Diaphragm Weakness in the Critically Ill: Basic Mechanisms Reveal Therapeutic Opportunities

Chest

Volumn 154, Issue 6, 2018, Pages 1395-1403

  Petrof, Basil J ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

critical illness myopathy; diaphragm disuse; ICU acquired weakness; mechanical ventilation; sepsis; ventilator induced diaphragm dysfunction; weaning failure

Indexed keywords

2,3,4,5 TETRAHYDRO 7 METHOXY 4 METHYL 1,4 BENZOTHIAZEPINE; ACETYLCYSTEINE; ALPHA TOCOPHEROL; BORTEZOMIB; CALPAIN; CASPASE 3; CATHEPSIN; CDIBA; CK 2066260; CURCUMIN; CYTOKINE; EDASALONEXENT; ELAMIPRETIDE; ERITORAN; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; LEUPEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYOSIN; O (2 HYDROXY 3 PIPERIDINOPROPYL)NICOTINIC AMIDOXIME; PROTEASOME; R 545; R 548; REACTIVE OXYGEN METABOLITE; RUXOLITINIB; RYANODINE RECEPTOR; SILTUXIMAB; SN 50; SUPEROXIDE; TOCILIZUMAB; TOLL LIKE RECEPTOR 4; TROPONIN; TUMOR NECROSIS FACTOR; UNINDEXED DRUG;

ARTIFICIAL VENTILATION; CRITICALLY ILL PATIENT; DIAPHRAGM DISEASE; HUMAN; INFLAMMATION; METABOLIC DISORDER; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; REVIEW; SEPSIS; VENTILATOR WEANING; ADVERSE EVENT; COMPLICATION; CRITICAL ILLNESS; DIAPHRAGM PARALYSIS; PATHOPHYSIOLOGY; PATIENT CARE; PROCEDURES;

CRITICAL ILLNESS; HUMANS; PATIENT CARE MANAGEMENT; RESPIRATION, ARTIFICIAL; RESPIRATORY PARALYSIS; SEPSIS;

EID: 85055909684     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2018.08.1028     Document Type: Review

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