Bezafibrate has an antioxidant effect: Peroxisome proliferator-activated receptor α is associated with Cu2+, Zn2+-superoxide dismutase in the liver

Life Sciences

Volumn 63, Issue 2, 1998, Pages 135-144

  Inoue, Ikuo ^a   Noji, Satoru ^a   Awata, Takuya ^a   Takahashi, Keiichi ^a   Nakajima, Takanori ^a   Sonoda, Masaru ^a   Komoda, Tsugikazu ^a   Katayama, Shigehiro ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Antioxidant; Bezafibrate; Catalase; Cu2+; Peroxisome proliferator activated receptor ; Zn2+ superoxide dismutase

Indexed keywords

BEZAFIBRATE; COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG EFFECT; ENZYME ANALYSIS; GENE EXPRESSION; HYPERLIPIDEMIA; LIVER; MALE; NONHUMAN; RAT; RNA ANALYSIS;

ACYL-COA OXIDASE; ANIMALS; ANTILIPEMIC AGENTS; ANTIOXIDANTS; BEZAFIBRATE; CATALASE; CHOLESTEROL; DIET; DIETARY FATS; FATTY ACIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIVER; MALE; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SOYBEANS; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRANSCRIPTION FACTORS;

EID: 0032486173     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00249-5     Document Type: Article

References (19)

1. 1. I. INOUE, K. TAKAHASHI, S. KATAYAMA, K. NEGISHI and J. ISHII, Metabolism 45 1-6(1996).
2. 2. I. INOUE, S. NOJI, M.-Z. SHEN, K. TAKAHASHI and S. KATAYAMA, Biochem. Biophys. Res. Commum. 237 606-610(1997).
3. 3. I. ISSEMANN and S. GREEN, Nature 347 645-650(1990).
4. 4. C.-E. ERICSSON, A. HAMSTEN, J. NILSSON, L. GRIP, B. SVANE and U. DE FAIRE, Lancet 347 849-853(1996).
5. 5. L.D. METCALFE and A.A. SCHMITZ, Anal. Chem. 33 363-369 (1961).
6. 6. R.J. HAVEL, H.A. EDER and J.H. BRAGDON, J. Clin. Invest. 34 1345-1353(1955).
7. 7. K. YAGI, Biochem. Med. 15 212-216(1976).
8. 8. J.P. VUILLEUMIER, H.E. KELLER and F. HUNZIKER, Int. J. Vit. Nutr. Res. 53 265-272(1983).
9. 9. I. INOUE, K. TAKAHASHI, C. KIKUCHI and S. KATAYAMA, Diabetes Care 18 1101-1106(1996).
10. 10. L. FOLCH, J. Biol. Chem. 226 497-509(1957).
11. 11. J.M. DELABAR, A. NICOLE, L. D'AURIOL, Y. JACOB, M. MEUNIER-ROTIVAL, F. GALIBERT, P.M. SINET and H. JEROME, Eur. J. Biochem. 166 181-187(1987).
12. 12. H.T. YUAN, C.D. BINGLE and F.J. KELLY, Biochim. Biophys. Acta 1305 163-171(1996).
13. 13. P.F. STERCHELE, H. SUN, R.E. PETERSON and P.V. HEUVEL, Arch. Biochem. Biophys. 326 281-289(1996).
14. 14. I. NISHIGAKI, M. HAGIHARA, H. TSUNEKAWA, M. MASEKI and K. YAGI, Biochem. Med. 25 373-378(1981).
15. 15. I. INOUE, K. TAKAHASHI, S. KATAYAMA, S. AKABANE, K. NEGISHI, M. SUZUKI, J. ISHII and S. KAWAZU, Diabetes Res. Clin. Pract. 25 199-205(1994).
16. 16. A. BRANCHI, A. ROVELLINI, D. SOMMARIVA, A.G. GUGLIANDOLO and A. FASOLI, Thromb. Haemostasis 70 241-243(1993).
17. 17. M.R. CESARONE, G. LAURORA, M.T. DESANCTIS, P. POMANTE and G. BELCARO, Minerva Cardioangiologica 40 15-21(1992).
18. 18. C-E. ERICSSON, A. HAMSTEN, J. NILSSON, L. GRIP, B. SVANE and U. DE FAIRE, Lancet 347 849-853(1996).
19. 19. P.R. DEVCHAND, H. KELLER, J.M. PETERS, M. VAZQUEZ, F.J. GONZALEZ, and W. WAHLI, Nature 384 39-43(1996).