-
1
-
-
0020791750
-
Effects of a dietary excess of leucine on the metabolism of tryptophan in the rat: a mechanism for the pellagragenic action of leucine
-
COI: 1:CAS:528:DyaL3sXltVCisL8%3D, PID: 6882730
-
Bender DA. Effects of a dietary excess of leucine on the metabolism of tryptophan in the rat: a mechanism for the pellagragenic action of leucine. Br J Nutr. 1983;50:25–32.
-
(1983)
Br J Nutr
, vol.50
, pp. 25-32
-
-
Bender, D.A.1
-
2
-
-
65349192177
-
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice
-
PID: 19323847
-
Kanai M, Funakoshi H, Takahashi H, Hayakawa T, Mizuno S, Matsumoto K, et al. Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice. Mol Brain. 2009;2:8.
-
(2009)
Mol Brain
, vol.2
-
-
Kanai, M.1
Funakoshi, H.2
Takahashi, H.3
Hayakawa, T.4
Mizuno, S.5
Matsumoto, K.6
-
3
-
-
85026285162
-
Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health
-
PID: 28751584
-
Cervenka I, Agudelo LZ, Ruas JL. Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health. Science. 2017;357:eaaf9794.
-
(2017)
Science
, vol.357
, pp. eaaf9794
-
-
Cervenka, I.1
Agudelo, L.Z.2
Ruas, J.L.3
-
4
-
-
0021186590
-
Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid
-
COI: 1:CAS:528:DyaL2cXlsVGntLg%3D, PID: 6237279
-
Foster AC, Vezzani A, French ED, Schwarcz R. Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid. Neurosci Lett. 1984;48:273–8.
-
(1984)
Neurosci Lett
, vol.48
, pp. 273-278
-
-
Foster, A.C.1
Vezzani, A.2
French, E.D.3
Schwarcz, R.4
-
5
-
-
0024564076
-
A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists
-
COI: 1:CAS:528:DyaL1MXhs1Klur4%3D, PID: 2538568
-
Kessler M, Terramani T, Lynch G, Baudry M. A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists. J Neurochem. 1989;52:1319–28.
-
(1989)
J Neurochem
, vol.52
, pp. 1319-1328
-
-
Kessler, M.1
Terramani, T.2
Lynch, G.3
Baudry, M.4
-
6
-
-
0034949090
-
Presynaptic kynurenate-sensitive receptors inhibit glutamate release
-
COI: 1:STN:280:DC%2BD3Mzmt1WqsA%3D%3D, PID: 11422455
-
Carpenedo R, Pittaluga A, Cozzi A, Attucci S, Galli A, Raiteri M, et al. Presynaptic kynurenate-sensitive receptors inhibit glutamate release. Eur J Neurosci. 2001;13:2141–7.
-
(2001)
Eur J Neurosci
, vol.13
, pp. 2141-2147
-
-
Carpenedo, R.1
Pittaluga, A.2
Cozzi, A.3
Attucci, S.4
Galli, A.5
Raiteri, M.6
-
7
-
-
0035478066
-
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications
-
COI: 1:CAS:528:DC%2BD3MXnsFCksrc%3D, PID: 11567036
-
Hilmas C, Pereira EF, Alkondon M, Rassoulpour A, Schwarcz R, Albuquerque EX. The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. J Neurosci. 2001;21:7463–73.
-
(2001)
J Neurosci
, vol.21
, pp. 7463-7473
-
-
Hilmas, C.1
Pereira, E.F.2
Alkondon, M.3
Rassoulpour, A.4
Schwarcz, R.5
Albuquerque, E.X.6
-
8
-
-
33746823331
-
Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35
-
COI: 1:CAS:528:DC%2BD28XnsVOmsbo%3D, PID: 16754668
-
Wang J, Simonavicius N, Wu X, Swaminath G, Reagan J, Tian H, et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006;281:22021–8.
-
(2006)
J Biol Chem
, vol.281
, pp. 22021-22028
-
-
Wang, J.1
Simonavicius, N.2
Wu, X.3
Swaminath, G.4
Reagan, J.5
Tian, H.6
-
9
-
-
37349129072
-
Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons
-
COI: 1:CAS:528:DC%2BD1cXhsF2nsA%3D%3D, PID: 17940199
-
Guo J, Williams DJ, Puhl HL 3rd, Ikeda SR. Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons. J Pharmacol Exp Ther. 2008;324:342–51.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 342-351
-
-
Guo, J.1
Williams, D.J.2
Puhl, H.L.3
Ikeda, S.R.4
-
10
-
-
85040523738
-
Kynurenic acid: the Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions
-
PID: 29379504
-
Wirthgen E, Hoeflich A, Rebl A, Gunther J. Kynurenic acid: the Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions. Front Immunol. 2017;8:1957.
-
(2017)
Front Immunol
, vol.8
, pp. 1957
-
-
Wirthgen, E.1
Hoeflich, A.2
Rebl, A.3
Gunther, J.4
-
11
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
COI: 1:CAS:528:DC%2BC3MXht1ylt7nI, PID: 21976023
-
Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature. 2011;478:197–203.
-
(2011)
Nature
, vol.478
, pp. 197-203
-
-
Opitz, C.A.1
Litzenburger, U.M.2
Sahm, F.3
Ott, M.4
Tritschler, I.5
Trump, S.6
-
12
-
-
0019440926
-
Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS
-
COI: 1:CAS:528:DyaL3MXlsVChs7Y%3D, PID: 6268428
-
Stone TW, Perkins MN. Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS. Eur J Pharmacol. 1981;72:411–2.
-
(1981)
Eur J Pharmacol
, vol.72
, pp. 411-412
-
-
Stone, T.W.1
Perkins, M.N.2
-
13
-
-
84859582577
-
Quinolinic acid, the inescapable neurotoxin
-
COI: 1:CAS:528:DC%2BC38XmsVejs7k%3D, PID: 22248144
-
Guillemin GJ. Quinolinic acid, the inescapable neurotoxin. FEBS J. 2012;279:1356–65.
-
(2012)
FEBS J
, vol.279
, pp. 1356-1365
-
-
Guillemin, G.J.1
-
14
-
-
0037337196
-
Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes
-
PID: 12555204
-
Guillemin GJ, Croitoru-Lamoury J, Dormont D, Armati PJ, Brew BJ. Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes. Glia. 2003;41:371–81.
-
(2003)
Glia
, vol.41
, pp. 371-381
-
-
Guillemin, G.J.1
Croitoru-Lamoury, J.2
Dormont, D.3
Armati, P.J.4
Brew, B.J.5
-
15
-
-
84868094724
-
Activation of microglial N-methyl-d-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain
-
COI: 1:CAS:528:DC%2BC38Xhs1ShsbrL, PID: 23109148
-
Kaindl AM, Degos V, Peineau S, Gouadon E, Chhor V, Loron G, et al. Activation of microglial N-methyl-d-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain. Ann Neurol. 2012;72:536–49.
-
(2012)
Ann Neurol
, vol.72
, pp. 536-549
-
-
Kaindl, A.M.1
Degos, V.2
Peineau, S.3
Gouadon, E.4
Chhor, V.5
Loron, G.6
-
16
-
-
85046786158
-
Kynurenine pathway metabolic balance influences microglia activity: targeting kynurenine monooxygenase to dampen neuroinflammation
-
COI: 1:CAS:528:DC%2BC1cXptVagtrw%3D, PID: 29734055
-
Garrison AM, Parrott JM, Tunon A, Delgado J, Redus L, O’Connor JC. Kynurenine pathway metabolic balance influences microglia activity: targeting kynurenine monooxygenase to dampen neuroinflammation. Psychoneuroendocrinology. 2018;94:1–10.
-
(2018)
Psychoneuroendocrinology
, vol.94
, pp. 1-10
-
-
Garrison, A.M.1
Parrott, J.M.2
Tunon, A.3
Delgado, J.4
Redus, L.5
O’Connor, J.C.6
-
17
-
-
0026076136
-
Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism
-
COI: 1:CAS:528:DyaK3MXktVGltLY%3D, PID: 1827495
-
Fukui S, Schwarcz R, Rapoport SI, Takada Y, Smith QR. Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism. J Neurochem. 1991;56:2007–17.
-
(1991)
J Neurochem
, vol.56
, pp. 2007-2017
-
-
Fukui, S.1
Schwarcz, R.2
Rapoport, S.I.3
Takada, Y.4
Smith, Q.R.5
-
18
-
-
0036064548
-
Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain
-
COI: 1:CAS:528:DC%2BD38XlslKmsbc%3D, PID: 12124427
-
Kita T, Morrison PF, Heyes MP, Markey SP. Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain. J Neurochem. 2002;82:258–68.
-
(2002)
J Neurochem
, vol.82
, pp. 258-268
-
-
Kita, T.1
Morrison, P.F.2
Heyes, M.P.3
Markey, S.P.4
-
19
-
-
0031036955
-
Quantification of local de novo synthesis versus blood contributions to quinolinic acid concentrations in brain and systemic tissues
-
COI: 1:CAS:528:DyaK2sXhs1Sjsw%3D%3D, PID: 8978736
-
Heyes MP, Morrison PF. Quantification of local de novo synthesis versus blood contributions to quinolinic acid concentrations in brain and systemic tissues. J Neurochem. 1997;68:280–8.
-
(1997)
J Neurochem
, vol.68
, pp. 280-288
-
-
Heyes, M.P.1
Morrison, P.F.2
-
20
-
-
85031418924
-
Impact of Inflammation on the blood-neural barrier and blood-nerve interface: from review to therapeutic preview
-
PID: 29132542
-
Skaper SD. Impact of Inflammation on the blood-neural barrier and blood-nerve interface: from review to therapeutic preview. Int Rev Neurobiol. 2017;137:29–45.
-
(2017)
Int Rev Neurobiol
, vol.137
, pp. 29-45
-
-
Skaper, S.D.1
-
21
-
-
85028059681
-
The blood-brain barrier in psychosis
-
PID: 28781208
-
Pollak TA, Drndarski S, Stone JM, David AS, McGuire P, Abbott NJ. The blood-brain barrier in psychosis. Lancet Psychiatry. 2018;5:79–92.
-
(2018)
Lancet Psychiatry
, vol.5
, pp. 79-92
-
-
Pollak, T.A.1
Drndarski, S.2
Stone, J.M.3
David, A.S.4
McGuire, P.5
Abbott, N.J.6
-
22
-
-
0026655828
-
Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients
-
COI: 1:STN:280:DyaK38zovVCjug%3D%3D, PID: 1387655
-
Heyes MP, Brew BJ, Saito K, Quearry BJ, Price RW, Lee K, et al. Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients. J Neuroimmunol. 1992;40:71–80.
-
(1992)
J Neuroimmunol
, vol.40
, pp. 71-80
-
-
Heyes, M.P.1
Brew, B.J.2
Saito, K.3
Quearry, B.J.4
Price, R.W.5
Lee, K.6
-
23
-
-
77950022119
-
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression
-
COI: 1:CAS:528:DC%2BC3cXjslWitr8%3D, PID: 19918244
-
Raison CL, Dantzer R, Kelley KW, Lawson MA, Woolwine BJ, Vogt G, et al. CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry. 2010;15:393–403.
-
(2010)
Mol Psychiatry
, vol.15
, pp. 393-403
-
-
Raison, C.L.1
Dantzer, R.2
Kelley, K.W.3
Lawson, M.A.4
Woolwine, B.J.5
Vogt, G.6
-
24
-
-
0043076307
-
Induction of pulmonary indoleamine 2,3-dioxygenase by interferon
-
COI: 1:CAS:528:DyaL3MXhtF2gs7w%3D, PID: 6165986
-
Yoshida R, Imanishi J, Oku T, Kishida T, Hayaishi O. Induction of pulmonary indoleamine 2,3-dioxygenase by interferon. Proc Natl Acad Sci USA. 1981;78:129–32.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 129-132
-
-
Yoshida, R.1
Imanishi, J.2
Oku, T.3
Kishida, T.4
Hayaishi, O.5
-
25
-
-
46349106773
-
Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma?
-
COI: 1:CAS:528:DC%2BD1cXotlCnsr8%3D, PID: 18584961
-
Connor TJ, Starr N, O’Sullivan JB, Harkin A. Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma? Neurosci Lett. 2008;441:29–34.
-
(2008)
Neurosci Lett
, vol.441
, pp. 29-34
-
-
Connor, T.J.1
Starr, N.2
O’Sullivan, J.B.3
Harkin, A.4
-
26
-
-
84857046187
-
Interleukin-1beta: a new regulator of the kynurenine pathway affecting human hippocampal neurogenesis
-
COI: 1:CAS:528:DC%2BC38XitlKhsrs%3D, PID: 22071871
-
Zunszain PA, Anacker C, Cattaneo A, Choudhury S, Musaelyan K, Myint AM, et al. Interleukin-1beta: a new regulator of the kynurenine pathway affecting human hippocampal neurogenesis. Neuropsychopharmacology. 2012;37:939–49.
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 939-949
-
-
Zunszain, P.A.1
Anacker, C.2
Cattaneo, A.3
Choudhury, S.4
Musaelyan, K.5
Myint, A.M.6
-
27
-
-
0033949638
-
Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells
-
COI: 1:CAS:528:DC%2BD3cXjvVSkt7o%3D, PID: 10843733
-
Babcock TA, Carlin JM. Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells. Cytokine. 2000;12:588–94.
-
(2000)
Cytokine
, vol.12
, pp. 588-594
-
-
Babcock, T.A.1
Carlin, J.M.2
-
28
-
-
65249156122
-
Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin
-
PID: 19339614
-
O’Connor JC, Andre C, Wang Y, Lawson MA, Szegedi SS, Lestage J, et al. Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. J Neurosci. 2009;29:4200–9.
-
(2009)
J Neurosci
, vol.29
, pp. 4200-4209
-
-
O’Connor, J.C.1
Andre, C.2
Wang, Y.3
Lawson, M.A.4
Szegedi, S.S.5
Lestage, J.6
-
29
-
-
0042848767
-
Tryptophan and the immune response
-
COI: 1:CAS:528:DC%2BD3sXmvFSmtLw%3D, PID: 12848846
-
Moffett JR, Namboodiri MA. Tryptophan and the immune response. Immunol Cell Biol. 2003;81:247–65.
-
(2003)
Immunol Cell Biol
, vol.81
, pp. 247-265
-
-
Moffett, J.R.1
Namboodiri, M.A.2
-
30
-
-
84886800861
-
Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine
-
COI: 1:CAS:528:DC%2BC3sXmsFCnsLw%3D, PID: 23622958
-
Molteni R, Macchi F, Zecchillo C, Dell’agli M, Colombo E, Calabrese F, et al. Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine. Eur Neuropsychopharmacol. 2013;23:1645–55.
-
(2013)
Eur Neuropsychopharmacol
, vol.23
, pp. 1645-1655
-
-
Molteni, R.1
Macchi, F.2
Zecchillo, C.3
Dell’agli, M.4
Colombo, E.5
Calabrese, F.6
-
31
-
-
65649152524
-
Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis
-
COI: 1:CAS:528:DC%2BD1MXhsFOkt7k%3D, PID: 19188531
-
Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med. 2009;71:171–86.
-
(2009)
Psychosom Med
, vol.71
, pp. 171-186
-
-
Howren, M.B.1
Lamkin, D.M.2
Suls, J.3
-
32
-
-
84878138965
-
Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities
-
COI: 1:CAS:528:DC%2BC38Xhs1ajtbfK, PID: 23064081
-
Savitz J, Frank MB, Victor T, Bebak M, Marino JH, Bellgowan PS, et al. Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities. Brain Behav Immun. 2013;31:161–71.
-
(2013)
Brain Behav Immun
, vol.31
, pp. 161-171
-
-
Savitz, J.1
Frank, M.B.2
Victor, T.3
Bebak, M.4
Marino, J.H.5
Bellgowan, P.S.6
-
33
-
-
85021781194
-
Replicable and coupled changes in innate and adaptive immune gene expression in two case–control studies of blood microarrays in major depressive disorder
-
COI: 1:CAS:528:DC%2BC2sXhtFGiu7rK, PID: 28688579
-
Leday GGR, Vertes PE, Richardson S, Greene JR, Regan T, Khan S, et al. Replicable and coupled changes in innate and adaptive immune gene expression in two case–control studies of blood microarrays in major depressive disorder. Biol Psychiatry. 2018;83:70–80.
-
(2018)
Biol Psychiatry
, vol.83
, pp. 70-80
-
-
Leday, G.G.R.1
Vertes, P.E.2
Richardson, S.3
Greene, J.R.4
Regan, T.5
Khan, S.6
-
34
-
-
0036429161
-
Treatment of cytokine-induced depression
-
COI: 1:CAS:528:DC%2BD38XotFSgtb4%3D, PID: 12401471
-
Capuron L, Hauser P, Hinze-Selch D, Miller AH, Neveu PJ. Treatment of cytokine-induced depression. Brain Behav Immun. 2002;16:575–80.
-
(2002)
Brain Behav Immun
, vol.16
, pp. 575-580
-
-
Capuron, L.1
Hauser, P.2
Hinze-Selch, D.3
Miller, A.H.4
Neveu, P.J.5
-
35
-
-
77951878127
-
Inflammation and social experience: an inflammatory challenge induces feelings of social disconnection in addition to depressed mood
-
PID: 20043983
-
Eisenberger NI, Inagaki TK, Mashal NM, Irwin MR. Inflammation and social experience: an inflammatory challenge induces feelings of social disconnection in addition to depressed mood. Brain Behav Immun. 2010;24:558–63.
-
(2010)
Brain Behav Immun
, vol.24
, pp. 558-563
-
-
Eisenberger, N.I.1
Inagaki, T.K.2
Mashal, N.M.3
Irwin, M.R.4
-
36
-
-
78249237226
-
Association of high-sensitivity C-reactive protein with de novo major depression
-
PID: 21037214
-
Pasco JA, Nicholson GC, Williams LJ, Jacka FN, Henry MJ, Kotowicz MA, et al. Association of high-sensitivity C-reactive protein with de novo major depression. Br J Psychiatry. 2010;197:372–7.
-
(2010)
Br J Psychiatry
, vol.197
, pp. 372-377
-
-
Pasco, J.A.1
Nicholson, G.C.2
Williams, L.J.3
Jacka, F.N.4
Henry, M.J.5
Kotowicz, M.A.6
-
37
-
-
34250890185
-
Depression and the risk for cardiovascular diseases: systematic review and meta analysis
-
PID: 17236251
-
Van der Kooy K, van Hout H, Marwijk H, Marten H, Stehouwer C, Beekman A. Depression and the risk for cardiovascular diseases: systematic review and meta analysis. Int J Geriatr Psychiatry. 2007;22:613–26.
-
(2007)
Int J Geriatr Psychiatry
, vol.22
, pp. 613-626
-
-
Van der Kooy, K.1
van Hout, H.2
Marwijk, H.3
Marten, H.4
Stehouwer, C.5
Beekman, A.6
-
38
-
-
15044349248
-
Depression in multiple sclerosis: a quantitative review of the evidence
-
PID: 15769199
-
Dalton EJ, Heinrichs RW. Depression in multiple sclerosis: a quantitative review of the evidence. Neuropsychology. 2005;19:152–8.
-
(2005)
Neuropsychology
, vol.19
, pp. 152-158
-
-
Dalton, E.J.1
Heinrichs, R.W.2
-
39
-
-
84925357658
-
Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes
-
PID: 25629589
-
Setiawan E, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Rajkowska G, et al. Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes. JAMA Psychiatry. 2015;72:268–75.
-
(2015)
JAMA Psychiatry
, vol.72
, pp. 268-275
-
-
Setiawan, E.1
Wilson, A.A.2
Mizrahi, R.3
Rusjan, P.M.4
Miler, L.5
Rajkowska, G.6
-
40
-
-
85019163609
-
Neuropathology of mood disorders: do we see the stigmata of inflammation?
-
COI: 1:CAS:528:DC%2BC28XhvVemur7K, PID: 27824355
-
Mechawar N, Savitz J. Neuropathology of mood disorders: do we see the stigmata of inflammation? Transl Psychiatry. 2016;6:e946.
-
(2016)
Transl Psychiatry
, vol.6
-
-
Mechawar, N.1
Savitz, J.2
-
41
-
-
84952342629
-
The role of inflammation in depression: from evolutionary imperative to modern treatment target
-
COI: 1:CAS:528:DC%2BC2MXitV2msLfN, PID: 26711676
-
Miller AH, Raison CL. The role of inflammation in depression: from evolutionary imperative to modern treatment target. Nat Rev Immunol. 2016;16:22–34.
-
(2016)
Nat Rev Immunol
, vol.16
, pp. 22-34
-
-
Miller, A.H.1
Raison, C.L.2
-
42
-
-
84880183932
-
Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors
-
COI: 1:CAS:528:DC%2BC3sXht1yqu7fK, PID: 23866724
-
Lawson MA, Parrott JM, McCusker RH, Dantzer R, Kelley KW, O’Connor JC. Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors. J Neuroinflammation. 2013;10:87.
-
(2013)
J Neuroinflammation
, vol.10
-
-
Lawson, M.A.1
Parrott, J.M.2
McCusker, R.H.3
Dantzer, R.4
Kelley, K.W.5
O’Connor, J.C.6
-
43
-
-
84999947490
-
Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation
-
COI: 1:STN:280:DC%2BC2srhsl2lug%3D%3D, PID: 27754481
-
Parrott JM, Redus L, Santana-Coelho D, Morales J, Gao X, O’Connor JC. Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation. Transl Psychiatry. 2016;6:e918.
-
(2016)
Transl Psychiatry
, vol.6
-
-
Parrott, J.M.1
Redus, L.2
Santana-Coelho, D.3
Morales, J.4
Gao, X.5
O’Connor, J.C.6
-
44
-
-
0035985472
-
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy
-
COI: 1:CAS:528:DC%2BD38XkslKmtr8%3D, PID: 12082564
-
Capuron L, Ravaud A, Neveu PJ, Miller AH, Maes M, Dantzer R. Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy. Mol Psychiatry. 2002;7:468–73.
-
(2002)
Mol Psychiatry
, vol.7
, pp. 468-473
-
-
Capuron, L.1
Ravaud, A.2
Neveu, P.J.3
Miller, A.H.4
Maes, M.5
Dantzer, R.6
-
45
-
-
21244495606
-
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity
-
COI: 1:CAS:528:DC%2BD2MXksFejsb0%3D, PID: 15494706
-
Wichers MC, Koek GH, Robaeys G, Verkerk R, Scharpe S, Maes M. IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity. Mol Psychiatry. 2005;10:538–44.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 538-544
-
-
Wichers, M.C.1
Koek, G.H.2
Robaeys, G.3
Verkerk, R.4
Scharpe, S.5
Maes, M.6
-
46
-
-
84947447604
-
Quinolinic acid responses during interferon-alpha-induced depressive symptomatology in patients with chronic hepatitis C Infection—a novel aspect for depression and inflammatory hypothesis
-
PID: 26368809
-
Baranyi A, Meinitzer A, Breitenecker RJ, Amouzadeh-Ghadikolai O, Stauber R, Rothenhausler HB. Quinolinic acid responses during interferon-alpha-induced depressive symptomatology in patients with chronic hepatitis C Infection—a novel aspect for depression and inflammatory hypothesis. PLoS ONE. 2015;10:e0137022.
-
(2015)
PLoS One
, vol.10
-
-
Baranyi, A.1
Meinitzer, A.2
Breitenecker, R.J.3
Amouzadeh-Ghadikolai, O.4
Stauber, R.5
Rothenhausler, H.B.6
-
47
-
-
33846018443
-
Kynurenine pathway in major depression: evidence of impaired neuroprotection
-
COI: 1:CAS:528:DC%2BD2sXmtVWhtg%3D%3D, PID: 16952400
-
Myint AM, Kim YK, Verkerk R, Scharpe S, Steinbusch H, Leonard B. Kynurenine pathway in major depression: evidence of impaired neuroprotection. J Affect Disord. 2007;98:143–51.
-
(2007)
J Affect Disord
, vol.98
, pp. 143-151
-
-
Myint, A.M.1
Kim, Y.K.2
Verkerk, R.3
Scharpe, S.4
Steinbusch, H.5
Leonard, B.6
-
48
-
-
84927126178
-
Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder
-
COI: 1:CAS:528:DC%2BC2cXhsVCrsbbO, PID: 25074636
-
Savitz J, Drevets WC, Smith CM, Victor TA, Wurfel BE, Bellgowan PS, et al. Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder. Neuropsychopharmacology. 2015;40:463–71.
-
(2015)
Neuropsychopharmacology
, vol.40
, pp. 463-471
-
-
Savitz, J.1
Drevets, W.C.2
Smith, C.M.3
Victor, T.A.4
Wurfel, B.E.5
Bellgowan, P.S.6
-
49
-
-
84928824523
-
Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder
-
COI: 1:CAS:528:DC%2BC2MXivVeqtbw%3D, PID: 25686798
-
Savitz J, Drevets WC, Wurfel BE, Ford BN, Bellgowan PS, Victor TA, et al. Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain Behav Immun. 2015;46:55–59.
-
(2015)
Brain Behav Immun
, vol.46
, pp. 55-59
-
-
Savitz, J.1
Drevets, W.C.2
Wurfel, B.E.3
Ford, B.N.4
Bellgowan, P.S.5
Victor, T.A.6
-
50
-
-
85031726775
-
Serum kynurenic acid is reduced in affective psychosis
-
COI: 1:CAS:528:DC%2BC2sXnvVCkurg%3D, PID: 28463241
-
Wurfel BE, Drevets WC, Bliss SA, McMillin JR, Suzuki H, Ford BN, et al. Serum kynurenic acid is reduced in affective psychosis. Transl Psychiatry. 2017;7:e1115.
-
(2017)
Transl Psychiatry
, vol.7
-
-
Wurfel, B.E.1
Drevets, W.C.2
Bliss, S.A.3
McMillin, J.R.4
Suzuki, H.5
Ford, B.N.6
-
51
-
-
84919402536
-
A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality
-
COI: 1:CAS:528:DC%2BC2cXhtlKmtLrN, PID: 25124710
-
Bay-Richter C, Linderholm KR, Lim CK, Samuelsson M, Traskman-Bendz L, Guillemin GJ, et al. A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality. Brain Behav Immun. 2015;43:110–7.
-
(2015)
Brain Behav Immun
, vol.43
, pp. 110-117
-
-
Bay-Richter, C.1
Linderholm, K.R.2
Lim, C.K.3
Samuelsson, M.4
Traskman-Bendz, L.5
Guillemin, G.J.6
-
52
-
-
85047130137
-
Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes
-
COI: 1:CAS:528:DC%2BC1cXpvVSkur8%3D, PID: 29787958
-
Doolin K, Allers KA, Pleiner S, Liesener A, Farrell C, Tozzi L, et al. Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes. Psychoneuroendocrinology. 2018;95:8–17.
-
(2018)
Psychoneuroendocrinology
, vol.95
, pp. 8-17
-
-
Doolin, K.1
Allers, K.A.2
Pleiner, S.3
Liesener, A.4
Farrell, C.5
Tozzi, L.6
-
53
-
-
85042323797
-
Kynurenine pathway metabolism and the neurobiology of treatment-resistant depression: comparison of multiple ketamine infusions and electroconvulsive therapy
-
COI: 1:STN:280:DC%2BC1MrkslKkug%3D%3D, PID: 29475018
-
Allen AP, Naughton M, Dowling J, Walsh A, O’Shea R, Shorten G, et al. Kynurenine pathway metabolism and the neurobiology of treatment-resistant depression: comparison of multiple ketamine infusions and electroconvulsive therapy. J Psychiatr Res. 2018;100:24–32.
-
(2018)
J Psychiatr Res
, vol.100
, pp. 24-32
-
-
Allen, A.P.1
Naughton, M.2
Dowling, J.3
Walsh, A.4
O’Shea, R.5
Shorten, G.6
-
54
-
-
85014067418
-
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder
-
PID: 28241062
-
Birner A, Platzer M, Bengesser SA, Dalkner N, Fellendorf FT, Queissner R, et al. Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder. PLoS ONE. 2017;12:e0172699.
-
(2017)
PLoS One
, vol.12
-
-
Birner, A.1
Platzer, M.2
Bengesser, S.A.3
Dalkner, N.4
Fellendorf, F.T.5
Queissner, R.6
-
55
-
-
84987660627
-
Kynurenine pathway and white matter microstructure in bipolar disorder
-
PID: 27619930
-
Poletti S, Myint AM, Schuetze G, Bollettini I, Mazza E, Grillitsch D, et al. Kynurenine pathway and white matter microstructure in bipolar disorder. Eur Arch Psychiatry Clin Neurosci. 2018;268:157–68.
-
(2018)
Eur Arch Psychiatry Clin Neurosci
, vol.268
, pp. 157-168
-
-
Poletti, S.1
Myint, A.M.2
Schuetze, G.3
Bollettini, I.4
Mazza, E.5
Grillitsch, D.6
-
56
-
-
84978767426
-
Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients
-
Schwieler L, Samuelsson M, Frye MA, Bhat M, Schuppe-Koistinen I, Jungholm O, et al. Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients. J Neuroinflamm. 2016;13:51.
-
(2016)
J Neuroinflamm
, vol.13
-
-
Schwieler, L.1
Samuelsson, M.2
Frye, M.A.3
Bhat, M.4
Schuppe-Koistinen, I.5
Jungholm, O.6
-
57
-
-
80051959787
-
Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity
-
COI: 1:CAS:528:DC%2BC3MXht1SrurnI, PID: 21712776
-
Maes M, Galecki P, Verkerk R, Rief W. Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity. Neuro Endocrinol Lett. 2011;32:264–73.
-
(2011)
Neuro Endocrinol Lett
, vol.32
, pp. 264-273
-
-
Maes, M.1
Galecki, P.2
Verkerk, R.3
Rief, W.4
-
58
-
-
84970028218
-
Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge
-
PID: 27233247
-
Parrott JM, Redus L, O’Connor JC. Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge. J Neuroinflammation. 2016;13:124.
-
(2016)
J Neuroinflammation
, vol.13
-
-
Parrott, J.M.1
Redus, L.2
O’Connor, J.C.3
-
59
-
-
84959492527
-
Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder
-
COI: 1:CAS:528:DC%2BC2MXhvVKmsbvP, PID: 26546831
-
Meier TB, Drevets WC, Wurfel BE, Ford BN, Morris HM, Victor TA, et al. Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain Behav Immun. 2016;53:39–48.
-
(2016)
Brain Behav Immun
, vol.53
, pp. 39-48
-
-
Meier, T.B.1
Drevets, W.C.2
Wurfel, B.E.3
Ford, B.N.4
Morris, H.M.5
Victor, T.A.6
-
60
-
-
84977120369
-
Smaller dentate gyrus and CA2 and CA3 volumes are associated with kynurenine metabolites in collegiate football athletes
-
PID: 26493952
-
Meier TB, Savitz J, Singh R, Teague TK, Bellgowan PS. Smaller dentate gyrus and CA2 and CA3 volumes are associated with kynurenine metabolites in collegiate football athletes. J Neurotrauma. 2016;33:1349–57.
-
(2016)
J Neurotrauma
, vol.33
, pp. 1349-1357
-
-
Meier, T.B.1
Savitz, J.2
Singh, R.3
Teague, T.K.4
Bellgowan, P.S.5
-
61
-
-
84922610676
-
Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder
-
COI: 1:CAS:528:DC%2BC2cXhvF2rurbL, PID: 25486577
-
Savitz J, Dantzer R, Wurfel BE, Victor TA, Ford BN, Bodurka J, et al. Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder. Psychoneuroendocrinology. 2015;52:200–11.
-
(2015)
Psychoneuroendocrinology
, vol.52
, pp. 200-211
-
-
Savitz, J.1
Dantzer, R.2
Wurfel, B.E.3
Victor, T.A.4
Ford, B.N.5
Bodurka, J.6
-
62
-
-
84964612382
-
Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression
-
COI: 1:CAS:528:DC%2BC28XmvF2ntbk%3D, PID: 27091600
-
Young KD, Drevets WC, Dantzer R, Teague TK, Bodurka J, Savitz J. Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression. Brain Behav Immun. 2016;56:335–42.
-
(2016)
Brain Behav Immun
, vol.56
, pp. 335-342
-
-
Young, K.D.1
Drevets, W.C.2
Dantzer, R.3
Teague, T.K.4
Bodurka, J.5
Savitz, J.6
-
63
-
-
67651243648
-
The excitotoxin quinolinic acid induces tau phosphorylation in human neurons
-
PID: 19623258
-
Rahman A, Ting K, Cullen KM, Braidy N, Brew BJ, Guillemin GJ. The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. PLoS ONE. 2009;4:e6344.
-
(2009)
PLoS One
, vol.4
-
-
Rahman, A.1
Ting, K.2
Cullen, K.M.3
Braidy, N.4
Brew, B.J.5
Guillemin, G.J.6
-
64
-
-
84938635816
-
Expression of the kynurenine pathway in human peripheral blood mononuclear cells: implications for inflammatory and neurodegenerative disease
-
PID: 26114426
-
Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, et al. Expression of the kynurenine pathway in human peripheral blood mononuclear cells: implications for inflammatory and neurodegenerative disease. PLoS ONE. 2015;10:e0131389.
-
(2015)
PLoS One
, vol.10
-
-
Jones, S.P.1
Franco, N.F.2
Varney, B.3
Sundaram, G.4
Brown, D.A.5
de Bie, J.6
-
65
-
-
2442454784
-
Brain metabolic alterations in medication-free patients with bipolar disorder
-
COI: 1:CAS:528:DC%2BD2cXkslektbg%3D, PID: 15123489
-
Dager SR, Friedman SD, Parow A, Demopulos C, Stoll AL, Lyoo IK, et al. Brain metabolic alterations in medication-free patients with bipolar disorder. Arch Gen Psychiatry. 2004;61:450–8.
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 450-458
-
-
Dager, S.R.1
Friedman, S.D.2
Parow, A.3
Demopulos, C.4
Stoll, A.L.5
Lyoo, I.K.6
-
66
-
-
85019397093
-
Abnormalities in high-energy phosphate metabolism in first-episode bipolar disorder measured using (31)P-magnetic resonance spectroscopy
-
COI: 1:CAS:528:DC%2BC2sXotVCgt74%3D, PID: 28527566
-
Du F, Yuksel C, Chouinard VA, Huynh P, Ryan K, Cohen BM, et al. Abnormalities in high-energy phosphate metabolism in first-episode bipolar disorder measured using (31)P-magnetic resonance spectroscopy. Biol Psychiatry. 2018;84:797–802.
-
(2018)
Biol Psychiatry
, vol.84
, pp. 797-802
-
-
Du, F.1
Yuksel, C.2
Chouinard, V.A.3
Huynh, P.4
Ryan, K.5
Cohen, B.M.6
-
67
-
-
85060523242
-
Kynurenine 3-monooxygenase activity in human primary neurons and effect on cellular bioenergetics identifies new neurotoxic mechanisms
-
COI: 1:CAS:528:DC%2BC1MXhtVyrtr%2FI, PID: 30666558
-
Castellano-Gonzalez G, Jacobs KR, Don E, Cole NJ, Adams S, Lim CK, et al. Kynurenine 3-monooxygenase activity in human primary neurons and effect on cellular bioenergetics identifies new neurotoxic mechanisms. Neurotox Res. 2019;35:530–41.
-
(2019)
Neurotox Res
, vol.35
, pp. 530-541
-
-
Castellano-Gonzalez, G.1
Jacobs, K.R.2
Don, E.3
Cole, N.J.4
Adams, S.5
Lim, C.K.6
-
68
-
-
85031128568
-
Metabolic regulation of macrophage phenotype and function
-
COI: 1:CAS:528:DC%2BC2sXhs1Cit77J, PID: 29027220
-
Saha S, Shalova IN, Biswas SK. Metabolic regulation of macrophage phenotype and function. Immunol Rev. 2017;280:102–11.
-
(2017)
Immunol Rev
, vol.280
, pp. 102-111
-
-
Saha, S.1
Shalova, I.N.2
Biswas, S.K.3
-
69
-
-
84885377829
-
The Warburg effect then and now: from cancer to inflammatory diseases
-
COI: 1:CAS:528:DC%2BC3sXhs1eltLfJ, PID: 24115022
-
Palsson-McDermott EM, O’Neill LA. The Warburg effect then and now: from cancer to inflammatory diseases. Bioessays. 2013;35:965–73.
-
(2013)
Bioessays
, vol.35
, pp. 965-973
-
-
Palsson-McDermott, E.M.1
O’Neill, L.A.2
-
70
-
-
0021354501
-
Studies on the disposition of quinolinic acid after intracerebral or systemic administration in the rat
-
COI: 1:CAS:528:DyaL2cXktVGjsbk%3D, PID: 6232146
-
Foster AC, Miller LP, Oldendorf WH, Schwarcz R. Studies on the disposition of quinolinic acid after intracerebral or systemic administration in the rat. Exp Neurol. 1984;84:428–40.
-
(1984)
Exp Neurol
, vol.84
, pp. 428-440
-
-
Foster, A.C.1
Miller, L.P.2
Oldendorf, W.H.3
Schwarcz, R.4
-
71
-
-
84994508608
-
Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity
-
COI: 1:CAS:528:DC%2BC28XhvVahsLjO, PID: 27819338
-
Latif-Hernandez A, Shah D, Ahmed T, Lo AC, Callaerts-Vegh Z, Van der Linden A, et al. Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity. Sci Rep. 2016;6:36489.
-
(2016)
Sci Rep
, vol.6
-
-
Latif-Hernandez, A.1
Shah, D.2
Ahmed, T.3
Lo, A.C.4
Callaerts-Vegh, Z.5
Van der Linden, A.6
-
72
-
-
84942811205
-
Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine
-
COI: 1:CAS:528:DC%2BC2MXhsFSks7zE, PID: 26365611
-
Forrest CM, McNair K, Pisar M, Khalil OS, Darlington LG, Stone TW. Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine. Neuroscience. 2015;310:91–105.
-
(2015)
Neuroscience
, vol.310
, pp. 91-105
-
-
Forrest, C.M.1
McNair, K.2
Pisar, M.3
Khalil, O.S.4
Darlington, L.G.5
Stone, T.W.6
-
73
-
-
77953617514
-
Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior
-
COI: 1:CAS:528:DC%2BC3cXnsVOnsbY%3D, PID: 20336058
-
Potter MC, Elmer GI, Bergeron R, Albuquerque EX, Guidetti P, Wu HQ, et al. Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology. 2010;35:1734–42.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 1734-1742
-
-
Potter, M.C.1
Elmer, G.I.2
Bergeron, R.3
Albuquerque, E.X.4
Guidetti, P.5
Wu, H.Q.6
-
74
-
-
84880390761
-
Conceptual confluence: the kynurenine pathway as a common target for ketamine and the convergence of the inflammation and glutamate hypotheses of depression
-
COI: 1:CAS:528:DC%2BC3sXhtFCjs7fI, PID: 23857540
-
Miller AH. Conceptual confluence: the kynurenine pathway as a common target for ketamine and the convergence of the inflammation and glutamate hypotheses of depression. Neuropsychopharmacology. 2013;38:1607–8.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1607-1608
-
-
Miller, A.H.1
-
75
-
-
84880331865
-
NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice
-
COI: 1:CAS:528:DC%2BC3sXhtFCjs7nK, PID: 23511700
-
Walker AK, Budac DP, Bisulco S, Lee AW, Smith RA, Beenders B, et al. NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice. Neuropsychopharmacology. 2013;38:1609–16.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1609-1616
-
-
Walker, A.K.1
Budac, D.P.2
Bisulco, S.3
Lee, A.W.4
Smith, R.A.5
Beenders, B.6
-
76
-
-
84979690565
-
Role of inflammation in suicide: from mechanisms to treatment
-
COI: 1:CAS:528:DC%2BC28Xht12lsL%2FJ, PID: 27377015
-
Brundin L, Bryleva EY, Thirtamara Rajamani K. Role of inflammation in suicide: from mechanisms to treatment. Neuropsychopharmacology. 2017;42:271–83.
-
(2017)
Neuropsychopharmacology
, vol.42
, pp. 271-283
-
-
Brundin, L.1
Bryleva, E.Y.2
Thirtamara Rajamani, K.3
-
77
-
-
84929132678
-
The role of the kynurenine pathway in suicidality in adolescent major depressive disorder
-
COI: 1:CAS:528:DC%2BC2MXlvVGrtbo%3D, PID: 25865484
-
Bradley KA, Case JA, Khan O, Ricart T, Hanna A, Alonso CM, et al. The role of the kynurenine pathway in suicidality in adolescent major depressive disorder. Psychiatry Res. 2015;227:206–12.
-
(2015)
Psychiatry Res
, vol.227
, pp. 206-212
-
-
Bradley, K.A.1
Case, J.A.2
Khan, O.3
Ricart, T.4
Hanna, A.5
Alonso, C.M.6
-
78
-
-
84949309945
-
Combined Toxoplasma gondii seropositivity and high blood kynurenine—linked with nonfatal suicidal self-directed violence in patients with schizophrenia
-
PID: 26594873
-
Okusaga O, Duncan E, Langenberg P, Brundin L, Fuchs D, Groer MW, et al. Combined Toxoplasma gondii seropositivity and high blood kynurenine—linked with nonfatal suicidal self-directed violence in patients with schizophrenia. J Psychiatr Res. 2016;72:74–81.
-
(2016)
J Psychiatr Res
, vol.72
, pp. 74-81
-
-
Okusaga, O.1
Duncan, E.2
Langenberg, P.3
Brundin, L.4
Fuchs, D.5
Groer, M.W.6
-
79
-
-
84875211649
-
Connecting inflammation with glutamate agonism in suicidality
-
COI: 1:CAS:528:DC%2BC3sXktV2qtrk%3D, PID: 23299933
-
Erhardt S, Lim CK, Linderholm KR, Janelidze S, Lindqvist D, Samuelsson M, et al. Connecting inflammation with glutamate agonism in suicidality. Neuropsychopharmacology. 2013;38:743–52.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 743-752
-
-
Erhardt, S.1
Lim, C.K.2
Linderholm, K.R.3
Janelidze, S.4
Lindqvist, D.5
Samuelsson, M.6
-
80
-
-
81155157520
-
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?
-
COI: 1:CAS:528:DC%2BC3MXhtFyhsb3E
-
Steiner J, Walter M, Gos T, Guillemin GJ, Bernstein HG, Sarnyai Z, et al. Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? J Neuroinflamm. 2011;8:94.
-
(2011)
J Neuroinflamm
, vol.8
-
-
Steiner, J.1
Walter, M.2
Gos, T.3
Guillemin, G.J.4
Bernstein, H.G.5
Sarnyai, Z.6
-
81
-
-
84982719195
-
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
-
COI: 1:CAS:528:DC%2BC28Xht12lsbnN, PID: 27483383
-
Brundin L, Sellgren CM, Lim CK, Grit J, Palsson E, Landen M, et al. An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. Transl Psychiatry. 2016;6:e865.
-
(2016)
Transl Psychiatry
, vol.6
-
-
Brundin, L.1
Sellgren, C.M.2
Lim, C.K.3
Grit, J.4
Palsson, E.5
Landen, M.6
-
82
-
-
79956371387
-
The physiological action of picolinic acid in the human brain
-
COI: 1:CAS:528:DC%2BD1MXnslChtLo%3D, PID: 22084583
-
Grant RS, Coggan SE, Smythe GA. The physiological action of picolinic acid in the human brain. Int J Tryptophan Res. 2009;2:71–79.
-
(2009)
Int J Tryptophan Res
, vol.2
, pp. 71-79
-
-
Grant, R.S.1
Coggan, S.E.2
Smythe, G.A.3
-
83
-
-
84922233431
-
Glutamate and dopamine in schizophrenia: an update for the 21st century
-
PID: 4902122
-
Howes O, McCutcheon R, Stone J. Glutamate and dopamine in schizophrenia: an update for the 21st century. J Psychopharmacol. 2015;29:97–115.
-
(2015)
J Psychopharmacol
, vol.29
, pp. 97-115
-
-
Howes, O.1
McCutcheon, R.2
Stone, J.3
-
84
-
-
0028850552
-
Glutamate receptor dysfunction and schizophrenia
-
COI: 1:CAS:528:DyaK28XotF2rtA%3D%3D, PID: 7492260
-
Olney JW, Farber NB. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 1995;52:998–1007.
-
(1995)
Arch Gen Psychiatry
, vol.52
, pp. 998-1007
-
-
Olney, J.W.1
Farber, N.B.2
-
85
-
-
84862603083
-
Kynurenines in the mammalian brain: when physiology meets pathology
-
COI: 1:CAS:528:DC%2BC38Xot1CmsL4%3D, PID: 22678511
-
Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012;13:465–77.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 465-477
-
-
Schwarcz, R.1
Bruno, J.P.2
Muchowski, P.J.3
Wu, H.Q.4
-
86
-
-
84868092047
-
Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder
-
COI: 1:CAS:528:DC%2BC3sXktleluw%3D%3D, PID: 23030601
-
Olsson SK, Sellgren C, Engberg G, Landen M, Erhardt S. Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder. Bipolar Disord. 2012;14:719–26.
-
(2012)
Bipolar Disord
, vol.14
, pp. 719-726
-
-
Olsson, S.K.1
Sellgren, C.2
Engberg, G.3
Landen, M.4
Erhardt, S.5
-
87
-
-
84894560873
-
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression
-
COI: 1:CAS:528:DC%2BC2cXivFygt70%3D, PID: 23459468
-
Lavebratt C, Olsson S, Backlund L, Frisen L, Sellgren C, Priebe L, et al. The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression. Mol Psychiatry. 2014;19:334–41.
-
(2014)
Mol Psychiatry
, vol.19
, pp. 334-341
-
-
Lavebratt, C.1
Olsson, S.2
Backlund, L.3
Frisen, L.4
Sellgren, C.5
Priebe, L.6
-
88
-
-
33646379643
-
Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons
-
COI: 1:CAS:528:DC%2BD28XjvFGhtbY%3D, PID: 16082514
-
Nilsson LK, Linderholm KR, Erhardt S. Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons. J Neural Transm. 2006;113:557–71.
-
(2006)
J Neural Transm
, vol.113
, pp. 557-571
-
-
Nilsson, L.K.1
Linderholm, K.R.2
Erhardt, S.3
-
89
-
-
0035477818
-
Increased cortical kynurenate content in schizophrenia
-
COI: 1:CAS:528:DC%2BD3MXntlOqsLo%3D, PID: 11600105
-
Schwarcz R, Rassoulpour A, Wu HQ, Medoff D, Tamminga CA, Roberts RC. Increased cortical kynurenate content in schizophrenia. Biol Psychiatry. 2001;50:521–30.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 521-530
-
-
Schwarcz, R.1
Rassoulpour, A.2
Wu, H.Q.3
Medoff, D.4
Tamminga, C.A.5
Roberts, R.C.6
-
90
-
-
0035798252
-
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
-
COI: 1:CAS:528:DC%2BD3MXnslWrs7Y%3D, PID: 11684348
-
Erhardt S, Blennow K, Nordin C, Skogh E, Lindstrom LH, Engberg G. Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci Lett. 2001;313:96–98.
-
(2001)
Neurosci Lett
, vol.313
, pp. 96-98
-
-
Erhardt, S.1
Blennow, K.2
Nordin, C.3
Skogh, E.4
Lindstrom, L.H.5
Engberg, G.6
-
91
-
-
84860159640
-
Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia
-
PID: 20729465
-
Linderholm KR, Skogh E, Olsson SK, Dahl ML, Holtze M, Engberg G, et al. Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia. Schizophr Bull. 2012;38:426–32.
-
(2012)
Schizophr Bull
, vol.38
, pp. 426-432
-
-
Linderholm, K.R.1
Skogh, E.2
Olsson, S.K.3
Dahl, M.L.4
Holtze, M.5
Engberg, G.6
-
92
-
-
85021819812
-
Kynurenic acid in Schizophrenia: a systematic review and meta-analysis
-
PID: 28187219
-
Plitman E, Iwata Y, Caravaggio F, Nakajima S, Chung JK, Gerretsen P, et al. Kynurenic acid in Schizophrenia: a systematic review and meta-analysis. Schizophr Bull. 2017;43:764–77.
-
(2017)
Schizophr Bull
, vol.43
, pp. 764-777
-
-
Plitman, E.1
Iwata, Y.2
Caravaggio, F.3
Nakajima, S.4
Chung, J.K.5
Gerretsen, P.6
-
93
-
-
84885997463
-
Inflammation and schizophrenia
-
PID: 24072812
-
Kirkpatrick B, Miller BJ. Inflammation and schizophrenia. Schizophr Bull. 2013;39:1174–9.
-
(2013)
Schizophr Bull
, vol.39
, pp. 1174-1179
-
-
Kirkpatrick, B.1
Miller, B.J.2
-
94
-
-
84954204064
-
Microglial activity in people at ultra high risk of psychosis and in Schizophrenia: an [(11)C]PBR28 PET Brain Imaging Study
-
PID: 26472628
-
Bloomfield PS, Selvaraj S, Veronese M, Rizzo G, Bertoldo A, Owen DR, et al. Microglial activity in people at ultra high risk of psychosis and in Schizophrenia: an [(11)C]PBR28 PET Brain Imaging Study. Am J Psychiatry. 2016;173:44–52.
-
(2016)
Am J Psychiatry
, vol.173
, pp. 44-52
-
-
Bloomfield, P.S.1
Selvaraj, S.2
Veronese, M.3
Rizzo, G.4
Bertoldo, A.5
Owen, D.R.6
-
95
-
-
80053900888
-
Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naive and medication-free schizophrenic patients
-
COI: 1:CAS:528:DC%2BC3MXht12itr3N, PID: 21620952
-
Myint AM, Schwarz MJ, Verkerk R, Mueller HH, Zach J, Scharpe S, et al. Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naive and medication-free schizophrenic patients. Brain Behav Immun. 2011;25:1576–81.
-
(2011)
Brain Behav Immun
, vol.25
, pp. 1576-1581
-
-
Myint, A.M.1
Schwarz, M.J.2
Verkerk, R.3
Mueller, H.H.4
Zach, J.5
Scharpe, S.6
-
96
-
-
0021968646
-
The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes
-
COI: 1:CAS:528:DyaL2MXkvFyqt70%3D, PID: 3899109
-
Salter M, Pogson CI. The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes. Biochem J. 1985;229:499–504.
-
(1985)
Biochem J
, vol.229
, pp. 499-504
-
-
Salter, M.1
Pogson, C.I.2
-
97
-
-
85046429193
-
Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia
-
COI: 1:CAS:528:DC%2BC1cXht1CgtLvN, PID: 29728648
-
Chiappelli J, Rowland LM, Notarangelo FM, Wijtenburg SA, Thomas MAR, Pocivavsek A, et al. Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology. 2018;43:1706–11.
-
(2018)
Neuropsychopharmacology
, vol.43
, pp. 1706-1711
-
-
Chiappelli, J.1
Rowland, L.M.2
Notarangelo, F.M.3
Wijtenburg, S.A.4
Thomas, M.A.R.5
Pocivavsek, A.6
-
98
-
-
85026847787
-
Novel blood-based biomarkers of cognition, stress, and physical or cognitive training in older adults at risk of dementia: preliminary evidence for a role of BDNF, irisin, and the kynurenine pathway
-
PID: 28731451
-
Kuster OC, Laptinskaya D, Fissler P, Schnack C, Zugel M, Nold V, et al. Novel blood-based biomarkers of cognition, stress, and physical or cognitive training in older adults at risk of dementia: preliminary evidence for a role of BDNF, irisin, and the kynurenine pathway. J Alzheimers Dis. 2017;59:1097–111.
-
(2017)
J Alzheimers Dis
, vol.59
, pp. 1097-1111
-
-
Kuster, O.C.1
Laptinskaya, D.2
Fissler, P.3
Schnack, C.4
Zugel, M.5
Nold, V.6
-
99
-
-
84933556000
-
Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory
-
COI: 1:CAS:528:DC%2BC2MXhtFWgtrfN, PID: 26130057
-
Heisler JM, O’Connor JC. Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory. Brain Behav Immun. 2015;50:115–24.
-
(2015)
Brain Behav Immun
, vol.50
, pp. 115-124
-
-
Heisler, J.M.1
O’Connor, J.C.2
-
100
-
-
85018737280
-
Tryptophan breakdown and cognition in bipolar disorder
-
COI: 1:CAS:528:DC%2BC2sXnvVynsbY%3D, PID: 28482311
-
Platzer M, Dalkner N, Fellendorf FT, Birner A, Bengesser SA, Queissner R, et al. Tryptophan breakdown and cognition in bipolar disorder. Psychoneuroendocrinology. 2017;81:144–50.
-
(2017)
Psychoneuroendocrinology
, vol.81
, pp. 144-150
-
-
Platzer, M.1
Dalkner, N.2
Fellendorf, F.T.3
Birner, A.4
Bengesser, S.A.5
Queissner, R.6
-
101
-
-
4143096940
-
Endogenous kynurenic acid disrupts prepulse inhibition
-
COI: 1:CAS:528:DC%2BD2cXmslegtbg%3D, PID: 15312813
-
Erhardt S, Schwieler L, Emanuelsson C, Geyer M. Endogenous kynurenic acid disrupts prepulse inhibition. Biol Psychiatry. 2004;56:255–60.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 255-260
-
-
Erhardt, S.1
Schwieler, L.2
Emanuelsson, C.3
Geyer, M.4
-
102
-
-
80052710746
-
Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory
-
COI: 1:CAS:528:DC%2BC3MXhtFyms7bN, PID: 21796108
-
Pocivavsek A, Wu HQ, Potter MC, Elmer GI, Pellicciari R, Schwarcz R. Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory. Neuropsychopharmacology. 2011;36:2357–67.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 2357-2367
-
-
Pocivavsek, A.1
Wu, H.Q.2
Potter, M.C.3
Elmer, G.I.4
Pellicciari, R.5
Schwarcz, R.6
-
103
-
-
84858445314
-
Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
-
COI: 1:CAS:528:DC%2BC3MXhtlyrtrzN, PID: 22038535
-
Alexander KS, Wu HQ, Schwarcz R, Bruno JP. Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine. Psychopharmacology. 2012;220:627–37.
-
(2012)
Psychopharmacology
, vol.220
, pp. 627-637
-
-
Alexander, K.S.1
Wu, H.Q.2
Schwarcz, R.3
Bruno, J.P.4
-
104
-
-
84928267091
-
Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia
-
PID: 25464917
-
Wonodi I, McMahon RP, Krishna N, Mitchell BD, Liu J, Glassman M, et al. Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia. Schizophr Res. 2014;160:80–87.
-
(2014)
Schizophr Res
, vol.160
, pp. 80-87
-
-
Wonodi, I.1
McMahon, R.P.2
Krishna, N.3
Mitchell, B.D.4
Liu, J.5
Glassman, M.6
-
105
-
-
84864772397
-
Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression
-
COI: 1:CAS:528:DC%2BC38Xht1SisrnN, PID: 22751107
-
Kim H, Chen L, Lim G, Sung B, Wang S, McCabe MF, et al. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest. 2012;122:2940–54.
-
(2012)
J Clin Invest
, vol.122
, pp. 2940-2954
-
-
Kim, H.1
Chen, L.2
Lim, G.3
Sung, B.4
Wang, S.5
McCabe, M.F.6
-
106
-
-
84973333836
-
Virus infections incite pain hypersensitivity by inducing indoleamine 2,3 dioxygenase
-
PID: 27168185
-
Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, et al. Virus infections incite pain hypersensitivity by inducing indoleamine 2,3 dioxygenase. PLoS Pathog. 2016;12:e1005615.
-
(2016)
PLoS Pathog
, vol.12
-
-
Huang, L.1
Ou, R.2
Rabelo de Souza, G.3
Cunha, T.M.4
Lemos, H.5
Mohamed, E.6
-
108
-
-
85025600838
-
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain
-
COI: 1:CAS:528:DC%2BC2sXht1Cjsr7L, PID: 28709913
-
Laumet G, Zhou W, Dantzer R, Edralin JD, Huo X, Budac DP, et al. Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain. Brain Behav Immun. 2017;66:94–102.
-
(2017)
Brain Behav Immun
, vol.66
, pp. 94-102
-
-
Laumet, G.1
Zhou, W.2
Dantzer, R.3
Edralin, J.D.4
Huo, X.5
Budac, D.P.6
-
109
-
-
84890964966
-
Neuroinflammation and comorbidity of pain and depression
-
COI: 1:CAS:528:DC%2BC2cXovVyks7w%3D, PID: 24335193
-
Walker AK, Kavelaars A, Heijnen CJ, Dantzer R. Neuroinflammation and comorbidity of pain and depression. Pharmacol Rev. 2014;66:80–101.
-
(2014)
Pharmacol Rev
, vol.66
, pp. 80-101
-
-
Walker, A.K.1
Kavelaars, A.2
Heijnen, C.J.3
Dantzer, R.4
-
110
-
-
61749084966
-
Relationships among depression, chronic pain, chronic disabling pain, and medical costs
-
PID: 19252047
-
Arnow BA, Blasey CM, Lee J, Fireman B, Hunkeler EM, Dea R, et al. Relationships among depression, chronic pain, chronic disabling pain, and medical costs. Psychiatr Serv. 2009;60:344–50.
-
(2009)
Psychiatr Serv
, vol.60
, pp. 344-350
-
-
Arnow, B.A.1
Blasey, C.M.2
Lee, J.3
Fireman, B.4
Hunkeler, E.M.5
Dea, R.6
-
111
-
-
34447616978
-
Pain in depression: STAR*D study findings
-
PID: 17662746
-
Husain MM, Rush AJ, Trivedi MH, McClintock SM, Wisniewski SR, Davis L, et al. Pain in depression: STAR*D study findings. J Psychosom Res. 2007;63:113–22.
-
(2007)
J Psychosom Res
, vol.63
, pp. 113-122
-
-
Husain, M.M.1
Rush, A.J.2
Trivedi, M.H.3
McClintock, S.M.4
Wisniewski, S.R.5
Davis, L.6
-
112
-
-
84871925048
-
Kynurenines in the CNS: recent advances and new questions
-
COI: 1:CAS:528:DC%2BC38XhvVektb3E, PID: 23237916
-
Vecsei L, Szalardy L, Fulop F, Toldi J. Kynurenines in the CNS: recent advances and new questions. Nat Rev Drug Discov. 2013;12:64–82.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 64-82
-
-
Vecsei, L.1
Szalardy, L.2
Fulop, F.3
Toldi, J.4
-
113
-
-
85049461974
-
Hypothesis kynurenic and quinolinic acids: the main players of the kynurenine pathway and opponents in inflammatory disease
-
COI: 1:CAS:528:DC%2BC1cXht12ls77E, PID: 30037600
-
Badawy AA. Hypothesis kynurenic and quinolinic acids: the main players of the kynurenine pathway and opponents in inflammatory disease. Med Hypotheses. 2018;118:129–38.
-
(2018)
Med Hypotheses
, vol.118
, pp. 129-138
-
-
Badawy, A.A.1
-
114
-
-
84996780872
-
The end of the road for the tryptophan depletion concept in pregnancy and infection
-
COI: 1:CAS:528:DC%2BC28XhtFWhs77F, PID: 27358028
-
Badawy AA, Namboodiri AM, Moffett JR. The end of the road for the tryptophan depletion concept in pregnancy and infection. Clin Sci. 2016;130:1327–33.
-
(2016)
Clin Sci
, vol.130
, pp. 1327-1333
-
-
Badawy, A.A.1
Namboodiri, A.M.2
Moffett, J.R.3
-
115
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
COI: 1:CAS:528:DyaK1cXls1Cqu7c%3D, PID: 9712583
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 1998;281:1191–3.
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
116
-
-
84877082935
-
Implication of indolamine 2,3 dioxygenase in the tolerance toward fetuses, tumors, and allografts
-
COI: 1:CAS:528:DC%2BC3sXntVCntLs%3D, PID: 23325926
-
Durr S, Kindler V. Implication of indolamine 2,3 dioxygenase in the tolerance toward fetuses, tumors, and allografts. J Leukoc Biol. 2013;93:681–7.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 681-687
-
-
Durr, S.1
Kindler, V.2
-
117
-
-
84949675877
-
Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements
-
COI: 1:CAS:528:DC%2BC2MXitVSksb%2FM, PID: 26617070
-
Badawy AA. Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements. Neuropharmacology. 2017;112:248–63.
-
(2017)
Neuropharmacology
, vol.112
, pp. 248-263
-
-
Badawy, A.A.1
-
118
-
-
85021066782
-
Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: association with sleep disturbance
-
COI: 1:CAS:528:DC%2BC2sXhtVKnsbzP, PID: 28645775
-
Suzuki H, Savitz J, Kent Teague T, Gandhapudi SK, Tan C, Misaki M, et al. Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: association with sleep disturbance. Brain Behav Immun. 2017;66:193–200.
-
(2017)
Brain Behav Immun
, vol.66
, pp. 193-200
-
-
Suzuki, H.1
Savitz, J.2
Kent Teague, T.3
Gandhapudi, S.K.4
Tan, C.5
Misaki, M.6
-
119
-
-
0027102159
-
Depression and reduced natural killer cytotoxicity: a longitudinal study of depressed patients and control subjects
-
COI: 1:STN:280:DyaK3s7ktFKrug%3D%3D, PID: 1488477
-
Irwin M, Lacher U, Caldwell C. Depression and reduced natural killer cytotoxicity: a longitudinal study of depressed patients and control subjects. Psychol Med. 1992;22:1045–50.
-
(1992)
Psychol Med
, vol.22
, pp. 1045-1050
-
-
Irwin, M.1
Lacher, U.2
Caldwell, C.3
-
120
-
-
0025864320
-
Psychological stress and susceptibility to the common cold
-
COI: 1:STN:280:DyaK3MzhvFWktA%3D%3D, PID: 1713648
-
Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med. 1991;325:606–12.
-
(1991)
N Engl J Med
, vol.325
, pp. 606-612
-
-
Cohen, S.1
Tyrrell, D.A.2
Smith, A.P.3
-
121
-
-
84875685408
-
Varicella zoster virus-specific immune responses to a herpes zoster vaccine in elderly recipients with major depression and the impact of antidepressant medications
-
COI: 1:CAS:528:DC%2BC3sXksFKqsbc%3D, PID: 23413415
-
Irwin MR, Levin MJ, Laudenslager ML, Olmstead R, Lucko A, Lang N, et al. Varicella zoster virus-specific immune responses to a herpes zoster vaccine in elderly recipients with major depression and the impact of antidepressant medications. Clin Infect Dis. 2013;56:1085–93.
-
(2013)
Clin Infect Dis
, vol.56
, pp. 1085-1093
-
-
Irwin, M.R.1
Levin, M.J.2
Laudenslager, M.L.3
Olmstead, R.4
Lucko, A.5
Lang, N.6
-
122
-
-
85044190233
-
Reduced immunity to measles in adults with major depressive disorder
-
PID: 29552990
-
Ford BN, Yolken RH, Dickerson FB, Teague TK, Irwin MR, Paulus MP et al. Reduced immunity to measles in adults with major depressive disorder. Psychol Med. 2019;49:243–49.
-
(2018)
Psychological Medicine
, vol.49
, Issue.2
, pp. 243-249
-
-
Ford, B.N.1
Yolken, R.H.2
Dickerson, F.B.3
Teague, T.K.4
Irwin, M.R.5
Paulus, M.P.6
Savitz, J.7
-
123
-
-
70449369312
-
Depression as a predictor of disease progression and mortality in cancer patients: a meta-analysis
-
PID: 19753617
-
Satin JR, Linden W, Phillips MJ. Depression as a predictor of disease progression and mortality in cancer patients: a meta-analysis. Cancer. 2009;115:5349–61.
-
(2009)
Cancer
, vol.115
, pp. 5349-5361
-
-
Satin, J.R.1
Linden, W.2
Phillips, M.J.3
-
124
-
-
20344369025
-
Measurement of tryptophan, kynurenine and neopterin in women with and without postpartum blues
-
COI: 1:CAS:528:DC%2BD2MXltFensL8%3D, PID: 15935232
-
Kohl C, Walch T, Huber R, Kemmler G, Neurauter G, Fuchs D, et al. Measurement of tryptophan, kynurenine and neopterin in women with and without postpartum blues. J Affect Disord. 2005;86:135–42.
-
(2005)
J Affect Disord
, vol.86
, pp. 135-142
-
-
Kohl, C.1
Walch, T.2
Huber, R.3
Kemmler, G.4
Neurauter, G.5
Fuchs, D.6
-
125
-
-
32944465245
-
Decreased brain tryptophan availability as a partial determinant of post-partum blues
-
COI: 1:CAS:528:DC%2BD28Xhsl2jt70%3D, PID: 16303256
-
Bailara KM, Henry C, Lestage J, Launay JM, Parrot F, Swendsen J, et al. Decreased brain tryptophan availability as a partial determinant of post-partum blues. Psychoneuroendocrinology. 2006;31:407–13.
-
(2006)
Psychoneuroendocrinology
, vol.31
, pp. 407-413
-
-
Bailara, K.M.1
Henry, C.2
Lestage, J.3
Launay, J.M.4
Parrot, F.5
Swendsen, J.6
-
126
-
-
84943620715
-
Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression
-
COI: 1:CAS:528:DC%2BC2MXhs1Sht7zM, PID: 26454336
-
Veen C, Myint AM, Burgerhout KM, Schwarz MJ, Schutze G, Kushner SA, et al. Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression. J Affect Disord. 2016;189:298–305.
-
(2016)
J Affect Disord
, vol.189
, pp. 298-305
-
-
Veen, C.1
Myint, A.M.2
Burgerhout, K.M.3
Schwarz, M.J.4
Schutze, G.5
Kushner, S.A.6
-
127
-
-
85015630394
-
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women
-
COI: 1:CAS:528:DC%2BC2sXksFCnt7s%3D, PID: 28319697
-
Wang SY, Duan KM, Tan XF, Yin JY, Mao XY, Zheng W, et al. Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. J Affect Disord. 2017;215:94–101.
-
(2017)
J Affect Disord
, vol.215
, pp. 94-101
-
-
Wang, S.Y.1
Duan, K.M.2
Tan, X.F.3
Yin, J.Y.4
Mao, X.Y.5
Zheng, W.6
-
128
-
-
85053872821
-
The weight of nutrients: kynurenine metabolites in obesity and exercise
-
COI: 1:STN:280:DC%2BB3c3hsVKhtg%3D%3D, PID: 30141532
-
Dadvar S, Ferreira DMS, Cervenka I, Ruas JL. The weight of nutrients: kynurenine metabolites in obesity and exercise. J Intern Med. 2018;284:519–33.
-
(2018)
J Intern Med
, vol.284
, pp. 519-533
-
-
Dadvar, S.1
Ferreira, D.M.S.2
Cervenka, I.3
Ruas, J.L.4
-
129
-
-
85048952408
-
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health
-
COI: 1:CAS:528:DC%2BC1cXht1WqsLjF, PID: 29942089
-
Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S, et al. Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. Nat Med. 2018;24:1113–20.
-
(2018)
Nat Med
, vol.24
, pp. 1113-1120
-
-
Laurans, L.1
Venteclef, N.2
Haddad, Y.3
Chajadine, M.4
Alzaid, F.5
Metghalchi, S.6
-
130
-
-
84885321044
-
Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways
-
COI: 1:CAS:528:DC%2BC3sXhsV2itLjJ, PID: 23813101
-
Oxenkrug G. Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways. Mol Neurobiol. 2013;48:294–301.
-
(2013)
Mol Neurobiol
, vol.48
, pp. 294-301
-
-
Oxenkrug, G.1
-
131
-
-
84920955894
-
Kynurenic acid is a nutritional cue that enables behavioral plasticity
-
COI: 1:CAS:528:DC%2BC2MXhtF2lsb4%3D, PID: 25594177
-
Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. Kynurenic acid is a nutritional cue that enables behavioral plasticity. Cell. 2015;160:119–31.
-
(2015)
Cell
, vol.160
, pp. 119-131
-
-
Lemieux, G.A.1
Cunningham, K.A.2
Lin, L.3
Mayer, F.4
Werb, Z.5
Ashrafi, K.6
-
132
-
-
85044767398
-
Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation
-
COI: 1:CAS:528:DC%2BC1cXjvFymu7s%3D, PID: 29414686
-
Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, et al. Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation. Cell Metab. 2018;27:378–92.
-
(2018)
Cell Metab
, vol.27
, pp. 378-392
-
-
Agudelo, L.Z.1
Ferreira, D.M.S.2
Cervenka, I.3
Bryzgalova, G.4
Dadvar, S.5
Jannig, P.R.6
-
133
-
-
85042087646
-
Depression and obesity: evidence of shared biological mechanisms
-
PID: 29453413
-
Milaneschi Y, Simmons WK, van Rossum EFC, Penninx BW. Depression and obesity: evidence of shared biological mechanisms. Mol Psychiatry. 2019;24:18–33.
-
(2018)
Molecular Psychiatry
, vol.24
, Issue.1
, pp. 18-33
-
-
Milaneschi, Y.1
Simmons, W.K.2
van Rossum, E.F.C.3
Penninx, B.W.J.H.4
-
134
-
-
84981186248
-
Role of adiposity-driven inflammation in depressive morbidity
-
COI: 1:CAS:528:DC%2BC28XhtlGmsb%2FP, PID: 27402495
-
Capuron L, Lasselin J, Castanon N. Role of adiposity-driven inflammation in depressive morbidity. Neuropsychopharmacology. 2017;42:115–28.
-
(2017)
Neuropsychopharmacology
, vol.42
, pp. 115-128
-
-
Capuron, L.1
Lasselin, J.2
Castanon, N.3
-
136
-
-
84989900719
-
Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes
-
COI: 1:CAS:528:DC%2BC28Xhs1Skt7nP, PID: 26946084
-
Mudry JM, Alm PS, Erhardt S, Goiny M, Fritz T, Caidahl K, et al. Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes. Diabetes Metab Res Rev. 2016;32:754–61.
-
(2016)
Diabetes Metab Res Rev
, vol.32
, pp. 754-761
-
-
Mudry, J.M.1
Alm, P.S.2
Erhardt, S.3
Goiny, M.4
Fritz, T.5
Caidahl, K.6
-
137
-
-
85052685542
-
Association of tryptophan metabolites with incident type 2 diabetes in the PREDIMED trial: a case-cohort study
-
COI: 1:CAS:528:DC%2BC1cXit1yktrrN, PID: 29884676
-
Yu E, Papandreou C, Ruiz-Canela M, Guasch-Ferre M, Clish CB, Dennis C, et al. Association of tryptophan metabolites with incident type 2 diabetes in the PREDIMED trial: a case-cohort study. Clin Chem. 2018;64:1211–20.
-
(2018)
Clin Chem
, vol.64
, pp. 1211-1220
-
-
Yu, E.1
Papandreou, C.2
Ruiz-Canela, M.3
Guasch-Ferre, M.4
Clish, C.B.5
Dennis, C.6
-
138
-
-
84942835576
-
The kynurenine pathway is activated in human obesity and shifted tward kynurenine mono-oxygenase activation
-
COI: 1:CAS:528:DC%2BC2MXhs1Srur%2FO, PID: 26347385
-
Favennec M, Hennart B, Caiazzo R, Leloire A, Yengo L, Verbanck M, et al. The kynurenine pathway is activated in human obesity and shifted tward kynurenine mono-oxygenase activation. Obesity. 2015;23:2066–74.
-
(2015)
Obesity
, vol.23
, pp. 2066-2074
-
-
Favennec, M.1
Hennart, B.2
Caiazzo, R.3
Leloire, A.4
Yengo, L.5
Verbanck, M.6
-
139
-
-
84959500135
-
The Mitochondrial basis of aging
-
COI: 1:CAS:528:DC%2BC28Xjslyiu7g%3D, PID: 26942670
-
Sun N, Youle RJ, Finkel T. The Mitochondrial basis of aging. Mol Cell. 2016;61:654–66.
-
(2016)
Mol Cell
, vol.61
, pp. 654-666
-
-
Sun, N.1
Youle, R.J.2
Finkel, T.3
-
140
-
-
84923138740
-
New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond
-
COI: 1:CAS:528:DC%2BC2MXivVaqtro%3D, PID: 25495651
-
Villena JA. New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond. FEBS J. 2015;282:647–72.
-
(2015)
FEBS J
, vol.282
, pp. 647-672
-
-
Villena, J.A.1
-
141
-
-
84907486069
-
Skeletal muscle PGC-1alpha1 modulates kynurenine metabolism and mediates resilience to stress-induced depression
-
COI: 1:CAS:528:DC%2BC2cXhs1GmtLfE, PID: 25259918
-
Agudelo LZ, Femenia T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, et al. Skeletal muscle PGC-1alpha1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 2014;159:33–45.
-
(2014)
Cell
, vol.159
, pp. 33-45
-
-
Agudelo, L.Z.1
Femenia, T.2
Orhan, F.3
Porsmyr-Palmertz, M.4
Goiny, M.5
Martinez-Redondo, V.6
-
142
-
-
84929289074
-
The kynurenine pathway and neurodegenerative disease
-
COI: 1:CAS:528:DC%2BC2MXks1arsLs%3D, PID: 25773161
-
Maddison DC, Giorgini F. The kynurenine pathway and neurodegenerative disease. Semin Cell Dev Biol. 2015;40:134–41.
-
(2015)
Semin Cell Dev Biol
, vol.40
, pp. 134-141
-
-
Maddison, D.C.1
Giorgini, F.2
-
143
-
-
84963971832
-
Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease
-
COI: 1:CAS:528:DC%2BC28Xms1KrtLs%3D, PID: 27072742
-
Lim CK, Fernandez-Gomez FJ, Braidy N, Estrada C, Costa C, Costa S, et al. Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease. Prog Neurobiol. 2017;155:76–95.
-
(2017)
Prog Neurobiol
, vol.155
, pp. 76-95
-
-
Lim, C.K.1
Fernandez-Gomez, F.J.2
Braidy, N.3
Estrada, C.4
Costa, C.5
Costa, S.6
-
144
-
-
33846228447
-
Decreased serum and red blood cell kynurenic acid levels in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2sXnslCksw%3D%3D, PID: 17023091
-
Hartai Z, Juhasz A, Rimanoczy A, Janaky T, Donko T, Dux L, et al. Decreased serum and red blood cell kynurenic acid levels in Alzheimer’s disease. Neurochem Int. 2007;50:308–13.
-
(2007)
Neurochem Int
, vol.50
, pp. 308-313
-
-
Hartai, Z.1
Juhasz, A.2
Rimanoczy, A.3
Janaky, T.4
Donko, T.5
Dux, L.6
-
145
-
-
0026671306
-
Kynurenine pathway abnormalities in Parkinson’s disease
-
COI: 1:CAS:528:DyaK3sXnvVGhsQ%3D%3D, PID: 1513457
-
Ogawa T, Matson WR, Beal MF, Myers RH, Bird ED, Milbury P, et al. Kynurenine pathway abnormalities in Parkinson’s disease. Neurology. 1992;42:1702–6.
-
(1992)
Neurology
, vol.42
, pp. 1702-1706
-
-
Ogawa, T.1
Matson, W.R.2
Beal, M.F.3
Myers, R.H.4
Bird, E.D.5
Milbury, P.6
-
146
-
-
85032807606
-
Is the enzyme ACMSD a novel therapeutic target in parkinson’s disease?
-
COI: 1:CAS:528:DC%2BC2sXhslGrt7fE, PID: 29103054
-
Thirtamara-Rajamani K, Li P, Escobar Galvis ML, Labrie V, Brundin P, Brundin L. Is the enzyme ACMSD a novel therapeutic target in parkinson’s disease? J Parkinsons Dis. 2017;7:577–87.
-
(2017)
J Parkinsons Dis
, vol.7
, pp. 577-587
-
-
Thirtamara-Rajamani, K.1
Li, P.2
Escobar Galvis, M.L.3
Labrie, V.4
Brundin, P.5
Brundin, L.6
-
147
-
-
79958021894
-
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration
-
COI: 1:CAS:528:DC%2BC3MXnsVOkt74%3D, PID: 21640374
-
Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, et al. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell. 2011;145:863–74.
-
(2011)
Cell
, vol.145
, pp. 863-874
-
-
Zwilling, D.1
Huang, S.Y.2
Sathyasaikumar, K.V.3
Notarangelo, F.M.4
Guidetti, P.5
Wu, H.Q.6
-
148
-
-
36248936617
-
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys
-
COI: 1:CAS:528:DC%2BD2sXhtlCrurfO, PID: 17868931
-
Gregoire L, Rassoulpour A, Guidetti P, Samadi P, Bedard PJ, Izzo E, et al. Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys. Behav Brain Res. 2008;186:161–7.
-
(2008)
Behav Brain Res
, vol.186
, pp. 161-167
-
-
Gregoire, L.1
Rassoulpour, A.2
Guidetti, P.3
Samadi, P.4
Bedard, P.J.5
Izzo, E.6
-
149
-
-
79958044624
-
The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington’s disease
-
COI: 1:CAS:528:DC%2BC3MXntFKmtr8%3D, PID: 21636279
-
Campesan S, Green EW, Breda C, Sathyasaikumar KV, Muchowski PJ, Schwarcz R, et al. The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington’s disease. Curr Biol. 2011;21:961–6.
-
(2011)
Curr Biol
, vol.21
, pp. 961-966
-
-
Campesan, S.1
Green, E.W.2
Breda, C.3
Sathyasaikumar, K.V.4
Muchowski, P.J.5
Schwarcz, R.6
-
150
-
-
85022341613
-
Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity
-
COI: 1:CAS:528:DC%2BC2sXlvFCnsLk%3D, PID: 28401650
-
Sutphin GL, Backer G, Sheehan S, Bean S, Corban C, Liu T, et al. Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity. Aging Cell. 2017;16:672–82.
-
(2017)
Aging Cell
, vol.16
, pp. 672-682
-
-
Sutphin, G.L.1
Backer, G.2
Sheehan, S.3
Bean, S.4
Corban, C.5
Liu, T.6
-
151
-
-
84929023781
-
Molecular signatures of major depression
-
COI: 1:CAS:528:DC%2BC2MXntFKjsbk%3D, PID: 25913401
-
Cai N, Chang S, Li Y, Li Q, Hu J, Liang J, et al. Molecular signatures of major depression. Curr Biol. 2015;25:1146–56.
-
(2015)
Curr Biol
, vol.25
, pp. 1146-1156
-
-
Cai, N.1
Chang, S.2
Li, Y.3
Li, Q.4
Hu, J.5
Liang, J.6
-
152
-
-
84952333092
-
Depression as a risk factor for Alzheimer’s disease: genes, steroids, cytokines and neurogenesis—What do we need to know?
-
COI: 1:CAS:528:DC%2BC28XitFSqtw%3D%3D, PID: 26746105
-
Herbert J, Lucassen PJ. Depression as a risk factor for Alzheimer’s disease: genes, steroids, cytokines and neurogenesis—What do we need to know? Front Neuroendocrinol. 2016;41:153–71.
-
(2016)
Front Neuroendocrinol
, vol.41
, pp. 153-171
-
-
Herbert, J.1
Lucassen, P.J.2
-
153
-
-
84931094799
-
Depression and subsequent risk of Parkinson disease: a nationwide cohort study
-
PID: 25995056
-
Gustafsson H, Nordstrom A, Nordstrom P. Depression and subsequent risk of Parkinson disease: a nationwide cohort study. Neurology. 2015;84:2422–9.
-
(2015)
Neurology
, vol.84
, pp. 2422-2429
-
-
Gustafsson, H.1
Nordstrom, A.2
Nordstrom, P.3
-
154
-
-
84983036037
-
Sex differences in immune responses
-
COI: 1:CAS:528:DC%2BC28XhtlChsLfE, PID: 27546235
-
Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16:626–38.
-
(2016)
Nat Rev Immunol
, vol.16
, pp. 626-638
-
-
Klein, S.L.1
Flanagan, K.L.2
-
155
-
-
67849128689
-
Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis
-
COI: 1:CAS:528:DC%2BD1MXptVaqs70%3D, PID: 19279650
-
Hewagama A, Patel D, Yarlagadda S, Strickland FM, Richardson BC. Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis. Genes Immun. 2009;10:509–16.
-
(2009)
Genes Immun
, vol.10
, pp. 509-516
-
-
Hewagama, A.1
Patel, D.2
Yarlagadda, S.3
Strickland, F.M.4
Richardson, B.C.5
-
156
-
-
85050266072
-
Sex hormones regulate innate immune cells and promote sex differences in respiratory virus infection
-
PID: 30079065
-
Kadel S, Kovats S. Sex hormones regulate innate immune cells and promote sex differences in respiratory virus infection. Front Immunol. 2018;9:1653.
-
(2018)
Front Immunol
, vol.9
, pp. 1653
-
-
Kadel, S.1
Kovats, S.2
-
157
-
-
0005831155
-
Estrogen-enzyme interactions: Inhibition and protection of kynurenine transaminase by the sulfate esters of diethylstilbestrol, estradiol, and estrone
-
COI: 1:CAS:528:DyaF3cXhtFWjtro%3D, PID: 14422057
-
Mason M, Gullekson EH. Estrogen-enzyme interactions: Inhibition and protection of kynurenine transaminase by the sulfate esters of diethylstilbestrol, estradiol, and estrone. J Biol Chem. 1960;235:1312–6.
-
(1960)
J Biol Chem
, vol.235
, pp. 1312-1316
-
-
Mason, M.1
Gullekson, E.H.2
-
158
-
-
85038253712
-
Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives
-
PID: 29242525
-
Jayawickrama GS, Nematollahi A, Sun G, Gorrell MD, Church WB. Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives. Sci Rep. 2017;7:17559.
-
(2017)
Sci Rep
, vol.7
-
-
Jayawickrama, G.S.1
Nematollahi, A.2
Sun, G.3
Gorrell, M.D.4
Church, W.B.5
-
159
-
-
21244436362
-
Preliminary array analysis reveals novel genes regulated by ovarian steroids in the monkey raphe region
-
COI: 1:CAS:528:DC%2BD2MXksVGjsbY%3D, PID: 15731897
-
Reddy AP, Bethea CL. Preliminary array analysis reveals novel genes regulated by ovarian steroids in the monkey raphe region. Psychopharmacology. 2005;180:125–40.
-
(2005)
Psychopharmacology
, vol.180
, pp. 125-140
-
-
Reddy, A.P.1
Bethea, C.L.2
-
160
-
-
85009923563
-
Progesterone alters kynurenine pathway activation in IFN-gamma-activated macrophages—relevance for neuroinflammatory diseases
-
PID: 27980422
-
de Bie J, Lim CK, Guillemin GJ. Progesterone alters kynurenine pathway activation in IFN-gamma-activated macrophages—relevance for neuroinflammatory diseases. Int J Tryptophan Res. 2016;9:89–93.
-
(2016)
Int J Tryptophan Res
, vol.9
, pp. 89-93
-
-
de Bie, J.1
Lim, C.K.2
Guillemin, G.J.3
-
161
-
-
0037341830
-
Epidemiology of women and depression
-
PID: 12646294
-
Kessler RC. Epidemiology of women and depression. J Affect Disord. 2003;74:5–13.
-
(2003)
J Affect Disord
, vol.74
, pp. 5-13
-
-
Kessler, R.C.1
-
162
-
-
85028658074
-
Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression
-
COI: 1:CAS:528:DC%2BC2sXhsVeis7bF, PID: 28867283
-
Meier TB, Drevets WC, Teague TK, Wurfel BE, Mueller SC, Bodurka J, et al. Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression. Brain Behav Immun. 2018;67:59–64.
-
(2018)
Brain Behav Immun
, vol.67
, pp. 59-64
-
-
Meier, T.B.1
Drevets, W.C.2
Teague, T.K.3
Wurfel, B.E.4
Mueller, S.C.5
Bodurka, J.6
-
163
-
-
77957571306
-
Sex differences in the brain, behavior, and neuropsychiatric disorders
-
PID: 20889965
-
Bao AM, Swaab DF. Sex differences in the brain, behavior, and neuropsychiatric disorders. Neuroscientist. 2010;16:550–65.
-
(2010)
Neuroscientist
, vol.16
, pp. 550-565
-
-
Bao, A.M.1
Swaab, D.F.2
-
164
-
-
84997724674
-
Targeting the indoleamine 2,3-dioxygenase pathway in cancer
-
PID: 26674411
-
Moon YW, Hajjar J, Hwu P, Naing A. Targeting the indoleamine 2,3-dioxygenase pathway in cancer. J Immunother Cancer. 2015;3:51.
-
(2015)
J Immunother Cancer
, vol.3
, pp. 51
-
-
Moon, Y.W.1
Hajjar, J.2
Hwu, P.3
Naing, A.4
-
165
-
-
84946882333
-
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model
-
COI: 1:CAS:528:DC%2BC2MXhvVehsbrF, PID: 26524415
-
Rojewska E, Piotrowska A, Makuch W, Przewlocka B, Mika J. Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model. Neuropharmacology. 2016;102:80–91.
-
(2016)
Neuropharmacology
, vol.102
, pp. 80-91
-
-
Rojewska, E.1
Piotrowska, A.2
Makuch, W.3
Przewlocka, B.4
Mika, J.5
-
166
-
-
85057448614
-
A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems
-
PID: 30447328
-
Wilkinson ST, Sanacora G. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discov Today. 2018;24:606–15.
-
(2018)
Drug Discov Today
, vol.24
, pp. 606-615
-
-
Wilkinson, S.T.1
Sanacora, G.2
-
167
-
-
85049605993
-
Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice
-
Walker AK, Wing EE, Banks WA, Dantzer R. Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice. Mol Psychiatry. 2018. 10.1038/s41380-018-0076-7. [Epub ahead of print].
-
(2018)
Molecular Psychiatry
, vol.24
, Issue.10
, pp. 1523-1532
-
-
Walker, A.K.1
Wing, E.E.2
Banks, W.A.3
Dantzer, R.4
-
168
-
-
84942981227
-
The impact of electroconvulsive therapy on the tryptophan-kynurenine metabolic pathway
-
COI: 1:CAS:528:DC%2BC2MXktlSktro%3D, PID: 25765557
-
Guloksuz S, Arts B, Walter S, Drukker M, Rodriguez L, Myint AM, et al. The impact of electroconvulsive therapy on the tryptophan-kynurenine metabolic pathway. Brain Behav Immun. 2015;48:48–52.
-
(2015)
Brain Behav Immun
, vol.48
, pp. 48-52
-
-
Guloksuz, S.1
Arts, B.2
Walter, S.3
Drukker, M.4
Rodriguez, L.5
Myint, A.M.6
-
169
-
-
85052064503
-
Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects
-
COI: 1:CAS:528:DC%2BC1cXhsFeiu7zO, PID: 30116859
-
Moaddel R, Shardell M, Khadeer M, Lovett J, Kadriu B, Ravichandran S, et al. Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects. Psychopharmacology. 2018;235:3017–30.
-
(2018)
Psychopharmacology
, vol.235
, pp. 3017-3030
-
-
Moaddel, R.1
Shardell, M.2
Khadeer, M.3
Lovett, J.4
Kadriu, B.5
Ravichandran, S.6
-
170
-
-
85053145412
-
Antidepressant effect of repeated ketamine administration on kynurenine pathway metabolites in patients with unipolar and bipolar depression
-
COI: 1:CAS:528:DC%2BC1cXhslWgsLvI, PID: 30213652
-
Zhou Y, Zheng W, Liu W, Wang C, Zhan Y, Li H, et al. Antidepressant effect of repeated ketamine administration on kynurenine pathway metabolites in patients with unipolar and bipolar depression. Brain Behav Immun. 2018;74:205–12.
-
(2018)
Brain Behav Immun
, vol.74
, pp. 205-212
-
-
Zhou, Y.1
Zheng, W.2
Liu, W.3
Wang, C.4
Zhan, Y.5
Li, H.6
-
171
-
-
85040331723
-
Exercise and the prevention of depression: results of the HUNT Cohort Study
-
PID: 28969440
-
Harvey SB, Overland S, Hatch SL, Wessely S, Mykletun A, Hotopf M. Exercise and the prevention of depression: results of the HUNT Cohort Study. Am J Psychiatry. 2018;175:28–36.
-
(2018)
Am J Psychiatry
, vol.175
, pp. 28-36
-
-
Harvey, S.B.1
Overland, S.2
Hatch, S.L.3
Wessely, S.4
Mykletun, A.5
Hotopf, M.6
-
172
-
-
84912098988
-
Exercise as an add-on strategy for the treatment of major depressive disorder: a systematic review
-
PID: 24589012
-
Mura G, Moro MF, Patten SB, Carta MG. Exercise as an add-on strategy for the treatment of major depressive disorder: a systematic review. CNS Spectr. 2014;19:496–508.
-
(2014)
CNS Spectr
, vol.19
, pp. 496-508
-
-
Mura, G.1
Moro, M.F.2
Patten, S.B.3
Carta, M.G.4
-
173
-
-
84983792035
-
Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans
-
PID: 27030575
-
Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, et al. Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans. Am J Physiol Cell Physiol. 2016;310:C836–40.
-
(2016)
Am J Physiol Cell Physiol
, vol.310
, pp. C836-C840
-
-
Schlittler, M.1
Goiny, M.2
Agudelo, L.Z.3
Venckunas, T.4
Brazaitis, M.5
Skurvydas, A.6
-
174
-
-
85050275872
-
Acute and chronic effects of exercise on the kynurenine pathway in humans—a brief review and future perspectives
-
COI: 1:CAS:528:DC%2BC1cXhtlyitbnF, PID: 30031753
-
Metcalfe AJ, Koliamitra C, Javelle F, Bloch W, Zimmer P. Acute and chronic effects of exercise on the kynurenine pathway in humans—a brief review and future perspectives. Physiol Behav. 2018;194:583–7.
-
(2018)
Physiol Behav
, vol.194
, pp. 583-587
-
-
Metcalfe, A.J.1
Koliamitra, C.2
Javelle, F.3
Bloch, W.4
Zimmer, P.5
-
175
-
-
84857822431
-
Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial
-
PID: 22357572
-
Savitz J, Preskorn S, Teague TK, Drevets D, Yates W, Drevets W. Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. BMJ Open. 2012;2:e000643.
-
(2012)
BMJ Open
, vol.2
-
-
Savitz, J.1
Preskorn, S.2
Teague, T.K.3
Drevets, D.4
Yates, W.5
Drevets, W.6
-
176
-
-
85040971598
-
Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2x2 double-blind, randomized, placebo-controlled, phase IIA clinical trial
-
PID: 29362444
-
Savitz JB, Teague TK, Misaki M, Macaluso M, Wurfel BE, Meyer M, et al. Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2x2 double-blind, randomized, placebo-controlled, phase IIA clinical trial. Transl Psychiatry. 2018;8:27.
-
(2018)
Transl Psychiatry
, vol.8
-
-
Savitz, J.B.1
Teague, T.K.2
Misaki, M.3
Macaluso, M.4
Wurfel, B.E.5
Meyer, M.6
-
177
-
-
0034047074
-
Glutamate and kynurenate in the rat central nervous system following treatments with tail ischaemia or diclofenac
-
COI: 1:CAS:528:DC%2BD3cXhslKrt7c%3D, PID: 10716604
-
Edwards SR, Mather LE, Lin Y, Power I, Cousins MJ. Glutamate and kynurenate in the rat central nervous system following treatments with tail ischaemia or diclofenac. J Pharm Pharmacol. 2000;52:59–66.
-
(2000)
J Pharm Pharmacol
, vol.52
, pp. 59-66
-
-
Edwards, S.R.1
Mather, L.E.2
Lin, Y.3
Power, I.4
Cousins, M.J.5
-
178
-
-
20944441781
-
Prostaglandin-mediated control of rat brain kynurenic acid synthesis—opposite actions by COX-1 and COX-2 isoforms
-
COI: 1:CAS:528:DC%2BD2MXksl2hur0%3D, PID: 15517427
-
Schwieler L, Erhardt S, Erhardt C, Engberg G. Prostaglandin-mediated control of rat brain kynurenic acid synthesis—opposite actions by COX-1 and COX-2 isoforms. J Neural Transm. 2005;112:863–72.
-
(2005)
J Neural Transm
, vol.112
, pp. 863-872
-
-
Schwieler, L.1
Erhardt, S.2
Erhardt, C.3
Engberg, G.4
-
179
-
-
84873494073
-
The kynurenine pathway: a missing piece in the puzzle of valproate action?
-
COI: 1:CAS:528:DC%2BC3sXjtFSlu7k%3D, PID: 23305763
-
Maciejak P, Szyndler J, Turzynska D, Sobolewska A, Kolosowska K, Lehner M, et al. The kynurenine pathway: a missing piece in the puzzle of valproate action? Neuroscience. 2013;234:135–45.
-
(2013)
Neuroscience
, vol.234
, pp. 135-145
-
-
Maciejak, P.1
Szyndler, J.2
Turzynska, D.3
Sobolewska, A.4
Kolosowska, K.5
Lehner, M.6
-
180
-
-
84872015298
-
Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
-
PID: 22895526
-
Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, et al. Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis. J Histochem Cytochem. 2012;60:854–60.
-
(2012)
J Histochem Cytochem
, vol.60
, pp. 854-860
-
-
Fukunaga, M.1
Yamamoto, Y.2
Kawasoe, M.3
Arioka, Y.4
Murakami, Y.5
Hoshi, M.6
-
181
-
-
84896516675
-
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation
-
COI: 1:CAS:528:DC%2BC2cXhtVyit7vK, PID: 24402311
-
Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LM, et al. IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. Int Immunol. 2014;26:357–67.
-
(2014)
Int Immunol
, vol.26
, pp. 357-367
-
-
Metz, R.1
Smith, C.2
DuHadaway, J.B.3
Chandler, P.4
Baban, B.5
Merlo, L.M.6
-
182
-
-
0030887550
-
Activated human microglia produce the excitotoxin quinolinic acid
-
COI: 1:CAS:528:DyaK2sXisVaisrY%3D, PID: 9080423
-
Espey MG, Chernyshev ON, Reinhard JF Jr., Namboodiri MA, Colton CA. Activated human microglia produce the excitotoxin quinolinic acid. Neuroreport. 1997;8:431–4.
-
(1997)
Neuroreport
, vol.8
, pp. 431-434
-
-
Espey, M.G.1
Chernyshev, O.N.2
Reinhard, J.F.3
Namboodiri, M.A.4
Colton, C.A.5
-
183
-
-
0035123904
-
Kynurenines in the CNS: from endogenous obscurity to therapeutic importance
-
COI: 1:CAS:528:DC%2BD3MXhs1aqsbY%3D, PID: 11240212
-
Stone TW. Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Prog Neurobiol. 2001;64:185–218.
-
(2001)
Prog Neurobiol
, vol.64
, pp. 185-218
-
-
Stone, T.W.1
-
184
-
-
33750699056
-
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function
-
PID: 16902152
-
Della Chiesa M, Carlomagno S, Frumento G, Balsamo M, Cantoni C, Conte R, et al. The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. Blood. 2006;108:4118–25.
-
(2006)
Blood
, vol.108
, pp. 4118-4125
-
-
Della Chiesa, M.1
Carlomagno, S.2
Frumento, G.3
Balsamo, M.4
Cantoni, C.5
Conte, R.6
-
185
-
-
19344377474
-
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
-
COI: 1:CAS:528:DC%2BD2MXkslOqtr8%3D, PID: 15894280
-
Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity. 2005;22:633–42.
-
(2005)
Immunity
, vol.22
, pp. 633-642
-
-
Munn, D.H.1
Sharma, M.D.2
Baban, B.3
Harding, H.P.4
Zhang, Y.5
Ron, D.6
-
186
-
-
70149101645
-
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells
-
COI: 1:CAS:528:DC%2BD1MXpsVKgtLw%3D, PID: 19635913
-
Baban B, Chandler PR, Sharma MD, Pihkala J, Koni PA, Munn DH, et al. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J Immunol. 2009;183:2475–83.
-
(2009)
J Immunol
, vol.183
, pp. 2475-2483
-
-
Baban, B.1
Chandler, P.R.2
Sharma, M.D.3
Pihkala, J.4
Koni, P.A.5
Munn, D.H.6
-
187
-
-
67649216127
-
The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity
-
COI: 1:CAS:528:DC%2BD1MXmslCns7g%3D, PID: 19494274
-
Scott GN, DuHadaway J, Pigott E, Ridge N, Prendergast GC, Muller AJ, et al. The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity. J Immunol. 2009;182:7509–17.
-
(2009)
J Immunol
, vol.182
, pp. 7509-7517
-
-
Scott, G.N.1
DuHadaway, J.2
Pigott, E.3
Ridge, N.4
Prendergast, G.C.5
Muller, A.J.6
|