Involvement of nuclear factor κB in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes

Arthritis and Rheumatism

Volumn 40, Issue 2, 1997, Pages 226-236

  Crofford, Leslie J ^a,c   Tan, Bing ^a   McCarthy, Conor J ^a   Hla, Timothy ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HOLLAND LABORATORY   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA;

ARTICLE; ELECTROPHORETIC MOBILITY; ENZYME ASSAY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; ELECTROPHORESIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-1; NF-KAPPA B; OLIGONUCLEOTIDES, ANTISENSE; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; SYNOVIAL MEMBRANE; TIME FACTORS; TRANSCRIPTION FACTOR RELA;

EID: 0031042274     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400207     Document Type: Article

References (50)

1. Salmon JA, Higgs GA, Vane JR, Bitensky L, Chayen J, Henderson B, Cashman B: Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. Ann Rheum Dis 42:36-39, 1983
2. Davies P, Bailey PJ, Goldenberg MM, Ford-Hutchinson AW: The role of arachidonic acid oxygenation products in pain and inflammation. Annu Rev Immunol 2:335-357, 1984
3. Dayer J-M, Robinson DR, Krane SM: Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear cells. J Exp Med 145:1399-1404, 1977
4. Dayer J-M, de Rochemontiew B, Burrus B, Demczuk S, Dinarello CA: Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest 77:645-648, 1986
5. Robinson DR, Tashijian AHJ, Levine L: Prostaglandin-stimulated bone resorption by rheumatoid synovia: a possible mechanism for bone destruction in rheumatoid arthritis. J Clin Invest 56:1181-1188, 1975
6. Dayer J-M, Krane SM, Russell RGG, Robinson DR: Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc Natl Acad Sci U S A 73:945-949, 1976
7. Ben-Av P, Crofford LJ, Wilder RL, Hla T: Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis. FEBS Lett 372:83-87, 1995
8. Flower RJ, Blackwell GJ: The importance of phospholipase A2 in prostaglandin biosynthesis. Biochem Pharmacol 25:285-291, 1976
9. Gilman SC, Chang J, Zeigler PR, Uhl J, Mochan H: Interleukin-1 activates phospholipase A2 in human synovial cells. Arthritis Rheum 31:126-130, 1988
10. DeWitt DL: Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim Biophys Acta 1083:121-134, 1991
11. Kubuju DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR: TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 266:12866-12872, 1991
12. O'Banion MK, Sadowski HB, Winn V, Young DA: A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J Biol Chem 266:23261-23267, 1991
13. Kujubu DA, Herschman HR: Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J Biol Chem 267:7991-7994, 1992
14. O'Sullivan MG, Huggins EMJ, Meade EA, DeWitt DL, McCall CE: Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages. Biochem Biophys Res Comm 187:1123-1127, 1992
15. O'Sullivan MG, Chilton FH, Huggins EMJ, McCall CE: Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase. J Biol Chem 267:14547-14550, 1992
16. Crofford LJ, Wilder RL, Ristimaki AP, Remmers EF, Epps HR, Hla T: Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues: effects of interleukin-lβ, phorbol ester, and corticosteroids. J Clin Invest 93:1095-1101, 1994
17. 2. Arthritis Rheum 37:653-661, 1994
18. Sano H, Hla T, Maier JAM, Crofford LJ, Case JP, Maciag T, Wilder RL: In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. J Clin Invest 89:97-108, 1992
19. Arend WP, Dayer J-M: Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 33:305-315, 1990
20. Eastgate JA, Symons JA, Wood NC, Grinlinton FM, di Giovine FS, Duff GW: Correlation of plasma interleukin-1 levels with disease activity in rheumatoid arthritis. Lancet 2:706-709, 1988
21. Bucala R, Ritchlin C, Winchester R, Cerami A: Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts. J Exp Med 173:569-574, 1991
22. Andreis M, Stastny P, Ziff M: Experimental arthritis produced by mediators of delayed hypersensitivity. Arthritis Rheum 17:537-551, 1974
23. Feige U, Karbowski A, Rordorf-Adam C, Pataki A: Arthritis induced by continuous infusion of hr-interleukin-la into the rabbit knee-joint. Int J Tissue React 11:225-238, 1989
24. Sims JE, Gaylc MA, Slack JL, Alderson MR, Bird TA, Giri JG, Colotta F, Re F, Mantovani A, Shanebeck K, Grabstein KH, Dower SK: Interlcukin 1 signaling occurs exclusively via the type I receptor. Proc Natl Acad Sci U S A 90:6155-6159, 1993
25. Sims JE, Giri JG, Dower SK: The two interleukin-1 receptors play different roles in IL-1 actions. Clin Immunol Immunopathol 72:944, 1994
26. Dinarello CA: The interleukin-1 family: 10 years of discovery. FASEB J 8:1314-1325, 1994
27. Kuno K, Matsushima K: The IL-1 receptor signaling pathway. J Leukocyte Biol 56:542-547, 1994
28. Beg AA, Baldwin AS Jr: The IKB proteins: multifunctional regulators of rel/NF-KB transcription factors. Genes Dev 7:2064-2070, 1993
29. Grilli M, Chiu JS, Lenardo MJ: NF-κB and Rel-participants in a multiform transcriptional regulatory system. Int Rev Cytol 143:1-62, 1993
30. Appleby SB, Ristimaki A, Neilson K, Narko K, Hla T: Structure of the human cyclooxygenase-2 gene. Biochem J 302:723-727, 1994
31. Schreiber D, Matthias P, Müller MM, Schaffner W: Rapid detection of octamer binding proteins with "mini-extracts" prepared from a small number of cells. Nucleic Acids Res 17:6419, 1989
32. Hakem R, Le Bouteiller P, Barad M, Trujillo M, Mercier P, Wietzerbin J, Lemonnier FA: IFN-mediated differential regulation of the expression of HLA-B7 and HLA-A3 class I genes. J Immunol 142:297-305, 1989
33. Sokoloski JA, Sartorelli AC, Rosen CA, Narayanan R: Antisense oligonucleotides to the p65 suhunit of NF-κB block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes. Blood 82:625-632, 1993
34. Vane JR, Mitchell JA, Appleton I, Tomlinson A, Bishop-Bailey D, Croxtall J, Willoughby DA: Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci U S A 91:2046-2050, 1994
35. Mehindate K, Al-Daccak R, Dayer J-M, Kennedy BP, Kris C, Borgeat P, Poubelle PE, Mourad W: Superantigen-induced collagenase gene expression in human IFN-γ-treated fibroblast-like synoviocytes involves prostaglandin E2. J Immunol 155:3570-3577, 1995
36. Berenbaum F, Jacques C, Thomas G, Béréziat G, Humbert L, Corvol M, Masliah J: Regulation of secreted phospholipase A2 gene expression by interleukin-1 beta (IL-1β) and insulin-like growth factor-1 (IGF-1): transcriptional and post-transcriptional mechanisms (abstract). Arthritis Rheum 38 (suppl 9):S189, 1995
37. Rïstimaki A, Garfinkel S, Wessendorf J, Maciag T, Hla T: Induction of cyclooxygenase-2 by interleukin-1 alpha: evidence for post-transcriptional regulation. J Biol Chem 269:11769-11775, 1994
38. Morisset S, Lora M, Leduc R, de Brum-Fernandes AJ: Regulation of the expression of cyclooxygenase-1 and cyclooxygenase-2 in bovine chondroblasts in culture (abstract). Arthritis Rheum 38 (suppl 9):S389, 1995
39. De Brum-Fernandes AJ, Laporte S, Heroux M, Lora M, Patry C, Menard HA, Dumais R, Leduc R: Expression of prostaglandin endoperoxide synthase-1 and prostaglandin endoperoxide synthase-2 in human osteoblasts. Biochem Biophys Res Commun 198:955-960, 1994
40. Smith WL: Prostanoid biosynthesis and mechanisms of action. Am J Physiol 263:F181-F191, 1992
41. Tsai C, Diaz LA Jr, Singer NG, Li LL, Kirsch AH, Mitra R, Nickoloff BJ, Crofford LJ, Fox DA: Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes. Arthritis Rheum 39:125-136, 1996
42. Fujisawa K, Aono H, Hasunuma T, Yamamoto K, Mita S, Nishioka K: Activation of transcription factor NF-κB in human synovial cells in response to tumor necrosis factor α. Arthritis Rheum 39:197-203, 1996
43. Okamoto H, Yamamura M, Kashihara N, Harada S, Morita Y, Takehara C, Ota Z: Constitutive activation of NF-κB in rheumatoid synovium (abstract). Arthritis Rheum 38 (suppl 9):S353, 1995
44. Marok R, Winyard PG, Coumbe A, Kus ML, Gaffney K, Blades S, Mapp PI, Morris CJ, Blake DR, Kaltschmidt C, Baeuerle PA: Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissues. Arthritis Rheum 39:583-591, 1996
45. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of I κB synthesis. Science 270:286-290, 1995
46. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr: Role of transcriptional activation of IκBa in mediation of immunosuppression by glucocorticoids. Science 270:283-286, 1995
47. Guesdon F, Waller RJ, Saklatvala J: Specific activation of β-casein kinase by the inflammatory cytokines interleukin 1 and tumour necrosis factor. Biochem J 304:761-768, 1994
48. Inoue H, Yokoyama C, Hara S, Tone Y, Tanabe T: Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J Biol Chem 270:24965-24971, 1995
49. Inoue H, Nanayama T, Hara S, Yokoyama C, Tanabe T: The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett 350:51-54, 1994
50. Shaw G, Kamen R: A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 29:659-667, 1986