Lipopolysaccharide-induced lethality and cytokine production in aged mice

Infection and Immunity

Volumn 64, Issue 3, 1996, Pages 769-774

  Tateda, Kazuhiro ^a   Matsumoto, Tetsuya ^a   Miyazaki, Shuichi ^a   Yamaguchi, Keizo ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DRUG INDUCED DISEASE; IMMUNE SYSTEM; IMMUNOGLOBULIN PRODUCTION; IMMUNOREGULATION; LETHALITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; T LYMPHOCYTE;

EID: 0030038450     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.3.769-774.1996     Document Type: Article

References (51)

1. Alexander, H. R., G. M. Doherty, C. M. Buresh, D. J. Venzon, and J. A. Norton. 1991. A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice J. Exp. Med. 173:1029-1032.
2. Bertini, R., M. Blanchi, and P. Ghezzi. 1988 Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J. Exp. Med. 167:1708-1712
3. Besedovsky, H. O., A. D. Rey, I. Klusman, H. Furukawa, G. M. Arditi, and A. Kabiersch. 1991. Cytokines as modulators of the hypothalamus-pituitary-adrenal axis. J. Steroid Biochein. Mol. Biol. 40:613-618.
4. Besedovsky, H. O., A. D. Rey, E. Sorkin, and C. A. Dinarello. 1986. Immunoregulatory feedback between interieukin-1 and glucocorticoid hormones Science 233:652-654.
5. Beutler, B., N. Krochin, I. W. Milsark, C. Luedke, and A. Cerami. 1986. Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. Science 232:977-980
6. Beutler, B., J. W. Milsark, and A. C. Cerami. 1985. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229:809-871.
7. Black, P. H. 1994. Immune system-central nervous system interactions: effect and immunomodulatory consequences of immune system mediators on the brain. Antimicrob. Agents Chemother. 38:7-12.
8. Bogdan, C., J. Paik, Y. Vodovotz, and C. Nathan. 1992. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10 J. Biol Chem. 207:23301-23308.
9. Bone, R. C. 1991. The pathogenesis of sepsis. Ann Intern Med 115:457-469.
10. Bradley, S. F., A. Vibhagool, S. L. Kunkel, and C. A. Kauffman. 1989. Monokine secretion in aging and protein malnutrition. J. Leukocyte Biol. 45: 510-514.
11. Bruley-Rosset, M., and I. Vergnon. 1984. Interleukin-1 synthesis and activity in aged mice. Mech. Ageing Dev. 24:247-264.
12. Chen, Y., and S. F. Bradley. 1993. Aging and eliciting agents: effect on murine peritoneal macrophage monokine bioactivity Exp. Gerontol 28: 145-159
13. Chopra, R. K., N. J. Holbrook, D. C. Powers, M. T. McCoy, W. H. Adler, and J. E. Nagel. 1989. Interleukin 2, interleukin 2 receptor, and interferon-gamma synthesis and mRNA expression in phorbol myristate acetate and calcium ionophore A23187-stimulated T cells from elderly humans. Clin. Immunol. Immunopathol. 53:297-308.
14. Daynes, R. A., B. A. Araneo, W. B. Ershler, C. Maloney, G. Z. Li, and S. Y. Ryu. 1993. Altered regulation of IL-6 production with normal aging. J. Immunol. 150:5219-5230.
15. Doherty, G. M., J. R. Lange, H. N. Langstein, H. R. Alexander, C. M. Buresh, and J. A. Norton. 1992. Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha. J. Immunol. 149: 1666-1670
16. Effros, R. B., K. Svoboda, and R. L. Walford. 1991. Influence of age and caloric restriction on macrophage IL-6 and TNF production. Lymphokine Cytokine Res. 10:347-351.
17. + T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44. CD45RB. 3G11. and MEL-14 expression J Immunol. 151:575-587.
18. Ershler, W. B., W. H. Sun, N. Binkley, S. Gravenstein, M. J. Volk, G. Kamoske, R. G. Klopp, E. B. Roecker, R. A. Daynes, and R. Weindruch. 1993. Interleukin-6 and aging. blood levels and mononuclear cell production increase with advancing age and in vitro production is modulable by dietary restriction. Lymphokine Cytokine Res. 12:225-230.
19. Fagiolo, U., A. Cossarizza, E. Scala, E. F. Belasio, C. Ortolani, E. Cozzi, D. Monti, C. Franceschi, and R. Paganelli, 1993. Increased cytokine production in mononuclear cells of healthy elderly people. Eur. J. Immunol. 23:2375-2378.
20. Foster, K. D., C. A. Conn, and M. J. Kluger. 1992 Fever, tumor necrosis factor, and interleukin-6 in young, mature, and aged Fischer 344 rats. Am. J. Physiol. 262:R211-R215
21. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Bazil, T. Espevik, B. B. Finlay, and S. D. Wright. 1992. Soluble CD14 participates in the responses of cells to lipopolysaccharide. J. Exp. Med. 176:1665-1671.
22. Gardner, I. D. 1980. The effect of aging on susceptibility to infection. Rev. Infect Dis. 2:801-810.
23. Gerard, C., C. Bruyns, A. Marchant, D. Abramowicz, P. Vandenabeele, A. Delvaux, W. Fiers, M. Goldman, and T. Velu. 1993 Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J. Exp. Med. 177:547-550.
24. Heinzel, F. P. 1990. The role of IFN-gamma in the pathology of experimental endotoxemia. J. Immunol 145:2920-2924.
25. + cells and cell subsets from young and old mice. Cell. Immunol. 154:264-272.
26. + T cells from young and old mice. J. Immunol. 150: 3602-3614.
27. Howard, M., T. Muchamuel, S. Andrade, and S. Menon. 1993. Interleukin 10 protects mice from lethal endotoxemia. J. Exp Med. 177:1205-1208
28. Hyde, S. R., and R. E. McCallum. 1992. Lipopolysaccharide-tumor necrosis factor-glucocorticoid interactions during cecal ligation and puncture-induced sepsis in mature versus senescent mice. Infect. Immun. 60:976-982
29. Inamizu, T., M. P. Chang, and T. Makinodan. 1985 Influence of age on the production and regulation of interleukin-1 in mice. Immunology 55:447-455.
30. Kalimi, M., and S. Gupta. 1982. Physicochemical characterization of rat liver glucocorticoid receptor during development. J. Biol. Chem. 257:13324-13328
31. Kalimi, M., S. Gupta, J. Hubbard, and K. Greene. 1983 Glucocorticoid receptors in adult and senescent rat liver Endocrinology 112:341-347.
32. Karanfilian, R. G., C. R. Spillert, G. W. Machiedo, B. F. Rush, Jr., and E. J. Lazaro. 1983 Effect of age and splenectomy in murine endotoxemia. Adv. Shock Res. 9:125-132.
33. Knudsen, P. J., C. A. Dinarello, and T. B. Strom. 1987. Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin-1 in U937 cells J Immunol. 139:4129-4134.
34. Kunkel, S. L., M. Spengler, M. A. May, R. Spengler, J. Larrick, and D. Remick. 1988. Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression J Biol. Chem. 263:5380-5384.
35. Lehmann, V., M. A. Frendenberg, and C. Galanos. 1987. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J. Exp Med. 165:657-663.
36. Malefyt, R. D. W., J. Abrams, B. Bennett, C. G. Figdor, and J. E. D. Vries. 1991. Interleukin 10 (IL-10) inhibits eytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174: 1209-1220.
37. Meyers, B. R., E. Sherman, M. H. Mendelson, G. Velasquez, E. Srulevitch-Chin, M. Hubbard, and S. Z. Hirschman. 1989. Bloodstream infections in the elderly. Am. J. Med. 86:379-384.
38. + T cells Eur. J. Immunol. 21:273-281.
39. Orme, I. M. 1987 Aging and immunity to tuberculosis, increased susceptibility of old mice reflects a decreased capacity to generate mediator T lymphocytes. J Immunol. 138:4414-4418.
40. Parant, M., C. L. Contel, F. Parant, and L. Chedid. 1991 Influence of endogenous glucocorticoid on endotoxin-induced production of circulating TNF-alpha. Lymphokine Cytokine Res. 10:265-271.
41. Patel, P. J. 1982 Aging and antimicrobial immunity. Lowered efficiency of protective T cells as a contributing factor for the decreased resistance of senescent mice to listeriosis. J Exp. Med. 155:1870-1875
42. Reichlin, S. 1993. Neuroendocrine-immune interactions. N Engl. J. Med 329:1246-1253.
43. Riancho, J. A., M. T. Zarrabeitia, J. A. Amado, J. M. Olmos, and J. G. Macias. 1994. Age-related differences in cytokine secretion. Gerontology 40: 8-12.
44. Saxena, R. K., Q. B. Saxena, and W. H. Adler. 1988. Lectin-induced cytotoxic activity in spleen cells from young and old mice. Age-related changes in types of effector cells. lymphokine production and response. Immunology 64:457-461
45. Setia, U., I. Serventi, and P. Lorenz. 1984. Bacteremia in a long-lerm care facility Arch Intern Med 144:1633-1635.
46. Shumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevitch. 1990. Structure and function of lipopolysaccharide binding protein Science 249:1429-1431.
47. Solana, R., J. L. Villanueva, J. Pena, and M. De la Fuente. 1991. Cell mediated immunity in ageing Comp. Biochem. Physiol. 99A:1-4
48. Spinas, G. A., U. Keller, and M. Brockhaus. 1992. Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxemia J Clin. Invest 90:533-536.
49. Terpenning, M. S., and S. F. Bradley. 1991. Why aging leads to increased susceptibility to infection. Geriatrics 46:77-80.
50. Thoman, M. L., and W. O. Weigle, 1981 Lymphokines and aging: interleukin-2 production and activity in aged animals. J. Immunol. 127:2102-2106
51. Zahl, P. A., S. H. Hutner, and F. S. Cooper. 1943 Age as a factor in susceptibility of mice to the endotoxin of bacillary dysentery. Proc. Soc. Exp. Biol. Med. 54:137-139.