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Volumn 164, Issue 8, 2011, Pages 1246-1256

In vivo evalution of hypoglycemic activity of Aloe spp. and identification of its mode of Action on GLUT-4 gene expression in vitro

Author keywords

Aloe extract; Diabetes mellitus; Glucose tolerance test; GLUT 4 gene; Hexokinase assay; In vitro; In vivo; Lipid profile; NIH 3T3 cells

Indexed keywords

ALOE EXTRACT; DIABETES MELLITUS; GLUCOSE TOLERANCE TEST; GLUT-4 GENE; HEXOKINASES; IN VITRO; IN VIVO; LIPID PROFILE; NIH/3T3 CELLS;

EID: 80052454400     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-011-9210-6     Document Type: Article
Times cited : (38)

References (30)
  • 1
    • 0345699417 scopus 로고
    • Clinical correlates of metabolic derangements of diabetes mellitus
    • G. P. Kozak (Ed.), Philadelphia: W.B. Saunders
    • Arky, R. A. (1982). Clinical correlates of metabolic derangements of diabetes mellitus. In G. P. Kozak (Ed.), Complications of diabetes mellitus (pp. 16-20). Philadelphia: W.B. Saunders.
    • (1982) Complications of Diabetes Mellitus , pp. 16-20
    • Arky, R.A.1
  • 3
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes estimates for the year 2000 and projections for 2030
    • Wild, S., Roglie, G., Green, A., et al. (2004). Global prevalence of diabetes estimates for the year 2000 and projections for 2030. Diabetes Care, 27(5), 1047-1059.
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1059
    • Wild, S.1    Roglie, G.2    Green, A.3
  • 4
    • 0024330279 scopus 로고
    • Traditional plant medicine as treatment for diabetes
    • Bailey, L. J., & Day, C. (1989). Traditional plant medicine as treatment for diabetes. Diabetes Care, 12, 553-564.
    • (1989) Diabetes Care , vol.12 , pp. 553-564
    • Bailey, L.J.1    Day, C.2
  • 6
    • 0002249094 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus
    • Yongchaiyudha, S., Rungpitarangsi, V., Bunyapraphatsara, N., et al. (1996). Antidiabetic activity of Aloe vera juice l. Clinical trial in new cases of diabetes mellitus. Phytomedicine, 3, 241-243. (Pubitemid 126504564)
    • (1996) Phytomedicine , vol.3 , Issue.3 , pp. 241-243
    • Yongchaiyudha, S.1    Rungpitarangsi, V.2    Bunyapraphatsara, N.3    Chokechaijaroenporn, O.4
  • 7
    • 72549098607 scopus 로고    scopus 로고
    • Possible hypoglycemic effect of Aloe vera L. High molecular weight fractions on type 2 diabetic patients
    • Yagi, A., Hegazy, S., Kabbash, A., et al. (2009). Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients. Saudi Pharmaceutical Journal, 17(3), 210-217.
    • (2009) Saudi Pharmaceutical Journal , vol.17 , Issue.3 , pp. 210-217
    • Yagi, A.1    Hegazy, S.2    Kabbash, A.3
  • 8
    • 0025234740 scopus 로고
    • Effects of Aloes on blood glucose levels in normal and Alloxan-diabetic mice
    • Ajbanoor, M. A. (1990). Effects of Aloes on blood glucose levels in normal and Alloxan-diabetic mice. Journal of Ethnopharmacology, 28, 215-220.
    • (1990) Journal of Ethnopharmacology , vol.28 , pp. 215-220
    • Ajbanoor, M.A.1
  • 9
    • 0027462719 scopus 로고
    • Hypoglycaemic and antidiabetic effects in mice of Aloe arborescens Miller var. natalensis Berger
    • Beppu, H., Nagamura, Y., & Fujita, K. (1993). Hypoglycaemic and anti-diabetic effects in mice of Aloe arborescens Miller var. natalensis Berger. Phytotherapy Research, 7, S37-S42. (Pubitemid 23106496)
    • (1993) Phytotherapy Research , vol.7 , Issue.SPEC. ISS.
    • Beppu, H.1    Nagamura, Y.2    Fujita, K.3
  • 10
    • 31344476763 scopus 로고    scopus 로고
    • Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: Investigation on hypoglycemic action and systemic absorption dynamics of aloe components
    • DOI 10.1016/j.jep.2005.10.034, PII S0378874105007804
    • Beppu, H., Shimpo, K., Chihara, T., et al. (2006). Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice, investigation on hypoglycemic action and systemic absorption dynamics of Aloe components. Journal of Ethnopharmacology, 103, 468-477. (Pubitemid 43143385)
    • (2006) Journal of Ethnopharmacology , vol.103 , Issue.3 , pp. 468-477
    • Beppu, H.1    Shimpo, K.2    Chihara, T.3    Kaneko, T.4    Tamai, I.5    Yamaji, S.6    Ozaki, S.7    Kuzuya, H.8    Sonoda, S.9
  • 11
    • 1842423773 scopus 로고    scopus 로고
    • Hypoglycemic Effect of Aloe vera Gel on Streptozotocin-Induced Diabetes in Experimental Rats
    • DOI 10.1089/109662004322984725
    • Rajasekaran, S., Sivagnanam, K., Ravi, K., et al. (2004). Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. Journal of Medicinal Food, 7, 61-66. (Pubitemid 38445924)
    • (2004) Journal of Medicinal Food , vol.7 , Issue.1 , pp. 61-66
    • Rajasekaran, S.1    Sivagnanam, K.2    Ravi, K.3    Subramanian, S.4
  • 12
    • 12344264705 scopus 로고    scopus 로고
    • Modulatory effects of Aloe vera leaf gel extract on oxidative stress in rats treated with streptozotocin
    • DOI 10.1211/0022357055416
    • Rajasekaran, S., Sivagnanam, K., & Subramanian, S. (2005). Modulatory effects of Aloe vera leaf gel extract on oxidative stress in rats treated with streptozotocin. The Journal of Pharmacy and Pharmacology, 57, 241-246. (Pubitemid 40129093)
    • (2005) Journal of Pharmacy and Pharmacology , vol.57 , Issue.2 , pp. 241-246
    • Rajasekaran, S.1    Sivagnanam, K.2    Subramanian, S.3
  • 13
    • 33645054804 scopus 로고    scopus 로고
    • Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes
    • Rajasekaran, S., Ravi, K., Sivagnanam, K., et al. (2006). Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clinical and Experimental Pharmacology & Physiology, 33, 232-237.
    • (2006) Clinical and Experimental Pharmacology & Physiology , vol.33 , pp. 232-237
    • Rajasekaran, S.1    Ravi, K.2    Sivagnanam, K.3
  • 14
    • 67650568107 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus
    • Kim, K., Kim, H., Kwon, J., et al. (2009). Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine, 16, 856-863.
    • (2009) Phytomedicine , vol.16 , pp. 856-863
    • Kim, K.1    Kim, H.2    Kwon, J.3
  • 15
    • 58049103697 scopus 로고    scopus 로고
    • Inventry of antidiabetic plants in selected districts of lagos state, Nigeria
    • Gbolade, A. A. (2009). Inventry of antidiabetic plants in selected districts of lagos state, Nigeria. Journal of Ethnopharmacology, 121, 135-139.
    • (2009) Journal of Ethnopharmacology , vol.121 , pp. 135-139
    • Gbolade, A.A.1
  • 16
    • 0022469014 scopus 로고
    • The antidiabetic activity of aloes: Preliminary clinical and experimental observations
    • Ghannam, N., & Geissman, E. S. (1986). The anti-diabetic activity of Aloes, preliminary clinical and experimental observations. Hormone Research, 24, 288-294. (Pubitemid 16004133)
    • (1986) Hormone Research , vol.24 , Issue.4 , pp. 288-294
    • Ghannam, N.1    Kingston, M.2    Al-Meshaal, I.A.3
  • 17
    • 0037086660 scopus 로고    scopus 로고
    • The glucose-6-phosphatase system
    • DOI 10.1042/0264-6021:3620513
    • Schaftingen, E. V., & Gerin, I. (2002). The glucose-6-phosphatase system. Journal of Biochemistry, 362, 513-532. (Pubitemid 34242301)
    • (2002) Biochemical Journal , vol.362 , Issue.3 , pp. 513-532
    • Van Schaftingen, E.1    Gerin, I.2
  • 19
    • 1942518128 scopus 로고    scopus 로고
    • Carbohydrates
    • S. Sadasivam & A. Manickam (Eds.), New Delhi: New Age International Private Limited
    • Sadasivam, S., & Manickam, A. (1996). Carbohydrates. In S. Sadasivam & A. Manickam (Eds.), Methods in biochemistry (pp. 11-12). New Delhi: New Age International Private Limited.
    • (1996) Methods in Biochemistry , pp. 11-12
    • Sadasivam, S.1    Manickam, A.2
  • 20
    • 0027522910 scopus 로고
    • Mechanism of antiinflammatory and antithermal burn action of CPase from Aloe arborescens Miller var. natalensis Berger in rats and mice
    • Obata, M., Ito, S., & Beppu, H. (1993). Mechanism of antiinflammatory and antithermal burn action of Cpase from Aloe arborescence Miller var. natalensis berger in rats and mice. Phytotherapy Reasearch, 7 (7), S30-S33. (Pubitemid 23106494)
    • (1993) Phytotherapy Research , vol.7 , Issue.SPEC. ISS.
    • Obata, M.1    Ito, S.2    Beppu, H.3    Fujita, K.4    Nagatsu, T.5
  • 21
    • 50949107303 scopus 로고    scopus 로고
    • Composition and applications of Aloe vera gel
    • Hamman, J. H. (2008). Composition and applications of Aloe vera gel. Molecules, 13, 1599-1616.
    • (2008) Molecules , vol.13 , pp. 1599-1616
    • Hamman, J.H.1
  • 22
    • 77952094084 scopus 로고    scopus 로고
    • The use of metformin in type 1 diabetes: A systemic review of efficacy
    • Vella, S., Buetlow, L., Royle, P., et al. (2010). The use of metformin in type 1 diabetes: a systemic review of efficacy. Diabetologia, 53(5), 809-820.
    • (2010) Diabetologia , vol.53 , Issue.5 , pp. 809-820
    • Vella, S.1    Buetlow, L.2    Royle, P.3
  • 23
    • 34548284906 scopus 로고    scopus 로고
    • The Rationale for Prandial Glycemic Control in Diabetes Mellitus
    • DOI 10.1016/S1557-0843(07)80016-9, PII S1557084307800169
    • Perkins, J. M., & Davis, S. N. (2007). The rationale for prandial glycemic control in diabetes mellitus. Insulin, 2(2), 52-60. (Pubitemid 47324331)
    • (2007) Insulin , vol.2 , Issue.2 , pp. 52-60
    • Perkins, J.M.1    Davis, S.N.2
  • 24
    • 75049084201 scopus 로고    scopus 로고
    • Postprandial apolipopreotein B48 is associated with asymptomatic peripheral arterial diseases, a study in patients with type 2 diabetes and controls
    • Valdivielso, P., Puerta, S., Rioja, J., et al. (2010). Postprandial apolipopreotein B48 is associated with asymptomatic peripheral arterial diseases, a study in patients with type 2 diabetes and controls. Clinica Chimica Acta, 411, 433-437.
    • (2010) Clinica Chimica Acta , vol.411 , pp. 433-437
    • Valdivielso, P.1    Puerta, S.2    Rioja, J.3
  • 26
    • 0028152377 scopus 로고
    • Facilitative glucose transporters
    • Mueckler, M. (1994). Facilitative glucose transporters. European Journal of Biochemistry, 219, 713-725. (Pubitemid 24050938)
    • (1994) European Journal of Biochemistry , vol.219 , Issue.3 , pp. 713-725
    • Mueckler, M.1
  • 27
    • 0026801474 scopus 로고
    • Cellular mechanism of Metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscles cells
    • Hundal, H. S., Ramlal, T., Reyes, R., et al. (1992). Cellular mechanism of Metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscles cells. Endocrinology, 131, 1165-1173.
    • (1992) Endocrinology , vol.131 , pp. 1165-1173
    • Hundal, H.S.1    Ramlal, T.2    Reyes, R.3
  • 28
    • 0028129862 scopus 로고
    • Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM
    • DOI 10.1007/s001250050184
    • Galuska, D., Nolte, L. A., Zierath, J. R., et al. (1994). Effects of Metformin on insulin-stimulated glucose transport in isolated skeletal muscles obtained from patients with NIDDM. Diabetologia, 37, 826-832. (Pubitemid 24247854)
    • (1994) Diabetologia , vol.37 , Issue.8 , pp. 826-832
    • Galuska, D.1    Nolte, L.A.2    Zierath, J.R.3    Wallberg-Henriksson, H.4
  • 29
    • 18144436363 scopus 로고    scopus 로고
    • Reducing insulin resistance with metformin, the evidence today
    • Giannarelli, R., Aragona, M., Coppelli, A., et al. (2003). Reducing insulin resistance with metformin, the evidence today. Diabetes & Metabolism, 29, S628-S635.
    • (2003) Diabetes & Metabolism , vol.29
    • Giannarelli, R.1    Aragona, M.2    Coppelli, A.3


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