821-827
    • (1996) Biochem. Pharmacol , vol.51 , pp. 821-827
    • Solhenius, A.K.1    Reinfeldt, M.2    Backstrom, K.3    Bergstrand, A.4    DePierre, J.W.5
  • 21
    • 0028807753 scopus 로고
    • Peroxisome proliferation and associated effects caused by petrofluorooctanoic acid in vitamin A-deficient mice
    • Solhenius, A.K., Andersson, K., Olsson, J., and DePierre, J.W. 1995. Peroxisome proliferation and associated effects caused by petrofluorooctanoic acid in vitamin A-deficient mice. Chem. Biol. Interact. 98:45-50
    • (1995) Chem. Biol. Interact , vol.98 , pp. 45-50
    • Solhenius, A.K.1    Andersson, K.2    Olsson, J.3    DePierre, J.W.4
  • 22
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimerization of their receptors
    • Kliewer, S.A., Umesono, K., Noonan, D.J., Heyman, R.A., and Evans, R.M. 1992. Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimerization of their receptors. Nature. 358:771-774
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 23
    • 0027314960 scopus 로고
    • The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor
    • Isseman, I., Prince, R.A., Tugwood, J.D., and Green, S. 1993. The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor. Biochimie (Paris). 75:251-256
    • (1993) Biochimie (Paris) , vol.75 , pp. 251-256
    • Isseman, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 24
    • 0030771852 scopus 로고    scopus 로고
    • DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements
    • Juge-Aubry, C., Pernin, A., Favez, T., Burger, A.G., Wahli, W., Meier, C.A., and Desvergne, B. 1997. DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. J. Biol. Chem. 272:25252-25259
    • (1997) J. Biol. Chem , vol.272 , pp. 25252-25259
    • Juge-Aubry, C.1    Pernin, A.2    Favez, T.3    Burger, A.G.4    Wahli, W.5    Meier, C.A.6    Desvergne, B.7
  • 25
    • 0028332036 scopus 로고
    • Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers
    • Glass, C.K. 1994. Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocr. Rev. 15:391-407
    • (1994) Endocr. Rev , vol.15 , pp. 391-407
    • Glass, C.K.1
  • 26
    • 85064905441 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl-CoA oxidase gene
    • Tugwood, J.D., Issemann, I., Anderson, R.G., Bundeil, K.R., McPheat, W.L., and Green, S. 1992. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl-CoA oxidase gene. EMBO J
    • (1992) EMBO J
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundeil, K.R.4    McPheat, W.L.5    Green, S.6
  • 27
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G., and Wahli, W. 1992. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell. 68:879-887
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 28
    • 0029066447 scopus 로고
    • Novel sequence determinants in peroxisome proliferator signaling
    • Palmer, C.N., Hsu, M.H., Griffin, H.J., and Johnson, E.F. 1995. Novel sequence determinants in peroxisome proliferator signaling. J. Biol. Chem. 270:16114-16121
    • (1995) J. Biol. Chem , vol.270 , pp. 16114-16121
    • Palmer, C.N.1    Hsu, M.H.2    Griffin, H.J.3    Johnson, E.F.4
  • 29
    • 0031030718 scopus 로고    scopus 로고
    • Ligand-induced peroxisome proliferator-activated receptor alpha conformational change
    • Dowell, P., Peterson, V.J., Zabriskie, T.M., and Leid, M. 1997. Ligand-induced peroxisome proliferator-activated receptor alpha conformational change. J. Biol. Chem. 272:2013-2020
    • (1997) J. Biol. Chem , vol.272 , pp. 2013-2020
    • Dowell, P.1    Peterson, V.J.2    Zabriskie, T.M.3    Leid, M.4
  • 30
    • 0031439111 scopus 로고    scopus 로고
    • p300 functions as a coactivator for the peroxisome proliferator-activated receptor a
    • Dowell, I., J.E., Avram, D., Peterson, V.J., Nevrivy, D.J., and Leid, M. 1997. p300 functions as a coactivator for the peroxisome proliferator-activated receptor a. J. Biol. Chem. 272:33435-33443
    • (1997) J. Biol. Chem , vol.272 , pp. 33435-33443
    • Dowell, I.J.E.1    Avram, D.2    Peterson, V.J.3    Nevrivy, D.J.4    Leid, M.5
  • 31
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBPare histone acetyltransferases
    • Ogryzko, V.V., Schlitz, R.L., Russanova, V., Howard, B.H., and Nakatani, Y. 1996. The transcriptional coactivators p300 and CBPare histone acetyltransferases. Cell. 87:953-959
    • (1996) Cell , vol.87 , pp. 953-959
    • Ogryzko, V.V.1    Schlitz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 32
    • 0029665857 scopus 로고    scopus 로고
    • A p300/CBP-associated factor that competes with the adenoviral oncoprotein El A
    • Yang, X.J., Ogryzko, V.V., Nishikawa, J., Howard, B.H., and Nakatani, Y. 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein El A. Nature. 382:319-342
    • (1996) Nature , vol.382 , pp. 319-342
    • Yang, X.J.1    Ogryzko, V.V.2    Nishikawa, J.3    Howard, B.H.4    Nakatani, Y.5
  • 33
    • 0030480969 scopus 로고    scopus 로고
    • The CBP co-activator is a histone acetyltransferase
    • Bannister, A.J., and Kouzarides, T. 1996. The CBP co-activator is a histone acetyltransferase. Nature. 384:641-643
    • (1996) Nature , vol.384 , pp. 641-643
    • Bannister, A.J.1    Kouzarides, T.2
  • 34
    • 0030341454 scopus 로고    scopus 로고
    • Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma
    • Zhu, Y., Qi, C., Calandra, C., Rao, M.S., and Reddy, J.K. 1996. Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma. Gene Exp. 6:185-195
    • (1996) Gene Exp , vol.6 , pp. 185-195
    • Zhu, Y.1    Qi, C.2    Calandra, C.3    Rao, M.S.4    Reddy, J.K.5
  • 35
    • 1842295133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors
    • DiRenzo, J., Soderstrom, M., Kurokawa, R., Ogliastro, M.H., Ricote, M., Ingrey, S., Horlein, A., Rosenfeld, M.G., and Glass, C.K. 1997. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol. Cell. Biol. 17:2166-2176
    • (1997) Mol. Cell. Biol , vol.17 , pp. 2166-2176
    • DiRenzo, J.1    Soderstrom, M.2    Kurokawa, R.3    Ogliastro, M.H.4    Ricote, M.5    Ingrey, S.6    Horlein, A.7    Rosenfeld, M.G.8    Glass, C.K.9
  • 36
    • 0030570961 scopus 로고    scopus 로고
    • A growing coactivator network
    • Janknecht, R., and Hunter, T. 1996. A growing coactivator network. Nature. 383:22-23
    • (1996) Nature , vol.383 , pp. 22-23
    • Janknecht, R.1    Hunter, T.2
  • 37
    • 0027504874 scopus 로고
    • Identification of two mPPAR related receptors and evidence for the existence of five subfamily members
    • Chen, F., Law, S.W., and O'Malley, B.W. 1993. Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochem. Biophys. Res. Comm. 196:671-677
    • (1993) Biochem. Biophys. Res. Comm , vol.196 , pp. 671-677
    • Chen, F.1    Law, S.W.2    O'Malley, B.W.3
  • 38
    • 0026785388 scopus 로고
    • Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
    • Schmidt, A., Endo, N., Rutledge, S.J., Vogel, R., Shinar, D., and Rodan, G.A. 1992. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol. Endocrin. 6:1634-1641
    • (1992) Mol. Endocrin , vol.6 , pp. 1634-1641
    • Schmidt, A.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Shinar, D.5    Rodan, G.A.6
  • 39
    • 0027191040 scopus 로고
    • cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator-activated receptor
    • Sher, T., Yi, H.F., McBride, O.W., and Gonzalez, F.J. 1993. cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator-activated receptor. Biochem. 32:5598-5604
    • (1993) Biochem , vol.32 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    McBride, O.W.3    Gonzalez, F.J.4
  • 40
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator-activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping
    • Greene, M.E., Blumberg, B., McBride, O.W., Yi, H.F., Kronquist, K., Kwan, K., Hsieh, L., Greene, G., and Nimer, S.D. 1995. Isolation of the human peroxisome proliferator-activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Exp. 4:281-299
    • (1995) Gene Exp , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3    Yi, H.F.4    Kronquist, K.5    Kwan, K.6    Hsieh, L.7    Greene, G.8    Nimer, S.D.9
  • 41
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
    • Zhu, Y., Alvares, K., Huang, Q., Rao, M.S., and Reddy, J.K. 1993. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J. Biol. Chem. 268:26817-26820
    • (1993) J. Biol. Chem , vol.268 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5
  • 43
    • 0028909362 scopus 로고
    • Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes
    • Amri, E.Z., Bonino, F., Ailhaud, G., Abumrad, N.A., and Grimaldi, P.A. 1995. Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. J. Biol. Chem. 270:2367-2371
    • (1995) J. Biol. Chem , vol.270 , pp. 2367-2371
    • Amri, E.Z.1    Bonino, F.2    Ailhaud, G.3    Abumrad, N.A.4    Grimaldi, P.A.5
  • 45
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the Clofibrate acid-activated receptor and the glucocorticoid receptor
    • Göttlicher, M., Widmark, E., Li, Q., and Gustafsson, J.-A. 1992. Fatty acids activate a chimera of the Clofibrate acid-activated receptor and the glucocorticoid receptor. Biochem. 89:4653-4657
    • (1992) Biochem , vol.89 , pp. 4653-4657
    • Göttlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.-A.4
  • 46
    • 0029121281 scopus 로고
    • cDNA cloning and characterization of the transcriptional activities of the hamster peroxisome proliferator-activated receptor haPPARgamma
    • Aperlo, C., Pognonec, P., Saladin, R., Auwerx, J., and Boulukos, K.E. 1995. cDNA cloning and characterization of the transcriptional activities of the hamster peroxisome proliferator-activated receptor haPPARgamma. Gene. 162:297-302
    • (1995) Gene , vol.162 , pp. 297-302
    • Aperlo, C.1    Pognonec, P.2    Saladin, R.3    Auwerx, J.4    Boulukos, K.E.5
  • 47
    • 0031590465 scopus 로고    scopus 로고
    • Characterisation of bovine peroxisome proliferator-activated receptors γ and γ2: genetic mapping and differential expression of the two isoforms
    • Sundvold, H., Brzozowska, A., and Lien, S. 1997. Characterisation of bovine peroxisome proliferator-activated receptors γ and γ2: genetic mapping and differential expression of the two isoforms. Biochem. Biophys. Res. Comm. 239:857-861
    • (1997) Biochem. Biophys. Res. Comm , vol.239 , pp. 857-861
    • Sundvold, H.1    Brzozowska, A.2    Lien, S.3
  • 48
    • 0031577669 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptors in Atlantic salmon (Salmo salar): effects on PPAR transcription and acyl-CoA oxidase activity in hepatocytes by peroxisome proliferators and fatty acids
    • Ruyter, B., Andersen, O., Dehli, A., Farrants, A.-K.O., Gjoen, T., and Thomassen, M.S. 1997. Peroxisome proliferator activated receptors in Atlantic salmon (Salmo salar): effects on PPAR transcription and acyl-CoA oxidase activity in hepatocytes by peroxisome proliferators and fatty acids. Biochim. Biophys. Acta. 1348:331-338
    • (1997) Biochim. Biophys. Acta , vol.1348 , pp. 331-338
    • Ruyter, B.1    Andersen, O.2    Dehli, A.3    Farrants, A.-K.O.4    Gjoen, T.5    Thomassen, M.S.6
  • 49
    • 0030481595 scopus 로고    scopus 로고
    • Studies on the role of PPAR in the fibrate-modulated gene expression of apolipoprotein A-I, plasminogen activator inhibitor 1, and fibrinogen in primary hepatocyte cultures from cynomolgus monkey
    • Kockx, M., Princen, H.M., and Kooistra, T. 1996. Studies on the role of PPAR in the fibrate-modulated gene expression of apolipoprotein A-I, plasminogen activator inhibitor 1, and fibrinogen in primary hepatocyte cultures from cynomolgus monkey. Ann. N.Y.Acad. Sei. 804:711-712
    • (1996) Ann. N.Y.Acad. Sei , vol.804 , pp. 711-712
    • Kockx, M.1    Princen, H.M.2    Kooistra, T.3
  • 50
    • 0031408955 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans
    • Guan, Y., Zhang, Y., Davis, L., and Breyer, M.D. 1997. Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. Am. J. Physiol. 273:F1013-1022
    • (1997) Am. J. Physiol , vol.273 , pp. F1013-F1022
    • Guan, Y.1    Zhang, Y.2    Davis, L.3    Breyer, M.D.4
  • 51
    • 0027290892 scopus 로고
    • Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome-proliferator-mediated signaling
    • Miyata, K.S., Zhang, B., Marcus, S.L., Capone, J.P., and Rachubinski, R.A. 1993. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome-proliferator-mediated signaling. J. Biol. Chem. 268:19169-19172
    • (1993) J. Biol. Chem , vol.268 , pp. 19169-19172
    • Miyata, K.S.1    Zhang, B.2    Marcus, S.L.3    Capone, J.P.4    Rachubinski, R.A.5
  • 52
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α,-β, and-γ in the adult rat
    • Braissant, O., Foufelle, F., Scotto, C., Dauca, M., and Wahli, W. 1996. Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α,-β, and-γ in the adult rat. Endocrinol. 137:354-366
    • (1996) Endocrinol , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 53
    • 85064908153 scopus 로고    scopus 로고
    • PPARa activation modulates cellular redox status, represses NFkB signaling, and reduces inflammatory cytokine production in aging
    • accepted
    • Poynter, M.E., and Daynes, R.A. accepted. PPARa activation modulates cellular redox status, represses NFkB signaling, and reduces inflammatory cytokine production in aging. J. Biol. Chem
    • J. Biol. Chem
    • Poynter, M.E.1    Daynes, R.A.2
  • 54
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-a in humans
    • Auboeuf, D., Rieusset, J., Fajas, L., Vallier, P., Frering, V., Riou, J.P., Staels, B., Auwerx, J., Laville, M., and Vidal, H. 1997. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-a in humans. Diabetes. 46:1319-1327
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3    Vallier, P.4    Frering, V.5    Riou, J.P.6    Staels, B.7    Auwerx, J.8    Laville, M.9    Vidal, H.10
  • 56
    • 0024509605 scopus 로고
    • Biochemical mechanisms of induction of hepatic peroxisome proliferation
    • Lock, E.A., Mitchell, A.M., and Elcombe, C.R. 1989. Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu. Rev. Pharmacol. Toxicol. 29:145-163
    • (1989) Annu. Rev. Pharmacol. Toxicol , vol.29 , pp. 145-163
    • Lock, E.A.1    Mitchell, A.M.2    Elcombe, C.R.3
  • 57
    • 0022924249 scopus 로고
    • Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms
    • Elcombe, C.R., and Mitchell, A.M. 1986. Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms. Environ. Health Perspect. 70:211-219
    • (1986) Environ. Health Perspect , vol.70 , pp. 211-219
    • Elcombe, C.R.1    Mitchell, A.M.2
  • 59
    • 0025598930 scopus 로고
    • Toxicological studies on a benzofuran derivative III. Comparison of peroxisome proliferation in rat and human hepatocytes in primary culture
    • Bichet, N., Cahard, D., Fabre, G., Remandet, B., Gouy, D., and Cano, J.-P. 1990. Toxicological studies on a benzofuran derivative. III. Comparison of peroxisome proliferation in rat and human hepatocytes in primary culture. Toxicol. Appl. Pharmacol. 106:509-517
    • (1990) Toxicol. Appl. Pharmacol , vol.106 , pp. 509-517
    • Bichet, N.1    Cahard, D.2    Fabre, G.3    Remandet, B.4    Gouy, D.5    Cano, J.-P.6
  • 60
    • 0024410242 scopus 로고
    • Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset
    • Lake, B.G., Evans, J.G., Gray, T.J., Korosi, S.A., and North, C.J. 1989. Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset. Toxicol. Appl. Pharmacol. 99:148-160
    • (1989) Toxicol. Appl. Pharmacol , vol.99 , pp. 148-160
    • Lake, B.G.1    Evans, J.G.2    Gray, T.J.3    Korosi, S.A.4    North, C.J.5
  • 63
    • 0032526060 scopus 로고    scopus 로고
    • Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPARa is functional and mediates peroxisome proliferator-induced hypolipidaemia
    • Bell, A.R., Savory, R., Horley, N.J., Choudhury, A.I., Dickins, M., Gray, T.J.B., Salter, A.M., and Bell, D.R. 1998. Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPARa is functional and mediates peroxisome proliferator-induced hypolipidaemia. Biochem. J. 332:689-693
    • (1998) Biochem. J , vol.332 , pp. 689-693
    • Bell, A.R.1    Savory, R.2    Horley, N.J.3    Choudhury, A.I.4    Dickins, M.5    Gray, T.J.B.6    Salter, A.M.7    Bell, D.R.8
  • 64
    • 0345437254 scopus 로고    scopus 로고
    • Orphan nuclear receptors and their ligands
    • L. P. Freedman, editor. Boston:Birkhauser
    • Forman, B.M. 1997. Orphan nuclear receptors and their ligands. In Biology of Steroid and Nuclear Hormone Receptors. L. P. Freedman, editor. Boston:Birkhauser. 281-305
    • (1997) In Biology of Steroid and Nuclear Hormone Receptors , pp. 281-305
    • Forman, B.M.1
  • 65
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARy)
    • Lehmann, J.M., Moore, L.B., Smith-Oliver, T.A., Wilkison, W.O., Willson, T.M., and Kliewer, S.A. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARy). J. Biol. Chem. 270:12953-12956
    • (1995) J. Biol. Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 66
    • 0032052816 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signaling
    • Desvergne, B., Ijpenberg, A., Devchand, P.R., and Wahli, W. 1998. The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signaling. J. Steroid Biochem. Mol. Biol. 65:65-74
    • (1998) J. Steroid Biochem. Mol. Biol , vol.65 , pp. 65-74
    • Desvergne, B.1    Ijpenberg, A.2    Devchand, P.R.3    Wahli, W.4
  • 67
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome peroliferator-activated receptor γ and promotes adipocyte differentiation
    • Kliewer, S.A., Lenhard, J.M., Wilson, T.W., Patel, I., Morris, D.C., and Lehmann, J.A. 1995. A prostaglandin J2 metabolite binds peroxisome peroliferator-activated receptor γ and promotes adipocyte differentiation. Cell. 83:813-819
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Wilson, T.W.3    Patel, I.4    Morris, D.C.5    Lehmann, J.A.6
  • 68
    • 0028972025 scopus 로고
    • 15-Deoxy-A1214-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARy
    • Forman, B.M., Tontonoz, P., Chen, J., Brun, R.P., Spiegelman, B.M., and Evans, R.M. 1995. 15-Deoxy-A1214-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARy. Cell. 83:803-812
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 69
    • 0030035696 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor a inhibits hepatic S14 gene transcription: Evidence against the peroxisome proliferator-activated receptor a as the mediator of polyunsaturated fatty acid regulation ofS14 gene transcription
    • Ren, B., Thelen, A., and Jump, D.B. 1996. Peroxisome proliferator-activated receptor a inhibits hepatic S14 gene transcription: Evidence against the peroxisome proliferator-activated receptor a as the mediator of polyunsaturated fatty acid regulation ofS14 gene transcription. J. Biol. Chem. 271:17167-17173
    • (1996) J. Biol. Chem , vol.271 , pp. 17167-17173
    • Ren, B.1    Thelen, A.2    Jump, D.B.3
  • 70
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
    • Schoonjans, K., Staels, B., and Auwerx, J. 1996. Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37:907-925
    • (1996) J. Lipid Res , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 74
    • 0032104046 scopus 로고    scopus 로고
    • Fat chance of immunomodulation
    • Calder, P.C. 1998. Fat chance of immunomodulation. Immunol. Today. 19:277-247
    • (1998) Immunol. Today , vol.19 , pp. 247-277
    • Calder, P.C.1
  • 75
    • 0032055512 scopus 로고    scopus 로고
    • Effect of dietary treatment of rats with eicosapentaenoic acid or docosahexaenoic acid on hepatic lipid metabolism
    • Osmundsen, H., Braud, H., Beauseigneur, F., Gresti, J., Tsoko, M., and Clouet, P. 1998. Effect of dietary treatment of rats with eicosapentaenoic acid or docosahexaenoic acid on hepatic lipid metabolism. Biochem. 7.331:153-160
    • (1998) Biochem , vol.7 , Issue.331 , pp. 153-160
    • Osmundsen, H.1    Braud, H.2    Beauseigneur, F.3    Gresti, J.4    Tsoko, M.5    Clouet, P.6
  • 76
    • 0027739631 scopus 로고
    • Dietary manipulation by perilla oil and fish oil of hepatic lipids and its influence on peroxisomal β-oxidation and serum lipids in rat and mouse
    • Kawashima, Y., and Kozuka, H. 1993. Dietary manipulation by perilla oil and fish oil of hepatic lipids and its influence on peroxisomal β-oxidation and serum lipids in rat and mouse. Biol. Pharm. Bull. 16:1194-1199
    • (1993) Biol. Pharm. Bull , vol.16 , pp. 1194-1199
    • Kawashima, Y.1    Kozuka, H.2
  • 77
    • 0023722255 scopus 로고
    • On the mechanism of induction of the enzyme systems for peroxisomal β-oxidation of fatty acids by diets rich in partially hydrogenated fish oil
    • Fiatmark, T., Nilsson, A., Kvannes, J., Eikhom, T.S., Fukami, M.H., Kryvi, H., and Christiansen, E.N. 1988. On the mechanism of induction of the enzyme systems for peroxisomal β-oxidation of fatty acids by diets rich in partially hydrogenated fish oil. Biochim. Biophys. Acta. 962:122-130
    • (1988) Biochim. Biophys. Acta , vol.962 , pp. 122-130
    • Fiatmark, T.1    Nilsson, A.2    Kvannes, J.3    Eikhom, T.S.4    Fukami, M.H.5    Kryvi, H.6    Christiansen, E.N.7
  • 78
    • 0028289751 scopus 로고
    • Peroxisomes in liver, heart, and kidney of mice fed a commercial fish oil preparation: original data and review on peroxisomal changes induced by high-fat diets 7
    • De Craemer, D., Vamecq, J., Roels, F., Vallee, L., Pauwels, M., and Van den Branden, C. 1994. Peroxisomes in liver, heart, and kidney of mice fed a commercial fish oil preparation: original data and review on peroxisomal changes induced by high-fat diets. 7. Lipid Res. 35:1241-1250
    • (1994) Lipid Res , vol.35 , pp. 1241-1250
    • De Craemer, D.1    Vamecq, J.2    Roels, F.3    Vallee, L.4    Pauwels, M.5    Van den Branden, C.6
  • 79
    • 0023110975 scopus 로고
    • Effect of a high-fat diet with partially hydrogenated fish oil on long chain fatty acid metabolizing enzymes in subcellular fractions of rat liver
    • Berge, R.K., Fiatmark, T., and Christiansen, E.N. 1987. Effect of a high-fat diet with partially hydrogenated fish oil on long chain fatty acid metabolizing enzymes in subcellular fractions of rat liver. Arch. Biochem. Biophys. 252:269-276
    • (1987) Arch. Biochem. Biophys , vol.252 , pp. 269-276
    • Berge, R.K.1    Fiatmark, T.2    Christiansen, E.N.3
  • 80
    • 0022547218 scopus 로고
    • Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet
    • Kryvi, H., Christiansen, E., Tangeras, A., and Fiatmark, T. 1986. Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. Biochim. Biophys. Acta. 881:87-92
    • (1986) Biochim. Biophys. Acta , vol.881 , pp. 87-92
    • Kryvi, H.1    Christiansen, E.2    Tangeras, A.3    Fiatmark, T.4
  • 81
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman, B.M., Chen, J., and Evans, R.M. 1997. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc. Natl. Acad. Sei. USA. 94:4312-4317
    • (1997) Proc. Natl. Acad. Sei. USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 82
    • 0029955823 scopus 로고    scopus 로고
    • Identification of fatty acid methyl ester as naturally occurring transcriptional regulators of the members of the peroxisome proliferator-activated receptor family
    • Schmidt, A., Vogel, R.L., Witherup, K.M., Rutledge, S.J., Pitzenberger, S.M., Adam, M., and Rodan, G.A. 1996. Identification of fatty acid methyl ester as naturally occurring transcriptional regulators of the members of the peroxisome proliferator-activated receptor family. Lipids. 31:1115-1124
    • (1996) Lipids , vol.31 , pp. 1115-1124
    • Schmidt, A.1    Vogel, R.L.2    Witherup, K.M.3    Rutledge, S.J.4    Pitzenberger, S.M.5    Adam, M.6    Rodan, G.A.7
  • 85
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors a and β are activated by indomethacin and other non-steroidal anti-inflammatory drugs 7
    • Lehmann, J.M., Lenhard, J.M., Oliver, B.B., Ringold, G.M., and Kliewer, S.A. 1997. Peroxisome proliferator-activated receptors a and β are activated by indomethacin and other non-steroidal anti-inflammatory drugs. 7. Biol. Chem. 272:3406-3410
    • (1997) Biol. Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 86
    • 0024375066 scopus 로고
    • Induction of peroxisomal beta-oxidation in the rat liver in vivo and in vitro by tetrazole-substituted acetophenones: structure activity relationships
    • Eacho, P.I., Foxworthy, P.S., Dillard, R.P., Whitesitt, C.A., Herron, D., K., and Marshall, W.S. 1989. Induction of peroxisomal beta-oxidation in the rat liver in vivo and in vitro by tetrazole-substituted acetophenones: structure activity relationships. Toxicol. Appl. Pharmacol. 100:177-184
    • (1989) Toxicol. Appl. Pharmacol , vol.100 , pp. 177-184
    • Eacho, P.I.1    Foxworthy, P.S.2    Dillard, R.P.3    Whitesitt, C.A.4    Herron, D.K.5    Marshall, W.S.6
  • 87
    • 43949166063 scopus 로고
    • Induction of peroxisomal β-oxidation by structural analogues of dehydroepiandrosterone in cultured rat hepatocytes: structure-activity relationships
    • Sakuma, M., Yamada, J., and Suga, T. 1993. Induction of peroxisomal β-oxidation by structural analogues of dehydroepiandrosterone in cultured rat hepatocytes: structure-activity relationships. Biochim. Biophys. Acta. 1169:66-72
    • (1993) Biochim. Biophys. Acta , vol.1169 , pp. 66-72
    • Sakuma, M.1    Yamada, J.2    Suga, T.3
  • 88
    • 0029557218 scopus 로고
    • Peroxisome proliferation: current mechanisms relating to non-genotoxic carcinogenesis
    • Lake, B.G. 1995. Peroxisome proliferation: current mechanisms relating to non-genotoxic carcinogenesis. Toxicol. Lett. 82/83:673-681
    • (1995) Toxicol. Lett , vol.82-83 , pp. 673-681
    • Lake, B.G.1
  • 90
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance, B., Sies, H., and Boveris, A. 1979. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:527-605
    • (1979) Physiol. Rev , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 91
    • 0027078768 scopus 로고
    • Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice
    • Demoz, A., Willumsen, N., and Berge, R.K. 1992. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice. Lipids. 27:968-971
    • (1992) Lipids , vol.27 , pp. 968-971
    • Demoz, A.1    Willumsen, N.2    Berge, R.K.3
  • 92
    • 0021679964 scopus 로고
    • Sequential alterations in the micro-localization of catalase in mouse liver after treatment with hypolipidemic drugs
    • Klucis, E., Crane, D., and Masters, C. 1985. Sequential alterations in the micro-localization of catalase in mouse liver after treatment with hypolipidemic drugs. Molec. Cell. Biochem. 65:73-82
    • (1985) Molec. Cell. Biochem , vol.65 , pp. 73-82
    • Klucis, E.1    Crane, D.2    Masters, C.3
  • 93
    • 0025091776 scopus 로고
    • Long-term effects of hypolipidemic peroxisome proliferator administration on hepatic hydrogen peroxide metabolism in rats
    • Tamura, H., Iida, T., Watanabe, T., and Suga, T. 1990. Long-term effects of hypolipidemic peroxisome proliferator administration on hepatic hydrogen peroxide metabolism in rats. Carcinogenesis. 11:445-450
    • (1990) Carcinogenesis , vol.11 , pp. 445-450
    • Tamura, H.1    Iida, T.2    Watanabe, T.3    Suga, T.4
  • 94
    • 0032489437 scopus 로고    scopus 로고
    • Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor a (PPARa)./
    • Aoyama, T., Peters, J.M., Iritani, N., Nakajima, T., Furihata, K., Hashimoto, T., and Gonzalez, F.J. 1998. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor a (PPARa)./. Biol. Chem. 273:5678-5684
    • (1998) Biol. Chem , vol.273 , pp. 5678-5684
    • Aoyama, T.1    Peters, J.M.2    Iritani, N.3    Nakajima, T.4    Furihata, K.5    Hashimoto, T.6    Gonzalez, F.J.7
  • 95
    • 0017648177 scopus 로고
    • Lymphocyte-mediated cytotoxicity: effects of ageing, adult thymectomy, and thymic factor
    • Bach, M.A. 1977. Lymphocyte-mediated cytotoxicity: effects of ageing, adult thymectomy, and thymic factor. J. Immunol. 119:641-647
    • (1977) J. Immunol , vol.119 , pp. 641-647
    • Bach, M.A.1
  • 96
    • 0032508696 scopus 로고    scopus 로고
    • Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor a
    • Brandt, J.M., Djouadi, F., and Kelly, D.P. 1998. Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor a. J. Biol. Chem. 273:23786-23792
    • (1998) J. Biol. Chem , vol.273 , pp. 23786-23792
    • Brandt, J.M.1    Djouadi, F.2    Kelly, D.P.3
  • 97
    • 0032502704 scopus 로고    scopus 로고
    • Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor
    • Mascaro, C., Acosta, E., Oritz, J., Marrero, P., Hegardt, F., and Haro, D. 1998. Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor. J. Biol. Chem. 273:8560-8563
    • (1998) J. Biol. Chem , vol.273 , pp. 8560-8563
    • Mascaro, C.1    Acosta, E.2    Oritz, J.3    Marrero, P.4    Hegardt, F.5    Haro, D.6
  • 99
    • 0027273699 scopus 로고
    • Plasma dehydroepiandrosterone sulfate serves as a prehormone for 48% of follicular fluid testosterone during treatment with menotropins
    • Haning Jr, R.V., Hackett, R.J., Flood, C.A., Loughlin, J.S., Zhao, Q.Y., and Longcope, C. 1993. Plasma dehydroepiandrosterone sulfate serves as a prehormone for 48% of follicular fluid testosterone during treatment with menotropins. J. Clin. Endocrinol. Metab. 76:1301-1307
    • (1993) J. Clin. Endocrinol. Metab , vol.76 , pp. 1301-1307
    • Haning, R.V.1    Hackett, R.J.2    Flood, C.A.3    Loughlin, J.S.4    Zhao, Q.Y.5    Longcope, C.6
  • 100
    • 0023741331 scopus 로고
    • The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging
    • Regelson, W., Loria, R., and Kalimi, M. 1988. The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging. Ann. N. Y Acad. Sei. 521:260-273
    • (1988) Ann. N. Y Acad. Sei , vol.521 , pp. 260-273
    • Regelson, W.1    Loria, R.2    Kalimi, M.3
  • 101
    • 0028309503 scopus 로고
    • Dehydroepiandrosterone (DHEA)-the multifucntional steroid II Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action?
    • Regelson, W., and Kalimi, M. 1994. Dehydroepiandrosterone (DHEA)-the multifucntional steroid II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action? Ann. N.Y.Acad. Sei. 719:564-575
    • (1994) Ann. N.Y.Acad. Sei , vol.719 , pp. 564-575
    • Regelson, W.1    Kalimi, M.2
  • 102
    • 0028309696 scopus 로고
    • Dehydroepiandrosterone (DHEA)-the "mother steroid" I Immunologic action
    • Regelson, W., Loria, R., and Kalimi, M. 1994. Dehydroepiandrosterone (DHEA)-the "mother steroid" I. Immunologic action. Ann. N.Y.Acad. Sei. 719:553-562
    • (1994) Ann. N.Y.Acad. Sei , vol.719 , pp. 553-562
    • Regelson, W.1    Loria, R.2    Kalimi, M.3
  • 103
    • 0025091447 scopus 로고
    • The neurosteroid DHEAS is an allosteric antagonist of the GAB A receptor
    • Majewska, M.D., Demirogen, S., Spivak, C.E., and London, E.D. 1990. The neurosteroid DHEAS is an allosteric antagonist of the GAB A receptor. Brain Research. 526:143-146
    • (1990) Brain Research , vol.526 , pp. 143-146
    • Majewska, M.D.1    Demirogen, S.2    Spivak, C.E.3    London, E.D.4
  • 104
    • 0027093096 scopus 로고
    • Phenotypic properties of liver tumors induced by dehydroepiandrosterone in F-344 rats
    • Rao, M.S., Subbarao, V., Kumar, S., Yeldandi, A.V., and Reddy, J.K. 1992. Phenotypic properties of liver tumors induced by dehydroepiandrosterone in F-344 rats. J.P.N. J. Cancer Res. 83:1179-1183
    • (1992) J.P.N. J. Cancer Res , vol.83 , pp. 1179-1183
    • Rao, M.S.1    Subbarao, V.2    Kumar, S.3    Yeldandi, A.V.4    Reddy, J.K.5
  • 105
    • 0026531580 scopus 로고
    • Dehydroepisterone-induced peroxisome proliferation in the rat liver
    • Rao, M.S., Musunuri, S., and Reddy, J.K. 1992. Dehydroepisterone-induced peroxisome proliferation in the rat liver. Pathobiology. 60:82-86
    • (1992) Pathobiology , vol.60 , pp. 82-86
    • Rao, M.S.1    Musunuri, S.2    Reddy, J.K.3
  • 106
    • 0027971913 scopus 로고
    • Dehydroepiandrosterone-induced peroxisome proliferation in the rat: Evaluation of sex differences
    • Rao, M.S., Reid, B., Ide, H., Subbaro, I.V., and Reddy, J.K. 1994. Dehydroepiandrosterone-induced peroxisome proliferation in the rat: Evaluation of sex differences. Proc. Soc. Exp. Biol. Med. 207:186-190
    • (1994) Proc. Soc. Exp. Biol. Med , vol.207 , pp. 186-190
    • Rao, M.S.1    Reid, B.2    Ide, H.3    Subbaro, I.V.4    Reddy, J.K.5
  • 107
    • 0030478960 scopus 로고    scopus 로고
    • Hepatocarcinogenesis of peroxisome proliferators
    • Rao, M.S., and Reddy, J.K. 1996. Hepatocarcinogenesis of peroxisome proliferators. Ann. N.Y. Acad. Sei. 804: 573-587
    • (1996) Ann. N.Y. Acad. Sei , vol.804 , pp. 573-587
    • Rao, M.S.1    Reddy, J.K.2
  • 108
    • 0025752416 scopus 로고
    • Characteristics of dehydroepiandrosterone as a peroxisome proliferator
    • Yamada, J., Sakuma, M., Ikeda, T., Fukuda, K., and Suga, T. 1991. Characteristics of dehydroepiandrosterone as a peroxisome proliferator. Biochim. Biophys. Acta. 1092:233-243
    • (1991) Biochim. Biophys. Acta , vol.1092 , pp. 233-243
    • Yamada, J.1    Sakuma, M.2    Ikeda, T.3    Fukuda, K.4    Suga, T.5
  • 109
    • 0026558149 scopus 로고
    • Comparison of the inducing effect of dehydroepiandrosterone on hepatic peroxisome proliferation-associated enzymes in several rodent species A short term administration study
    • Sakuma, M., Yamada, J., and Suga, T. 1992. Comparison of the inducing effect of dehydroepiandrosterone on hepatic peroxisome proliferation-associated enzymes in several rodent species. A short term administration study. Biochem. Pharmacol. 43:1269-1273
    • (1992) Biochem. Pharmacol , vol.43 , pp. 1269-1273
    • Sakuma, M.1    Yamada, J.2    Suga, T.3
  • 110
    • 0028046262 scopus 로고
    • Characteristics of the hepatocarcinogenesis caused by dehydroepiandrosterone, a peroxisome proliferator, in male F-344 rats
    • Hayashi, F., Tamura, H., Yamada, J., Kasai, H., and Suga, T. 1994. Characteristics of the hepatocarcinogenesis caused by dehydroepiandrosterone, a peroxisome proliferator, in male F-344 rats. Carcinogenesis. 15:2215-2219
    • (1994) Carcinogenesis , vol.15 , pp. 2215-2219
    • Hayashi, F.1    Tamura, H.2    Yamada, J.3    Kasai, H.4    Suga, T.5
  • 112
    • 0028308486 scopus 로고
    • Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolites in rats
    • Prough, R.A., Webb, S.J., Wu, H.-Q., Lapenson, D.P., and Waxman, D.J. 1994. Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolites in rats. Cancer Res. 54: 2878-2886
    • (1994) Cancer Res , vol.54 , pp. 2878-2886
    • Prough, R.A.1    Webb, S.J.2    Wu, H.-Q.3    Lapenson, D.P.4    Waxman, D.J.5
  • 113
    • 0023184464 scopus 로고
    • Characterization of ciprofibrate and clofibric acid as peroxisomal proliferators in primary cultures of rat hepatocytes
    • Feller, D.R., Singh, Y., Shirhatti, V.R., Kocarek, T.A., Liu, C.T., and Krishna, G. 1987. Characterization of ciprofibrate and clofibric acid as peroxisomal proliferators in primary cultures of rat hepatocytes. Hepatology. 7:508-516
    • (1987) Hepatology , vol.7 , pp. 508-516
    • Feller, D.R.1    Singh, Y.2    Shirhatti, V.R.3    Kocarek, T.A.4    Liu, C.T.5    Krishna, G.6
  • 114
    • 0023261752 scopus 로고
    • Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary rat hepatocytes
    • Kocarek, T.A., and Feller, D.R. 1987. Induction of peroxisomal fatty acyl-CoA oxidase and microsomal laurate hydroxylase activities by beclobric acid and two metabolites in primary rat hepatocytes. Biochem. Pharmacol. 36:3027-3032
    • (1987) Biochem. Pharmacol , vol.36 , pp. 3027-3032
    • Kocarek, T.A.1    Feller, D.R.2
  • 115
    • 0024326908 scopus 로고
    • Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes
    • Kocarek, T.A., and Feller, D.R. 1989. Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. Biochem. Pharmacol. 38:4169-4176
    • (1989) Biochem. Pharmacol , vol.38 , pp. 4169-4176
    • Kocarek, T.A.1    Feller, D.R.2
  • 117
    • 0025939158 scopus 로고
    • Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in primary rat hepatocyte culture by peroxisome proliferators
    • Bell, D.R., and Elcombe, C.R. 1991. Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in primary rat hepatocyte culture by peroxisome proliferators. Biochem. J. 280:249-253
    • (1991) Biochem. J , vol.280 , pp. 249-253
    • Bell, D.R.1    Elcombe, C.R.2
  • 118
    • 0028170146 scopus 로고
    • Dehydroepiandrosterone 3β-sulphate is an endogenous activator of the peroxisome-proliferation pathway: induction of cytochrome P-450 4A and acyl-CoA oxidase mRNAs in primary rat hepatocyte culture and inhibitory effects of Ca2+-channel blockers
    • Ram, P.A., and Waxman, D.J. 1994. Dehydroepiandrosterone 3β-sulphate is an endogenous activator of the peroxisome-proliferation pathway: induction of cytochrome P-450 4A and acyl-CoA oxidase mRNAs in primary rat hepatocyte culture and inhibitory effects of Ca2+-channel blockers. Biochem. J. 301:753-758
    • (1994) Biochem. J , vol.301 , pp. 753-758
    • Ram, P.A.1    Waxman, D.J.2
  • 119
    • 0027954043 scopus 로고
    • Activation of dehydroepiandrosterone as a peroxisome proliferator by sulfate conjugation
    • Yamada, J., Sakuma, M., Ikeda, T., and Suga, T. 1994. Activation of dehydroepiandrosterone as a peroxisome proliferator by sulfate conjugation. Arch. Biochem. Biophys. 313:379-381
    • (1994) Arch. Biochem. Biophys , vol.313 , pp. 379-381
    • Yamada, J.1    Sakuma, M.2    Ikeda, T.3    Suga, T.4
  • 120
    • 0028006797 scopus 로고
    • Specific binding of dehydroepiandrosterone sulfate to rat liver cytosol: a possible association with peroxisomal enzyme induction
    • Yamada, J., Sugiyama, H., Sakuma, M., and Suga, T. 1994. Specific binding of dehydroepiandrosterone sulfate to rat liver cytosol: a possible association with peroxisomal enzyme induction. Biochim. Biophys. Acta. 1224:139-146
    • (1994) Biochim. Biophys. Acta , vol.1224 , pp. 139-146
    • Yamada, J.1    Sugiyama, H.2    Sakuma, M.3    Suga, T.4
  • 121
    • 0027278522 scopus 로고
    • Positive regulation of the peroxisomal β-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
    • Dreyer, C., Keller, H., Mahfoudi, A., Laudet, V., Krey, G., and Wahli, W. 1993. Positive regulation of the peroxisomal β-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol. Cell. 77:67-76
    • (1993) Biol. Cell , vol.77 , pp. 67-76
    • Dreyer, C.1    Keller, H.2    Mahfoudi, A.3    Laudet, V.4    Krey, G.5    Wahli, W.6
  • 122
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • Gottlicher, M., Widmark, E., Li, Q., and Gustafsson, J.A. 1992. Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl. Acad. Sei. USA. 89:4653-4657
    • (1992) Proc. Natl. Acad. Sei. USA , vol.89 , pp. 4653-4657
    • Gottlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.A.4
  • 123
    • 0027415913 scopus 로고
    • Enantioselective activation of the peroxisome proliferator-activated receptor
    • Boie, Y., Adam, M., Rushmore, T.H., and Kennedy, B.P. 1993. Enantioselective activation of the peroxisome proliferator-activated receptor. J. Biol. Chem. 268:5530-5534
    • (1993) J. Biol. Chem , vol.268 , pp. 5530-5534
    • Boie, Y.1    Adam, M.2    Rushmore, T.H.3    Kennedy, B.P.4
  • 124
    • 0029856331 scopus 로고    scopus 로고
    • Role of metabolism in the activation of dehydroepiandrosterone as a peroxisome proliferator
    • Waxman, DJ. 1996. Role of metabolism in the activation of dehydroepiandrosterone as a peroxisome proliferator. J. Endocrinol. 150:S 129-S147
    • (1996) J. Endocrinol , vol.150 , pp. S129-S147
    • Waxman, D.J.1
  • 125
    • 0021060535 scopus 로고
    • Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds
    • Lalwani, N.D., Fahl, W.E., and Reddy, J.K. 1983. Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds. Biochem. Biophys. Res. Comm. 116:388-393
    • (1983) Biochem. Biophys. Res. Comm , vol.116 , pp. 388-393
    • Lalwani, N.D.1    Fahl, W.E.2    Reddy, J.K.3
  • 126
    • 0028997684 scopus 로고
    • Targeted disruption of the a isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S.S.-T., Pineau, T., Drago, J., Lee, E.J., Owens, J.W., Kroetz, D.L., Femandez-Salguero, P.M., Westphal, H., and Gonzalez, F.J. 1995. Targeted disruption of the a isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15:3012-3022
    • (1995) Mol. Cell. Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.-T.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Femandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 127
    • 0030452119 scopus 로고    scopus 로고
    • Targeted disruption of the peroxisome proliferator-activated receptor a gene, PPARa
    • Lee, S.S.T., and Gonzalez, F.J. 1996. Targeted disruption of the peroxisome proliferator-activated receptor a gene, PPARa. Ann. N. Y. Acad. Sei. 804:524-529
    • (1996) Ann. N. Y. Acad. Sei , vol.804 , pp. 524-529
    • Lee, S.S.T.1    Gonzalez, F.J.2
  • 128
    • 0030001343 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated recepter alpha required for gene induction by dehydroepiandrosterone-3β-sulfate
    • Peters, J.M., Zhou, Y.-C., Ram, P.A., Lee, S.S.T., Gonzalez, F.J., and Waxman, D.J. 1996. Peroxisome proliferator-activated recepter alpha required for gene induction by dehydroepiandrosterone-3β-sulfate. Mol. Pharmacol. 50:67-74
    • (1996) Mol. Pharmacol , vol.50 , pp. 67-74
    • Peters, J.M.1    Zhou, Y.-C.2    Ram, P.A.3    Lee, S.S.T.4    Gonzalez, F.J.5    Waxman, D.J.6
  • 129
    • 0025073306 scopus 로고
    • Characteristics of the suppressive effects of nicardipine on peroxisome induction in rat liver
    • Itoga, H., Tamura, H., Watanabe, T., and Suga, T. 1990. Characteristics of the suppressive effects of nicardipine on peroxisome induction in rat liver. Biochim. Biophys. Acta. 1051:21-28
    • (1990) Biochim. Biophys. Acta , vol.1051 , pp. 21-28
    • Itoga, H.1    Tamura, H.2    Watanabe, T.3    Suga, T.4
  • 130
    • 0026501068 scopus 로고
    • Reduction of rat liver endoplasmic reticulum Ca(2+)-ATPase activity and mobilization of hepatic intracellular calcium by ciprofibrate, a peroxisome proliferator
    • Bennett, A.M., and Williams, G.M. 1992. Reduction of rat liver endoplasmic reticulum Ca(2+)-ATPase activity and mobilization of hepatic intracellular calcium by ciprofibrate, a peroxisome proliferator. Biochem. Pharmacol. 43:595-605
    • (1992) Biochem. Pharmacol , vol.43 , pp. 595-605
    • Bennett, A.M.1    Williams, G.M.2
  • 131
    • 0027161689 scopus 로고
    • Alteration of rat liver endoplasmic reticulum Ca+2-ATPase thiol integrity by ciprofibrate, a peroxisome proliferator
    • Bennett, A.M., and Williams, G.M. 1993. Alteration of rat liver endoplasmic reticulum Ca+2-ATPase thiol integrity by ciprofibrate, a peroxisome proliferator. Biochem. Pharmacol. 45:2093-2098
    • (1993) Biochem. Pharmacol , vol.45 , pp. 2093-2098
    • Bennett, A.M.1    Williams, G.M.2
  • 132
    • 0026597699 scopus 로고
    • Phosphorylation of steroid hormone receptors
    • Orti, E., Bodwell, J.E., and Munck, A. 1992. Phosphorylation of steroid hormone receptors. Endocr. Rev. 13:105-128
    • (1992) Endocr. Rev , vol.13 , pp. 105-128
    • Orti, E.1    Bodwell, J.E.2    Munck, A.3
  • 133
  • 134
    • 0001414007 scopus 로고
    • Antioxidant mechanisms of enzymes and proteins
    • S. Ahmad, editor. New York:Chapman & Hall
    • Ahmad, S. 1995. Antioxidant mechanisms of enzymes and proteins. In Oxidative Stress and Antioxidant Defenses in Biology. S. Ahmad, editor. New York:Chapman & Hall. 238-272
    • (1995) In Oxidative Stress and Antioxidant Defenses in Biology , pp. 238-272
    • Ahmad, S.1
  • 136
    • 0025369970 scopus 로고
    • The measurement and mechanism of lipid peroxidation in biological systems
    • Gutteridge, J.M., and Halliwell, B. 1990. The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem. Sei. 15:129-135
    • (1990) Trends Biochem. Sei , vol.15 , pp. 129-135
    • Gutteridge, J.M.1    Halliwell, B.2
  • 137
    • 0027328852 scopus 로고
    • Protein oxidative damage is associated with life expectancy of houseflies
    • Sohal, R.S., Agarwal, S., Dubey, A., and Orr, W.C. 1993. Protein oxidative damage is associated with life expectancy of houseflies. Proc. Natl. Acad. Sei. USA. 90:7255-7259
    • (1993) Proc. Natl. Acad. Sei. USA , vol.90 , pp. 7255-7259
    • Sohal, R.S.1    Agarwal, S.2    Dubey, A.3    Orr, W.C.4
  • 138
    • 0026737695 scopus 로고
    • Oxidative damage to DNA in mammalian chromatin
    • Dizdaroglu, M. 1992. Oxidative damage to DNA in mammalian chromatin. Mutat. Res. 275:331-342
    • (1992) Mutat. Res , vol.275 , pp. 331-342
    • Dizdaroglu, M.1
  • 139
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman, D. 1956. Aging: A theory based on free radical and radiation chemistry. J. Gerontol. 11:298-300
    • (1956) J. Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 140
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman, K.B., and Ames, B.N. 1998. The free radical theory of aging matures. Physiol. Rev. 78:547-581
    • (1998) Physiol. Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 141
    • 0027053725 scopus 로고
    • Free radicals, antioxidants and ageing
    • Bunker, V.W. 1992. Free radicals, antioxidants and ageing. Med. Lab. Sei. 42:299-312
    • (1992) Med. Lab. Sei , vol.42 , pp. 299-312
    • Bunker, V.W.1
  • 143
  • 144
    • 0018836982 scopus 로고
    • Thiobarbituric acid value on fresh homogenate of rat as a parameter of lipid peroxidation in aging, CC14 intoxication, and vitamin E deficiency
    • Michara, M., Uchiyama, M., and Fukuzawa, K. 1980. Thiobarbituric acid value on fresh homogenate of rat as a parameter of lipid peroxidation in aging, CC14 intoxication, and vitamin E deficiency. Biochem. Med. 23:302-311
    • (1980) Biochem. Med , vol.23 , pp. 302-311
    • Michara, M.1    Uchiyama, M.2    Fukuzawa, K.3
  • 145
    • 0021322219 scopus 로고
    • Age dependent changes in lipids peroxide levels in the lipoprotein fractions of human serum
    • Hajihara, M., Nishigaki, I., Maseki, M., and Yaggi, K. 1984. Age dependent changes in lipids peroxide levels in the lipoprotein fractions of human serum. J. Gerontol. 39:269-272
    • (1984) J. Gerontol , vol.39 , pp. 269-272
    • Hajihara, M.1    Nishigaki, I.2    Maseki, M.3    Yaggi, K.4
  • 146
    • 0030828307 scopus 로고    scopus 로고
    • Constitutive activation of NF-κ in an animal model of aging
    • Spencer, N.F.L., Poynter, M.E., Im, S.-Y., and Daynes, R.A. 1997. Constitutive activation of NF-κ in an animal model of aging. Int. Immunol. 9:1581-1588
    • (1997) Int. Immunol , vol.9 , pp. 1581-1588
    • Spencer, N.F.L.1    Poynter, M.E.2    Im, S.-Y.3    Daynes, R.A.4
  • 147
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ and urine
    • Fraga, C.G., Shigenaga, M.K., Park, J.W., Degan, P., and Ames, B.N. 1990. Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ and urine. Proc. Natl. Acad. Sei. USA. 87: 4533-4537
    • (1990) Proc. Natl. Acad. Sei. USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.W.3    Degan, P.4    Ames, B.N.5
  • 148
    • 0000628634 scopus 로고
    • 7-methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection
    • Park, J.W., and Ames, B.N. 1988. 7-methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection. Proc. Natl. Acad. Sei. USA. 85: 7467-7470
    • (1988) Proc. Natl. Acad. Sei. USA , vol.85 , pp. 7467-7470
    • Park, J.W.1    Ames, B.N.2
  • 149
    • 0029800177 scopus 로고    scopus 로고
    • Fatty acid oxidation enzyme gene expression is downregulated in failing heart
    • Sack, M.N., Rader, T.A., Park, S., Bastin, J., McCune, S.A., and Kelly, D.P. 1996. Fatty acid oxidation enzyme gene expression is downregulated in failing heart. Circulation. 94:2837-2842
    • (1996) Circulation , vol.94 , pp. 2837-2842
    • Sack, M.N.1    Rader, T.A.2    Park, S.3    Bastin, J.4    McCune, S.A.5    Kelly, D.P.6
  • 150
    • 0029147191 scopus 로고
    • Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies
    • Sohal, R.S., Sohal, B.H., and Orr, W.C. 1995. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Rad. Biol, & Med. 19:499-504
    • (1995) Free Rad. Biol, & Med , vol.19 , pp. 499-504
    • Sohal, R.S.1    Sohal, B.H.2    Orr, W.C.3
  • 151
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • Schreck, R., Rieber, P., and Baeuerle, P.A. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10:2247-2248
    • (1991) EMBO J , vol.10 , pp. 2247-2248
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 152
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor kB activation in intact cells
    • Schreck, R., Meier, B., Maennel, D.N., Droege, W., and Baeuerle, P.A. 1992. Dithiocarbamates as potent inhibitors of nuclear factor kB activation in intact cells. J. Exp. Med. 175:1181-1194
    • (1992) J. Exp. Med , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Maennel, D.N.3    Droege, W.4    Baeuerle, P.A.5
  • 153
    • 0027974133 scopus 로고
    • Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κ
    • Schreck, R., and Baeuerle, P.A. 1994. Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κ. Methods Enzymol. 234:151-163
    • (1994) Methods Enzymol , vol.234 , pp. 151-163
    • Schreck, R.1    Baeuerle, P.A.2
  • 154
    • 0002574684 scopus 로고    scopus 로고
    • Reactive oxygen species as primary signals and second messengers in the activation of transcription factors
    • H. J. Forman, and E. Cadenas, editors. New York:Chapman & Hall
    • Schulze-Osthoff, K., Bauer, M., Vogt, M., Wesselborg, S., and Baeuerle, P.A. 1997. Reactive oxygen species as primary signals and second messengers in the activation of transcription factors. In Oxidative Stress and Signal Transduction. H. J. Forman, and E. Cadenas, editors. New York:Chapman & Hall. 239-259
    • (1997) In Oxidative Stress and Signal Transduction , pp. 239-259
    • Schulze-Osthoff, K.1    Bauer, M.2    Vogt, M.3    Wesselborg, S.4    Baeuerle, P.A.5
  • 155
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of gene transcription
    • Sen, C.K., and Packer, L. 1996. Antioxidant and redox regulation of gene transcription. FASEB J. 10: 709-720
    • (1996) FASEB J , vol.10 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 156
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P.A., and Henkel, T. 1994. Function and activation of NF-κB in the immune system. Ann. Rev. Immunol. 12:141-179
    • (1994) Ann. Rev. Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 157
    • 0029834145 scopus 로고    scopus 로고
    • Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-κ
    • Helenius, M., Hanninen, M., Lehtinen, S.K., and Salminen, A. 1996. Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-κ. Biochem. J. 318:603-608
    • (1996) Biochem. J , vol.318 , pp. 603-608
    • Helenius, M.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 158
    • 0029670391 scopus 로고    scopus 로고
    • Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-κB transcription factor in mouse cardial muscle
    • Helenius, H., Hanninen, M., Lehtinen, S.K., and Salminen, A. 1996. Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-κB transcription factor in mouse cardial muscle. J. Mol. Cell. Cardiol. 28:487-498
    • (1996) J. Mol. Cell. Cardiol , vol.28 , pp. 487-498
    • Helenius, H.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 159
    • 0030960606 scopus 로고    scopus 로고
    • Age-related changes in the regulation of transcription factor NF-κB in rat brain
    • Korhonen, P., Helenius, M., and Salminen, A. 1997. Age-related changes in the regulation of transcription factor NF-κB in rat brain. Neurosci. Lett. 225:61-64
    • (1997) Neurosci. Lett , vol.225 , pp. 61-64
    • Korhonen, P.1    Helenius, M.2    Salminen, A.3
  • 160
    • 0028985601 scopus 로고
    • Nuclear factor kB functions as a negative regulator for the rat androgen receptor gene and NF-κB activity increases during the age-dependent desensitization of the liver
    • Supakar, P.C., Jung, M.H., Song, C.S., Chatterjee, B., and Roy, A.K. 1995. Nuclear factor kB functions as a negative regulator for the rat androgen receptor gene and NF-κB activity increases during the age-dependent desensitization of the liver. J. Biol. Chem. 270:837-842
    • (1995) J. Biol. Chem , vol.270 , pp. 837-842
    • Supakar, P.C.1    Jung, M.H.2    Song, C.S.3    Chatterjee, B.4    Roy, A.K.5
  • 161
    • 0026747632 scopus 로고
    • Effect of aging and caloric restriction on intestinal permeability
    • Ma, T.Y., Hollander, D., Dadufalza, V., and Krugliak, P. 1992. Effect of aging and caloric restriction on intestinal permeability. Exp. Gerontol. 27:321-333
    • (1992) Exp. Gerontol , vol.27 , pp. 321-333
    • Ma, T.Y.1    Hollander, D.2    Dadufalza, V.3    Krugliak, P.4
  • 162
    • 0027162602 scopus 로고
    • Altered regulation of IL-6 production with normal aging: Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative
    • Daynes, R.A., Araneo, B.A., Ershler, W.B., Maloney, C., Li, G.-Z., and Ryu, S.-Y. 1993. Altered regulation of IL-6 production with normal aging: Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative. J. Immunol. 150:5219-5230
    • (1993) J. Immunol , vol.150 , pp. 5219-5230
    • Daynes, R.A.1    Araneo, B.A.2    Ershler, W.B.3    Maloney, C.4    Li, G.-Z.5    Ryu, S.-Y.6
  • 164
    • 0027503291 scopus 로고
    • Interleukin-6, a cytokine for gerontologists
    • Ershler, W.B. 1993. Interleukin-6, a cytokine for gerontologists. J. Am. Geriatr. Soc. 46:176-181
    • (1993) J. Am. Geriatr. Soc , vol.46 , pp. 176-181
    • Ershler, W.B.1
  • 165
    • 0029061968 scopus 로고
    • IL-2 and IL-6 secretion in dementia: Correlation with type and severity of disease
    • Huberman, M., Sredni, B., Stem, L., Kott, E., and Shalit, F. 1995. IL-2 and IL-6 secretion in dementia: Correlation with type and severity of disease. J. Neurol. Sei. 130:161-164
    • (1995) J. Neurol. Sei , vol.130 , pp. 161-164
    • Huberman, M.1    Sredni, B.2    Stem, L.3    Kott, E.4    Shalit, F.5
  • 166
    • 0029051259 scopus 로고
    • Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients
    • Huell, M., Strauss, S., Volk, B., Berger, M., and Bauer, J. 1995. Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol. 89: 544-551
    • (1995) Acta Neuropathol , vol.89 , pp. 544-551
    • Huell, M.1    Strauss, S.2    Volk, B.3    Berger, M.4    Bauer, J.5
  • 167
    • 0030913257 scopus 로고    scopus 로고
    • IL-12 directly stimulates expression of IL-10 by CD5+ B cells and IL-6 by both CD5+ and CD5 B cells: possible involvement in age-associated cytokine dysregulation
    • Spencer, N.F.L., and Daynes, R.A. 1996. IL-12 directly stimulates expression of IL-10 by CD5+ B cells and IL-6 by both CD5+ and CD5 B cells: possible involvement in age-associated cytokine dysregulation. Int. Immunol. 9:745-754
    • (1996) Int. Immunol , vol.9 , pp. 745-754
    • Spencer, N.F.L.1    Daynes, R.A.2
  • 168
    • 0001668516 scopus 로고
    • Interleukin-6
    • Second Edition. A. Thomson, editor. San Diego: Academic Press
    • Hirano, T. 1994. Interleukin-6. In The Cytokine Handbook, Second Edition. A. Thomson, editor. San Diego: Academic Press. 145-168
    • (1994) In The Cytokine Handbook , pp. 145-168
    • Hirano, T.1
  • 170
    • 0024319062 scopus 로고
    • Interleukin-6: Possible implications in human diseases
    • Hirano, T., and Kishimoto, T. 1989. Interleukin-6: Possible implications in human diseases. Ric. Clin. Lab. 19:1-10
    • (1989) Ric. Clin. Lab , vol.19 , pp. 1-10
    • Hirano, T.1    Kishimoto, T.2
  • 172
    • 0029045949 scopus 로고
    • The effect of nutritional status on cytokine and acute phase protein responses to elective surgery
    • Curtis, G.E., McAtear, C.A., Formela, L., Waish, A., and Shenkin, A. 1995. The effect of nutritional status on cytokine and acute phase protein responses to elective surgery. Cytokine. 7:380-388
    • (1995) Cytokine , vol.7 , pp. 380-388
    • Curtis, G.E.1    McAtear, C.A.2    Formela, L.3    Waish, A.4    Shenkin, A.5
  • 174
    • 0028080787 scopus 로고
    • Interleukin 6 potentiates priming with platelet activating factor.Arch
    • Biffl, W.L., Moore, E.E., Moore, F.A., Carl, V.S., Kim, F.J., and Franciose, R.J. 1994. Interleukin 6 potentiates priming with platelet activating factor.Arch. Surgery. 129:1131-1136
    • (1994) Surgery , vol.129 , pp. 1131-1136
    • Biffl, W.L.1    Moore, E.E.2    Moore, F.A.3    Carl, V.S.4    Kim, F.J.5    Franciose, R.J.6
  • 175
    • 0027964848 scopus 로고
    • Effects of interleukin 6 on megakaryocytes and on canine platelet function
    • Burstein, S.A. 1994. Effects of interleukin 6 on megakaryocytes and on canine platelet function. Stem Cells. 12:386-393
    • (1994) Stem Cells , vol.12 , pp. 386-393
    • Burstein, S.A.1
  • 176
    • 0029166052 scopus 로고
    • Role of cytokines in bone resorption
    • Manoiagas, S.C. 1995. Role of cytokines in bone resorption. Bone. 17:635-675
    • (1995) Bone , vol.17 , pp. 635-675
    • Manoiagas, S.C.1
  • 177
    • 0029973242 scopus 로고    scopus 로고
    • Immunoregulation by interleukin-12
    • Trinchieri, G., and Gerosa, F. 1996. Immunoregulation by interleukin-12. J. Leukocyte Biol. 59:505-511
    • (1996) J. Leukocyte Biol , vol.59 , pp. 505-511
    • Trinchieri, G.1    Gerosa, F.2
  • 179
    • 0027177864 scopus 로고
    • The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression
    • Ernst, D.N., Weigle, W.O., Noonan, D.J., McQuitty, D.N., and Hobbs, M.V. 1993. The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J. Immunol. 151:575-587
    • (1993) J. Immunol , vol.151 , pp. 575-587
    • Ernst, D.N.1    Weigle, W.O.2    Noonan, D.J.3    McQuitty, D.N.4    Hobbs, M.V.5
  • 180
    • 0031563145 scopus 로고    scopus 로고
    • Activation of NKl.l + Tcells in vitro and their possible role in age-associated changes in inducible IL-4 production
    • Poynter, M.E., Mu, H.H., Chen, X.P., and Daynes, R.A. 1997. Activation of NKl.l + Tcells in vitro and their possible role in age-associated changes in inducible IL-4 production. Cell. Immunol. 179:22-29
    • (1997) Cell. Immunol , vol.179 , pp. 22-29
    • Poynter, M.E.1    Mu, H.H.2    Chen, X.P.3    Daynes, R.A.4
  • 183
    • 0003025562 scopus 로고
    • Tumor necrosis factor-alpha
    • A. Thomson, editor. San Diego:Academic Press
    • Tracey, K.J. 1994. Tumor necrosis factor-alpha. In The Cytokine Handbook, Second Edition. A. Thomson, editor. San Diego:Academic Press. 289-304
    • (1994) In The Cytokine Handbook, Second Edition , pp. 289-304
    • Tracey, K.J.1
  • 184
    • 0027207242 scopus 로고
    • Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation
    • Beg, A.A., Finco, T.S., Nantermet, P.V., and Baldwin, A.S. 1993. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol. Cell. Biol. 13: 3301-3310
    • (1993) Mol. Cell. Biol , vol.13 , pp. 3301-3310
    • Beg, A.A.1    Finco, T.S.2    Nantermet, P.V.3    Baldwin, A.S.4
  • 185
    • 0030613758 scopus 로고    scopus 로고
    • NF-κ activation: the NOS kinase revealed?
    • Stancovski, I., and Baltimore, D. 1997. NF-κ activation: the NOS kinase revealed? Cell. 91:299-302
    • (1997) Cell , vol.91 , pp. 299-302
    • Stancovski, I.1    Baltimore, D.2
  • 186
    • 0030613646 scopus 로고    scopus 로고
    • Catalysis by a multiprotein IκB kinase complex
    • Maniatis, T. 1997. Catalysis by a multiprotein IκB kinase complex. Science. 278:818-819
    • (1997) Science , vol.278 , pp. 818-819
    • Maniatis, T.1
  • 187
    • 0343471402 scopus 로고    scopus 로고
    • TNF-α downregulates the peroxisome proliferator activated receptor-a and the mRNAs encoding peroxisomal proteins in rat liver
    • Beier, K., Volkl, A., and Fahimi, D. 1997. TNF-α downregulates the peroxisome proliferator activated receptor-a and the mRNAs encoding peroxisomal proteins in rat liver. FEBS Letters. 412:385-387
    • (1997) FEBS Letters , vol.412 , pp. 385-387
    • Beier, K.1    Volkl, A.2    Fahimi, D.3
  • 188
    • 0028305693 scopus 로고
    • The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor
    • Calandra, T., Bemhagen, J., Mitchell, R.A., and Bucala, R. 1994. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J. Exp. Med. 179: 1895-1902
    • (1994) J. Exp. Med , vol.179 , pp. 1895-1902
    • Calandra, T.1    Bemhagen, J.2    Mitchell, R.A.3    Bucala, R.4
  • 190
    • 14844366019 scopus 로고
    • Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF)
    • Mitchell, R., Bacher, M., Bernhagen, J., Pushkarskaya, T., Seidin, M.F., and Bucala, R. 1995. Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF). J. Immunol. 154:3863-3870
    • (1995) J. Immunol , vol.154 , pp. 3863-3870
    • Mitchell, R.1    Bacher, M.2    Bernhagen, J.3    Pushkarskaya, T.4    Seidin, M.F.5    Bucala, R.6
  • 191
    • 0029671119 scopus 로고    scopus 로고
    • Age-associated differences in TNF-a and nitric oxide production in endotoxic mice
    • Chorinchath, B.B., Kong, L.Y., Mao, L., and McCallum, R.E. 1996. Age-associated differences in TNF-a and nitric oxide production in endotoxic mice. J. Immunol. 156:1525-1530
    • (1996) J. Immunol , vol.156 , pp. 1525-1530
    • Chorinchath, B.B.1    Kong, L.Y.2    Mao, L.3    McCallum, R.E.4
  • 192
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
    • Ray, A., and Prefontaine, K.E. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl. Acad. Sei. USA. 91:752-756
    • (1994) Proc. Natl. Acad. Sei. USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 193
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R.I., Cogswell, P.C., Lofquist, A.K., and Jr., A.S.B. 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science. 270:283-286
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.A.S.B.3
  • 194
    • 0032489318 scopus 로고    scopus 로고
    • Transcriptional role of the nuclear factor kB site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells
    • Inoue, H., and Tanabe, T. 1998. Transcriptional role of the nuclear factor kB site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem. Biophys. Res. Comm. 244:143-148
    • (1998) Biochem. Biophys. Res. Comm , vol.244 , pp. 143-148
    • Inoue, H.1    Tanabe, T.2
  • 195
    • 0029595394 scopus 로고
    • Transcriptional roles of nuclear factor κB and nuclear factor-inretleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 c e l l s
    • Yamamoto, K., Arakawa, T., Ueda, N., and Yamamoto, S. 1995. Transcriptional roles of nuclear factor κB and nuclear factor-inretleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 c e l l s. / Biol. Chem. 270:31315-31320
    • (1995) / Biol. Chem , vol.270 , pp. 31315-31320
    • Yamamoto, K.1    Arakawa, T.2    Ueda, N.3    Yamamoto, S.4
  • 196
    • 0030608878 scopus 로고    scopus 로고
    • Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages
    • D'Acquisto, F., luvone, T., Rombola, L., Sautebin, L., Di Rosa, M., and Carnuccio, R. 1997. Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. F.E.B.S. Lett. 418:175-178
    • (1997) F.E.B.S. Lett , vol.418 , pp. 175-178
    • D'Acquisto, F.1    Luvone, T.2    Rombola, L.3    Sautebin, L.4    Di Rosa, M.5    Carnuccio, R.6
  • 197
    • 0031042274 scopus 로고    scopus 로고
    • Involvement of nuclear factor KB in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes
    • Crofford, L.J., Tan, B., McCarthy, C.J., and Hla, T. 1997. Involvement of nuclear factor KB in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes. Arthritis Rheum. 40: 226-236
    • (1997) Arthritis Rheum , vol.40 , pp. 226-236
    • Crofford, L.J.1    Tan, B.2    McCarthy, C.J.3    Hla, T.4
  • 198
    • 0025857560 scopus 로고
    • Prostaglandin endoperoxide synthase: regulation of enzyme expression
    • De Witt, D.L. 1991. Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim. Biophys. Acta. 1083:121-134
    • (1991) Biochim. Biophys. Acta , vol.1083 , pp. 121-134
    • De Witt, D.L.1
  • 199
    • 0022495136 scopus 로고
    • Vitamin B supplementation suppresses prostaglandin B synthesis and enhances the immune response of aged mice
    • Meydani, S.N., Meydani, M., Verdon, C.P., Shapiro, A.A., Blumberg, J.B., and Hayes, K.C. 1986. Vitamin B supplementation suppresses prostaglandin B synthesis and enhances the immune response of aged mice. Mech. Ageing Dev. 34:191-201
    • (1986) Mech. Ageing Dev , vol.34 , pp. 191-201
    • Meydani, S.N.1    Meydani, M.2    Verdon, C.P.3    Shapiro, A.A.4    Blumberg, J.B.5    Hayes, K.C.6
  • 200
    • 0028789676 scopus 로고
    • Antioxidants and immune response in aged persons: overview of present evidence
    • Meydani, S.N., Wu, D., Santos, M.S., and Hayek, M.G. 1995. Antioxidants and immune response in aged persons: overview of present evidence. Am. J. Clin. Nutr. 62(suppl): 1462S-1476S
    • (1995) Am. J. Clin. Nutr , vol.62 , pp. 1462S-1476S
    • Meydani, S.N.1    Wu, D.2    Santos, M.S.3    Hayek, M.G.4
  • 202
    • 0027989633 scopus 로고
    • Age differences in eicosanoid production of mouse splenocytes: effects on mitogen-induced T-cell proliferation
    • Hayek, M.G., Meydani, S.M., Meydani, M., and Blumberg, J.B. 1994. Age differences in eicosanoid production of mouse splenocytes: effects on mitogen-induced T-cell proliferation. J. Gerontol. 49:B197-B207
    • (1994) J. Gerontol , vol.49 , pp. B197-B207
    • Hayek, M.G.1    Meydani, S.M.2    Meydani, M.3    Blumberg, J.B.4
  • 203
    • 0344509627 scopus 로고    scopus 로고
    • Peroxide tone in eicosanoid signaling
    • H. J. Forman, and E. Cadenas, editors. New York:Chapman & Hall
    • Kulmacz, R.J., and Lands, W.E.M. 1997. Peroxide tone in eicosanoid signaling. In Oxidative Stress and Signal Transduction. H. J. Forman, and E. Cadenas, editors. New York:Chapman & Hall. 134-156
    • (1997) In Oxidative Stress and Signal Transduction , pp. 134-156
    • Kulmacz, R.J.1    Lands, W.E.M.2
  • 206
    • 0000474770 scopus 로고
    • Prevention and reversal of some age-associated changes in immunologic responses by supplemental dehydroepiandrosterone sulfate therapy
    • Daynes, R.A., and Araneo, B.A. 1992. Prevention and reversal of some age-associated changes in immunologic responses by supplemental dehydroepiandrosterone sulfate therapy. Aging: Immunol. & Infect. Dis. 3:135-154
    • (1992) Aging: Immunol. & Infect. Dis , vol.3 , pp. 135-154
    • Daynes, R.A.1    Araneo, B.A.2
  • 207
    • 0027412229 scopus 로고
    • Reversal of the immunosenescent phenotype by dehydroepiandrosterone: Hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant Hepatitis B surface antigen
    • Araneo, B.A., Woods, M.L., and Daynes, R.A. 1993. Reversal of the immunosenescent phenotype by dehydroepiandrosterone: Hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant Hepatitis B surface antigen. J. Infec. Dis. 167:830-840
    • (1993) J. Infec. Dis , vol.167 , pp. 830-840
    • Araneo, B.A.1    Woods, M.L.2    Daynes, R.A.3
  • 208
    • 0025923467 scopus 로고
    • Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon, but not IL-2 by activated murine B cells
    • Araneo, B.A., Dowell, T., Terui, T., Deigel, M., and Daynes, R.A. 1991. Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon, but not IL-2 by activated murine B cells. Blood. 78:688-699
    • (1991) Blood , vol.78 , pp. 688-699
    • Araneo, B.A.1    Dowell, T.2    Terui, T.3    Deigel, M.4    Daynes, R.A.5
  • 209
    • 0010620648 scopus 로고
    • Signal transduction pathways in T lymphocytes from old mice
    • Miller, R.A., Flurkey, K., and Patel, H. 1990. Signal transduction pathways in T lymphocytes from old mice. Aging: Immunol. & Infect. Dis. 2:97-103
    • (1990) Aging: Immunol. & Infect. Dis , vol.2 , pp. 97-103
    • Miller, R.A.1    Flurkey, K.2    Patel, H.3
  • 210
    • 85064934956 scopus 로고
    • Inhibition by isoptin (a calcium antagonist) of mitogenic stimulation of lymphocytes prior to the S-phase
    • Blitstein-Willinger, E., and Diamanstein, T. 1978. Inhibition by isoptin (a calcium antagonist) of mitogenic stimulation of lymphocytes prior to the S-phase. Immunol. 4:591-603
    • (1978) Immunol , vol.4 , pp. 591-603
    • Blitstein-Willinger, E.1    Diamanstein, T.2
  • 211
    • 0028848485 scopus 로고
    • Cellular disruption of protein kinase C isozymes in CD3-mediated stimulation of human T lymphocytes with aging
    • Fulop Jr., T., Leblanc, C., Lacombe, G., and Dupuis, G. 1995. Cellular disruption of protein kinase C isozymes in CD3-mediated stimulation of human T lymphocytes with aging. F.E.B.S. Lett. 375:69-74
    • (1995) F.E.B.S. Lett , vol.375 , pp. 69-74
    • Fulop, T.1    Leblanc, C.2    Lacombe, G.3    Dupuis, G.4
  • 212
    • 0028983621 scopus 로고
    • Differential expression of the alphaand beta-isoforms of protein kinase C in peripheral blood T and B cells from young and elderly adults
    • Whisler, R.L., Newhouse, Y.G., Grants, I.S., and Hackshaw, K.V. 1995. Differential expression of the alphaand beta-isoforms of protein kinase C in peripheral blood T and B cells from young and elderly adults. Mech. Ageing Dev. 77:197-211
    • (1995) Mech. Ageing Dev , vol.77 , pp. 197-211
    • Whisler, R.L.1    Newhouse, Y.G.2    Grants, I.S.3    Hackshaw, K.V.4
  • 213
    • 0026808781 scopus 로고
    • Tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice
    • Shi, J., and Miller, R.A. 1992. Tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice. J. Gerontol. 47:B147-B153
    • (1992) J. Gerontol , vol.47 , pp. B147-B153
    • Shi, J.1    Miller, R.A.2
  • 214
    • 0026571069 scopus 로고
    • Age-associated changes in mitogen-induced protein phosphorylation in murine T lymphocytes
    • Patel, H.R., and Miller, R.A. 1992. Age-associated changes in mitogen-induced protein phosphorylation in murine T lymphocytes. Eur. J. Immunol. 22:253-260
    • (1992) Eur. J. Immunol , vol.22 , pp. 253-260
    • Patel, H.R.1    Miller, R.A.2
  • 215
    • 0021982128 scopus 로고
    • Immunological studies of agein X. Impaired T lymphocytes and normal monocyte response from elderly humans to the mitogenic antibodies OKT3 and Leu 4
    • Schwab, R., Hausman, P.B., Rinnooy-Kan, E., and Weksler, M.E. 1985. Immunological studies of ageing. X. Impaired T lymphocytes and normal monocyte response from elderly humans to the mitogenic antibodies OKT3 and Leu 4. Immunol. 55:677-684
    • (1985) Immunol , vol.55 , pp. 677-684
    • Schwab, R.1    Hausman, P.B.2    Rinnooy-Kan, E.3    Weksler, M.E.4
  • 216
    • 0023893257 scopus 로고
    • Lymphocyte proliferative response to PHA and anti-CD-3/Ti monoclonal antibodies, B cell surface marker expression, and serum IL-2 receptor levels as biomarkers of age and health
    • Hallgren, H.M., Bergh, N., Rodysill, K.J., and O'Leary, J. 1988. Lymphocyte proliferative response to PHA and anti-CD-3/Ti monoclonal antibodies, B cell surface marker expression, and serum IL-2 receptor levels as biomarkers of age and health. Mech. Ageing Dev. 43:175-185
    • (1988) Mech. Ageing Dev , vol.43 , pp. 175-185
    • Hallgren, H.M.1    Bergh, N.2    Rodysill, K.J.3    O'Leary, J.4
  • 217
    • 0018561650 scopus 로고
    • B cell responsiveness in aging
    • Kay, M.M.B. 1979. B cell responsiveness in aging. Mech. Ageing Dev. 11:295-346
    • (1979) Mech. Ageing Dev , vol.11 , pp. 295-346
    • Kay, M.M.B.1
  • 218
    • 0015865379 scopus 로고
    • Decline in phytohemagglutinin responsiveness of spleen cells from aged mice
    • Hori, Y., Perkins, E.H., and Halsall, M.K. 1973. Decline in phytohemagglutinin responsiveness of spleen cells from aged mice. Proc. Soc. Exp. Biol. Med. 144:48-53
    • (1973) Proc. Soc. Exp. Biol. Med , vol.144 , pp. 48-53
    • Hori, Y.1    Perkins, E.H.2    Halsall, M.K.3
  • 219
    • 0015821513 scopus 로고
    • Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans
    • Hallgren, H.M., Buckley, C.E., Gilbertsen, V.A., and Yunis, E.J. 1973. Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans. J. Immunol. 111:1101-1107
    • (1973) J. Immunol , vol.111 , pp. 1101-1107
    • Hallgren, H.M.1    Buckley, C.E.2    Gilbertsen, V.A.3    Yunis, E.J.4
  • 220
    • 0017683159 scopus 로고
    • Immunological studies of aging III. Cytokinetic basis for the impaired response of lymphocytes from aged humans to plant lectins
    • Inkeles, B., Innes, J.B., Kuntz, M.M., Kadish, A.S., and Weksler, M.E. 1977. Immunological studies of aging. III. Cytokinetic basis for the impaired response of lymphocytes from aged humans to plant lectins. J. Exp. Med. 145:1176-1187
    • (1977) J. Exp. Med , vol.145 , pp. 1176-1187
    • Inkeles, B.1    Innes, J.B.2    Kuntz, M.M.3    Kadish, A.S.4    Weksler, M.E.5
  • 221
    • 0016765536 scopus 로고
    • Age-related changes in cell-mediated immunity in Balb/c mice
    • Walters, C.S., and Claman, H.N. 1975. Age-related changes in cell-mediated immunity in Balb/c mice. J. Immunol. 115:1438-1443
    • (1975) J. Immunol , vol.115 , pp. 1438-1443
    • Walters, C.S.1    Claman, H.N.2
  • 222
    • 0025088736 scopus 로고
    • Analysis of age-related degeneracy of T-cell repertoire: localized functional failure in CD8+ B cells
    • Sano, T.K., Asano, Y., and Tada, T. 1990. Analysis of age-related degeneracy of T-cell repertoire: localized functional failure in CD8+ B cells. Scand. J. Immunol. 32:545-553
    • (1990) Scand. J. Immunol , vol.32 , pp. 545-553
    • Sano, T.K.1    Asano, Y.2    Tada, T.3
  • 223
    • 0019410594 scopus 로고
    • Aging and antimicrobial immunity
    • Patel, P.J. 1981. Aging and antimicrobial immunity. J. Exp. Med. 154:821-831
    • (1981) J. Exp. Med , vol.154 , pp. 821-831
    • Patel, P.J.1
  • 224
    • 0017601503 scopus 로고
    • Diminished B cell surveillance function in old mice infected with lymphocyte choriomeningitis virus
    • Doherty, P.C. 1977. Diminished B cell surveillance function in old mice infected with lymphocyte choriomeningitis virus. Immunol. 32:751-754
    • (1977) Immunol , vol.32 , pp. 751-754
    • Doherty, P.C.1
  • 225
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Thl, Th2 and more
    • Mosmann, T.R., and Sad, S. 1996. The expanding universe of T-cell subsets: Thl, Th2 and more. Immunol. Today. 17:138-146
    • (1996) Immunol. Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 226
    • 0031014560 scopus 로고    scopus 로고
    • Functions of IL-4 and control of its expression
    • Brown, M.A., and Hural, J. 1997. Functions of IL-4 and control of its expression. Crit Rev Immunol. 17: 1-32
    • (1997) Crit Rev Immunol , vol.17 , pp. 1-32
    • Brown, M.A.1    Hural, J.2
  • 227
    • 0028177589 scopus 로고
    • CD4P0S, NK1 1P°S B cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
    • Yoshimoto, T., and Paul, W.E. 1994. CD4P0S, NK1. 1P°S B cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179:1285-1295
    • (1994) J. Exp. Med , vol.179 , pp. 1285-1295
    • Yoshimoto, T.1    Paul, W.E.2
  • 228
    • 15144357533 scopus 로고
    • Dysregulated production of cytokines by CD4+ B cell subsets from aging humans
    • Schwab, R., and Schmitt, K. 1983. Dysregulated production of cytokines by CD4+ B cell subsets from aging humans. J. Immunol. 150:33A
    • (1983) J. Immunol , vol.150 , pp. 33A
    • Schwab, R.1    Schmitt, K.2
  • 230
    • 0026640856 scopus 로고
    • Natural regulators of T-cell lymphokine production in vivo
    • Daynes, R.A., and Araneo, B.A. 1992. Natural regulators of T-cell lymphokine production in vivo. Journal of Immunotherapy. 12:174-179
    • (1992) Journal of Immunotherapy , vol.12 , pp. 174-179
    • Daynes, R.A.1    Araneo, B.A.2
  • 231
    • 0028224193 scopus 로고
    • Age and microenvironment-associated influences by PDGF on T-cell function
    • Wiedmeier, S.E., Mu, H.-H., Araneo, B.A., and Daynes, R.A. 1994. Age and microenvironment-associated influences by PDGF on T-cell function. J. Immunol. 152:3417-3426
    • (1994) J. Immunol , vol.152 , pp. 3417-3426
    • Wiedmeier, S.E.1    Mu, H.-H.2    Araneo, B.A.3    Daynes, R.A.4
  • 232
    • 0031058726 scopus 로고    scopus 로고
    • Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ B cells
    • Rincon, M., Anguita, J., Nakamura, T., Fikrig, E., and Flavell, R.A. 1997. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ B cells. J. Exp. Med. 185:461-469
    • (1997) J. Exp. Med , vol.185 , pp. 461-469
    • Rincon, M.1    Anguita, J.2    Nakamura, T.3    Fikrig, E.4    Flavell, R.A.5
  • 233
    • 0024325071 scopus 로고
    • The cellular and subcellular bases of immunosenescence
    • Thoman, M.L., and Weigle, W.O. 1989. The cellular and subcellular bases of immunosenescence. Adv. Immunol. 46:221-261
    • (1989) Adv. Immunol , vol.46 , pp. 221-261
    • Thoman, M.L.1    Weigle, W.O.2
  • 234
    • 0024916465 scopus 로고
    • B cell surface determinants and function in aging
    • Schwab, R., and Weksler, M.E. 1989. B cell surface determinants and function in aging. Immunol. Ser. 45:317-331
    • (1989) Immunol. Ser , vol.45 , pp. 317-331
    • Schwab, R.1    Weksler, M.E.2
  • 235
    • 0025870161 scopus 로고
    • Changing patterns of CD5+ CD20+ double positive lymphocytes with ageing and cytotoxic chemotherapy
    • Brohee, D., van Haeuerbeek, M., Kennes, B., and Neve, P. 1991. Changing patterns of CD5+ CD20+ double positive lymphocytes with ageing and cytotoxic chemotherapy. Mech. Ageing Dev. 58:127-138
    • (1991) Mech. Ageing Dev , vol.58 , pp. 127-138
    • Brohee, D.1    van Haeuerbeek, M.2    Kennes, B.3    Neve, P.4
  • 236
    • 0026713812 scopus 로고
    • Characterization of expanded populations of peritoneal CD5 B cells specific for phosphatidyl choline in old B10.H-2aH-4bp/Wts Mice
    • Booker, J.K., and Haughton, G. 1992. Characterization of expanded populations of peritoneal CD5 B cells specific for phosphatidyl choline in old B10.H-2aH-4bp/Wts Mice. Anw. N.Y.Acad. Sei. 651:494-497
    • (1992) Anw. N.Y.Acad. Sei , vol.651 , pp. 494-497
    • Booker, J.K.1    Haughton, G.2
  • 238
  • 239
    • 0026646723 scopus 로고
    • Characteristics and development of the murine B-lb (Ly-1 B sister) cell population
    • Stall, A.M., Adams, S., Herzenberg, L.A., and Kantor, A.B. 1992. Characteristics and development of the murine B-lb (Ly-1 B sister) cell population. Ann. N.Y.Acad. Sei. 651:33-43
    • (1992) Ann. N.Y.Acad. Sei , vol.651 , pp. 33-43
    • Stall, A.M.1    Adams, S.2    Herzenberg, L.A.3    Kantor, A.B.4
  • 240
    • 0026783772 scopus 로고
    • The Role of CD5+ B cells in the production of autoantibodies in murine systemic lupus erythematosus
    • Reap, E.A., Sobel, E.S., Cohen, P.L., and Eisenberg, R.A. 1992. The Role of CD5+ B cells in the production of autoantibodies in murine systemic lupus erythematosus. Ann. N. Y. Acad. Sei. 651:588-590
    • (1992) Ann. N. Y. Acad. Sei , vol.651 , pp. 588-590
    • Reap, E.A.1    Sobel, E.S.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 242
    • 0026726762 scopus 로고
    • Comparative evaluation of CD5 B cells in patients with rheumatoid arthritis and essential mixed cryoimmunoglobulinemia using FACS analyzer and FACSCAN flow cytometer
    • Xu, H.J., Roberts-Thomson, P.J., Ahern, M.J., and Aola, H. 1992. Comparative evaluation of CD5 B cells in patients with rheumatoid arthritis and essential mixed cryoimmunoglobulinemia using FACS analyzer and FACSCAN flow cytometer. Ann. N. Y. Acad. Sei. 651:594-598
    • (1992) Ann. N. Y. Acad. Sei , vol.651 , pp. 594-598
    • Xu, H.J.1    Roberts-Thomson, P.J.2    Ahern, M.J.3    Aola, H.4
  • 243
    • 0026038974 scopus 로고
    • Bcell chronic lymphocytic leukemia: present status and future directions
    • Dighiero, G., Travade, P., Chevret, S., Fenaux, P., Chastang, C., Binet, J.L., and CLL, T.F.C.G.O. 1991. Bcell chronic lymphocytic leukemia: present status and future directions. Blood. 78:1901-1914
    • (1991) Blood , vol.78 , pp. 1901-1914
    • Dighiero, G.1    Travade, P.2    Chevret, S.3    Fenaux, P.4    Chastang, C.5    Binet, J.L.C.L.L.6
  • 244
    • 0025864233 scopus 로고
    • CD5+ B cells and naturally occurring autoantibodies in cancer patients
    • Stein, R., Witz, I.P., Ovadia, J., Goldenberg, D.M., and Yron, I. 1991. CD5+ B cells and naturally occurring autoantibodies in cancer patients. Clin. Exp. Immunol. 85:418-423
    • (1991) Clin. Exp. Immunol , vol.85 , pp. 418-423
    • Stein, R.1    Witz, I.P.2    Ovadia, J.3    Goldenberg, D.M.4    Yron, I.5
  • 245
    • 0015071984 scopus 로고
    • Quantitative Immunoelectrophoresis of proteins in serum from a normal population: season-, age-, and sex-related variations
    • Lyngbye, J., and Kroll, J. 1971. Quantitative Immunoelectrophoresis of proteins in serum from a normal population: season-, age-, and sex-related variations. Clin. Chem. 17:495-500
    • (1971) Clin. Chem , vol.17 , pp. 495-500
    • Lyngbye, J.1    Kroll, J.2
  • 246
    • 0000610666 scopus 로고
    • Age related changes in serum immunoglobulin isotypes and isotype subclass levels among standard long-lived and autoimmune and immunodeficient strains of mice
    • Goidl, E.A., Stashak, P.N., Martin-McEvoy, S.J., and Hiernaux, J.R. 1988. Age related changes in serum immunoglobulin isotypes and isotype subclass levels among standard long-lived and autoimmune and immunodeficient strains of mice. Aging: Immunol. & Infect. Dis. 1:227-236
    • (1988) Aging: Immunol. & Infect. Dis , vol.1 , pp. 227-236
    • Goidl, E.A.1    Stashak, P.N.2    Martin-McEvoy, S.J.3    Hiernaux, J.R.4
  • 247
    • 0039119752 scopus 로고
    • Qualitative and quantitative analysis of autoantibody production in aging mice
    • Kato, K., and Hirokawa, K. 1993. Qualitative and quantitative analysis of autoantibody production in aging mice. Aging: Immunol. & Infect. Dis. 1:177-190
    • (1993) Aging: Immunol. & Infect. Dis , vol.1 , pp. 177-190
    • Kato, K.1    Hirokawa, K.2
  • 248
    • 0029998281 scopus 로고    scopus 로고
    • Dysregulation of IL-10production with aging: possible linkage to the age-associated decline in DHEA and its sulfated derivative
    • Spencer, N.F.L., Norton, S.D., Harrison, L.L., Li, G.Z., and Daynes, R.A. 1996. Dysregulation of IL-10production with aging: possible linkage to the age-associated decline in DHEA and its sulfated derivative. Exp. Gerontol. 31:393-408
    • (1996) Exp. Gerontol , vol.31 , pp. 393-408
    • Spencer, N.F.L.1    Norton, S.D.2    Harrison, L.L.3    Li, G.Z.4    Daynes, R.A.5
  • 249
    • 0024497811 scopus 로고
    • Minireview The cell biology of aging: immunological models
    • Miller, R.A. 1989. Minireview. The cell biology of aging: immunological models. J. Gerontol. 44:B4-B8
    • (1989) J. Gerontol , vol.44 , pp. B4-B8
    • Miller, R.A.1
  • 250
    • 0026334486 scopus 로고
    • Aging and immune function
    • Miller, R.A. 1991. Aging and immune function. Int. Rev. Cytol. 124:187-214
    • (1991) Int. Rev. Cytol , vol.124 , pp. 187-214
    • Miller, R.A.1
  • 251
    • 0030035583 scopus 로고    scopus 로고
    • The aging immune system: primer and prospectus
    • Miller, R.A. 1996. The aging immune system: primer and prospectus. Science. 273:70-74
    • (1996) Science , vol.273 , pp. 70-74
    • Miller, R.A.1
  • 253
    • 0024966011 scopus 로고
    • Pneumococcal polysaccharide vaccine
    • Immunization Practices Advisory Committee. 1989. Pneumococcal polysaccharide vaccine. Morbit. Mortal. Weekly Rep. 38:64-76
    • (1989) Morbit. Mortal. Weekly Rep , vol.38 , pp. 64-76
  • 254
    • 0002687447 scopus 로고
    • Experiences in the use and efficacy of inactivated influenza vaccine in nursing homes
    • A. P. Kendal, and P. A. Patriarca, editors. New York: Alan R. Loss, Inc
    • Arden, N.H., Patriarca, P.A., and Kendal, A.P. 1986. Experiences in the use and efficacy of inactivated influenza vaccine in nursing homes. In Options for the Control of Influenza. A. P. Kendal, and P. A. Patriarca, editors. New York: Alan R. Loss, Inc. 155-168
    • (1986) In Options for the Control of Influenza , pp. 155-168
    • Arden, N.H.1    Patriarca, P.A.2    Kendal, A.P.3
  • 255
    • 0018763782 scopus 로고
    • Different protection rates in various groups of volunteers given subunit influenza virus vaccine in 1976
    • Feery, B.J., Evered, M.G., and Morrison, E.I. 1979. Different protection rates in various groups of volunteers given subunit influenza virus vaccine in 1976. J. Infec. Dis. 139
    • (1979) J. Infec. Dis , pp. 139
    • Feery, B.J.1    Evered, M.G.2    Morrison, E.I.3
  • 256
    • 0020334815 scopus 로고
    • Serious morbidity and mortality associated with influenza epidemics
    • Glezen, W.P. 1982. Serious morbidity and mortality associated with influenza epidemics. Epidemiol. Rev. 4:25-44
    • (1982) Epidemiol. Rev , vol.4 , pp. 25-44
    • Glezen, W.P.1
  • 257
    • 0022424106 scopus 로고
    • Diptheria, tetanus and pertussis: guidelines for vaccine prophylaxis and other preventative measures
    • Immunization Practices Advisory Committee. 1985. Diptheria, tetanus and pertussis: guidelines for vaccine prophylaxis and other preventative measures. Morbit. Mortal. Weekly Rep. 34:405-414, 419-426
    • (1985) Morbit. Mortal. Weekly Rep , vol.34
  • 258
    • 0025714635 scopus 로고
    • Tetanus-United States, 1987 and 1988
    • Immunization Practices Advisory Committee. 1990. Tetanus-United States, 1987 and 1988. Morbit. Mortal. Weekly Rep. 39:37-41
    • (1990) Morbit. Mortal. Weekly Rep , vol.39 , pp. 37-41
  • 262
    • 0032560790 scopus 로고    scopus 로고
    • A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease Recombinant outer-surface protein A Lyme disease vaccine study consortium
    • Sigal, L.H., Zahradnik, J.M., Lavin, P., Patella, S.J., Bryant, G., Haselby, R., Hilton, E., Kunkel, M., Adler-Klein, D., Doherty, T., et al. 1998. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant outer-surface protein A Lyme disease vaccine study consortium. New Engl. J. Med. 339:216-222
    • (1998) New Engl. J. Med , vol.339 , pp. 216-222
    • Sigal, L.H.1    Zahradnik, J.M.2    Lavin, P.3    Patella, S.J.4    Bryant, G.5    Haselby, R.6    Hilton, E.7    Kunkel, M.8    Adler-Klein, D.9    Doherty, T.10
  • 263
    • 0032560842 scopus 로고    scopus 로고
    • Immunization against Lyme disease-an important first step
    • Steigbigel, R.T., and Benach, J.L. 1998. Immunization against Lyme disease-an important first step. New Engl. J. Med. 339:236-264
    • (1998) New Engl. J. Med , vol.339 , pp. 236-264
    • Steigbigel, R.T.1    Benach, J.L.2
  • 268
    • 0022657995 scopus 로고
    • Defective antimicrobial functions of oral secretions in the elderly
    • Ganguly, R., Stablein, J., Lockey, R.F., Shamblin, P., and Vargas, L. 1986. Defective antimicrobial functions of oral secretions in the elderly. J. Infec. Dis. 153:163-164
    • (1986) J. Infec. Dis , vol.153 , pp. 163-164
    • Ganguly, R.1    Stablein, J.2    Lockey, R.F.3    Shamblin, P.4    Vargas, L.5
  • 269
    • 0018899610 scopus 로고
    • Immune systems of human nasopharyngeal and palatine tonsils: histomorphometry of lymphoid components and quantification of immunoglobulin-producing cells in health and disease
    • Korsrud, F.R., and Brnadzaeg, P. 1980. Immune systems of human nasopharyngeal and palatine tonsils: histomorphometry of lymphoid components and quantification of immunoglobulin-producing cells in health and disease. Clin. Exp. Immunol. 39:361-370
    • (1980) Clin. Exp. Immunol , vol.39 , pp. 361-370
    • Korsrud, F.R.1    Brnadzaeg, P.2
  • 270
    • 0003661910 scopus 로고    scopus 로고
    • Annual, 1995 Section B: Causes of death, life tables and mortality trends., Geneva
    • World Health Organization. 1996. World Health Statistics, Annual, 1995. Section B: Causes of death, life tables and mortality trends., Geneva
    • (1996) World Health Statistics
  • 271
    • 0026644810 scopus 로고
    • Programming of lymphocyte responses to activation: extrinsic factors, provided microenvironmentally, confer flexibility and compartmentalization to T-cell function
    • R. L. Coffman, editor. Basel:Karger
    • Daynes, R.A., and Araneo, B.A. 1992. Programming of lymphocyte responses to activation: extrinsic factors, provided microenvironmentally, confer flexibility and compartmentalization to T-cell function. In Regulation and Functional Significance of T-Cell Subsets. R. L. Coffman, editor. Basel:Karger. 1-20
    • (1992) In Regulation and Functional Significance of T-Cell Subsets , pp. 1-20
    • Daynes, R.A.1    Araneo, B.A.2
  • 272
    • 0027013591 scopus 로고
    • Androstenediol regulates resistance against lethal infections in mice
    • Loria, R.M., and Padgett, D.A. 1992. Androstenediol regulates resistance against lethal infections in mice. Arch. Virol. 127:103-115
    • (1992) Arch. Virol , vol.127 , pp. 103-115
    • Loria, R.M.1    Padgett, D.A.2
  • 273
    • 0003417385 scopus 로고
    • Immune response facilitation and resistance to virus and bacterial infections with dehydroepiandrosterone (DHEA)
    • M. Kalimi, and W. Regelson, editors. New York: Walter de Gruyter
    • Loria, R.M., Regelson, W., and Padgett, D.A. 1990. Immune response facilitation and resistance to virus and bacterial infections with dehydroepiandrosterone (DHEA). In The Biologic Role of Dehydroepiandrosterone( DHEA). M. Kalimi, and W. Regelson, editors. New York: Walter de Gruyter. 107-130
    • (1990) In The Biologic Role of Dehydroepiandrosterone( DHEA) , pp. 107-130
    • Loria, R.M.1    Regelson, W.2    Padgett, D.A.3
  • 274
    • 0029855902 scopus 로고    scopus 로고
    • Regulation of the immune response by dehydroepiandrosterone and its metabolites
    • Loria, R.M., Padgett, D.A., and Huynh, P.N. 1996. Regulation of the immune response by dehydroepiandrosterone and its metabolites. J. Endocrinol. 150 Suppl:S209-S220
    • (1996) J. Endocrinol , vol.150 , pp. S209-S220
    • Loria, R.M.1    Padgett, D.A.2    Huynh, P.N.3
  • 275
    • 0029062228 scopus 로고
    • Effects of dehydroepiandrosterone in immunosuppressed adult mice infected with Cryptosporidium parvum
    • Rasmussen, K.R., Healey, M.C., Cheng, L., and Yang, S. 1995. Effects of dehydroepiandrosterone in immunosuppressed adult mice infected with Cryptosporidium parvum. J. Parasitol. 81:429-433
    • (1995) J. Parasitol , vol.81 , pp. 429-433
    • Rasmussen, K.R.1    Healey, M.C.2    Cheng, L.3    Yang, S.4
  • 276
    • 0026252319 scopus 로고
    • Effects of dexamethasone and dehydroepiandrosterone in immunosuppressed rats infected with Cryptosporidium parvum
    • Rasmussen, K.R., Martin, E.G., Arrowood, M.J., and Healey, M.C. 1991. Effects of dexamethasone and dehydroepiandrosterone in immunosuppressed rats infected with Cryptosporidium parvum. J. Protozool. 38:157S-159S
    • (1991) J. Protozool , vol.38 , pp. 157S-159S
    • Rasmussen, K.R.1    Martin, E.G.2    Arrowood, M.J.3    Healey, M.C.4
  • 277
    • 0026773917 scopus 로고
    • Dehydroepiandrosterone-induced regulation of Cryptosporidium parvum infections in aged Syrian golden hamsters
    • Rasmussen, K.R., and Healey, M.C. 1992. Dehydroepiandrosterone-induced regulation of Cryptosporidium parvum infections in aged Syrian golden hamsters. J. Parasitol. 78:554-557
    • (1992) J. Parasitol , vol.78 , pp. 554-557
    • Rasmussen, K.R.1    Healey, M.C.2
  • 278
    • 0026541501 scopus 로고
    • Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats
    • Rasmussen, K.R., Arrowood, M.J., and Healey, M.C. 1992. Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats. Antimicrob. Agents Chemother. 36:220-222
    • (1992) Antimicrob. Agents Chemother , vol.36 , pp. 220-222
    • Rasmussen, K.R.1    Arrowood, M.J.2    Healey, M.C.3
  • 279
    • 0025284590 scopus 로고
    • Regulation of murine lymphokine production II Dehydroepiandrosterone is natural enhancer of interleukin 2 synthesis by helper B cells
    • Daynes, R.A., Dudley, D.J., and Araneo, B.A. 1990. Regulation of murine lymphokine production II. Dehydroepiandrosterone is natural enhancer of interleukin 2 synthesis by helper B cells. Eur. J. Immunol. 20:793-802
    • (1990) Eur. J. Immunol , vol.20 , pp. 793-802
    • Daynes, R.A.1    Dudley, D.J.2    Araneo, B.A.3
  • 280
    • 0026091953 scopus 로고
    • Dehydroepiandrosterone enhances IL-2 production and cytotoxic effector function of human B cells
    • Suzuki, T., Suzuki, N., Daynes, R.A., and Engleman, E. 1991. Dehydroepiandrosterone enhances IL-2 production and cytotoxic effector function of human B cells. Clin. Immunol. Immunopathol. 61:202-211
    • (1991) Clin. Immunol. Immunopathol , vol.61 , pp. 202-211
    • Suzuki, T.1    Suzuki, N.2    Daynes, R.A.3    Engleman, E.4
  • 281
    • 0026737582 scopus 로고
    • Dehydroepiandrosterone protects mice from endotoxin toxicity and reduces tumor necrosis factor production
    • Danenberg, H.D., Alpert, G., Lustig, S., and Ben-Nathan, D. 1992. Dehydroepiandrosterone protects mice from endotoxin toxicity and reduces tumor necrosis factor production. Antimicrob. Agents Chemother. 36:2275-2279
    • (1992) Antimicrob. Agents Chemother , vol.36 , pp. 2275-2279
    • Danenberg, H.D.1    Alpert, G.2    Lustig, S.3    Ben-Nathan, D.4
  • 282
    • 85064931800 scopus 로고    scopus 로고
    • submitted. Restoration of normal mucosal immune responses in aged mice following supplementation with antioxidants or with specific activators of the PPARa transcription factor
    • Enioutina, E.Y., Poynter, M.E., Visic, D.M., and Daynes, R.A. submitted. Restoration of normal mucosal immune responses in aged mice following supplementation with antioxidants or with specific activators of the PPARa transcription factor. Int. Immunol
    • Int. Immunol
    • Enioutina, E.Y.1    Poynter, M.E.2    Visic, D.M.3    Daynes, R.A.4
  • 284
    • 0028058849 scopus 로고
    • The development of effective vaccine adjuvants employing natural regulators of T-cell lymphokine production in vivo
    • Daynes, R.A., and Araneo, B.A. 1994. The development of effective vaccine adjuvants employing natural regulators of T-cell lymphokine production in vivo. Ann. N. Y. Acad. Sei. 730:144-161
    • (1994) Ann. N. Y. Acad. Sei , vol.730 , pp. 144-161
    • Daynes, R.A.1    Araneo, B.A.2
  • 285
    • 0029930268 scopus 로고    scopus 로고
    • Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization
    • Daynes, R.A., Enioutina, E.Y., Butler, S., Mu, H.H., McGee, Z.A., and Araneo, B.A. 1996. Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization. Infect. Immun. 64:1100-1109
    • (1996) Infect. Immun , vol.64 , pp. 1100-1109
    • Daynes, R.A.1    Enioutina, E.Y.2    Butler, S.3    Mu, H.H.4    McGee, Z.A.5    Araneo, B.A.6
  • 286
    • 0028804990 scopus 로고
    • Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection
    • Danenberg, H.D., Ben-Yehuda, A., Zakay-Rones, Z., and Friedman, G. 1995. Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection. Vaccine. 13:1445-1448
    • (1995) Vaccine , vol.13 , pp. 1445-1448
    • Danenberg, H.D.1    Ben-Yehuda, A.2    Zakay-Rones, Z.3    Friedman, G.4
  • 287
    • 0030293905 scopus 로고    scopus 로고
    • The use of oral dehydroepiandrosterone sulfate as an adjuvant in tetanus and influenza vaccination of the elderly
    • Evans, T.G., Judd, M.E., Dowell, T., Poe, S., Daynes, R.A., and Araneo, B.A. 1996. The use of oral dehydroepiandrosterone sulfate as an adjuvant in tetanus and influenza vaccination of the elderly. Vaccine. 14:1531-1537
    • (1996) Vaccine , vol.14 , pp. 1531-1537
    • Evans, T.G.1    Judd, M.E.2    Dowell, T.3    Poe, S.4    Daynes, R.A.5    Araneo, B.A.6
  • 288
  • 289
    • 0030913803 scopus 로고    scopus 로고
    • The effect of DHEAS on influenza vaccination in aging adults
    • Degelau, J., Guay, D., and Hallgren, H. 1997. The effect of DHEAS on influenza vaccination in aging adults. J. Am. Geriatr. Soc. 45:747-751
    • (1997) J. Am. Geriatr. Soc , vol.45 , pp. 747-751
    • Degelau, J.1    Guay, D.2    Hallgren, H.3
  • 290
    • 0032524998 scopus 로고    scopus 로고
    • The influence of sequential annual vaccination and of DHEA administration on the efficacy of the immune response to influenza vaccine in the elderly
    • Ben-Yehuda, A., Danenberg, H.D., Zakay-Rones, Z., Gross, D.J., and Friedman, G. 1998. The influence of sequential annual vaccination and of DHEA administration on the efficacy of the immune response to influenza vaccine in the elderly. Mech. Ageing Dev. 102:299-306
    • (1998) Mech. Ageing Dev , vol.102 , pp. 299-306
    • Ben-Yehuda, A.1    Danenberg, H.D.2    Zakay-Rones, Z.3    Gross, D.J.4    Friedman, G.5
  • 291
    • 0030986512 scopus 로고    scopus 로고
    • Dehydroepiandrosterone treatment is not beneficial to the immune response to influenza in elderly subjects
    • Danenberg, H.D., Ben-Yehuda, A., Zakay-Rones, Z., Gross, D.J., and Friedman, G. 1997. Dehydroepiandrosterone treatment is not beneficial to the immune response to influenza in elderly subjects. J. Clin. Endocrinol. Metab. 82:2911-2914
    • (1997) J. Clin. Endocrinol. Metab , vol.82 , pp. 2911-2914
    • Danenberg, H.D.1    Ben-Yehuda, A.2    Zakay-Rones, Z.3    Gross, D.J.4    Friedman, G.5
  • 292
    • 0029555346 scopus 로고
    • Does DHEAS restore immune competence in aged animals through its capacity to function as a natural modulator of peroxisome activities? Ann
    • Spencer, N.F.L., Poynter, M.E., Hennebold, J.D., Mu, H.-H., and Daynes, R.A. 1995. Does DHEAS restore immune competence in aged animals through its capacity to function as a natural modulator of peroxisome activities? Ann. N. Y. Acad. Sei. 774:200-216
    • (1995) N. Y. Acad. Sei , vol.774 , pp. 200-216
    • Spencer, N.F.L.1    Poynter, M.E.2    Hennebold, J.D.3    Mu, H.-H.4    Daynes, R.A.5
  • 294
    • 0027477907 scopus 로고
    • Administration of dehydroepiandrosterone to burned mice preserves normal immunologic competence
    • Araneo, B.A., Shelby, J., Li, G.-Z., Ku, W., and Daynes, R.A. 1993. Administration of dehydroepiandrosterone to burned mice preserves normal immunologic competence. Arch. Surgery. 128:318-325
    • (1993) Arch. Surgery , vol.128 , pp. 318-325
    • Araneo, B.A.1    Shelby, J.2    Li, G.-Z.3    Ku, W.4    Daynes, R.A.5
  • 296
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-a-induced cell death
    • Beg, A.A., and Baltimore, D. 1996. An essential role for NF-κB in preventing TNF-a-induced cell death. Science. 274:782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 298
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • Wang, C.-Y., Mayo, M.W., and Baldwin, S.S. 1996. TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB. Science. 274:784-787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin, S.S.3
  • 299
    • 0027140283 scopus 로고
    • Unexpected expansions of CD8-bearing cells in old mice
    • Callahan, J.E., Kappler, J.W., and Marrack, P. 1993. Unexpected expansions of CD8-bearing cells in old mice. J. Immunol. 151:6657-6669
    • (1993) J. Immunol , vol.151 , pp. 6657-6669
    • Callahan, J.E.1    Kappler, J.W.2    Marrack, P.3
  • 300
    • 0024475129 scopus 로고
    • Pgp-lhi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A
    • Lerner, A., Yamada, T., and Miller, R.A. 1989. Pgp-lhi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A. Eur. J. Immunol. 19:977-982
    • (1989) Eur. J. Immunol , vol.19 , pp. 977-982
    • Lerner, A.1    Yamada, T.2    Miller, R.A.3
  • 301
    • 0025087733 scopus 로고
    • Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ B cells from young and aged mice
    • Ernst, D.N., Hobbs, M.V., Torbett, B.E., Glasebrook, A.L., Rehse, M.A., Bottomly, K., Hayakawa, K., Hardy, R.R., and Weigle, W.O. 1990. Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ B cells from young and aged mice. J. Immunol. 145:1295-12302
    • (1990) J. Immunol , vol.145 , pp. 1295-12302
    • Ernst, D.N.1    Hobbs, M.V.2    Torbett, B.E.3    Glasebrook, A.L.4    Rehse, M.A.5    Bottomly, K.6    Hayakawa, K.7    Hardy, R.R.8    Weigle, W.O.9
  • 302
    • 0025777388 scopus 로고
    • βl integrin (CD29) expression on human postnatal T cell subsets defined by selective CD45 isoform expression
    • Pilarski, L.M., Yacyshyn, B.R., Jensen, G.S., Pruski, E., and Pabst, H.F. 1991. βl integrin (CD29) expression on human postnatal T cell subsets defined by selective CD45 isoform expression. J. Immunol. 147:830-837
    • (1991) J. Immunol , vol.147 , pp. 830-837
    • Pilarski, L.M.1    Yacyshyn, B.R.2    Jensen, G.S.3    Pruski, E.4    Pabst, H.F.5
  • 303
    • 0029883688 scopus 로고    scopus 로고
    • Decreased susceptibility to copper-induced oxi dation of rat-lipoproteins after fibrate treatment: influence of fatty acid composition
    • Vazquez, M., Merlos, M., Adzet, T., and Laguna, J.C. 1996. Decreased susceptibility to copper-induced oxi dation of rat-lipoproteins after fibrate treatment: influence of fatty acid composition. Br. J. Pharmacol. 117:1155-1162
    • (1996) Br. J. Pharmacol , vol.117 , pp. 1155-1162
    • Vazquez, M.1    Merlos, M.2    Adzet, T.3    Laguna, J.C.4
  • 305
    • 0026689102 scopus 로고
    • Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies
    • Hoffman, R., Brook, G.J., and Aviram, M. 1992. Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies. Atherosclerosis. 93:105-113
    • (1992) Atherosclerosis , vol.93 , pp. 105-113
    • Hoffman, R.1    Brook, G.J.2    Aviram, M.3
  • 306
    • 0027444878 scopus 로고
    • Dehydroepiandrosterone pretreatment protects rats against the pro-oxidant and necrogenic effects of carbon tetrachloride
    • Aragno, M., Tamagno, E., Boccuzzi, G., Brignardello, E., Chiarpotto, E., Pizzini, A., and Danni, O. 1993. Dehydroepiandrosterone pretreatment protects rats against the pro-oxidant and necrogenic effects of carbon tetrachloride. Biochem. Pharmacol. 46:1689-1694
    • (1993) Biochem. Pharmacol , vol.46 , pp. 1689-1694
    • Aragno, M.1    Tamagno, E.2    Boccuzzi, G.3    Brignardello, E.4    Chiarpotto, E.5    Pizzini, A.6    Danni, O.7
  • 307
    • 0027212575 scopus 로고
    • Inhibition of macrophage superoxide generation by dehydroepiandrosterone
    • Mohan, P.F., and Jacobson, M.S. 1993. Inhibition of macrophage superoxide generation by dehydroepiandrosterone. Am. J. Med. Sei. 306:10-15
    • (1993) Am. J. Med. Sei , vol.306 , pp. 10-15
    • Mohan, P.F.1    Jacobson, M.S.2
  • 308
    • 0032486173 scopus 로고    scopus 로고
    • Bezafibrate has an antioxidant effect: peroxisome proliferator-activated receptor alpha is associated with Cu+2, Zn+2-superoxide dismutase in the liver
    • Inoue, I., Noji, S., Awata, T., Takahashi, K., Nakajima, T., Sonoda, M., Komoda, T., and Katamaya, S. 1998. Bezafibrate has an antioxidant effect: peroxisome proliferator-activated receptor alpha is associated with Cu+2, Zn+2-superoxide dismutase in the liver. Life Sei. 63:135-144
    • (1998) Life Sei , vol.63 , pp. 135-144
    • Inoue, I.1    Noji, S.2    Awata, T.3    Takahashi, K.4    Nakajima, T.5    Sonoda, M.6    Komoda, T.7    Katamaya, S.8
  • 310
    • 0031589571 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor a (PPARa) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level
    • Inoue, I., Noji, S., Shen, M., Takahashi, K., and Katayama, S. 1997. The peroxisome proliferator-activated receptor a (PPARa) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level. Biochem. Biophys. Res. Comm. 237:606-610
    • (1997) Biochem. Biophys. Res. Comm , vol.237 , pp. 606-610
    • Inoue, I.1    Noji, S.2    Shen, M.3    Takahashi, K.4    Katayama, S.5
  • 311
    • 0026746338 scopus 로고
    • Role of oxidative stress in Drosophila aging
    • Fleming, J.E., Reveillaud, I., and Niedzwiecki, A. 1992. Role of oxidative stress in Drosophila aging. Mutat. Res. 275:267-279
    • (1992) Mutat. Res , vol.275 , pp. 267-279
    • Fleming, J.E.1    Reveillaud, I.2    Niedzwiecki, A.3
  • 312
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr, W.C., and Sohal, R.S. 1994. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science. 263:1128-1130
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 313
    • 0031916865 scopus 로고    scopus 로고
    • Cross-talk between nuclear factor-kB and the steroid hormone receptors: mechanisms of mutual antagonism
    • McKay, L.I., and Cidlowski, J.A. 1998. Cross-talk between nuclear factor-kB and the steroid hormone receptors: mechanisms of mutual antagonism. Mol. Endocrin. 12:45-56
    • (1998) Mol. Endocrin , vol.12 , pp. 45-56
    • McKay, L.I.1    Cidlowski, J.A.2
  • 314
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J., and Glass, C.K. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature. 391:79-82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 315
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A.T., and Seed, B. 1998. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature. 391:82-86
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 316
    • 0000197851 scopus 로고    scopus 로고
    • α-Lipoic acid: a metabolic antioxidant and potential redox modulator of transcription
    • Packer, L., Roy, S., and Sen, C.K. 1997. α-Lipoic acid: a metabolic antioxidant and potential redox modulator of transcription. Adv. Pharmacol. 38:79-101
    • (1997) Adv. Pharmacol , vol.38 , pp. 79-101
    • Packer, L.1    Roy, S.2    Sen, C.K.3
  • 317
    • 0029931972 scopus 로고    scopus 로고
    • The orphan nuclear hormone receptor LXRa interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling
    • Miyata, K.S., McCaw, S.E., Patel, H.V., Rachubinski, R.A., and Capone, J.P. 1996. The orphan nuclear hormone receptor LXRa interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling. J. Biol. Chem. 271:9189-9192
    • (1996) J. Biol. Chem , vol.271 , pp. 9189-9192
    • Miyata, K.S.1    McCaw, S.E.2    Patel, H.V.3    Rachubinski, R.A.4    Capone, J.P.5
  • 318
    • 0032080237 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor-kB-mediated transactivations
    • Na, S.-Y., Lee, S.-K., Han, S.-J., Choi, H.-S., Im, S.-Y., and Lee, J.W. 1998. Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor-kB-mediated transactivations. J. Biol. Chem. 273:10831-10834
    • (1998) J. Biol. Chem , vol.273 , pp. 10831-10834
    • Na, S.-Y.1    Lee, S.-K.2    Han, S.-J.3    Choi, H.-S.4    Im, S.-Y.5    Lee, J.W.6
  • 319
    • 0027340413 scopus 로고
    • The impact of aging on enzyme proteins of rat liver peroxisomes: quantitative analysis by immunoblotting and immunoelectron microscopy
    • Beier, K., Volkl, M., and Fahimi, H.D. 1993. The impact of aging on enzyme proteins of rat liver peroxisomes: quantitative analysis by immunoblotting and immunoelectron microscopy. Virchows Arch. T Cell Pathol. 63:139-146
    • (1993) Virchows Arch. T Cell Pathol , vol.63 , pp. 139-146
    • Beier, K.1    Volkl, M.2    Fahimi, H.D.3
  • 320
    • 0028349162 scopus 로고
    • Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats
    • Nadiv, O., Shinitzky, M., Manu, H., Hecht, D., Roberts Jr, C.T., LeRoith, D., and Zick, Y. 1994. Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats. Biochem. J. 298:443-450
    • (1994) Biochem. J , vol.298 , pp. 443-450
    • Nadiv, O.1    Shinitzky, M.2    Manu, H.3    Hecht, D.4    Roberts, C.T.5    LeRoith, D.6    Zick, Y.7
  • 322
    • 0025766449 scopus 로고
    • Study on the lipid composition of aging Fischer-344 rat lymphoid cells: effect of long-term calorie restriction
    • Laganiere, S., and Femandes, G. 1991. Study on the lipid composition of aging Fischer-344 rat lymphoid cells: effect of long-term calorie restriction. Lipids. 26:472-478
    • (1991) Lipids , vol.26 , pp. 472-478
    • Laganiere, S.1    Femandes, G.2
  • 323
    • 0023262790 scopus 로고
    • Patterns of lipid changes in membranes of the aged brain
    • Shinitzky, M. 1987. Patterns of lipid changes in membranes of the aged brain. Gerontology. 33:149-154
    • (1987) Gerontology , vol.33 , pp. 149-154
    • Shinitzky, M.1
  • 324
    • 0019142887 scopus 로고
    • Age-dependence of molecular and functional changes in biological membrane properties
    • Hegner, D. 1980. Age-dependence of molecular and functional changes in biological membrane properties. Mech. Ageing Dev. 14:101-118
    • (1980) Mech. Ageing Dev , vol.14 , pp. 101-118
    • Hegner, D.1
  • 325
    • 0021812736 scopus 로고
    • Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats
    • Kamataki, T., Maeda, K., Shimada, M., Kitani, K., Nagai, T., and Kato, R. 1985. Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats. J. Pharmacol. Exp. Ther. 233:222-228
    • (1985) J. Pharmacol. Exp. Ther , vol.233 , pp. 222-228
    • Kamataki, T.1    Maeda, K.2    Shimada, M.3    Kitani, K.4    Nagai, T.5    Kato, R.6
  • 326
    • 0029060917 scopus 로고
    • Agerelated changes in the susceptibility to clofibric acid, a hypolipidemic agent, of male rat liver
    • Yamoto, T., Ohashi, Y., Teranishi, M., Takaoka, M., Manabe, S., Matsunuma, N., and Makita, T. 1995. Agerelated changes in the susceptibility to clofibric acid, a hypolipidemic agent, of male rat liver. Toxicol. Lett. 78:141-145
    • (1995) Toxicol. Lett , vol.78 , pp. 141-145
    • Yamoto, T.1    Ohashi, Y.2    Teranishi, M.3    Takaoka, M.4    Manabe, S.5    Matsunuma, N.6    Makita, T.7
  • 327
    • 18344418461 scopus 로고    scopus 로고
    • Aging-related decrease in liver peroxisomal fatty acid oxidation in control and clofibrate-treated mice A biochemical study and mechanistic approach
    • Perichon, R., and Bourre, J.M. 1996. Aging-related decrease in liver peroxisomal fatty acid oxidation in control and clofibrate-treated mice. A biochemical study and mechanistic approach. Mech. Ageing Dev. 87:115-126
    • (1996) Mech. Ageing Dev , vol.87 , pp. 115-126
    • Perichon, R.1    Bourre, J.M.2
  • 328
    • 0029552885 scopus 로고
    • Liver peroxisomal fatty acid oxidizing system during aging in control and Clofibrate treated mice
    • Perichon, R., and Bourre, J.M. 1995. Liver peroxisomal fatty acid oxidizing system during aging in control and Clofibrate treated mice. Biochem. and Mol. Biol. International. 37:475-480
    • (1995) Biochem. and Mol. Biol. International , vol.37 , pp. 475-480
    • Perichon, R.1    Bourre, J.M.2
  • 329
    • 0021380357 scopus 로고
    • Changes in the activities of peroxisomal, lysosomal, and mitochondrial enzymes of the rat in aging
    • Chandoga, J., Balaz, V., and Balazova, H. 1984. Changes in the activities of peroxisomal, lysosomal, and mitochondrial enzymes of the rat in aging. Bratisl. Lek. Listy. 81:176-181
    • (1984) Bratisl. Lek. Listy , vol.81 , pp. 176-181
    • Chandoga, J.1    Balaz, V.2    Balazova, H.3
  • 330
    • 0015606861 scopus 로고
    • Catalase turnover in rat liver and kidney as a function of age
    • Haining, J.L., and Legan, J.S. 1973. Catalase turnover in rat liver and kidney as a function of age. Exp. Gerontol. 8:85-91
    • (1973) Exp. Gerontol , vol.8 , pp. 85-91
    • Haining, J.L.1    Legan, J.S.2
  • 331
    • 0026723879 scopus 로고
    • Age-related alterations in antioxidant capacity and lipid peroxidation in brain, liver, and lung homogenates of normal and vitamin E-deficient rats
    • Matsuo, M., Gomi, F., and Dooley, M.M. 1992. Age-related alterations in antioxidant capacity and lipid peroxidation in brain, liver, and lung homogenates of normal and vitamin E-deficient rats. Mech. Ageing Dev. 64:273-292
    • (1992) Mech. Ageing Dev , vol.64 , pp. 273-292
    • Matsuo, M.1    Gomi, F.2    Dooley, M.M.3
  • 332
    • 0016718336 scopus 로고
    • The aging of rat liver as revealed by electron microscopic morphometry
    • Pieri, C., Zs.-Nagy, I., Mazzufferi, G., and Giuli, C. 1975. The aging of rat liver as revealed by electron microscopic morphometry. Exp. Gerontol. 10:291-304
    • (1975) Exp. Gerontol , vol.10 , pp. 291-304
    • Pieri, C.1    Zs-Nagy, I.2    Mazzufferi, G.3    Giuli, C.4
  • 333
    • 0025248785 scopus 로고
    • Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats
    • Rao, G., Xia, E., and Richardson, A. 1990. Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats. Mech. Ageing Dev. 53:49-60
    • (1990) Mech. Ageing Dev , vol.53 , pp. 49-60
    • Rao, G.1    Xia, E.2    Richardson, A.3
  • 334
    • 0024415301 scopus 로고
    • Changes in the expression of superoxide dismutase and catalase as a function of age and dietary restriction
    • Semsei, I., Rao, G., and Richardson, A. 1989. Changes in the expression of superoxide dismutase and catalase as a function of age and dietary restriction. Biochem. Biophys. Res. Comm. 164:620-625
    • (1989) Biochem. Biophys. Res. Comm , vol.164 , pp. 620-625
    • Semsei, I.1    Rao, G.2    Richardson, A.3
  • 335
    • 0025331369 scopus 로고
    • The influence of ageing on the induction of the mRNAs of rat liver cytochrome P450IIB1 and P450IIB2
    • Horbach, G.J., van Asten, J., G., and van Bezooijen, C.F.A. 1990. The influence of ageing on the induction of the mRNAs of rat liver cytochrome P450IIB1 and P450IIB2. Biochem. Pharmacol. 40:529-533
    • (1990) Biochem. Pharmacol , vol.40 , pp. 529-533
    • Horbach, G.J.1    van Asten, J.G.2    van Bezooijen, C.F.A.3
  • 336
    • 0029046136 scopus 로고
    • On the role of the peroxisome in ontogeny, ageing and degenerative disease
    • Masters, C.J., and Crane, D.I. 1995. On the role of the peroxisome in ontogeny, ageing and degenerative disease. Mech. Ageing Dev. 80:69-83
    • (1995) Mech. Ageing Dev , vol.80 , pp. 69-83
    • Masters, C.J.1    Crane, D.I.2
  • 337
    • 0028003839 scopus 로고
    • Regulation of the peroxisome proliferator-activated receptor a gene by glucocorticoids
    • Lemberger, T., Staels, B., Saladin, R., Desvergne, B., Auwerx, J., and Wahli, W. 1994. Regulation of the peroxisome proliferator-activated receptor a gene by glucocorticoids. J. Biol. Chem. 269:24527-24530
    • (1994) J. Biol. Chem , vol.269 , pp. 24527-24530
    • Lemberger, T.1    Staels, B.2    Saladin, R.3    Desvergne, B.4    Auwerx, J.5    Wahli, W.6
  • 338
    • 0030060358 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor a gene is stimulated by stress and follows a diumal rhythm
    • Lemberger, T., Saladin, R., Vasquez, M., Assimacopoulos, F., Staels, B., Desvergne, B., Wahli, W., and Auwerx, J. 1996. Expression of the peroxisome proliferator-activated receptor a gene is stimulated by stress and follows a diumal rhythm. J. Biol. Chem. 19:1764-1769
    • (1996) J. Biol. Chem , vol.19 , pp. 1764-1769
    • Lemberger, T.1    Saladin, R.2    Vasquez, M.3    Assimacopoulos, F.4    Staels, B.5    Desvergne, B.6    Wahli, W.7    Auwerx, J.8
  • 339
    • 0028131951 scopus 로고
    • Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells: Hormonal modulation of fatty-acidinduced transcription
    • Steineger, H.H., Sorensen, H.N., Tugwood, J.D., Skrede, S., Spydevold, O., and Gautvik, K.M. 1994. Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells: Hormonal modulation of fatty-acidinduced transcription. Eur. J. Biochem. 225:967-974
    • (1994) Eur. J. Biochem , vol.225 , pp. 967-974
    • Steineger, H.H.1    Sorensen, H.N.2    Tugwood, J.D.3    Skrede, S.4    Spydevold, O.5    Gautvik, K.M.6
  • 340
    • 0032546485 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor a (PPARa) in primary cultures of human vascular endothelial cells
    • Inoue, I., Shino, K., Noji, S., Awata, T., and Katayama, S. 1998. Expression of peroxisome proliferator-activated receptor a (PPARa) in primary cultures of human vascular endothelial cells. Biochem. Biophys. Res. Comm. 246:370-374
    • (1998) Biochem. Biophys. Res. Comm , vol.246 , pp. 370-374
    • Inoue, I.1    Shino, K.2    Noji, S.3    Awata, T.4    Katayama, S.5
  • 341
    • 0030057564 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor-alpha mRNA in rat liver
    • Sterchele, P.F., Sun, H., Peterson, R.E., and Vanden Heuvel, J.P. 1996. Regulation of peroxisome proliferator-activated receptor-alpha mRNA in rat liver. Arch. Biochem. Biophys. 326:281-289
    • (1996) Arch. Biochem. Biophys , vol.326 , pp. 281-289
    • Sterchele, P.F.1    Sun, H.2    Peterson, R.E.3    Vanden Heuvel, J.P.4
  • 342
    • 0023082847 scopus 로고
    • Increased response to peroxisomal proliferators in starved rats
    • Hertz, R., and Bar-Tana, J. 1987. Increased response to peroxisomal proliferators in starved rats. Biochim. Biophys. Acta. 917:57-61
    • (1987) Biochim. Biophys. Acta , vol.917 , pp. 57-61
    • Hertz, R.1    Bar-Tana, J.2
  • 343
    • 0031549576 scopus 로고    scopus 로고
    • Seminars in medicine of the Beath Israel Deaconess Medical Center
    • Weindruch, R., and Sohal, R.S. 1997. Seminars in medicine of the Beath Israel Deaconess Medical Center. Caloric intake and aging. New Engl. J. Med. 337:986-994
    • (1997) Caloric intake and aging. New Engl. J. Med , vol.337 , pp. 986-994
    • Weindruch, R.1    Sohal, R.S.2
  • 344
    • 0026605984 scopus 로고
    • Lipopolysaccharide-tumor necrosis factor-glucocorticoid interactions during cecal ligation and puncture-induced sepsis in mature versus senescent mice
    • Hyde, S.R., and McCallum, R.E. 1992. Lipopolysaccharide-tumor necrosis factor-glucocorticoid interactions during cecal ligation and puncture-induced sepsis in mature versus senescent mice. Infect. Immun. 60:976-982
    • (1992) Infect. Immun , vol.60 , pp. 976-982
    • Hyde, S.R.1    McCallum, R.E.2
  • 345
    • 0030038450 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced lethality and cytokine production in aged mice
    • Tateda, K., Matsumoto, T., Miyazaki, S., and Yamaguchi, K. 1996. Lipopolysaccharide-induced lethality and cytokine production in aged mice. Infect. Immun. 64:769-774
    • (1996) Infect. Immun , vol.64 , pp. 769-774
    • Tateda, K.1    Matsumoto, T.2    Miyazaki, S.3    Yamaguchi, K.4
  • 346
    • 0028365986 scopus 로고
    • Structure of the mouse peroxisome proliferator activated receptor a gene
    • Gearing, K.L., Crickmore, A., and Gustafsson, J.-A. 1994. Structure of the mouse peroxisome proliferator activated receptor a gene. Biochem. Biophys. Res. Comm. 199:255-263
    • (1994) Biochem. Biophys. Res. Comm , vol.199 , pp. 255-263
    • Gearing, K.L.1    Crickmore, A.2    Gustafsson, J.-A.3
  • 347
    • 0027968491 scopus 로고
    • The DNA-binding efficiency of Spl is affected by redox changes
    • Ammendola, R., Mesuraca, M., Russo, T., and Cimino, F. 1994. The DNA-binding efficiency of Spl is affected by redox changes. Eur. J. Biochem. 225:483-489
    • (1994) Eur. J. Biochem , vol.225 , pp. 483-489
    • Ammendola, R.1    Mesuraca, M.2    Russo, T.3    Cimino, F.4
  • 348
    • 0028795795 scopus 로고
    • DNA binding activity of the glucocorticoid receptor is sensitive to redox changes in intact cells
    • Esposito, F., Cuccovillo, F., Morra, F., Russo, T., and Cimino, F. 1995. DNA binding activity of the glucocorticoid receptor is sensitive to redox changes in intact cells. Biochim. Biophys. Acta. 1260:308-314
    • (1995) Biochim. Biophys. Acta , vol.1260 , pp. 308-314
    • Esposito, F.1    Cuccovillo, F.2    Morra, F.3    Russo, T.4    Cimino, F.5
  • 349
    • 0026644408 scopus 로고
    • Spl DNA binding efficiency is highly reduced in nuclear extracts from aged rat tissues./ Biol
    • Ammendola, R., Mesuraca, M., Russo, T., and Cimino, F. 1992. Spl DNA binding efficiency is highly reduced in nuclear extracts from aged rat tissues./ Biol. Chem. 267:17944-17948
    • (1992) Chem , vol.267 , pp. 17944-17948
    • Ammendola, R.1    Mesuraca, M.2    Russo, T.3    Cimino, F.4
  • 350
    • 0030827807 scopus 로고    scopus 로고
    • Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1 β, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes
    • Parmentier, J.H., Schohn, H., Bronner, M., Ferrari, L., Batt, A.M., Dauca, M., and Kremers, P. 1997. Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1 β, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes. Biochem. Pharmacol. 54:889-898
    • (1997) Biochem. Pharmacol , vol.54 , pp. 889-898
    • Parmentier, J.H.1    Schohn, H.2    Bronner, M.3    Ferrari, L.4    Batt, A.M.5    Dauca, M.6    Kremers, P.7
  • 351
    • 0027921994 scopus 로고
    • Neuroendocrine-immune interactions
    • Reichlin, S. 1993. Neuroendocrine-immune interactions. New Engl. J. Med. 329:1246-1253
    • (1993) New Engl. J. Med , vol.329 , pp. 1246-1253
    • Reichlin, S.1
  • 352
    • 0023574619 scopus 로고
    • Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin-1 in U937 cells
    • Knudsen, P.J., Dinarello, C.A., and Strom, T.B. 1987. Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin-1 in U937 cells. J. Immunol. 139:4129-4134
    • (1987) J. Immunol , vol.139 , pp. 4129-4134
    • Knudsen, P.J.1    Dinarello, C.A.2    Strom, T.B.3
  • 353
    • 0028156804 scopus 로고
    • Immune system-central nervous system interactions: effect and immunomodulatory consequences of immune system mediators on the brain
    • Black, P.H. 1994. Immune system-central nervous system interactions: effect and immunomodulatory consequences of immune system mediators on the brain. Antimicrob. Agents Chemother. 38:7-12
    • (1994) Antimicrob. Agents Chemother , vol.38 , pp. 7-12
    • Black, P.H.1
  • 354
    • 0022508713 scopus 로고
    • Control of cachectin (tumor necrosis factor) synthesis: mechanism of endotoxin resistance
    • Beutler, B., Krochin, N., Milsark, I.W., Luedke, C., and Cerami, A. 1986. Control of cachectin (tumor necrosis factor) synthesis: mechanism of endotoxin resistance. Science. 232:977-980
    • (1986) Science , vol.232 , pp. 977-980
    • Beutler, B.1    Krochin, N.2    Milsark, I.W.3    Luedke, C.4    Cerami, A.5
  • 355
    • 10144234128 scopus 로고    scopus 로고
    • Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene
    • Fan, C.-Y., Pan, J., Chu, R., Lee, D., Kluckman, K.D., Usuda, N., Singh, I., Yeldandi, A.V., Rao, M.S., Maeda, N., et al. 1996. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene. J. Biol. Chem. 271:24698-24710
    • (1996) J. Biol. Chem , vol.271 , pp. 24698-24710
    • Fan, C.-Y.1    Pan, J.2    Chu, R.3    Lee, D.4    Kluckman, K.D.5    Usuda, N.6    Singh, I.7    Yeldandi, A.V.8    Rao, M.S.9    Maeda, N.10
  • 356
    • 0032546929 scopus 로고    scopus 로고
    • Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase
    • Fan, C.-Y., Pan, J., Usuda, N., Yeldandi, A.V., Rao, M.S., and Reddy, J.K. 1998. Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. J. Biol. Chem. 273:15639-15645
    • (1998) J. Biol. Chem , vol.273 , pp. 15639-15645
    • Fan, C.-Y.1    Pan, J.2    Usuda, N.3    Yeldandi, A.V.4    Rao, M.S.5    Reddy, J.K.6
  • 357
    • 0040204710 scopus 로고    scopus 로고
    • Study of gene regulation by NF-κB and AP-1 in response to reactive oxygen intermediates
    • Muller, J.M., Rupee, R.A., and Baeuerle, P.A. 1997. Study of gene regulation by NF-κB and AP-1 in response to reactive oxygen intermediates. Methods. 11:301-312
    • (1997) Methods , vol.11 , pp. 301-312
    • Muller, J.M.1    Rupee, R.A.2    Baeuerle, P.A.3
  • 358
    • 0026661730 scopus 로고
    • Induction of the peroxisome proliferator-activated receptor by fenofibrate in rat liver
    • Gebel, T., Arand, M., and Oesch, F. 1992. Induction of the peroxisome proliferator-activated receptor by fenofibrate in rat liver. F.E.B.S. Lett. 309:37-40
    • (1992) F.E.B.S. Lett , vol.309 , pp. 37-40
    • Gebel, T.1    Arand, M.2    Oesch, F.3
  • 359
    • 0026045925 scopus 로고
    • Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate in the mouse skin in vivo
    • Furstenberger, G., Hagedorn, H., Jacobi, T., Besemfelder, E., Stephan, M., Lehmann, W.D., and Marks, F. 1991. Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate in the mouse skin in vivo. J. Biol. Chem. 266:15738-15745
    • (1991) J. Biol. Chem , vol.266 , pp. 15738-15745
    • Furstenberger, G.1    Hagedorn, H.2    Jacobi, T.3    Besemfelder, E.4    Stephan, M.5    Lehmann, W.D.6    Marks, F.7
  • 360
    • 0026079030 scopus 로고
    • Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin
    • Hughes, M.A., and Brash, A.R. 1991. Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin. Biochim. Biophys. Acta. 1081:347-354
    • (1991) Biochim. Biophys. Acta , vol.1081 , pp. 347-354
    • Hughes, M.A.1    Brash, A.R.2
  • 361
    • 0030827131 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin
    • Jisaka, M., Kim, R.B., Boeglin, W.E., Nanney, L.B., and Brash, A.R. 1997. Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin. J. Biol. Chem. 272: 24410-24416
    • (1997) J. Biol. Chem , vol.272 , pp. 24410-24416
    • Jisaka, M.1    Kim, R.B.2    Boeglin, W.E.3    Nanney, L.B.4    Brash, A.R.5
  • 362
    • 0032489383 scopus 로고    scopus 로고
    • cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin
    • Krieg, P., Kinzig, A., Heidt, M., Marks, F., and Furstenberger, G. 1998. cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin. Biochim. Biophys. Acta. 1391:7-12
    • (1998) Biochim. Biophys. Acta , vol.1391 , pp. 7-12
    • Krieg, P.1    Kinzig, A.2    Heidt, M.3    Marks, F.4    Furstenberger, G.5
  • 364
    • 0031691204 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptors by chlorinated hydrocarbons and endogenous steroid
    • Zhou, Y.-C., and Waxman, D.J. 1998. Activation of peroxisome proliferator-activated receptors by chlorinated hydrocarbons and endogenous steroids. Environ. Health Perspect. 106, Supplement 4:983-988
    • (1998) Environ. Health Perspect , vol.106 , pp. 983-988
    • Zhou, Y.-C.1    Waxman, D.J.2
  • 365
    • 0021691828 scopus 로고
    • Corticosteroid inhibition of ACTH secretion
    • Keller-Wood, M.E., and Dallman, M.F. 1984. Corticosteroid inhibition of ACTH secretion. Endocr. Rev. 5:1-24
    • (1984) Endocr. Rev , vol.5 , pp. 1-24
    • Keller-Wood, M.E.1    Dallman, M.F.2
  • 366
    • 0344103233 scopus 로고
    • Biosynthesis of adrenocortical steroids
    • Second Edition. V. H. T. James, editor. New York:Raven Press Ltd
    • Fräser, R. 1992. Biosynthesis of adrenocortical steroids. In The Adrenal Gland, Second Edition. V. H. T. James, editor. New York:Raven Press Ltd. 117-130
    • (1992) In The Adrenal Gland , pp. 117-130
    • Fräser, R.1
  • 367
    • 0025951111 scopus 로고
    • Adrenal androgen secretion and biologic effects
    • New aspects of adrenal cortical disease. D. H. Nelson, editor. Philadephia:W.B. Saunders Co
    • Meikle, W.A., Daynes, R.A., and Araneo, B.A. 1991. Adrenal androgen secretion and biologic effects. In Endocrinology and Metabolism Clinics of North America. New aspects of adrenal cortical disease. D. H. Nelson, editor. Philadephia:W.B. Saunders Co. 381-400
    • (1991) In Endocrinology and Metabolism Clinics of North America , pp. 381-400
    • Meikle, W.A.1    Daynes, R.A.2    Araneo, B.A.3
  • 368
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich, N., Brind, J.L., Rizer, R.L., and Vogelman, J.H. 1984. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J. Clin. Endocrinol. Metab. 59:551-555
    • (1984) J. Clin. Endocrinol. Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 369
    • 0031732983 scopus 로고    scopus 로고
    • Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence
    • Straub, R.H., Konecna, L., Hrach, S., Rothe, G., Kreutz, M., Scholmerich, J., Falk, W., and Lang, B. 1998. Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence. J. Clin. Endocrinol. Metab. 83:2012-2017
    • (1998) J. Clin. Endocrinol. Metab , vol.83 , pp. 2012-2017
    • Straub, R.H.1    Konecna, L.2    Hrach, S.3    Rothe, G.4    Kreutz, M.5    Scholmerich, J.6    Falk, W.7    Lang, B.8
  • 370
    • 0032539807 scopus 로고    scopus 로고
    • Detection of P450cl7-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells
    • Cascio, C., Prasad, V.V.K., Lin, Y.Y., Liberman, S., and Papadopoulos, V. 1998. Detection of P450cl7-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. Proc. Natl. Acad. Sei. USA. 95:2862-2867
    • (1998) Proc. Natl. Acad. Sei. USA , vol.95 , pp. 2862-2867
    • Cascio, C.1    Prasad, V.V.K.2    Lin, Y.Y.3    Liberman, S.4    Papadopoulos, V.5
  • 371
    • 0001686506 scopus 로고    scopus 로고
    • Immunological consequences of inhibiting dehydroepiandrosterone (DHEA) sulfatase in vivo
    • G. A. W. Rook, and S. Lightman, editors. Springer
    • Foulkes, R., Shaw, S., and Suitters, A. 1997. Immunological consequences of inhibiting dehydroepiandrosterone (DHEA) sulfatase in vivo. In Steroid Hormones and the T-Cell Cytokine profile. G. A. W. Rook, and S. Lightman, editors. Springer. 135-152
    • (1997) In Steroid Hormones and the T-Cell Cytokine profile , pp. 135-152
    • Foulkes, R.1    Shaw, S.2    Suitters, A.3
  • 372
  • 373
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and type II diabetes
    • Saltiel, A.R., and Olefsky, J.M. 1996. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 45:1661-1669
    • (1996) Diabetes , vol.45 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 374
    • 0022339852 scopus 로고
    • Hypoyhesis Glucose as a mediator of aging
    • Cerami, A. 1985. Hypoyhesis. Glucose as a mediator of aging. J. Am. Geriatr. Soc. 33:626-634
    • (1985) J. Am. Geriatr. Soc , vol.33 , pp. 626-634
    • Cerami, A.1
  • 375
    • 0029882670 scopus 로고    scopus 로고
    • The mechanism of collagen cross-linking in diabetes: a puzzle nearing resolution
    • Monnier, V.M., Glomb, M., Elgawish, A., and Sell, D.R. 1996. The mechanism of collagen cross-linking in diabetes: a puzzle nearing resolution. Diabetes. 45 Suppl:S67-S72
    • (1996) Diabetes , vol.45 , pp. S67-S72
    • Monnier, V.M.1    Glomb, M.2    Elgawish, A.3    Sell, D.R.4
  • 376
    • 0028068046 scopus 로고
    • Cellular receptors for glycation end products Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
    • Schmidt, A.M., Hon, O., Brett, J., Yan, S.D., Wautier, J.L., and Stern, D. 1994. Cellular receptors for glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions. Arteroscler. Thromb. 14:1521-1528
    • (1994) Arteroscler. Thromb , vol.14 , pp. 1521-1528
    • Schmidt, A.M.1    Hon, O.2    Brett, J.3    Yan, S.D.4    Wautier, J.L.5    Stern, D.6
  • 378
    • 0029088742 scopus 로고
    • Advanced glycation end products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice A potential mechanism for the accelerated vasculopathy of diabetes
    • Schmidt, A.M., Hori, O., Chen, J.X., Li, J.F., Crandall, J., Zhang, J., Cao, R., Yan, S.D., Brett, J., and Stern, D. 1995. Advanced glycation end products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J. Clin. Invest. 96:1395-1403
    • (1995) J. Clin. Invest , vol.96 , pp. 1395-1403
    • Schmidt, A.M.1    Hori, O.2    Chen, J.X.3    Li, J.F.4    Crandall, J.5    Zhang, J.6    Cao, R.7    Yan, S.D.8    Brett, J.9    Stern, D.10
  • 379
    • 0027176945 scopus 로고
    • Regulation of human mononuclear phagocyte migration and cell surface-binding proteins for advanced glycation end products
    • Schmidt, A.M., Yan, S.D., Brett, J., Mora, R., Nowygrod, R., and Stern, D. 1993. Regulation of human mononuclear phagocyte migration and cell surface-binding proteins for advanced glycation end products. J. Clin. Invest. 91:2155-2168
    • (1993) J. Clin. Invest , vol.91 , pp. 2155-2168
    • Schmidt, A.M.1    Yan, S.D.2    Brett, J.3    Mora, R.4    Nowygrod, R.5    Stern, D.6
  • 380
    • 0032540012 scopus 로고    scopus 로고
    • PPARa promotes monocyte/ macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., Nagy, L., Alvarez, J.G.A., Thomazy, V.A., and Evans, R.M. 1998. PPARa promotes monocyte/ macrophage differentiation and uptake of oxidized LDL. Cell. 93:241-252
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.A.3    Thomazy, V.A.4    Evans, R.M.5
  • 381
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARy
    • Nagy, L., Tontonoz, P., Alvarez, J.G.A., Chen, H., and Evans, R.M. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARy. Cell. 93:229-240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.A.3    Chen, H.4    Evans, R.M.5
  • 382
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner, E., Muller, C., Koshizuka, K., Williamson, E.A., Park, D., Asou, H., Shintaku, P., Said, J.W., Heber, D., and Koeffler, H.P. 1998. Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc. Natl. Acad. Sei. USA. 95:8806-8811
    • (1998) Proc. Natl. Acad. Sei. USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 383
    • 0023132442 scopus 로고
    • Aging and atherosclerosis
    • Stout, R.W. 1987. Aging and atherosclerosis. Age Aging. 16:65-72
    • (1987) Age Aging , vol.16 , pp. 65-72
    • Stout, R.W.1
  • 385
    • 0029984567 scopus 로고    scopus 로고
    • Coronary artery disease in the geriatric population
    • Keller, N.M., and Feit, F. 1996. Coronary artery disease in the geriatric population. Prog. Cardiovasc. Dis. 38:407-418
    • (1996) Prog. Cardiovasc. Dis , vol.38 , pp. 407-418
    • Keller, N.M.1    Feit, F.2
  • 386
    • 33749804551 scopus 로고
    • Cardiovascular disease
    • C.K. Cassel, D.E. Riesenberg, L.B. Sorensen, and J. R. Walsh, editors. New York:Springer-Verlag
    • Wenger, N.K. 1990. Cardiovascular disease. In Geriatric Medicine. C.K. Cassel, D.E. Riesenberg, L.B. Sorensen, and J. R. Walsh, editors. New York:Springer-Verlag. 152-163
    • (1990) In Geriatric Medicine , pp. 152-163
    • Wenger, N.K.1
  • 387
    • 0029397050 scopus 로고
    • Appraisal support predicts age-related differences in cardiovascular function in women
    • Uchino, B.N., Cacioppo, J.T., Malarkey, W., Glaser, R., and Kiecolt-Glaser, J.K. 1995. Appraisal support predicts age-related differences in cardiovascular function in women. Health Psychol. 14:556-562
    • (1995) Health Psychol , vol.14 , pp. 556-562
    • Uchino, B.N.1    Cacioppo, J.T.2    Malarkey, W.3    Glaser, R.4    Kiecolt-Glaser, J.K.5
  • 388
    • 0021043952 scopus 로고
    • Human myocardial histologic characteristics in congestive heart failure
    • Unverferth, D.V., Fetter, J.K., and Unverferth, J.B. 1983. Human myocardial histologic characteristics in congestive heart failure. Circulation. 68:1194-1200
    • (1983) Circulation , vol.68 , pp. 1194-1200
    • Unverferth, D.V.1    Fetter, J.K.2    Unverferth, J.B.3
  • 389
    • 0032565418 scopus 로고    scopus 로고
    • Altering molecular mechanisms to prevent sudden arrhythmic death
    • Henry, P.D., and Pacifico, A. 1998. Altering molecular mechanisms to prevent sudden arrhythmic death. Lancet. 351:1276-1278
    • (1998) Lancet , vol.351 , pp. 1276-1278
    • Henry, P.D.1    Pacifico, A.2
  • 390
    • 0014702860 scopus 로고
    • Increased glycolytic metabolism in cardiac hypertrophy and congestive failur
    • Bishop, S.P., and Altschuld, R.A. 1970. Increased glycolytic metabolism in cardiac hypertrophy and congestive failure. Am. 7. Physiol. 218:153-159
    • (1970) Am. 7. Physiol , vol.218 , pp. 153-159
    • Bishop, S.P.1    Altschuld, R.A.2
  • 391
    • 0023885409 scopus 로고
    • Effects of moderate hypertension on cardiac function and metabolism in the rabbit
    • Taegtmeyer, H., and Overturf, M.L. 1988. Effects of moderate hypertension on cardiac function and metabolism in the rabbit. Hypertension. 11:416-426
    • (1988) Hypertension , vol.11 , pp. 416-426
    • Taegtmeyer, H.1    Overturf, M.L.2
  • 392
    • 0027156410 scopus 로고
    • Cardiac hypertrophy and failure-a disease of adaption Modifications in membrane proteins provide a molecular basis for arrhythmogenicity
    • Moalic, J.M., Charlemagne, D., Mansier, P., Chevalier, B., and Swynghedauw, B. 1993. Cardiac hypertrophy and failure-a disease of adaption. Modifications in membrane proteins provide a molecular basis for arrhythmogenicity. Circulation. 87:IV21-IV26
    • (1993) Circulation , vol.87 , pp. IV21-IV26
    • Moalic, J.M.1    Charlemagne, D.2    Mansier, P.3    Chevalier, B.4    Swynghedauw, B.5
  • 394
    • 0029048043 scopus 로고
    • Effects of chronic right ventricular pressure overload on myocardial glucose and free fatty acid metabolism in the conscious rat
    • Takeyama, D., Kagaya, Y., Yamane, Y., Shiba, N., Chida, M., Takahashi, T., Ido, T., Ishide, N., and Takishima, T. 1995. Effects of chronic right ventricular pressure overload on myocardial glucose and free fatty acid metabolism in the conscious rat. Cardiovasc. Res. 29:763-767
    • (1995) Cardiovasc. Res , vol.29 , pp. 763-767
    • Takeyama, D.1    Kagaya, Y.2    Yamane, Y.3    Shiba, N.4    Chida, M.5    Takahashi, T.6    Ido, T.7    Ishide, N.8    Takishima, T.9
  • 396
    • 0027972866 scopus 로고
    • Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat
    • Christe, M.E., and Rodgers, R.L. 1994. Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat. J. Mol. Cell. Cardiol. 26:1371-1375
    • (1994) J. Mol. Cell. Cardiol , vol.26 , pp. 1371-1375
    • Christe, M.E.1    Rodgers, R.L.2
  • 397
    • 0030923761 scopus 로고    scopus 로고
    • A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program
    • Sack, M.N., Disch, D.L., Rockman, H.A., and Kelly, D.P. 1997. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. γ roc. Natl. Acad. Sei. USA. 94:6438-6443
    • (1997) γ roc. Natl. Acad. Sei. USA , vol.94 , pp. 6438-6443
    • Sack, M.N.1    Disch, D.L.2    Rockman, H.A.3    Kelly, D.P.4
  • 398
    • 0029939625 scopus 로고    scopus 로고
    • Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression
    • Disch, D.L., Rader, T.A., Cresci, S., Leone, T.C., Barger, P.M., Vega, R., Wood, P.A., and Kelly, D.P. 1996. Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression. Mol. Cell. Biol. 16: 4043-4051
    • (1996) Mol. Cell. Biol , vol.16 , pp. 4043-4051
    • Disch, D.L.1    Rader, T.A.2    Cresci, S.3    Leone, T.C.4    Barger, P.M.5    Vega, R.6    Wood, P.A.7    Kelly, D.P.8
  • 400
    • 0030849674 scopus 로고    scopus 로고
    • Adipose tissue-derived tumor necrosis factor-alpha activity is elevated in older rats
    • Morin, C.L., Pagliassotti, M.J., Windmiller, D., and Eckel, R.H. 1997. Adipose tissue-derived tumor necrosis factor-alpha activity is elevated in older rats. J Gerontol A Biol Sei Med Sei. 52:B 190-B195
    • (1997) J Gerontol A Biol Sei Med Sei , vol.52 , pp. B190-B195
    • Morin, C.L.1    Pagliassotti, M.J.2    Windmiller, D.3    Eckel, R.H.4
  • 401
    • 0025140914 scopus 로고
    • Short-term effects of dehydroepiandrosterone treatment in rats with diet-induced obesity
    • Mohan, P.F., and Cleary, M.P. 1991. Short-term effects of dehydroepiandrosterone treatment in rats with diet-induced obesity. J. Nutr. 120:1103-1114
    • (1991) J. Nutr , vol.120 , pp. 1103-1114
    • Mohan, P.F.1    Cleary, M.P.2
  • 402
    • 0018757962 scopus 로고
    • Inhibition of spontaneous breast cancer formation in female C3H (Avy/a) mice by long term treatment with DHEA
    • Schwartz, A.G. 1979. Inhibition of spontaneous breast cancer formation in female C3H (Avy/a) mice by long term treatment with DHEA. Cancer Res. 39:1129-1132
    • (1979) Cancer Res , vol.39 , pp. 1129-1132
    • Schwartz, A.G.1
  • 403
    • 0017405467 scopus 로고
    • Prevention of obesity in Avy/a mice by DHEA
    • Yen, T.T., Allan, J.A., and Pearson, D.V. 1977. Prevention of obesity in Avy/a mice by DHEA. Lipids. 12:409-413
    • (1977) Lipids , vol.12 , pp. 409-413
    • Yen, T.T.1    Allan, J.A.2    Pearson, D.V.3
  • 404
    • 0025321619 scopus 로고
    • Reduction in body weight and cholesterol in spontaneously obese dogs by dehydroepiandrosterone
    • Kurziman, I.D., Macewen, E.G., and Haffa, A.L.M. 1990. Reduction in body weight and cholesterol in spontaneously obese dogs by dehydroepiandrosterone. Intl. J. Obes. 14:95-104
    • (1990) Intl. J. Obes , vol.14 , pp. 95-104
    • Kurziman, I.D.1    Macewen, E.G.2    Haffa, A.L.M.3
  • 405
    • 0345695377 scopus 로고
    • Obesity in the dog: role of the adrenal steroid dehydroepiandrosterone (DHEA)
    • MacEwen, E.G., and Kurzman, I.D. 1991. Obesity in the dog: role of the adrenal steroid dehydroepiandrosterone (DHEA). J. Nutr. 121 :S51-S55
    • (1991) J. Nutr , vol.121 , pp. S51-S55
    • MacEwen, E.G.1    Kurzman, I.D.2
  • 407
    • 0022441760 scopus 로고
    • Anti-obesity effect of two different levels of dehydroepiandrosterone in lean and middle-aged Zucker rats
    • Cleary, M.P, and Zisk, J.F. 1986. Anti-obesity effect of two different levels of dehydroepiandrosterone in lean and middle-aged Zucker rats. Intl. J. Obes. 10:193-204
    • (1986) Intl. J. Obes , vol.10 , pp. 193-204
    • Cleary, M.P.1    Zisk, J.F.2
  • 409
    • 0030000385 scopus 로고    scopus 로고
    • The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
    • Breitner, J.C. 1996. The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu. Rev. Med. 47:401-411
    • (1996) Annu. Rev. Med , vol.47 , pp. 401-411
    • Breitner, J.C.1
  • 410
    • 0030250376 scopus 로고    scopus 로고
    • Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: a current appraisal
    • Breitner, J.C. 1996. Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: a current appraisal. Neurobiol. Aging. 17:789-794
    • (1996) Neurobiol. Aging , vol.17 , pp. 789-794
    • Breitner, J.C.1
  • 411
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies
    • McGeer, PL., Schulzer, M., and McGeer, E.G. 1996. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology. 47:425-432
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1    Schulzer, M.2    McGeer, E.G.3
  • 412
    • 0021745997 scopus 로고
    • Steroid sulfatase and 17β-hydroxysteroid oxidoreductase activities in mouse tissues
    • Milewich, L., Garcia, R.L., and Gerrity, L.W. 1984. Steroid sulfatase and 17β-hydroxysteroid oxidoreductase activities in mouse tissues. J. Steroid Biochem. 21:529-538
    • (1984) J. Steroid Biochem , vol.21 , pp. 529-538
    • Milewich, L.1    Garcia, R.L.2    Gerrity, L.W.3
  • 413
    • 0025318862 scopus 로고
    • Regulation of murine lymphokine production in vivo III The lymphoid tissue microenvironment exerts regulatory over T cell function
    • Daynes, R.A., Araneo, B.A., Dowell, T.A., Huang, K., and Dudley, D. 1990. Regulation of murine lymphokine production in vivo III. The lymphoid tissue microenvironment exerts regulatory over T cell function. J. Exp. Med. 171:979-996
    • (1990) J. Exp. Med , vol.171 , pp. 979-996
    • Daynes, R.A.1    Araneo, B.A.2    Dowell, T.A.3    Huang, K.4    Dudley, D.5
  • 414
    • 0028302689 scopus 로고
    • Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines
    • Hennebold, J.D., and Daynes, R.D. 1994. Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines. Endocrinol. 135:67-75
    • (1994) Endocrinol , vol.135 , pp. 67-75
    • Hennebold, J.D.1    Daynes, R.D.2
  • 415
    • 0024401919 scopus 로고
    • Purification and characterization of human liver dehydroepiandrosterone sulphotransferase
    • Falany, C.N., Vazquez, M.E., and Kalb, J.M. 1989. Purification and characterization of human liver dehydroepiandrosterone sulphotransferase. Biochem. J. 260:641-646
    • (1989) Biochem. J , vol.260 , pp. 641-646
    • Falany, C.N.1    Vazquez, M.E.2    Kalb, J.M.3


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