Smad3 initiates oxidative stress and proteolysis that underlies diaphragm dysfunction during mechanical ventilation

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Tang, Huibin ^a,b   Kennedy, Catherine L ^a,b,d   Lee, Myung ^a,b   Gao, Yang ^a,b   Xia, Hui ^a,b,e   Olguin, Francesca ^a,b   Fraga, Danielle A ^a,b   Ayers, Kelsey ^a   Choi, Sehoon ^a,b,f   Kim, Michael ^a,b   Tehrani, Amir ^c   Sowb, Yasser A ^c   Rando, Thomas A ^a,b   Shrager, Joseph B ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c Respiratory Management Technologies LLC   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e CHINESE PLA GENERAL HOSPITAL   (China)

^f Asan Medical Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

MADH3 PROTEIN, RAT; SMAD3 PROTEIN;

ANIMAL; ARTIFICIAL VENTILATION; CELL CULTURE; DIAPHRAGM; FLOW CYTOMETRY; MALE; METABOLISM; MUSCLE ISOMETRIC CONTRACTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DIAPHRAGM; FLOW CYTOMETRY; ISOMETRIC CONTRACTION; MALE; OXIDATIVE STRESS; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; SMAD3 PROTEIN;

EID: 85033490366     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-11978-4     Document Type: Article

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