Intrinsic apoptosis in mechanically ventilated human diaphragm: Linkage to a novel Fos/FoxO1/Stat3-Bim axis

FASEB Journal

Volumn 25, Issue 9, 2011, Pages 2921-2936

  Tang, Huibin ^a,b   Lee, Myung ^a,b   Budak, Murat T ^c,d   Pietras, Nicole ^a,b   Hittinger, Scott ^a,b   Vu, Michael ^a,b   Khuong, Andy ^a,b   Hoang, Chuong D ^a,b   Hussain, Sabah N A ^e   Levine, Sanford ^c,d   Shrager, Joseph B ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Atrophy; Dysfunction; Oxidative stress; Respiratory muscle; Skeletal muscle

Indexed keywords

ACTIN; ATROGIN 1; BIM PROTEIN; CASPASE 3; CASPASE 9; CYTOCHROME C OXIDASE; FREE RADICAL; HYDROGEN PEROXIDE; REGULATOR PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOS; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; APOPTOSIS; ARTERIAL GAS; ARTICLE; ARTIFICIAL VENTILATION; CELL DEATH; CONTROLLED STUDY; DIAPHRAGM DISEASE; DIAPHRAGM MUSCLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MITOCHONDRIAL GENE; MUSCLE ATROPHY; MUSCLE CELL; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; VENTILATOR INDUCED DIAPHRAGM DYSFUNCTION;

ADOLESCENT; ADULT; AGED; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 9; CELL LINE; DIAPHRAGM; DNA FRAGMENTATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MITOCHONDRIA, MUSCLE; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; RESPIRATION, ARTIFICIAL; STAT3 TRANSCRIPTION FACTOR; YOUNG ADULT;

EID: 80052679510     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-183798     Document Type: Article

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