Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice

Diabetes

Volumn 52, Issue 1, 2003, Pages 21-28

  Gum, Rebecca J ^a   Gaede, Lori L ^a   Koterski, Sandra L ^a   Heindel, Matthew ^a   Clampit, Jill E ^a   Zinker, Bradley A ^a   Trevillyan, James M ^a   Ulrich, Roger G ^a   Jirousek, Michael R ^a   Rondinone, Cristina M ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESPONSE; INSULIN SENSITIVITY; LIVER; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPECIES COMPARISON;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; GLYCOGEN SYNTHASE KINASE 3; INSULIN; LIVER; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OBESITY; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SERINE; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0037221179     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.1.21     Document Type: Article

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