NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice

Neuropsychopharmacology

Volumn 38, Issue 9, 2013, Pages 1609-1616

  Walker, Adam K ^a,c   Budac, David P ^b   Bisulco, Stephanie ^b   Lee, Anna W ^b   Smith, Robin A ^a   Beenders, Brent ^a   Kelley, Keith W ^a   Dantzer, Robert ^a,c  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b LUNDBECK RESEARCH USA   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

AMPA receptor; depression; inflammation; ketamine; lipopolysaccharide; NMDA receptor

Indexed keywords

2,3 DIHYDROXY 6 NITRO 7 SULFAMOYLBENZO(F)QUINOXALINE 2,3 DIONE; AMPA RECEPTOR ANTAGONIST; BRAIN DERIVED NEUROTROPHIC FACTOR; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 6; KETAMINE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; LIPOPOLYSACCHARIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; QUINOLINIC ACID; SUCROSE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; FOOD INTAKE; FORCED SWIMMING TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILLNESS BEHAVIOR; LOCOMOTION; LOW DRUG DOSE; MALE; MASS SPECTROMETRY; MOTOR ACTIVITY; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS; BODY WEIGHT; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYTOKINES; DEPRESSION; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; EATING; EXCITATORY AMINO ACID ANTAGONISTS; FOOD PREFERENCES; IMMOBILITY RESPONSE, TONIC; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KETAMINE; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; QUINOXALINES; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 84880331865     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.71     Document Type: Article

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