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Volumn 277, Issue 17, 1997, Pages 1380-1386

Vitamin E supplementation and in vivo immune response in healthy elderly subjects: A randomized controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; AUTOANTIBODY; HEPATITIS B ANTIBODY; TETANUS TOXOID;

EID: 0030906015     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.277.17.1380     Document Type: Article
Times cited : (514)

References (46)
  • 1
    • 0345106671 scopus 로고
    • Immunological aspects of aging: An overview
    • Schimke RT, ed. Bethesda, Md: US Dept of Agriculture, National Institutes of Health
    • Siskind GW. Immunological aspects of aging: an overview. In: Schimke RT, ed. Biological Mechanism in Aging. Bethesda, Md: US Dept of Agriculture, National Institutes of Health; 1980:455-467.
    • (1980) Biological Mechanism in Aging , pp. 455-467
    • Siskind, G.W.1
  • 2
    • 0024560017 scopus 로고
    • Cutaneous-delayed hypersensitivity in nursing home and geriatric clinic patients: Implications for the tuberculin test
    • Rodysill KJ, Hansen L, O'Leary JJ. Cutaneous-delayed hypersensitivity in nursing home and geriatric clinic patients: implications for the tuberculin test. J Am Geriatr Soc. 1989;37:435-443.
    • (1989) J Am Geriatr Soc. , vol.37 , pp. 435-443
    • Rodysill, K.J.1    Hansen, L.2    O'Leary, J.J.3
  • 5
    • 0021073764 scopus 로고
    • The relationship between cutaneous cellular immune responsiveness and mortality in a nursing home population
    • Cohn JR, Hohl CA, Buckley CE. The relationship between cutaneous cellular immune responsiveness and mortality in a nursing home population. J Am Geriatr Soc. 1983;31:808-809.
    • (1983) J Am Geriatr Soc. , vol.31 , pp. 808-809
    • Cohn, J.R.1    Hohl, C.A.2    Buckley, C.E.3
  • 6
    • 0024380962 scopus 로고
    • Estimating mortality risk in preoperative patients using immunologic, nutritional, and acute-phase response variables
    • Christou NV, Tellado-Rodriguez J, Chartrand L, et al. Estimating mortality risk in preoperative patients using immunologic, nutritional, and acute-phase response variables. Ann Surg. 1989;210:69-77.
    • (1989) Ann Surg. , vol.210 , pp. 69-77
    • Christou, N.V.1    Tellado-Rodriguez, J.2    Chartrand, L.3
  • 7
    • 0029052102 scopus 로고
    • Patterns of age-related immunologic changes
    • Makinodan T. Patterns of age-related immunologic changes. Nutr Rev. 1995;53:S27-S31.
    • (1995) Nutr Rev. , vol.53
    • Makinodan, T.1
  • 8
    • 0018073898 scopus 로고
    • Factors influencing the secondary Ab response to flagellin in man
    • Whittingham S, Buckley JD, MacKay IR. Factors influencing the secondary Ab response to flagellin in man. Clin Exp Immunol. 1978;34:170-178.
    • (1978) Clin Exp Immunol. , vol.34 , pp. 170-178
    • Whittingham, S.1    Buckley, J.D.2    MacKay, I.R.3
  • 9
    • 0027363266 scopus 로고
    • Specific humoral immunity in the elderly: In vivo and in vitro response to vaccination
    • Burns EA, Lum LG, L'Hommedieu G, Goodwin JS. Specific humoral immunity in the elderly: in vivo and in vitro response to vaccination. J Gerontol. 1993;48:B231-B236.
    • (1993) J Gerontol. , vol.48
    • Burns, E.A.1    Lum, L.G.2    L'Hommedieu, G.3    Goodwin, J.S.4
  • 10
    • 0021709175 scopus 로고
    • Influenza and aging: Age-related changes and the effect of thymosin on the Ab response to influenza vaccine
    • Ershler WB, Moore AL, Socinski MA. Influenza and aging: age-related changes and the effect of thymosin on the Ab response to influenza vaccine. J Clin Immunol. 1985;4:445-454.
    • (1985) J Clin Immunol. , vol.4 , pp. 445-454
    • Ershler, W.B.1    Moore, A.L.2    Socinski, M.A.3
  • 11
    • 0018967672 scopus 로고
    • Age-related decline in the in vitro and in vivo synthesis of anti-TT antibody in humans
    • Kishimoto S, Tomino S, Mitsuya H, Fujiwara H. Age-related decline in the in vitro and in vivo synthesis of anti-TT antibody in humans. J Immunol. 1980;1980:2347-2352.
    • (1980) J Immunol. , vol.1980 , pp. 2347-2352
    • Kishimoto, S.1    Tomino, S.2    Mitsuya, H.3    Fujiwara, H.4
  • 12
    • 0016852047 scopus 로고
    • Influenza vaccination and mortality from bronchopneumonia in the elderly
    • Howells CHL, Vesselinova-Jenkins CK, Evans AD, James J. Influenza vaccination and mortality from bronchopneumonia in the elderly. Lancet. 1975; 1:381-383.
    • (1975) Lancet , vol.1 , pp. 381-383
    • Howells, C.H.L.1    Vesselinova-Jenkins, C.K.2    Evans, A.D.3    James, J.4
  • 13
    • 0021928825 scopus 로고
    • Specific immunoglobulin-class antibody responses in the elderly before and after 14-valent pneumococcal vaccine
    • Ruben FL, Uhrin M. Specific immunoglobulin-class antibody responses in the elderly before and after 14-valent pneumococcal vaccine. J Infect Dis. 1985;151:845-848.
    • (1985) J Infect Dis. , vol.151 , pp. 845-848
    • Ruben, F.L.1    Uhrin, M.2
  • 14
    • 0018762762 scopus 로고
    • IgE antibody formation and aging, I: Age-related changes in IgE antibody formation and avidity for the DNP-determinant in mice
    • Fujiwara M, Kishimoto S. IgE antibody formation and aging, I: age-related changes in IgE antibody formation and avidity for the DNP-determinant in mice. J Immunol. 1979;123:263-268.
    • (1979) J Immunol. , vol.123 , pp. 263-268
    • Fujiwara, M.1    Kishimoto, S.2
  • 15
    • 0014404849 scopus 로고
    • Reciprocal change with age in antibody to extrinsic and intrinsic antigens
    • Rowley MJ, Buchanan H, Mackay IR. Reciprocal change with age in antibody to extrinsic and intrinsic antigens. Lancet. 1968;2:24-26.
    • (1968) Lancet , vol.2 , pp. 24-26
    • Rowley, M.J.1    Buchanan, H.2    Mackay, I.R.3
  • 17
    • 0001852713 scopus 로고
    • Age-related immunosuppression: Putative role of prostaglandins
    • Backman RS, Honn XV, Ramwell P, eds. New York, NY: Alan R. Liss
    • Bartocci A, Maggi FM, Welker RD, Veronese F. Age-related immunosuppression: putative role of prostaglandins. In: Backman RS, Honn XV, Ramwell P, eds. Prostaglandins and Cancer. New York, NY: Alan R. Liss; 1982:725-730.
    • (1982) Prostaglandins and Cancer , pp. 725-730
    • Bartocci, A.1    Maggi, F.M.2    Welker, R.D.3    Veronese, F.4
  • 18
    • 0027989633 scopus 로고
    • Age differences in eicosanoid production of mouse splenocytes: Effects on mitogen-induced T-cell proliferation
    • Hayek MG, Meydani SN, Meydani M, Blumberg JB. Age differences in eicosanoid production of mouse splenocytes: effects on mitogen-induced T-cell proliferation. J Gerontol. 1994;49:B197-B207.
    • (1994) J Gerontol. , vol.49
    • Hayek, M.G.1    Meydani, S.N.2    Meydani, M.3    Blumberg, J.B.4
  • 19
    • 0007858125 scopus 로고    scopus 로고
    • Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E
    • Beharka AA, Wu D, Han S-N, Meydani SN. Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E. Mech Ageing Dev. 1997;94:157-165.
    • (1997) Mech Ageing Dev. , vol.94 , pp. 157-165
    • Beharka, A.A.1    Wu, D.2    Han, S.-N.3    Meydani, S.N.4
  • 20
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase (Cox)-2 reverses inflammation and expression of Cox 2 and interleukin 6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory SA. Selective inhibition of cyclooxygenase (Cox)-2 reverses inflammation and expression of Cox 2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest. 1996;97: 2672-2679.
    • (1996) J Clin Invest. , vol.97 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.A.6
  • 21
    • 0019794075 scopus 로고
    • Prostaglandins and host defense in cancer
    • Goodwin JS. Prostaglandins and host defense in cancer. Med Clin North Am. 1981;65:829-844.
    • (1981) Med Clin North Am. , vol.65 , pp. 829-844
    • Goodwin, J.S.1
  • 22
    • 0029117472 scopus 로고
    • Expression of cyclooxygenase-1 and -2 in human colorectal cancer
    • Sano H, Kawahito Y, Wilder RL, et al. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res. 1995;55:3785-3789.
    • (1995) Cancer Res. , vol.55 , pp. 3785-3789
    • Sano, H.1    Kawahito, Y.2    Wilder, R.L.3
  • 24
    • 0026487750 scopus 로고
    • Effect of vitamin and trace-element supplementation on immune responses and infectious disease in elderly subjects
    • Chandra RK. Effect of vitamin and trace-element supplementation on immune responses and infectious disease in elderly subjects. Lancet. 1992; 340:1124-1127.
    • (1992) Lancet , vol.340 , pp. 1124-1127
    • Chandra, R.K.1
  • 25
    • 0028018199 scopus 로고
    • Daily micronutrient supplements enhance delayed-hypersensitivity skin test responses in older people
    • Bogden JD, Bendich A, Kemp FW, et al. Daily micronutrient supplements enhance delayed-hypersensitivity skin test responses in older people. Am J Clin Nutr. 1994;60:437-447.
    • (1994) Am J Clin Nutr. , vol.60 , pp. 437-447
    • Bogden, J.D.1    Bendich, A.2    Kemp, F.W.3
  • 27
    • 0027946392 scopus 로고
    • Assessment of the safety of high-dose, short-term supplementation with vitamin E in healthy older adults
    • Meydani SN, Meydani M, Rall L, Morrow F, Blumberg JB. Assessment of the safety of high-dose, short-term supplementation with vitamin E in healthy older adults. Am J Clin Nutr. 1994;60: 704-709.
    • (1994) Am J Clin Nutr. , vol.60 , pp. 704-709
    • Meydani, S.N.1    Meydani, M.2    Rall, L.3    Morrow, F.4    Blumberg, J.B.5
  • 28
    • 0027323508 scopus 로고
    • Immunologic effects of National Cholesterol Education Panel (NCEP) Step-2 diets with and without fish-derived n-3 fatty acid enrichment
    • Meydani SN, Lichtenstein AH, Cornwall S, et al. Immunologic effects of National Cholesterol Education Panel (NCEP) Step-2 diets with and without fish-derived n-3 fatty acid enrichment. J Clin Invest. 1993;92:105-113.
    • (1993) J Clin Invest. , vol.92 , pp. 105-113
    • Meydani, S.N.1    Lichtenstein, A.H.2    Cornwall, S.3
  • 29
    • 0028805501 scopus 로고
    • Serum, breast milk, and infant antibody after maternal immunization with pneumococcal vaccine
    • Shahid NS, Steinhof MC, Hoque SS, Begum T, Thompson C, Siber G. Serum, breast milk, and infant antibody after maternal immunization with pneumococcal vaccine. Lancet. 1995;346:1252-1257.
    • (1995) Lancet , vol.346 , pp. 1252-1257
    • Shahid, N.S.1    Steinhof, M.C.2    Hoque, S.S.3    Begum, T.4    Thompson, C.5    Siber, G.6
  • 30
    • 0025204745 scopus 로고
    • Impaired antibody response to Haemophilus influenzae type B polysaccharide and low IgG2 and IgG4 in Apache children
    • Siber GR, Santosham M, Reid GR, et al. Impaired antibody response to Haemophilus influenzae type B polysaccharide and low IgG2 and IgG4 in Apache children. N Engl J Med. 1990;323:1387-1392.
    • (1990) N Engl J Med. , vol.323 , pp. 1387-1392
    • Siber, G.R.1    Santosham, M.2    Reid, G.R.3
  • 31
    • 0022468296 scopus 로고
    • A rapid ELISA for measurement of antibodies to nucleic acid antigens using YV-related polystyrene microplates
    • Zouali M, Stollar BD. A rapid ELISA for measurement of antibodies to nucleic acid antigens using YV-related polystyrene microplates. J Immunol Methods. 1986;90:105-110.
    • (1986) J Immunol Methods , vol.90 , pp. 105-110
    • Zouali, M.1    Stollar, B.D.2
  • 32
    • 0018677726 scopus 로고
    • Simultaneous determination of alpha-tocopherol and retinol in plasma or red cells by high-pressure liquid chromatography
    • Bieri JG, Tolliver TJ, Catignani GL. Simultaneous determination of alpha-tocopherol and retinol in plasma or red cells by high-pressure liquid chromatography. Am J Clin Nutr. 1979;32:2143-2149.
    • (1979) Am J Clin Nutr. , vol.32 , pp. 2143-2149
    • Bieri, J.G.1    Tolliver, T.J.2    Catignani, G.L.3
  • 33
    • 0025780249 scopus 로고
    • Effect of long-term fish oil supplementation on vitamin E status and lipid peroxidation in women
    • Meydani M, Natiello F, Goldin B, et al. Effect of long-term fish oil supplementation on vitamin E status and lipid peroxidation in women. J Nutr. 1991;121:484-491.
    • (1991) J Nutr. , vol.121 , pp. 484-491
    • Meydani, M.1    Natiello, F.2    Goldin, B.3
  • 34
    • 1842367597 scopus 로고
    • [database online] Grand Forks, ND: US Dept of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center
    • GRAND [database online]. Grand Forks, ND: US Dept of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center; 1990.
    • (1990) GRAND
  • 35
    • 0026093358 scopus 로고
    • Disparate effects of interferon-gamma and tumor necrosis factor-alpha on early neutrophil respiratory burst and fungicidal responses to Candida albicans hyphae in vitro
    • Diamond RD, Lyman CA, Wysong DR. Disparate effects of interferon-gamma and tumor necrosis factor-alpha on early neutrophil respiratory burst and fungicidal responses to Candida albicans hyphae in vitro. J Clin Invest. 1991;87:711-720.
    • (1991) J Clin Invest. , vol.87 , pp. 711-720
    • Diamond, R.D.1    Lyman, C.A.2    Wysong, D.R.3
  • 36
    • 0025004702 scopus 로고
    • Effect of vitamin E supplementation on immune responsiveness of healthy elderly subjects
    • Meydani SN, Barklund PM, Liu S, et al. Effect of vitamin E supplementation on immune responsiveness of healthy elderly subjects. Am J Clin Nutr. 1990;52:557-563.
    • (1990) Am J Clin Nutr. , vol.52 , pp. 557-563
    • Meydani, S.N.1    Barklund, P.M.2    Liu, S.3
  • 37
    • 0000692480 scopus 로고
    • Immunological nutritional status among the elderly
    • Chandra RK, ed. Elmsford, NY: Pergamon Press Inc
    • Chavance M, Brubacher G, Herbert B, et al. Immunological nutritional status among the elderly. In: Chandra RK, ed. Nutritional Immunity and Illness in the Elderly. Elmsford, NY: Pergamon Press Inc; 1985:137-142.
    • (1985) Nutritional Immunity and Illness in the Elderly , pp. 137-142
    • Chavance, M.1    Brubacher, G.2    Herbert, B.3
  • 39
    • 0010387739 scopus 로고
    • Effect of vitamin E on disease resistance and immune response
    • de Duve C, Hayaishi O, eds. New York, NY: Elsevier Science Inc
    • Tengerdy RP, Heinzerling RH, Mathias MM. Effect of vitamin E on disease resistance and immune response. In: de Duve C, Hayaishi O, eds. Tocopherol, Oxygen, and Biomembranes. New York, NY: Elsevier Science Inc; 1978:191-200.
    • (1978) Tocopherol, Oxygen, and Biomembranes , pp. 191-200
    • Tengerdy, R.P.1    Heinzerling, R.H.2    Mathias, M.M.3
  • 41
    • 0017063846 scopus 로고
    • Effect of supplemental dietary vitamin E on the serologic response of swine to an Escherichia coli bacteria
    • Ellis RP, Vorhies MW. Effect of supplemental dietary vitamin E on the serologic response of swine to an Escherichia coli bacteria. J Am Vet Med Assoc. 1986;168:231-232.
    • (1986) J Am Vet Med Assoc. , vol.168 , pp. 231-232
    • Ellis, R.P.1    Vorhies, M.W.2
  • 42
    • 0016270480 scopus 로고
    • Vitamin E protects mice against Diplococcus pneumonia type I infection
    • Heinzerling RH, Tengerdy RP, Wick LL, Lueker DC. Vitamin E protects mice against Diplococcus pneumonia type I infection. Infect Immun. 1974;10:1292-1295.
    • (1974) Infect Immun. , vol.10 , pp. 1292-1295
    • Heinzerling, R.H.1    Tengerdy, R.P.2    Wick, L.L.3    Lueker, D.C.4
  • 43
    • 85046173047 scopus 로고    scopus 로고
    • Vitamin E supplementation decreases lung viral titer in mice infected with influenza
    • In press
    • Hayek MG, Taylor SF, Bender BS, et al. Vitamin E supplementation decreases lung viral titer in mice infected with influenza. J Infect Dis. In press.
    • J Infect Dis.
    • Hayek, M.G.1    Taylor, S.F.2    Bender, B.S.3
  • 44
    • 0028097387 scopus 로고
    • Nutritional status and immune responses in mice with murine AIDS are normalized by vitamin E supplementation
    • Wang Y, Hwang DS, Licing B, Watson RR. Nutritional status and immune responses in mice with murine AIDS are normalized by vitamin E supplementation. J Nutr. 1994;124:2024-2032.
    • (1994) J Nutr. , vol.124 , pp. 2024-2032
    • Wang, Y.1    Hwang, D.S.2    Licing, B.3    Watson, R.R.4
  • 46
    • 0020068274 scopus 로고
    • Swine dysentery: The influence of dietary vitamin E and selenium on the clinical and pathological effect of Treponema hyodysenteriae infection in pigs
    • Teige J, Tollersrud S, Lund A, Larsen HJ. Swine dysentery: the influence of dietary vitamin E and selenium on the clinical and pathological effect of Treponema hyodysenteriae infection in pigs. Res Vet Sci. 1982;32:95-160.
    • (1982) Res Vet Sci. , vol.32 , pp. 95-160
    • Teige, J.1    Tollersrud, S.2    Lund, A.3    Larsen, H.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.