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Volumn 33, Issue 1, 2019, Pages 41-54

Enzymes inhibitors from natural sources with antidiabetic activity: A review

Author keywords

diabetes; drug design; enzyme inhibitors; medicinal plants; natural products

Indexed keywords

ABELMOSCHUS MOSCHATUS EXTRACT; ADVANCED GLYCATION END PRODUCT; ALANGIUM SALVIFOLIUM EXTRACT; ALDEHYDE REDUCTASE; ALPHA GLUCOSIDASE; AMYLASE; ANTIDIABETIC AGENT; AZADIRACHTA INDICA EXTRACT; BIDENS PILOSA EXTRACT; BOERHAAVIA DIFFUSA EXTRACT; CAPSICUM FRUTESCENS EXTRACT; CASSIA ALATA EXTRACT; ECLIPTA ALBA EXTRACT; EMBLICA OFFICINALIS EXTRACT; ENZYME INHIBITOR; FICUS CARICA EXTRACT; GENTIANA OLIVIER EXTRACT; GLUCOSE 6 PHOSPHATE; GLUCOSE TRANSPORTER 4; GLYCYRRHIZA GLABRA EXTRACT; GYMNEMA SYLVESTRE EXTRACT; HEXOKINASE; HORDEUM VULGARE EXTRACT; IPOMOEA AQUATICA EXTRACT; JUNIPERUS COMMUNIS EXTRACT; MANGIFERA INDICA EXTRACT; NATURAL PRODUCT; PHYTOCHEMICAL; PLANT EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL PRODUCT;

EID: 85056272014     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.6211     Document Type: Review
Times cited : (124)

References (94)
  • 1
    • 84885990491 scopus 로고    scopus 로고
    • Comparative study of in-vitro antioxidant and antidiabetic activity of plant extracts of Acacia arabica, Murraya koeingii, Catharanthus roseus and Rouwolfia serpentina
    • Aadil, K. R., Barapatre, A., Rathore, N., Pottam, S., & Jha, H. (2012). Comparative study of in-vitro antioxidant and antidiabetic activity of plant extracts of Acacia arabica, Murraya koeingii, Catharanthus roseus and Rouwolfia serpentina. International Journal of Phytomedicine, 4(4), 543.
    • (2012) International Journal of Phytomedicine , vol.4 , Issue.4 , pp. 543
    • Aadil, K.R.1    Barapatre, A.2    Rathore, N.3    Pottam, S.4    Jha, H.5
  • 2
    • 84886626639 scopus 로고    scopus 로고
    • Antimicrobial and selected in vitro enzyme inhibitory effects of leaf extracts, flavonols and indole alkaloids isolated from Croton menyharthii
    • Aderogba, M. A., Ndhlala, A. R., Rengasamy, K. R., & Van Staden, J. (2013). Antimicrobial and selected in vitro enzyme inhibitory effects of leaf extracts, flavonols and indole alkaloids isolated from Croton menyharthii. Molecules, 18(10), 12633–12644.
    • (2013) Molecules , vol.18 , Issue.10 , pp. 12633-12644
    • Aderogba, M.A.1    Ndhlala, A.R.2    Rengasamy, K.R.3    Van Staden, J.4
  • 4
    • 84976512673 scopus 로고
    • Pharmacology of α-glucosidase inhibition
    • AG,HBB (1994). Pharmacology of α-glucosidase inhibition. European Journal of Clinical Investigation, 24(S3), 3–10.
    • (1994) European Journal of Clinical Investigation , vol.24 , Issue.S3 , pp. 3-10
  • 5
    • 84863676599 scopus 로고    scopus 로고
    • Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity
    • Ajayi, A., Akhigbe, R., Adewumi, O., Okeleji, L., Mujaidu, K., & Olaleye, S. (2012). Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity. Indian Journal of Endocrinology and Metabolism, 16(Suppl1), S91.
    • (2012) Indian Journal of Endocrinology and Metabolism , vol.16 , Issue.Suppl1 , pp. S91
    • Ajayi, A.1    Akhigbe, R.2    Adewumi, O.3    Okeleji, L.4    Mujaidu, K.5    Olaleye, S.6
  • 6
    • 33748565005 scopus 로고    scopus 로고
    • α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes: With particular reference to Phyllanthus amarus
    • Ali, H., Houghton, P., & Soumyanath, A. (2006). α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes: With particular reference to Phyllanthus amarus. Journal of Ethnopharmacology, 107(3), 449–455.
    • (2006) Journal of Ethnopharmacology , vol.107 , Issue.3 , pp. 449-455
    • Ali, H.1    Houghton, P.2    Soumyanath, A.3
  • 7
    • 77954176088 scopus 로고    scopus 로고
    • Aloe emodin glycosides stimulates glucose transport and glycogen storage through PI3K dependent mechanism in L6 myotubes and inhibited the adipocyte differentiation in 3T3L1 adipocytes
    • Anand, S., Muthusamy, V., Sujatha, S., Sangeetha, K., Bharathi Raja, R., Sudhagar, S., … Lakshmi, B. S. (2010). Aloe emodin glycosides stimulates glucose transport and glycogen storage through PI3K dependent mechanism in L6 myotubes and inhibited the adipocyte differentiation in 3T3L1 adipocytes. FEBS Letters, 584(14), 3170–3178. https://doi.org/10.1016/j.febslet.2010.06.004
    • (2010) FEBS Letters , vol.584 , Issue.14 , pp. 3170-3178
    • Anand, S.1    Muthusamy, V.2    Sujatha, S.3    Sangeetha, K.4    Bharathi Raja, R.5    Sudhagar, S.6    Lakshmi, B.S.7
  • 9
    • 80052698364 scopus 로고    scopus 로고
    • Antidiabetic properties of Azardiracta indica and Bougainvillea spectabilis: In vivo studies in murine diabetes model
    • Bhat, M., Kothiwale, S. K., Tirmale, A. R., Bhargava, S. Y., & Joshi, B. N. (2011). Antidiabetic properties of Azardiracta indica and Bougainvillea spectabilis: In vivo studies in murine diabetes model. Evidence-based Complementary and Alternative Medicine, 2011, 1–9. https://doi.org/10.1093/ecam/nep033
    • (2011) Evidence-based Complementary and Alternative Medicine , vol.2011 , pp. 1-9
    • Bhat, M.1    Kothiwale, S.K.2    Tirmale, A.R.3    Bhargava, S.Y.4    Joshi, B.N.5
  • 10
    • 34249071640 scopus 로고    scopus 로고
    • Medicinal plants with potential antidiabetic activity—A review of ten years of herbal medicine research (1990-2000)
    • Bnouham, M., Ziyyat, A., Mekhfi, H., Tahri, A., & Legssyer, A. (2006). Medicinal plants with potential antidiabetic activity—A review of ten years of herbal medicine research (1990-2000). International Journal of Diabetes and Metabolism, 14(1), 1.
    • (2006) International Journal of Diabetes and Metabolism , vol.14 , Issue.1 , pp. 1
    • Bnouham, M.1    Ziyyat, A.2    Mekhfi, H.3    Tahri, A.4    Legssyer, A.5
  • 12
    • 84884193035 scopus 로고    scopus 로고
    • Beta cell dysfunction and insulin resistance
    • Cerf, M. E. (2013). Beta cell dysfunction and insulin resistance. Frontiers in Endocrinology, 4, 37.
    • (2013) Frontiers in Endocrinology , vol.4 , pp. 37
    • Cerf, M.E.1
  • 13
    • 85018774596 scopus 로고    scopus 로고
    • Rapid screening for α-glucosidase inhibitors from Gymnema sylvestre by affinity ultrafiltration—HPLC-MS
    • Chen, G., & Guo, M. (2017). Rapid screening for α-glucosidase inhibitors from Gymnema sylvestre by affinity ultrafiltration—HPLC-MS. Frontiers in Pharmacology, 8, 228. https://doi.org/10.3389/fphar.2017.00228
    • (2017) Frontiers in Pharmacology , vol.8 , pp. 228
    • Chen, G.1    Guo, M.2
  • 14
    • 84900525425 scopus 로고    scopus 로고
    • In vitro inhibitory effects of cranberry bean (Phaseolus vulgaris L.) extracts on aldose reductase, α-glucosidase and α-amylase
    • Chiang, Y. C., Chen, C. L., Jeng, T. L., & Sung, J. M. (2014). In vitro inhibitory effects of cranberry bean (Phaseolus vulgaris L.) extracts on aldose reductase, α-glucosidase and α-amylase. International Journal of Food Science and Technology, 49(6), 1470–1479.
    • (2014) International Journal of Food Science and Technology , vol.49 , Issue.6 , pp. 1470-1479
    • Chiang, Y.C.1    Chen, C.L.2    Jeng, T.L.3    Sung, J.M.4
  • 15
    • 7944222897 scopus 로고    scopus 로고
    • The role of the renin-angiotensin-aldosterone system in diabetes and its vascular complications
    • Cooper, M. E. (2004). The role of the renin-angiotensin-aldosterone system in diabetes and its vascular complications. American Journal of Hypertension, 17(S2), 16S–20S.
    • (2004) American Journal of Hypertension , vol.17 , Issue.S2 , pp. 16S-20S
    • Cooper, M.E.1
  • 16
    • 84861881199 scopus 로고    scopus 로고
    • Antihyperglycemic effect of Annona squamosa hexane extract in type 2 diabetes animal model: PTP1B inhibition, a possible mechanism of action?
    • Davis, J. A., Sharma, S., Mittra, S., Sujatha, S., Kanaujia, A., Shukla, G., … Bhatnagar, P. K. (2012). Antihyperglycemic effect of Annona squamosa hexane extract in type 2 diabetes animal model: PTP1B inhibition, a possible mechanism of action? Indian Journal of Pharmacology, 44(3), 326–332. https://doi.org/10.4103/0253-7613.96304
    • (2012) Indian Journal of Pharmacology , vol.44 , Issue.3 , pp. 326-332
    • Davis, J.A.1    Sharma, S.2    Mittra, S.3    Sujatha, S.4    Kanaujia, A.5    Shukla, G.6    Bhatnagar, P.K.7
  • 17
    • 84890514220 scopus 로고    scopus 로고
    • Helichrysum and grapefruit extracts inhibit carbohydrate digestion and absorption, improving postprandial glucose levels and hyperinsulinemia in rats
    • de la Garza, A. L., Etxeberria, U., Lostao, M. P., San Román, B. N., Barrenetxe, J., Martínez, J. A., & Milagro, F. (2013). Helichrysum and grapefruit extracts inhibit carbohydrate digestion and absorption, improving postprandial glucose levels and hyperinsulinemia in rats. Journal of Agricultural and Food Chemistry, 61(49), 12012–12019. https://doi.org/10.1021/jf4021569
    • (2013) Journal of Agricultural and Food Chemistry , vol.61 , Issue.49 , pp. 12012-12019
    • de la Garza, A.L.1    Etxeberria, U.2    Lostao, M.P.3    San Román, B.N.4    Barrenetxe, J.5    Martínez, J.A.6    Milagro, F.7
  • 18
    • 84919641978 scopus 로고    scopus 로고
    • Exploration of natural enzyme inhibitors with hypoglycemic potentials amongst Eucalyptus Spp. by in vitro assays
    • Dey, B., Mitra, A., Katakam, P., & Singla, R. K. (2014). Exploration of natural enzyme inhibitors with hypoglycemic potentials amongst Eucalyptus Spp. by in vitro assays. World Journal of Diabetes, 5(2), 209.
    • (2014) World Journal of Diabetes , vol.5 , Issue.2 , pp. 209
    • Dey, B.1    Mitra, A.2    Katakam, P.3    Singla, R.K.4
  • 19
    • 0033857113 scopus 로고    scopus 로고
    • Aldose reductase and the role of the polyol pathway in diabetic nephropathy
    • Dunlop, M. (2000). Aldose reductase and the role of the polyol pathway in diabetic nephropathy. Kidney International, 58, S3–S12.
    • (2000) Kidney International , vol.58 , pp. S3-S12
    • Dunlop, M.1
  • 20
    • 34447642375 scopus 로고    scopus 로고
    • Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites
    • El-Kabbani, O., & Podjarny, A. (2007). Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites. Cellular and Molecular Life Sciences, 64(15), 1970–1978.
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.15 , pp. 1970-1978
    • El-Kabbani, O.1    Podjarny, A.2
  • 21
    • 84906935517 scopus 로고    scopus 로고
    • The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations
    • Ezuruike, U. F., & Prieto, J. M. (2014). The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations. Journal of Ethnopharmacology, 155(2), 857–924.
    • (2014) Journal of Ethnopharmacology , vol.155 , Issue.2 , pp. 857-924
    • Ezuruike, U.F.1    Prieto, J.M.2
  • 24
    • 0015929739 scopus 로고
    • The sorbitol pathway and the complications of diabetes
    • Gabbay, K. H. (1973). The sorbitol pathway and the complications of diabetes. New England Journal of Medicine, 288(16), 831–836.
    • (1973) New England Journal of Medicine , vol.288 , Issue.16 , pp. 831-836
    • Gabbay, K.H.1
  • 25
    • 85039747534 scopus 로고    scopus 로고
    • Telomerase inhibitors from natural products and their anticancer potential
    • Ganesan, K., & Xu, B. (2017). Telomerase inhibitors from natural products and their anticancer potential. International Journal of Molecular Sciences, 19(1), 13.
    • (2017) International Journal of Molecular Sciences , vol.19 , Issue.1 , pp. 13
    • Ganesan, K.1    Xu, B.2
  • 26
    • 57149100792 scopus 로고    scopus 로고
    • Antidiabetic and ameliorative potential of Ficus bengalensis bark extract in streptozotocin induced diabetic rats
    • Gayathri, M., & Kannabiran, K. (2008). Antidiabetic and ameliorative potential of Ficus bengalensis bark extract in streptozotocin induced diabetic rats. Indian Journal of Clinical Biochemistry, 23(4), 394–400.
    • (2008) Indian Journal of Clinical Biochemistry , vol.23 , Issue.4 , pp. 394-400
    • Gayathri, M.1    Kannabiran, K.2
  • 27
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • Goldin, A., Beckman, J. A., Schmidt, A. M., & Creager, M. A. (2006). Advanced glycation end products: Sparking the development of diabetic vascular injury. Circulation, 114(6), 597–605.
    • (2006) Circulation , vol.114 , Issue.6 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 28
    • 84862303984 scopus 로고    scopus 로고
    • Enzyme inhibitory and antioxidant activities of traditional medicinal plants: Potential application in the management of hyperglycemia
    • Gulati, V., Harding, I. H., & Palombo, E. A. (2012). Enzyme inhibitory and antioxidant activities of traditional medicinal plants: Potential application in the management of hyperglycemia. BMC Complementary and Alternative Medicine, 12(1), 77.
    • (2012) BMC Complementary and Alternative Medicine , vol.12 , Issue.1 , pp. 77
    • Gulati, V.1    Harding, I.H.2    Palombo, E.A.3
  • 29
    • 0037221179 scopus 로고    scopus 로고
    • Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice
    • Gum, R. J., Gaede, L. L., Koterski, S. L., Heindel, M., Clampit, J. E., Zinker, B. A., … Rondinone, C. M. (2003). Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice. Diabetes, 52(1), 21–28.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 21-28
    • Gum, R.J.1    Gaede, L.L.2    Koterski, S.L.3    Heindel, M.4    Clampit, J.E.5    Zinker, B.A.6    Rondinone, C.M.7
  • 30
    • 84926380237 scopus 로고    scopus 로고
    • Chemical profile and inhibition of α-glycosidase and protein tyrosine phosphatase 1B (PTP1B) activities by flavonoids from licorice (Glycyrrhiza uralensis Fisch)
    • Guo, Z., Niu, X., Xiao, T., Lu, J., Li, W., & Zhao, Y. (2015). Chemical profile and inhibition of α-glycosidase and protein tyrosine phosphatase 1B (PTP1B) activities by flavonoids from licorice (Glycyrrhiza uralensis Fisch). Journal of Functional Foods, 14, 324–336.
    • (2015) Journal of Functional Foods , vol.14 , pp. 324-336
    • Guo, Z.1    Niu, X.2    Xiao, T.3    Lu, J.4    Li, W.5    Zhao, Y.6
  • 31
    • 84969195350 scopus 로고    scopus 로고
    • Stimulation of phenolics, antioxidant and α-glucosidase inhibitory activities during barley (Hordeum vulgare L.) seed germination
    • Ha, K.-S., Jo, S.-H., Mannam, V., Kwon, Y.-I., & Apostolidis, E. (2016). Stimulation of phenolics, antioxidant and α-glucosidase inhibitory activities during barley (Hordeum vulgare L.) seed germination. Plant Foods for Human Nutrition, 71(2), 211–217.
    • (2016) Plant Foods for Human Nutrition , vol.71 , Issue.2 , pp. 211-217
    • Ha, K.-S.1    Jo, S.-H.2    Mannam, V.3    Kwon, Y.-I.4    Apostolidis, E.5
  • 33
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 glucose transporter
    • Huang, S., & Czech, M. P. (2007). The GLUT4 glucose transporter. Cell Metabolism, 5(4), 237–252.
    • (2007) Cell Metabolism , vol.5 , Issue.4 , pp. 237-252
    • Huang, S.1    Czech, M.P.2
  • 34
    • 84868695818 scopus 로고    scopus 로고
    • Antidiabetic effect of Eclipta alba associated with the inhibition of alpha-glucosidase and aldose reductase
    • Jaiswal, N., Bhatia, V., Srivastava, S. P., Srivastava, A. K., & Tamrakar, A. K. (2012). Antidiabetic effect of Eclipta alba associated with the inhibition of alpha-glucosidase and aldose reductase. Natural Product Research, 26(24), 2363–2367.
    • (2012) Natural Product Research , vol.26 , Issue.24 , pp. 2363-2367
    • Jaiswal, N.1    Bhatia, V.2    Srivastava, S.P.3    Srivastava, A.K.4    Tamrakar, A.K.5
  • 36
    • 84922356798 scopus 로고    scopus 로고
    • Aqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters
    • Kabir, A. U., Samad, M. B., Ahmed, A., Jahan, M. R., Akhter, F., Tasnim, J., … Hannan, J. M. A. (2015). Aqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters. PLoS One, 10(2), e0116546. https://doi.org/10.1371/journal.pone.0116546
    • (2015) PLoS One , vol.10 , Issue.2
    • Kabir, A.U.1    Samad, M.B.2    Ahmed, A.3    Jahan, M.R.4    Akhter, F.5    Tasnim, J.6    Hannan, J.M.A.7
  • 37
    • 33748915431 scopus 로고    scopus 로고
    • Inhibitory effects of Zingiber officinale Roscoe derived components on aldose reductase activity in vitro and in vivo
    • Kato, A., Higuchi, Y., Goto, H., Kizu, H., Okamoto, T., Asano, N., … Adachi, I. (2006). Inhibitory effects of Zingiber officinale Roscoe derived components on aldose reductase activity in vitro and in vivo. Journal of Agricultural and Food Chemistry, 54(18), 6640–6644. https://doi.org/10.1021/jf061599a
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.18 , pp. 6640-6644
    • Kato, A.1    Higuchi, Y.2    Goto, H.3    Kizu, H.4    Okamoto, T.5    Asano, N.6    Adachi, I.7
  • 40
    • 84975156965 scopus 로고    scopus 로고
    • Agrimonia eupatoria L. and Cynara cardunculus L. Water infusions: Comparison of anti-diabetic activities
    • Kuczmannová, A., Balažová, A., Račanská, E., Kameníková, M., Fialová, S., Majerník, J., … Mučaji, P. (2016). Agrimonia eupatoria L. and Cynara cardunculus L. Water infusions: Comparison of anti-diabetic activities. Molecules, 21(5), 564. https://doi.org/10.3390/molecules21050564
    • (2016) Molecules , vol.21 , Issue.5 , pp. 564
    • Kuczmannová, A.1    Balažová, A.2    Račanská, E.3    Kameníková, M.4    Fialová, S.5    Majerník, J.6    Mučaji, P.7
  • 41
    • 81155144657 scopus 로고    scopus 로고
    • Antidiabetic activity of alcoholic leaves extract of Alangium lamarckii Thwaites on streptozotocin–nicotinamide induced type 2 diabetic rats
    • Kumar, R., Pate, D. K., Prasad, S. K., Sairam, K., & Hemalatha, S. (2011). Antidiabetic activity of alcoholic leaves extract of Alangium lamarckii Thwaites on streptozotocin–nicotinamide induced type 2 diabetic rats. Asian Pacific Journal of Tropical Medicine, 4(11), 904–909.
    • (2011) Asian Pacific Journal of Tropical Medicine , vol.4 , Issue.11 , pp. 904-909
    • Kumar, R.1    Pate, D.K.2    Prasad, S.K.3    Sairam, K.4    Hemalatha, S.5
  • 42
    • 80052454400 scopus 로고    scopus 로고
    • In vivo evalution of hypoglycemic activity of Aloe spp. and identification of its mode of action on GLUT-4 gene expression in vitro
    • Kumar, R., Sharma, B., Tomar, N. R., Roy, P., Gupta, A. K., & Kumar, A. (2011). In vivo evalution of hypoglycemic activity of Aloe spp. and identification of its mode of action on GLUT-4 gene expression in vitro. Applied Biochemistry and Biotechnology, 164(8), 1246–1256.
    • (2011) Applied Biochemistry and Biotechnology , vol.164 , Issue.8 , pp. 1246-1256
    • Kumar, R.1    Sharma, B.2    Tomar, N.R.3    Roy, P.4    Gupta, A.K.5    Kumar, A.6
  • 43
    • 84885538630 scopus 로고    scopus 로고
    • Umbelliferone β-D-galactopyranoside from Aegle marmelos (L.) corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity
    • Kumar, V., Ahmed, D., Verma, A., Anwar, F., Ali, M., & Mujeeb, M. (2013). Umbelliferone β-D-galactopyranoside from Aegle marmelos (L.) corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity. BMC Complementary and Alternative Medicine, 13(1), 273.
    • (2013) BMC Complementary and Alternative Medicine , vol.13 , Issue.1 , pp. 273
    • Kumar, V.1    Ahmed, D.2    Verma, A.3    Anwar, F.4    Ali, M.5    Mujeeb, M.6
  • 46
    • 16344380411 scopus 로고    scopus 로고
    • Cuminaldehyde: Aldose reductase and α-glucosidase inhibitor derived from Cuminum cyminum L. seeds
    • Lee, H.-S. (2005). Cuminaldehyde: Aldose reductase and α-glucosidase inhibitor derived from Cuminum cyminum L. seeds. Journal of Agricultural and Food Chemistry, 53(7), 2446–2450.
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , Issue.7 , pp. 2446-2450
    • Lee, H.-S.1
  • 47
    • 84903836554 scopus 로고    scopus 로고
    • The role of pyruvate dehydrogenase kinase in diabetes and obesity
    • Lee, I.-K. (2014). The role of pyruvate dehydrogenase kinase in diabetes and obesity. Diabetes & Metabolism Journal, 38(3), 181–186.
    • (2014) Diabetes & Metabolism Journal , vol.38 , Issue.3 , pp. 181-186
    • Lee, I.-K.1
  • 48
    • 84894045189 scopus 로고    scopus 로고
    • Antioxidant and α-glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants
    • Lee, S., Mediani, A., Nur Ashikin, A., Azliana, A., & Abas, F. (2014). Antioxidant and α-glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants. International Food Research Journal, 21(1).
    • (2014) International Food Research Journal , vol.21 , Issue.1
    • Lee, S.1    Mediani, A.2    Nur Ashikin, A.3    Azliana, A.4    Abas, F.5
  • 50
    • 19444377479 scopus 로고    scopus 로고
    • Punica granatum flower extract, a potent α-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats
    • Li, Y., Wen, S., Kota, B. P., Peng, G., Li, G. Q., Yamahara, J., & Roufogalis, B. D. (2005). Punica granatum flower extract, a potent α-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats. Journal of Ethnopharmacology, 99(2), 239–244. https://doi.org/10.1016/j.jep.2005.02.030
    • (2005) Journal of Ethnopharmacology , vol.99 , Issue.2 , pp. 239-244
    • Li, Y.1    Wen, S.2    Kota, B.P.3    Peng, G.4    Li, G.Q.5    Yamahara, J.6    Roufogalis, B.D.7
  • 51
    • 84882272020 scopus 로고    scopus 로고
    • Inhibition of pancreatic lipase, α-glucosidase, α-amylase, and hypolipidemic effects of the total flavonoids from Nelumbo nucifera leaves
    • Liu, S., Li, D., Huang, B., Chen, Y., Lu, X., & Wang, Y. (2013). Inhibition of pancreatic lipase, α-glucosidase, α-amylase, and hypolipidemic effects of the total flavonoids from Nelumbo nucifera leaves. Journal of Ethnopharmacology, 149(1), 263–269.
    • (2013) Journal of Ethnopharmacology , vol.149 , Issue.1 , pp. 263-269
    • Liu, S.1    Li, D.2    Huang, B.3    Chen, Y.4    Lu, X.5    Wang, Y.6
  • 52
    • 84936791941 scopus 로고    scopus 로고
    • Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles
    • Malapermal, V., Botha, I., Krishna, S. B. N., & Mbatha, J. N. (2017). Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles. Saudi Journal of Biological Sciences, 24(6), 1294–1305.
    • (2017) Saudi Journal of Biological Sciences , vol.24 , Issue.6 , pp. 1294-1305
    • Malapermal, V.1    Botha, I.2    Krishna, S.B.N.3    Mbatha, J.N.4
  • 53
    • 79959798614 scopus 로고    scopus 로고
    • Glucokinase activators for diabetes therapy: May 2010 status report
    • Matschinsky, F. M., Zelent, B., Doliba, N., Li, C., Vanderkooi, J. M., Naji, A., … Grimsby, J. (2011). Glucokinase activators for diabetes therapy: May 2010 status report. Diabetes Care, 34(Supplement 2), S236–S243. https://doi.org/10.2337/dc11-s236
    • (2011) Diabetes Care , vol.34 , pp. S236-S243
    • Matschinsky, F.M.1    Zelent, B.2    Doliba, N.3    Li, C.4    Vanderkooi, J.M.5    Naji, A.6    Grimsby, J.7
  • 54
    • 0034877810 scopus 로고    scopus 로고
    • α-Glucosidase inhibitory action of natural acylated anthocyanins. 2. α-Glucosidase inhibition by isolated acylated anthocyanins
    • Matsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., & Matsumoto, K. (2001). α-Glucosidase inhibitory action of natural acylated anthocyanins. 2. α-Glucosidase inhibition by isolated acylated anthocyanins. Journal of Agricultural and Food Chemistry, 49(4), 1952–1956.
    • (2001) Journal of Agricultural and Food Chemistry , vol.49 , Issue.4 , pp. 1952-1956
    • Matsui, T.1    Ueda, T.2    Oki, T.3    Sugita, K.4    Terahara, N.5    Matsumoto, K.6
  • 55
    • 84992741180 scopus 로고    scopus 로고
    • Evaluation of total flavonoids, myricetin, and quercetin from Hovenia dulcis Thunb. As inhibitors of α-amylase and α-glucosidase
    • Meng, Y., Su, A., Yuan, S., Zhao, H., Tan, S., Hu, C., … Guo, Y. (2016). Evaluation of total flavonoids, myricetin, and quercetin from Hovenia dulcis Thunb. As inhibitors of α-amylase and α-glucosidase. Plant Foods for Human Nutrition, 71(4), 444–449. https://doi.org/10.1007/s11130-016-0581-2
    • (2016) Plant Foods for Human Nutrition , vol.71 , Issue.4 , pp. 444-449
    • Meng, Y.1    Su, A.2    Yuan, S.3    Zhao, H.4    Tan, S.5    Hu, C.6    Guo, Y.7
  • 57
    • 85040688460 scopus 로고    scopus 로고
    • Antidiabetic and anti-obesity activity of Ficus carica: In vitro experimental studies
    • Mopuri, R., & Islam, M. S. (2016). Antidiabetic and anti-obesity activity of Ficus carica: In vitro experimental studies. Diabetes & Metabolism, 42(4), 300.
    • (2016) Diabetes & Metabolism , vol.42 , Issue.4 , pp. 300
    • Mopuri, R.1    Islam, M.S.2
  • 59
    • 85054421209 scopus 로고    scopus 로고
    • In vitro anti-diabetic activity of seed extracts of Cassia auriculata and Cassia angustifolia
    • Nanumala, S. K., Tulasi, P., & Sujitha, E. (2015). In vitro anti-diabetic activity of seed extracts of Cassia auriculata and Cassia angustifolia. European Journal of Experimental Biology, 5(5), 12–17.
    • (2015) European Journal of Experimental Biology , vol.5 , Issue.5 , pp. 12-17
    • Nanumala, S.K.1    Tulasi, P.2    Sujitha, E.3
  • 60
    • 84862748465 scopus 로고    scopus 로고
    • Evaluation of alpha amylase inhibitory potential of four traditional culinary leaves
    • Narkhede, M. B. (2012). Evaluation of alpha amylase inhibitory potential of four traditional culinary leaves. Asian Journal of Pharmaceutical and Clinical Research, 5(2), 75–76.
    • (2012) Asian Journal of Pharmaceutical and Clinical Research , vol.5 , Issue.2 , pp. 75-76
    • Narkhede, M.B.1
  • 61
    • 84865504857 scopus 로고    scopus 로고
    • α-Glucosidase inhibitory hydrolyzable tannins from Eugenia jambolana seeds
    • Omar, R., Li, L., Yuan, T., & Seeram, N. P. (2012). α-Glucosidase inhibitory hydrolyzable tannins from Eugenia jambolana seeds. Journal of Natural Products, 75(8), 1505–1509.
    • (2012) Journal of Natural Products , vol.75 , Issue.8 , pp. 1505-1509
    • Omar, R.1    Li, L.2    Yuan, T.3    Seeram, N.P.4
  • 62
    • 12444306435 scopus 로고    scopus 로고
    • Inhibition of α-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs
    • Önal, S., Timur, S., Okutucu, B., & Zihnioğlu, F. (2005). Inhibition of α-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. Preparative Biochemistry and Biotechnology, 35(1), 29–36.
    • (2005) Preparative Biochemistry and Biotechnology , vol.35 , Issue.1 , pp. 29-36
    • Önal, S.1    Timur, S.2    Okutucu, B.3    Zihnioğlu, F.4
  • 63
  • 64
    • 0034858930 scopus 로고    scopus 로고
    • α-Glucosidase inhibitory activity of Mangifera indica bark
    • Prashanth, D., Amit, A., Samiulla, D., Asha, M., & Padmaja, R. (2001). α-Glucosidase inhibitory activity of Mangifera indica bark. Fitoterapia, 72(6), 686–688.
    • (2001) Fitoterapia , vol.72 , Issue.6 , pp. 686-688
    • Prashanth, D.1    Amit, A.2    Samiulla, D.3    Asha, M.4    Padmaja, R.5
  • 66
    • 77949264278 scopus 로고    scopus 로고
    • Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America
    • Ranilla, L. G., Kwon, Y.-I., Apostolidis, E., & Shetty, K. (2010). Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresource Technology, 101(12), 4676–4689.
    • (2010) Bioresource Technology , vol.101 , Issue.12 , pp. 4676-4689
    • Ranilla, L.G.1    Kwon, Y.-I.2    Apostolidis, E.3    Shetty, K.4
  • 67
    • 85028870201 scopus 로고    scopus 로고
    • In vitro alpha-amylase and alpha-glucosidase inhibition activity of umbelliferone and beta-ionone isolated from Coriandrum sativum Linn
    • Rayar, A., & Manivannan, R. (2016). In vitro alpha-amylase and alpha-glucosidase inhibition activity of umbelliferone and beta-ionone isolated from Coriandrum sativum Linn. World Journal of Pharmacy and Pharmaceutical Sciences, 5(1), 1280–1289.
    • (2016) World Journal of Pharmacy and Pharmaceutical Sciences , vol.5 , Issue.1 , pp. 1280-1289
    • Rayar, A.1    Manivannan, R.2
  • 68
    • 84967094500 scopus 로고    scopus 로고
    • Evaluation of alpha-amylase and alpha-glucosidase inhibitory activities of Shilajit
    • Rege, A. A. A., & Chowdhary, A. S. (2014). Evaluation of alpha-amylase and alpha-glucosidase inhibitory activities of Shilajit. International Journal of Advanced Research, 2(2), 735–740.
    • (2014) International Journal of Advanced Research , vol.2 , Issue.2 , pp. 735-740
    • Rege, A.A.A.1    Chowdhary, A.S.2
  • 69
    • 85056265443 scopus 로고    scopus 로고
    • Inhibitory effect on α-glucosidase by traditional thai medicinal plants
    • Rungprom, W. (2014). Inhibitory effect on α-glucosidase by traditional thai medicinal plants. CURRENT APPLIED SCIENCE AND TECHNOLOGY Journal, 14(2).
    • (2014) CURRENT APPLIED SCIENCE AND TECHNOLOGY Journal , vol.14 , Issue.2
    • Rungprom, W.1
  • 70
    • 84892646595 scopus 로고    scopus 로고
    • Glucosidase and-amylase inhibitory effect and antioxidant activity of ten plant extracts traditionally used in Iran for diabetes
    • Salehi, P., Asghari, B., Esmaeili, M. A., Dehghan, H., & Ghazi, I. (2013). Glucosidase and-amylase inhibitory effect and antioxidant activity of ten plant extracts traditionally used in Iran for diabetes. Journal of Medicinal Plant Research, 7(6), 257–266.
    • (2013) Journal of Medicinal Plant Research , vol.7 , Issue.6 , pp. 257-266
    • Salehi, P.1    Asghari, B.2    Esmaeili, M.A.3    Dehghan, H.4    Ghazi, I.5
  • 72
    • 84904796777 scopus 로고    scopus 로고
    • Isolation and characterization of an α-glucosidase inhibitor from Musa spp.(Baxijiao) flowers
    • Sheng, Z., Dai, H., Pan, S., Wang, H., Hu, Y., & Ma, W. (2014). Isolation and characterization of an α-glucosidase inhibitor from Musa spp.(Baxijiao) flowers. Molecules, 19(7), 10563–10573.
    • (2014) Molecules , vol.19 , Issue.7 , pp. 10563-10573
    • Sheng, Z.1    Dai, H.2    Pan, S.3    Wang, H.4    Hu, Y.5    Ma, W.6
  • 73
    • 80051783296 scopus 로고    scopus 로고
    • Cinnamon extract inhibited the α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats
    • Shihabudeen, H. M. S., Priscilla, D. H., & Thirumurugan, K. (2011). Cinnamon extract inhibited the α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats. Nutrition and Metabolism, 8(1), 46.
    • (2011) Nutrition and Metabolism , vol.8 , Issue.1 , pp. 46
    • Shihabudeen, H.M.S.1    Priscilla, D.H.2    Thirumurugan, K.3
  • 74
    • 75149130512 scopus 로고    scopus 로고
    • The involvement of aldose reductase in alterations to neurotrophin receptors and neuronal cytoskeletal protein mRNA levels in the dorsal root ganglion of streptozotocin-induced diabetic rats
    • Shimoshige, Y., Enomoto, R., Aoki, T., Matsuoka, N., & Kaneko, S. (2010). The involvement of aldose reductase in alterations to neurotrophin receptors and neuronal cytoskeletal protein mRNA levels in the dorsal root ganglion of streptozotocin-induced diabetic rats. Biological and Pharmaceutical Bulletin, 33(1), 67–71.
    • (2010) Biological and Pharmaceutical Bulletin , vol.33 , Issue.1 , pp. 67-71
    • Shimoshige, Y.1    Enomoto, R.2    Aoki, T.3    Matsuoka, N.4    Kaneko, S.5
  • 76
    • 0035433418 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein
    • Slosberg, E. D., Desai, U. J., Fanelli, B., Denny, I. S., Connelly, S., Kaleko, M., … Caplan, S. L. (2001). Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein. Diabetes, 50(8), 1813–1820. https://doi.org/10.2337/diabetes.50.8.1813
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1813-1820
    • Slosberg, E.D.1    Desai, U.J.2    Fanelli, B.3    Denny, I.S.4    Connelly, S.5    Kaleko, M.6    Caplan, S.L.7
  • 78
    • 46749119448 scopus 로고    scopus 로고
    • In vitro α-glucosidase and α-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide
    • Subramanian, R., Asmawi, M. Z., & Sadikun, A. (2008). In vitro α-glucosidase and α-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. Acta Biochimica Polonica, 55(2), 391–398.
    • (2008) Acta Biochimica Polonica , vol.55 , Issue.2 , pp. 391-398
    • Subramanian, R.1    Asmawi, M.Z.2    Sadikun, A.3
  • 80
    • 2442700346 scopus 로고    scopus 로고
    • Inhibition of aldose reductase by tannoid principles of Emblica officinalis: Implications for the prevention of sugar cataract
    • Suryanarayana, P., Kumar, P. A., Saraswat, M., Petrash, J. M., & Reddy, G. B. (2004). Inhibition of aldose reductase by tannoid principles of Emblica officinalis: Implications for the prevention of sugar cataract. Molecular Vision, 10, 148–154.
    • (2004) Molecular Vision , vol.10 , pp. 148-154
    • Suryanarayana, P.1    Kumar, P.A.2    Saraswat, M.3    Petrash, J.M.4    Reddy, G.B.5
  • 82
    • 79959230834 scopus 로고    scopus 로고
    • A protein tyrosine phosphatase 1B activity inhibitor from the fruiting bodies of Ganoderma lucidum (Fr.) Karst and its hypoglycemic potency on streptozotocin-induced type 2 diabetic mice
    • Teng, B.-S., Wang, C.-D., Yang, H.-J., Wu, J.-S., Zhang, D., Zheng, M., … Zhou, P. (2011). A protein tyrosine phosphatase 1B activity inhibitor from the fruiting bodies of Ganoderma lucidum (Fr.) Karst and its hypoglycemic potency on streptozotocin-induced type 2 diabetic mice. Journal of Agricultural and Food Chemistry, 59(12), 6492–6500. https://doi.org/10.1021/jf200527y
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.12 , pp. 6492-6500
    • Teng, B.-S.1    Wang, C.-D.2    Yang, H.-J.3    Wu, J.-S.4    Zhang, D.5    Zheng, M.6    Zhou, P.7
  • 83
    • 84881624747 scopus 로고    scopus 로고
    • Advanced glycation end products
    • Karger Publishers
    • Thomas, M. C. (2011). Advanced glycation end products. In Diabetes and the kidney (pp. 66–74). Karger Publishers.
    • (2011) Diabetes and the kidney , pp. 66-74
    • Thomas, M.C.1
  • 84
    • 84883145038 scopus 로고    scopus 로고
    • Antidiabetic and antioxidant properties of alkaloids from catharanthus roseus (L.) G. Don
    • Tiong, S. H., Looi, C. Y., Hazni, H., Arya, A., Paydar, M., Wong, W. F., … Awang, K. (2013). Antidiabetic and antioxidant properties of alkaloids from catharanthus roseus (L.) G. Don. Molecules, 18(8), 9770–9784. https://doi.org/10.3390/molecules18089770
    • (2013) Molecules , vol.18 , Issue.8 , pp. 9770-9784
    • Tiong, S.H.1    Looi, C.Y.2    Hazni, H.3    Arya, A.4    Paydar, M.5    Wong, W.F.6    Awang, K.7
  • 85
    • 0027264057 scopus 로고
    • α-Glucosidase and aldose reductase inhibitors: Constituents of cashew, Anacardium occidentale, nut shell liquids
    • Toyomizu, M., Sugiyama, S., Jin, R., & Nakatsu, T. (1993). α-Glucosidase and aldose reductase inhibitors: Constituents of cashew, Anacardium occidentale, nut shell liquids. Phytotherapy Research, 7(3), 252–254.
    • (1993) Phytotherapy Research , vol.7 , Issue.3 , pp. 252-254
    • Toyomizu, M.1    Sugiyama, S.2    Jin, R.3    Nakatsu, T.4
  • 86
    • 85056254079 scopus 로고    scopus 로고
    • Ghyoot G (Eds.). (, IDF diabetes atlas, International Diabetes Federation
    • Unwin, N, Whiting, D, Gan, D, Jacqmain, O, Ghyoot G (Eds.). (2009). IDF diabetes atlas. International Diabetes Federation.
    • (2009)
    • Unwin, N.1    Whiting, D.2    Gan, D.3    Jacqmain, O.4
  • 87
    • 84873915077 scopus 로고    scopus 로고
    • Antidiabetic components of Cassia alata leaves: Identification through α-glucosidase inhibition studies
    • Varghese, G. K., Bose, L. V., & Habtemariam, S. (2013). Antidiabetic components of Cassia alata leaves: Identification through α-glucosidase inhibition studies. Pharmaceutical Biology, 51(3), 345–349.
    • (2013) Pharmaceutical Biology , vol.51 , Issue.3 , pp. 345-349
    • Varghese, G.K.1    Bose, L.V.2    Habtemariam, S.3
  • 88
    • 85015721031 scopus 로고    scopus 로고
    • Synergisms in alpha-glucosidase inhibition and antioxidant activity of Camellia sinensis L. Kuntze and Eugenia uniflora L. Ethanolic extracts
    • Vinholes, J., & Vizzotto, M. (2017). Synergisms in alpha-glucosidase inhibition and antioxidant activity of Camellia sinensis L. Kuntze and Eugenia uniflora L. Ethanolic extracts. Pharmacognosy Research, 9(1), 101.
    • (2017) Pharmacognosy Research , vol.9 , Issue.1 , pp. 101
    • Vinholes, J.1    Vizzotto, M.2
  • 89
    • 0036876073 scopus 로고    scopus 로고
    • Decreased blood activity of glucose-6-phosphate dehydrogenase associates with increased risk for diabetes mellitus
    • Wan, G.-H., Tsai, S.-C., & Chiu, D. T.-Y. (2002). Decreased blood activity of glucose-6-phosphate dehydrogenase associates with increased risk for diabetes mellitus. Endocrine, 19(2), 191–195.
    • (2002) Endocrine , vol.19 , Issue.2 , pp. 191-195
    • Wan, G.-H.1    Tsai, S.-C.2    Chiu, D.T.Y.3
  • 91
    • 85014186577 scopus 로고    scopus 로고
    • In vitro antidiabetic effects of selected fruits and vegetables against glycosidase and aldose reductase
    • Wu, T., Luo, J., & Xu, B. (2015). In vitro antidiabetic effects of selected fruits and vegetables against glycosidase and aldose reductase. Food Science & Nutrition, 3(6), 495–505.
    • (2015) Food Science & Nutrition , vol.3 , Issue.6 , pp. 495-505
    • Wu, T.1    Luo, J.2    Xu, B.3
  • 92
    • 80054892771 scopus 로고    scopus 로고
    • Bioassay-guided screening and isolation of α-glucosidase and tyrosinase inhibitors from leaves of Morus alba
    • Yang, Z., Wang, Y., Wang, Y., & Zhang, Y. (2012). Bioassay-guided screening and isolation of α-glucosidase and tyrosinase inhibitors from leaves of Morus alba. Food Chemistry, 131(2), 617–625.
    • (2012) Food Chemistry , vol.131 , Issue.2 , pp. 617-625
    • Yang, Z.1    Wang, Y.2    Wang, Y.3    Zhang, Y.4
  • 93
    • 84867358813 scopus 로고    scopus 로고
    • Link between the renin–angiotensin system and insulin resistance: Implications for cardiovascular disease
    • Zhou, M.-S., Schulman, I. H., & Zeng, Q. (2012). Link between the renin–angiotensin system and insulin resistance: Implications for cardiovascular disease. Vascular Medicine, 17(5), 330–341.
    • (2012) Vascular Medicine , vol.17 , Issue.5 , pp. 330-341
    • Zhou, M.-S.1    Schulman, I.H.2    Zeng, Q.3
  • 94
    • 84892585015 scopus 로고    scopus 로고
    • Aldose reductase inhibitors as potential therapeutic drugs of diabetic complications
    • InTech
    • Zhu, C. (2013). Aldose reductase inhibitors as potential therapeutic drugs of diabetic complications. In Diabetes mellitus-insights and perspectives. InTech.
    • (2013) Diabetes mellitus-insights and perspectives
    • Zhu, C.1


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