메뉴 건너뛰기




Volumn 42, Issue 12, 2014, Pages e772-e782

Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats

Author keywords

Autophagy; Contractile function; Cytokines; Oxidative stress; Proteolysis; Skeletal muscle

Indexed keywords

20S PROTEASOME ALPHA SUBUNIT; ATROGIN 1; BECLIN 1; CALPAIN; CASPASE 3; E2 CONJUGASE; ENZYME; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGASE; MUSCLE RING FINGER 1 PROTEIN; NORADRENALIN; PARKIN; PROTEASOME; PROTEIN BNIP3; PROTEOME; SODIUM CHLORIDE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYTOKINE; LIPOPOLYSACCHARIDE;

EID: 84922519297     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000685     Document Type: Article
Times cited : (52)

References (57)
  • 1
    • 0034524327 scopus 로고    scopus 로고
    • Muscular contractile failure in septic patients: Role of the inducible nitric oxide synthase pathway
    • Lanone S, Mebazaa A, Heymes C, et al: Muscular contractile failure in septic patients: Role of the inducible nitric oxide synthase pathway. Am J Respir Crit Care Med 2000;162:2308-2315
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 2308-2315
    • Lanone, S.1    Mebazaa, A.2    Heymes, C.3
  • 2
    • 0029797602 scopus 로고    scopus 로고
    • Induction of diaphragmatic nitric oxide synthase after endotoxin administration in rats: Role on diaphragmatic contractile dysfunction
    • Boczkowski J, Lanone S, Ungureanu-Longrois D, et al: Induction of diaphragmatic nitric oxide synthase after endotoxin administration in rats: Role on diaphragmatic contractile dysfunction. J Clin Invest 1996;98:1550-1559
    • (1996) J Clin Invest , vol.98 , pp. 1550-1559
    • Boczkowski, J.1    Lanone, S.2    Ungureanu-Longrois, D.3
  • 3
    • 0035125437 scopus 로고    scopus 로고
    • Free radical-induced contractile protein dysfunction in endotoxin-induced sepsis
    • Callahan LA, Nethery D, Stofan D, et al: Free radical-induced contractile protein dysfunction in endotoxin-induced sepsis. Am J Respir Cell Mol Biol 2001;24:210-217
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 210-217
    • Callahan, L.A.1    Nethery, D.2    Stofan, D.3
  • 4
    • 25444517270 scopus 로고    scopus 로고
    • Sepsis induces diaphragm electron transport chain dysfunction and protein depletion
    • Callahan LA, Supinski GS: Sepsis induces diaphragm electron transport chain dysfunction and protein depletion. Am J Respir Crit Care Med 2005;172:861-868
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 861-868
    • Callahan, L.A.1    Supinski, G.S.2
  • 5
    • 84867320566 scopus 로고    scopus 로고
    • Autophagy and skeletal muscles in sepsis
    • Mofarrahi M, Sigala I, Guo Y, et al: Autophagy and skeletal muscles in sepsis. PLoS One 2012;7:e47265
    • (2012) PLoS One , vol.7 , pp. e47265
    • Mofarrahi, M.1    Sigala, I.2    Guo, Y.3
  • 6
    • 73949117711 scopus 로고    scopus 로고
    • Calpain activation contributes to endotoxininduced diaphragmatic dysfunction
    • Supinski GS, Callahan LA: Calpain activation contributes to endotoxininduced diaphragmatic dysfunction. Am J Respir Cell Mol Biol 2010;42:80-87
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 80-87
    • Supinski, G.S.1    Callahan, L.A.2
  • 7
    • 33744926902 scopus 로고    scopus 로고
    • Caspase activation contributes to endotoxininduced diaphragm weakness
    • Supinski GS, Callahan LA: Caspase activation contributes to endotoxininduced diaphragm weakness. J Appl Physiol (1985) 2006;100:1770-1777
    • (2006) J Appl Physiol (1985) , vol.100 , pp. 1770-1777
    • Supinski, G.S.1    Callahan, L.A.2
  • 9
    • 0038292992 scopus 로고    scopus 로고
    • Detrimental effects of short-term mechanical ventilation on diaphragm function and IGF-I mRNA in rats
    • Gayan-Ramirez G, de Paepe K, Cadot P, et al: Detrimental effects of short-term mechanical ventilation on diaphragm function and IGF-I mRNA in rats. Intensive Care Med 2003;29:825-833
    • (2003) Intensive Care Med , vol.29 , pp. 825-833
    • Gayan-Ramirez, G.1    De Paepe, K.2    Cadot, P.3
  • 10
    • 0036084988 scopus 로고    scopus 로고
    • Mechanical ventilation results in progressive contractile dysfunction in the diaphragm
    • Powers SK, Shanely RA, Coombes JS, et al: Mechanical ventilation results in progressive contractile dysfunction in the diaphragm. J Appl Physiol (1985) 2002;92:1851-1858
    • (2002) J Appl Physiol (1985) , vol.92 , pp. 1851-1858
    • Powers, S.K.1    Shanely, R.A.2    Coombes, J.S.3
  • 11
    • 0036082131 scopus 로고    scopus 로고
    • Altered diaphragm contractile properties with controlled mechanical ventilation
    • Sassoon CS, Caiozzo VJ, Manka A, et al: Altered diaphragm contractile properties with controlled mechanical ventilation. J Appl Physiol (1985) 2002;92:2585-2595
    • (2002) J Appl Physiol (1985) , vol.92 , pp. 2585-2595
    • Sassoon, C.S.1    Caiozzo, V.J.2    Manka, A.3
  • 12
    • 41449113183 scopus 로고    scopus 로고
    • Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans
    • Levine S, Nguyen T, Taylor N, et al: Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 2008;358:1327-1335
    • (2008) N Engl J Med , vol.358 , pp. 1327-1335
    • Levine, S.1    Nguyen, T.2    Taylor, N.3
  • 13
    • 79951823621 scopus 로고    scopus 로고
    • Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse
    • Levine S, Biswas C, Dierov J, et al: Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse. Am J Respir Crit Care Med 2011;183:483-490
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 483-490
    • Levine, S.1    Biswas, C.2    Dierov, J.3
  • 14
    • 0037111133 scopus 로고    scopus 로고
    • Mechanical ventilationinduced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity
    • Shanely RA, Zergeroglu MA, Lennon SL, et al: Mechanical ventilationinduced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity. Am J Respir Crit Care Med 2002;166:1369-1374
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1369-1374
    • Shanely, R.A.1    Zergeroglu, M.A.2    Lennon, S.L.3
  • 15
  • 16
    • 9644284332 scopus 로고    scopus 로고
    • Trolox attenuates mechanical ventilation-induced diaphragmatic dysfunction and proteolysis
    • Betters JL, Criswell DS, Shanely RA, et al: Trolox attenuates mechanical ventilation-induced diaphragmatic dysfunction and proteolysis. Am J Respir Crit Care Med 2004;170:1179-1184
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1179-1184
    • Betters, J.L.1    Criswell, D.S.2    Shanely, R.A.3
  • 17
    • 33747601663 scopus 로고    scopus 로고
    • Mechanical ventilation promotes redox status alterations in the diaphragm
    • Falk DJ, Deruisseau KC, Van Gammeren DL, et al: Mechanical ventilation promotes redox status alterations in the diaphragm. J Appl Physiol (1985) 2006;101:1017-1024
    • (2006) J Appl Physiol (1985) , vol.101 , pp. 1017-1024
    • Falk, D.J.1    Deruisseau, K.C.2    Van Gammeren, D.L.3
  • 18
    • 78649821253 scopus 로고    scopus 로고
    • Mechanical ventilationinduced diaphragm disuse in humans triggers autophagy
    • Hussain SN, Mofarrahi M, Sigala I, et al: Mechanical ventilationinduced diaphragm disuse in humans triggers autophagy. Am J Respir Crit Care Med 2010;182:1377-1386
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1377-1386
    • Hussain, S.N.1    Mofarrahi, M.2    Sigala, I.3
  • 19
    • 0030852932 scopus 로고    scopus 로고
    • The effect of sepsis on breathing pattern and weaning outcomes in patients recovering from respiratory failure
    • Amoateng-Adjepong Y, Jacob BK, Ahmad M, et al: The effect of sepsis on breathing pattern and weaning outcomes in patients recovering from respiratory failure. Chest 1997;112:472-477
    • (1997) Chest , vol.112 , pp. 472-477
    • Amoateng-Adjepong, Y.1    Jacob, B.K.2    Ahmad, M.3
  • 20
    • 84881157964 scopus 로고    scopus 로고
    • Diaphragm dysfunction on admission to the intensive care unit. Prevalence, risk factors, and prognostic impact-a prospective study
    • Demoule A, Jung B, Prodanovic H, et al: Diaphragm dysfunction on admission to the intensive care unit. Prevalence, risk factors, and prognostic impact-a prospective study. Am J Respir Crit Care Med 2013;188:213-219
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 213-219
    • Demoule, A.1    Jung, B.2    Prodanovic, H.3
  • 21
    • 84879077910 scopus 로고    scopus 로고
    • Diaphragm weakness in mechanically ventilated critically ill patients
    • Supinski GS, Callahan LA: Diaphragm weakness in mechanically ventilated critically ill patients. Crit Care 2013;17:R120
    • (2013) Crit Care , vol.17 , pp. R120
    • Supinski, G.S.1    Callahan, L.A.2
  • 22
    • 0037080717 scopus 로고    scopus 로고
    • Mechanical ventilation protects against diaphragm injury in sepsis: Interaction of oxidative and mechanical stresses
    • Ebihara S, Hussain SN, Danialou G, et al: Mechanical ventilation protects against diaphragm injury in sepsis: Interaction of oxidative and mechanical stresses. Am J Respir Crit Care Med 2002;165:221-228
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 221-228
    • Ebihara, S.1    Hussain, S.N.2    Danialou, G.3
  • 23
    • 72749123964 scopus 로고    scopus 로고
    • Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness
    • Supinski GS, Wang W, Callahan LA: Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness. J Appl Physiol (1985) 2009;107:1389-1396
    • (2009) J Appl Physiol (1985) , vol.107 , pp. 1389-1396
    • Supinski, G.S.1    Wang, W.2    Callahan, L.A.3
  • 24
    • 29144479229 scopus 로고    scopus 로고
    • Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects
    • Gayan-Ramirez G, Testelmans D, Maes K, et al: Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects. Crit Care Med 2005;33:2804-2809
    • (2005) Crit Care Med , vol.33 , pp. 2804-2809
    • Gayan-Ramirez, G.1    Testelmans, D.2    Maes, K.3
  • 25
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim J, Kundu M, Viollet B, et al: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011;13:132-141
    • (2011) Nat Cell Biol , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3
  • 26
    • 36448940798 scopus 로고    scopus 로고
    • FoxO3 controls autophagy in skeletal muscle in vivo
    • Mammucari C, Milan G, Romanello V, et al: FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007;6:458-471
    • (2007) Cell Metab , vol.6 , pp. 458-471
    • Mammucari, C.1    Milan, G.2    Romanello, V.3
  • 27
    • 79251587803 scopus 로고    scopus 로고
    • Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
    • Egan DF, Shackelford DB, Mihaylova MM, et al: Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011;331:456-461
    • (2011) Science , vol.331 , pp. 456-461
    • Egan, D.F.1    Shackelford, D.B.2    Mihaylova, M.M.3
  • 28
    • 79958786699 scopus 로고    scopus 로고
    • Diaphragm muscle weakness in an experimental porcine intensive care unit model
    • Ochala J, Renaud G, Llano Diez M, et al: Diaphragm muscle weakness in an experimental porcine intensive care unit model. PLoS One 2011;6:e20558
    • (2011) PLoS One , vol.6 , pp. e20558
    • Ochala, J.1    Renaud, G.2    Llano Diez, M.3
  • 30
    • 0021134389 scopus 로고
    • Effect of lipopolysaccharide (from Escherichia coli) on the hepatic drug-metabolizing activities in successively LPS-treated mice
    • Sasaki K, Ishikawa-Saitoh M, Takayanagi G: Effect of lipopolysaccharide (from Escherichia coli) on the hepatic drug-metabolizing activities in successively LPS-treated mice. Jpn J Pharmacol 1984;34:241-248
    • (1984) Jpn J Pharmacol , vol.34 , pp. 241-248
    • Sasaki, K.1    Ishikawa-Saitoh, M.2    Takayanagi, G.3
  • 31
    • 13244288781 scopus 로고    scopus 로고
    • The šgcytokine profilešh: A code for sepsis
    • Ulloa L, Tracey KJ: The šgcytokine profilešh: A code for sepsis. Trends Mol Med 2005;11:56-63
    • (2005) Trends Mol Med , vol.11 , pp. 56-63
    • Ulloa, L.1    Tracey, K.J.2
  • 32
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen J: The immunopathogenesis of sepsis. Nature 2002;420:885-891
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 33
    • 4143125410 scopus 로고    scopus 로고
    • Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin
    • Altemeier WA, Matute-Bello G, Frevert CW, et al: Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin. Am J Physiol Lung Cell Mol Physiol 2004;287:L533-L542
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , pp. L533-L542
    • Altemeier, W.A.1    Matute-Bello, G.2    Frevert, C.W.3
  • 34
    • 59849123303 scopus 로고    scopus 로고
    • Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc (Min/+) mouse
    • Baltgalvis KA, Berger FG, Pena MM, et al: Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc (Min/+) mouse. Pflugers Arch 2009;457:989-1001
    • (2009) Pflugers Arch , vol.457 , pp. 989-1001
    • Baltgalvis, K.A.1    Berger, F.G.2    Pena, M.M.3
  • 35
    • 80053172499 scopus 로고    scopus 로고
    • Plasma from septic shock patients induces loss of muscle protein
    • van Hees HW, Schellekens WJ, Linkels M, et al: Plasma from septic shock patients induces loss of muscle protein. Crit Care 2011;15:R233
    • (2011) Crit Care , vol.15 , pp. R233
    • Van Hees, H.W.1    Schellekens, W.J.2    Linkels, M.3
  • 36
    • 62149083382 scopus 로고    scopus 로고
    • IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting
    • Zhang L, Du J, Hu Z, et al: IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting. J Am Soc Nephrol 2009;20:604-612
    • (2009) J Am Soc Nephrol , vol.20 , pp. 604-612
    • Zhang, L.1    Du, J.2    Hu, Z.3
  • 37
    • 84883485261 scopus 로고    scopus 로고
    • Stat3 activation links a C/EBPδ to myostatin pathway to stimulate loss of muscle mass
    • Zhang L, Pan J, Dong Y, et al: Stat3 activation links a C/EBPδ to myostatin pathway to stimulate loss of muscle mass. Cell Metab 2013;18:368-379
    • (2013) Cell Metab , vol.18 , pp. 368-379
    • Zhang, L.1    Pan, J.2    Dong, Y.3
  • 38
    • 0029975877 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum
    • Kumar A, Thota V, Dee L, et al: Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 1996;183:949-958
    • (1996) J Exp Med , vol.183 , pp. 949-958
    • Kumar, A.1    Thota, V.2    Dee, L.3
  • 39
    • 0027973469 scopus 로고
    • Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle
    • Tiao G, Fagan JM, Samuels N, et al: Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle. J Clin Invest 1994;94:2255-2264
    • (1994) J Clin Invest , vol.94 , pp. 2255-2264
    • Tiao, G.1    Fagan, J.M.2    Samuels, N.3
  • 40
    • 45149131614 scopus 로고    scopus 로고
    • Effects of chronic sepsis on contractile properties of fast twitch muscle in an experimental model of critical illness neuromyopathy in the rat
    • Rossignol B, Gueret G, Pennec JP, et al: Effects of chronic sepsis on contractile properties of fast twitch muscle in an experimental model of critical illness neuromyopathy in the rat. Crit Care Med 2008;36:1855-1863
    • (2008) Crit Care Med , vol.36 , pp. 1855-1863
    • Rossignol, B.1    Gueret, G.2    Pennec, J.P.3
  • 41
    • 0038806268 scopus 로고    scopus 로고
    • Role of ubiquitin-proteasome pathway in skeletal muscle wasting in rats with endotoxemia
    • Chai J, Wu Y, Sheng ZZ: Role of ubiquitin-proteasome pathway in skeletal muscle wasting in rats with endotoxemia. Crit Care Med 2003;31:1802-1807
    • (2003) Crit Care Med , vol.31 , pp. 1802-1807
    • Chai, J.1    Wu, Y.2    Sheng, Z.Z.3
  • 42
    • 0032846633 scopus 로고    scopus 로고
    • Endogenous peroxynitrite mediates mitochondrial dysfunction in rat diaphragm during endotoxemia
    • Boczkowski J, Lisdero CL, Lanone S, et al: Endogenous peroxynitrite mediates mitochondrial dysfunction in rat diaphragm during endotoxemia. FASEB J 1999;13:1637-1646
    • (1999) FASEB J , vol.13 , pp. 1637-1646
    • Boczkowski, J.1    Lisdero, C.L.2    Lanone, S.3
  • 43
    • 58149218633 scopus 로고    scopus 로고
    • Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure
    • Fredriksson K, Tjader I, Keller P, et al: Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure. PLoS One 2008;3:e3686
    • (2008) PLoS One , vol.3 , pp. e3686
    • Fredriksson, K.1    Tjader, I.2    Keller, P.3
  • 44
    • 78649905092 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and fragmentation as regulators of muscle protein degradation
    • Romanello V, Sandri M: Mitochondrial biogenesis and fragmentation as regulators of muscle protein degradation. Curr Hypertens Rep 2010;12:433-439
    • (2010) Curr Hypertens Rep , vol.12 , pp. 433-439
    • Romanello, V.1    Sandri, M.2
  • 45
    • 70449927247 scopus 로고    scopus 로고
    • Autophagy is required to maintain muscle mass
    • Masiero E, Agatea L, Mammucari C, et al: Autophagy is required to maintain muscle mass. Cell Metab 2009;10:507-515
    • (2009) Cell Metab , vol.10 , pp. 507-515
    • Masiero, E.1    Agatea, L.2    Mammucari, C.3
  • 46
    • 77950479450 scopus 로고    scopus 로고
    • Autophagy in skeletal muscle
    • Sandri M: Autophagy in skeletal muscle. FEBS Lett 2010;584:1411-1416
    • (2010) FEBS Lett , vol.584 , pp. 1411-1416
    • Sandri, M.1
  • 47
    • 84885071396 scopus 로고    scopus 로고
    • Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: A subanalysis of the EPaNIC trial
    • Hermans G, Casaer MP, Clerckx B, et al: Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: A subanalysis of the EPaNIC trial. Lancet Respir Med 2013;1:621-629
    • (2013) Lancet Respir Med , vol.1 , pp. 621-629
    • Hermans, G.1    Casaer, M.P.2    Clerckx, B.3
  • 48
    • 54849404282 scopus 로고    scopus 로고
    • Skeletal muscle is a primary target of SOD1G93A-mediated toxicity
    • Dobrowolny G, Aucello M, Rizzuto E, et al: Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab 2008;8:425-436
    • (2008) Cell Metab , vol.8 , pp. 425-436
    • Dobrowolny, G.1    Aucello, M.2    Rizzuto, E.3
  • 49
    • 77952586060 scopus 로고    scopus 로고
    • Mitochondrial fission and remodelling contributes to muscle atrophy
    • Romanello V, Guadagnin E, Gomes L, et al: Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 2010;29:1774-1785
    • (2010) EMBO J , vol.29 , pp. 1774-1785
    • Romanello, V.1    Guadagnin, E.2    Gomes, L.3
  • 50
    • 33646539841 scopus 로고    scopus 로고
    • Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats
    • Hussain SN, Matar G, Barreiro E, et al: Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats. Am J Physiol Lung Cell Mol Physiol 2006;290:L996-1003
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , pp. L996-L1003
    • Hussain, S.N.1    Matar, G.2    Barreiro, E.3
  • 52
    • 60849139422 scopus 로고    scopus 로고
    • Calpain-1 is required for hydrogen peroxide-induced myotube atrophy
    • McClung JM, Judge AR, Talbert EE, et al: Calpain-1 is required for hydrogen peroxide-induced myotube atrophy. Am J Physiol Cell Physiol 2009;296:C363-C371
    • (2009) Am J Physiol Cell Physiol , vol.296 , pp. C363-C371
    • McClung, J.M.1    Judge, A.R.2    Talbert, E.E.3
  • 53
    • 67650243261 scopus 로고    scopus 로고
    • Parkin-induced mitophagy in the pathogenesis of Parkinson disease
    • Narendra D, Tanaka A, Suen DF, et al: Parkin-induced mitophagy in the pathogenesis of Parkinson disease. Autophagy 2009;5:706-708
    • (2009) Autophagy , vol.5 , pp. 706-708
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3
  • 54
    • 0032839677 scopus 로고    scopus 로고
    • Apocynin improves diaphragmatic function after endotoxin administration
    • Supinski G, Stofan D, Nethery D, et al: Apocynin improves diaphragmatic function after endotoxin administration. J Appl Physiol (1985) 1999;87:776-782
    • (1999) J Appl Physiol (1985) , vol.87 , pp. 776-782
    • Supinski, G.1    Stofan, D.2    Nethery, D.3
  • 55
    • 0027331622 scopus 로고
    • Effect of free radical scavengers on endotoxin-induced respiratory muscle dysfunction
    • Supinski G, Nethery D, DiMarco A: Effect of free radical scavengers on endotoxin-induced respiratory muscle dysfunction. Am Rev Respir Dis 1993;148:1318-1324
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1318-1324
    • Supinski, G.1    Nethery, D.2    DiMarco, A.3
  • 56
    • 0026871147 scopus 로고
    • Effect of PEG-superoxide dismutase on the diaphragmatic response to endotoxin
    • Shindoh C, Dimarco A, Nethery D, et al: Effect of PEG-superoxide dismutase on the diaphragmatic response to endotoxin. Am Rev Respir Dis 1992;145:1350-1354
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1350-1354
    • Shindoh, C.1    Dimarco, A.2    Nethery, D.3
  • 57
    • 79959658016 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness
    • Powers SK, Hudson MB, Nelson WB, et al: Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness. Crit Care Med 2011;39:1749-1759
    • (2011) Crit Care Med , vol.39 , pp. 1749-1759
    • Powers, S.K.1    Hudson, M.B.2    Nelson, W.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.