IL-1α reversibly inhibits skeletal muscle ryanodine receptor a novel mechanism for critical illness myopathy?

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 6, 2014, Pages 1096-1106

  Friedrich, Oliver ^a,b,c   Yi, Bing ^b   Edwards, Joshua N ^c   Reischl, Barbara ^a   Wirth Huc̈king, Anette ^a   Buttgereit, Andreas ^a   Lang, Roland ^a   Weber, Cornelia ^b   Polyak, Fabian ^b   Liu, Ilon ^b   Von Wegner, Frederic ^d   Cully, Tanya R ^c   Lee, Aven ^c   Most, Patrick ^e   Vol̈kers, Mirko ^e  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d GOETHE UNIVERSITY   (Germany)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Critical illness myopathy; Cytokines; IL 1; Ryanodine receptor 1

Indexed keywords

CAFFEINE; CALCIUM ION; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; MAGNESIUM ION; RYANODINE RECEPTOR 1; TETRACAINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CHROMATIN IMMUNOPRECIPITATION; CONFOCAL MICROSCOPY; CRITICAL ILLNESS; FLUORESCENCE MICROSCOPY; FORCE TRANSDUCER; IMMUNOHISTOCHEMISTRY; MOUSE; MUSCLE CELL; MUSCLE FUNCTION; MUSCLE WEAKNESS; MYOPATHY; NONHUMAN; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; WESTERN BLOTTING;

ANIMALS; CALCIUM; CELL MEMBRANE; CRITICAL ILLNESS; INTERLEUKIN-1; MAGNESIUM; MICE; MICE, INBRED C57BL; MUSCLE FIBERS, SKELETAL; MUSCLE WEAKNESS; MUSCULAR DISEASES; PROTEIN BINDING; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 84901807432     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0059OC     Document Type: Article

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