Cross-talk between the calpain and caspase-3 proteolytic systems in the diaphragm during prolonged mechanical ventilation

Critical Care Medicine

Volumn 40, Issue 6, 2012, Pages 1857-1863

  Nelson, W Bradley ^a   Smuder, Ashley J ^a   Hudson, Matthew B ^a   Talbert, Erin E ^a   Powers, Scott K ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

atrophy; calpain; caspase 3; diaphragm; mechanical ventilation; skeletal muscle

Indexed keywords

CALPAIN; CALPASTATIN; CASPASE 12; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 9; PROTEIN BID; SJA 6017; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DIAPHRAGM MUSCLE ATROPHY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR INTERACTION; MUSCLE ATROPHY; NONHUMAN; PRIORITY JOURNAL; PROLONGED MECHANICAL VENTILATION; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; RAT; WESTERN BLOTTING;

ANIMALS; CALPAIN; CASPASE 3; DIAPHRAGM; ENZYME ACTIVATION; FEMALE; MUSCULAR ATROPHY; PROTEOLYSIS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84861528128     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318246bb5d     Document Type: Article

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