Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm

Journal of Applied Physiology

Volumn 118, Issue 9, 2015, Pages 1161-1171

  Picard, Martin ^a   Azuelos, Ilan ^b,d   Jung, Boris ^b,c   Giordano, Christian ^b   Matecki, Stefan ^c   Hussain, Sabah ^b,d   White, Kathryn ^e   Li, Tong ^b   Liang, Feng ^b   Benedetti, Andrea ^f   Gentil, Benoit J ^g   Burelle, Yan ^h   Petrof, Basil J ^a,b,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c HÔPITAL SAINT ELOI   (France)

^d MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

^f MCGILL UNIVERSITY   (Canada)

^g MCGILL UNIVERSITY   (Canada)

^h UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Electron microscopy; Intermyofibrillar mitochondria; Mitochondrial dynamics; Mitochondrial fragmentation; Subsarcolemmal mitochondria; Ventilator induced diaphragmatic dysfunction

Indexed keywords

DNM1L PROTEIN, MOUSE; DYNAMIN;

ANIMAL; ARTIFICIAL VENTILATION; C57BL MOUSE; DIAPHRAGM; MALE; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; MUSCLE ATROPHY; MUSCLE CONTRACTION; MUSCLE MITOCHONDRION; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SKELETAL MUSCLE;

ANIMALS; DIAPHRAGM; DYNAMINS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL DYNAMICS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUSCULAR ATROPHY; RESPIRATION, ARTIFICIAL;

EID: 84929333887     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00873.2014     Document Type: Article

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