메뉴 건너뛰기




Volumn , Issue , 2005, Pages 73-105

The biophore concept

Author keywords

ADME prediction; Biophore concept; Diversity analysis; Drug design; Library design; Pharmacophore detection; Pharmacophore fingerprint; Pharmacophore searching; Pharmacophoric groups

Indexed keywords

HUMAN COMPUTER INTERACTION;

EID: 85052951257     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/3527601813.ch4     Document Type: Chapter
Times cited : (5)

References (178)
  • 7
    • 0002117421 scopus 로고    scopus 로고
    • Evolution of the Pharmacophore Concept in Pharmaceutical Research
    • Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • P. Gund, Evolution of the Pharmacophore Concept in Pharmaceutical Research. In Pharmacophore Perception, Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA, 2000, 5-11.
    • (2000) Pharmacophore Perception , pp. 5-11
    • Gund, P.1
  • 12
    • 85080439752 scopus 로고    scopus 로고
    • 9685 Scranton Road, San Diego, CA 92121, USA
    • Catalyst. Distributed by Accelrys Inc. 9685 Scranton Road, San Diego, CA 92121, USA.
    • Distributed by Accelrys Inc
  • 14
    • 85080412420 scopus 로고
    • South Hanley Rd., St. Louis, Missouri, USA
    • UNITY® 4.2.1 Tripos, Inc., 1699 South Hanley Rd., St. Louis, Missouri, 63144, USA.
    • (1699) , pp. 63144
  • 30
    • 0013122190 scopus 로고    scopus 로고
    • Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • Y. C. Martin, in Pharmacophore Perception, Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA. 2000, 49-68.
    • (2000) Pharmacophore Perception , pp. 49-68
    • Martin, Y.C.1
  • 31
    • 0013169898 scopus 로고    scopus 로고
    • Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • G. Jones and P. Willett, In Pharmacophore Perception, Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA. 2000, 85-106.
    • (2000) Pharmacophore Perception , pp. 85-106
    • Jones, G.1    Willett, P.2
  • 33
    • 85080391452 scopus 로고    scopus 로고
    • unpublished results, Presented at the UK QSAR & Cheminformatics Group Meeting, Horsham, October
    • S.D. Pickett, J. King-Underwood, I. Wall, B. S. Sherborne unpublished results. Presented at the UK QSAR & Cheminformatics Group Meeting, Horsham, October 2001. http://www.iainm. demon.co.uk/ukqsar_autumn2001.html.
    • (2001)
    • Pickett, S.D.1    King-Underwood, J.2    Wall, I.3    Sherborne, B.S.4
  • 34
    • 0002763063 scopus 로고    scopus 로고
    • Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • O.F. Guner and D. R. Henry, in Pharmacophore Perception, Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA. 2000, 193-212.
    • (2000) Pharmacophore Perception , pp. 193-212
    • Guner, O.F.1    Henry, D.R.2
  • 42
    • 85080349499 scopus 로고    scopus 로고
    • GRID 20 is available from
    • GRID 20 is available from Molecular Discovery Ltd. http://www.moldiscovery. com/index.html.
  • 47
    • 0000392780 scopus 로고    scopus 로고
    • Development and Use in Drug Design, O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • R. D. Clark, J.M. Leonard and A. Strizhev, in Pharmacophore Perception, Development and Use in Drug Design, O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA. 2000, 151-169.
    • (2000) Pharmacophore Perception , pp. 151-169
    • Clark, R.D.1    Leonard, J.M.2    Strizhev, A.3
  • 50
    • 0343002424 scopus 로고
    • Advanced Computer-Assisted Techniques in Drug Discovery
    • G. Cruciani and S. Clementi, Methods Princ. Med. Chem. 3 (Advanced Computer-Assisted Techniques in Drug Discovery), 1995, 61-88.
    • (1995) Methods Princ. Med. Chem , vol.3 , pp. 61-88
    • Cruciani, G.1    Clementi, S.2
  • 51
    • 85080365614 scopus 로고    scopus 로고
    • developed and distributed by Tripos Inc
    • Sybyl, developed and distributed by Tripos Inc.
  • 54
    • 85080343078 scopus 로고    scopus 로고
    • is available from Multivariate Infometric Analysis S.r.l
    • ALMOND is available from Multivariate Infometric Analysis S.r.l. http://www.miasrl.com.
  • 57
    • 0001202274 scopus 로고    scopus 로고
    • 9/10/11 (3D QSAR in Drug Design: Ligand/Protein Interactions and Molecular Similarity)
    • A. C. Good and W. G. Richards, Perspect. Drug Discovery Des. 9/10/11 (3D QSAR in Drug Design: Ligand/Protein Interactions and Molecular Similarity), 1998, 321-338.
    • (1998) Perspect. Drug Discovery Des , pp. 321-338
    • Good, A.C.1    Richards, W.G.2
  • 58
    • 85080386906 scopus 로고    scopus 로고
    • ASP is a part of the TSAR3D package distributed by Acclerys Inc. http://www.accelrys.com.
  • 77
    • 85080354096 scopus 로고    scopus 로고
    • now part of Accelrys Inc
    • Chem-X was formally developed at Chemical Design (now part of Accelrys Inc.).
  • 94
    • 85080450945 scopus 로고    scopus 로고
    • San Leandro, CA, USA
    • ISIS-3D developed and distributed by MDL Information Systems Inc., San Leandro, CA, USA.
  • 104
    • 0003039809 scopus 로고    scopus 로고
    • Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA
    • O.F. Guner, M. Waldman, R. Hoffmann and J.-H. Kim, in Pharmacophore Perception, Development and Use in Drug Design O. Guner Ed. International University Line, La Jolla CA 92038-2525 USA. 2000, 213-236.
    • (2000) Pharmacophore Perception , pp. 213-236
    • Guner, O.F.1    Waldman, M.2    Hoffmann, R.3    Kim, J.-H.4
  • 105
    • 85083947176 scopus 로고    scopus 로고
    • Book of Abstracts, 214th ACS National Meeting, Las Vegas, NV, 7-11 September
    • T. Hurst. Partial-match 3D searching. Book of Abstracts, 214th ACS National Meeting, Las Vegas, NV, 7-11 September 1997 COMP-037.
    • (1997) Partial-match 3D searching , pp. COMP-037
    • Hurst, T.1
  • 106
    • 85080318690 scopus 로고    scopus 로고
    • 27401 Los Altos, Suite 370, Mission Viejo, Santa Fe, NM, USA
    • Daylight Chemical Information Systems Inc., 27401 Los Altos, Suite 370, Mission Viejo, Santa Fe, NM, USA. http://www.daylight.com.
  • 107
    • 85080373871 scopus 로고    scopus 로고
    • 14600 Catalina St., San Leandro, CA 94577
    • SSKEYS Gateway, MDL Information Systems Inc., 14600 Catalina St., San Leandro, CA 94577 http:// www.mdli.com/.
  • 125
    • 0001680792 scopus 로고    scopus 로고
    • P. v. R. Schleyer, N.L. Allinger, T. Clark, J. Gasteiger, P.A. Kollman, H.F. Schaefer III, P. R. Schreiner eds., John Wiley & Sons: Chichester
    • D.K. Agrafiotis, in The Encyclopedia of Computational Chemistry, P. v. R. Schleyer, N.L. Allinger, T. Clark, J. Gasteiger, P.A. Kollman, H.F. Schaefer III, P. R. Schreiner eds., John Wiley & Sons: Chichester, Vol. 1, 1998, 742-761.
    • (1998) The Encyclopedia of Computational Chemistry , vol.1 , pp. 742-761
    • Agrafiotis, D.K.1
  • 126
    • 85080410961 scopus 로고    scopus 로고
    • Drug Design, Kluwer Academic Publishers, Dordrecht, Netherlands
    • R. A. Lewis and P.M. Dean eds. Molecular Diversity in Drug Design, Kluwer Academic Publishers, Dordrecht, Netherlands, 1999.
    • (1999) Molecular Diversity
    • Lewis, R.A.1    Dean, P.M.2
  • 127
    • 0034355922 scopus 로고    scopus 로고
    • K. B. Lipkowitz and D.B. Boyd eds, Wiley-VCH, John Wiley & Sons Inc., New York
    • R. A. Lewis, S. D. Pickett and D. E. Clark, in Reviews in Computational Chemistry, K. B. Lipkowitz and D.B. Boyd eds., Vol. 16, Wiley-VCH, John Wiley & Sons Inc., New York, 2000, 1-51.
    • (2000) Reviews in Computational Chemistry , vol.16 , pp. 1-51
    • Lewis, R.A.1    Pickett, S.D.2    Clark, D.E.3
  • 136
    • 85080403825 scopus 로고    scopus 로고
    • 14600 Catalina St., San Leandro, CA 94577
    • MDL Information Systems, Inc. 14600 Catalina St., San Leandro, CA 94577. http://www.mdli.com.
  • 146
  • 178
    • 85080430838 scopus 로고    scopus 로고
    • R. E. Watkins et al., Science 2001, 292, 2392-2333.
    • (2001) Science , vol.292 , pp. 2333-2392
    • Watkins, R.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.