Novel Software Tools for Chemical Diversity

Perspectives in Drug Discovery and Design

Volumn 9, Issue , 1998, Pages 339-353

  Pearlman, Robert S ^a   Smith, K M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 1542633999     PISSN: 09282866     EISSN: None     Source Type: Journal    
DOI: 10.1007/0-306-46857-3_18     Document Type: Article

References (24)

1. MACSS and Isis are distributed by Molecular Design Ltd. Information Systems, San Leandro, CA.
2. Unity is distributed by Tripos, Inc., St. Louis, MO.
3. DayMenus is distributed by Daylight Chemical Information Systems, Inc., Irvine, CA.
4. ChemDBS-3D is distributed by Chemical Design Ltd., Oxford, UK.
5. Brown, R.D. and Martin, Y.C., Use of structure-activity data to compare structure-based clustering methods and descriptors for use in compound selection, J. Chem. Inf. Comp. Sci., 36 (1996), 572-584.
6. Pearlman, R.S., Novel software tools for addressing chemical diversity, NetSci, http://www.awod.com/netsci, 2 (1996), 1.
7. Pearlman, R.S., DiverseSolutions User's Manual, University of Texas, Austin, TX, 1996.
8. Burden, F.R., Molecular identification number for substructure searches, J. Chem. Inf. Comp. Sci., 29 (1989), 225-7.
9. Rusinko III, A. and Lipkus, A.M., unpublished reseults obtained at Chemical Abstracts Service,Columbus OH.
10. Pearlman, R.S. and Smith, K.M., manuscript in preparation.
11. CONCORD was developed by R.S. Pearlman, A. Rusinko, J.M. Skell, adn R. Balducci at the University of Texas, Austin TX and is distributed by Tripos, Inc., St. Louis, MO.
12. DiverseSolutions was developed by R.S. Pearlman and K.M. Smith at the University of Texas, Austin TX and is distributed by Tripos, Inc., St. Louis, MO.
13. Weintraub, H.J.R. and Demeter, D.A., personal communication.
14. Pearlman, R.S. and Deanda, F., manuscript in preparation.
15. Modern Drug Data Report distributed by Molecular Design Ltd. Information Systems, San Leandro, CA.
16. Sweet, C.S., Ulm, E.H., Gross, D.M., Vassil, T.C. and Stone, C.A., A new class of angiotensin-converting enzyme inhibitors, Nature, 288 (1980) 280-283.
17. Suh, J.T., Skiles, J.W., Williams, B.E., Youssefyeh, R.D., Jones, H., Loev, B., Neiss, E.S., Schwab, A., Mann, W.S., Khandwala, A., Wolf, P.S., and Weinryb, I., Angiotensin-Converting Enzyme inhibitors. New Orally active antihypertensive (Mercaptoalkanoyl)-and [(Acylthio)alkanoyl]glycine derivatives, J. Med. Chem., 28 (1985) 57-66.
18. Menard, P.R., Suh, J.T., Jones, H., Loev, B., Neiss, E.S., Wilde, J., Schwab, A., and Mann, W.S., Angiotensin-Converting Enzyme Inhibitors. (Mercaptoaroyl)amino acids, J. Med. Chem., 28 (1985) 328-332.
19. Wyvratt, M.J. and Patchett, A.A., Recent developments in the design of angiotensin-converting enzyme inhibitors, Med. Res. Rev., 5 (1985) 483-531.
20. Karanewsky, D.S., Badia, M.C., Cushman, D.W., DeForrest, J.M., Dejneka, T., Loots, M.J., Perri, M.G., Petrillo, E. W., and Powell, J.R., (Phosphinyloxy)acyl amino acid inhibitors of angiotensin-converting enzyme (ACE). 1. Discovery of(S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl-L-proline novel orally active inhibitor of ACE, J. Med. Chem., 31 (1988) 204-212.
21. Yanagisawa, H., Ishihara, S., Ando, A., Kanazaki, T., Miyamoto, S., Koike, H., Iijima, Y., Oizumi, K., Matsushita, Y. and Hata, T., Angiotensin-Converting Enzyme Inhibitors. 2. Perhydroazepin-2-one derivatives. J. Med. Chem., 31 (1988) 422-428.
22. Krapcho, J., Turk. C., Cushman, D.W., Powell, J.R., DeForrest, J.M., Spitzmiller, E.R., Karanewsky, D.S., Duggan, M., Rovnyak, G., Schwwartz, J., Natarajan, S., Godfrey, J.D., Ryono, D.E., Neubeck, R., Atwal, K.S., and Petrillo, E.W., Angiotensin-Converting Enzyme Inhibitors. Mercaptan, carboxyalkyl dipeptide, andphosphinic acid inhibitors incorporating 4-substituted prolines, J. Med. Chem., 31 (1988) 1148-1160.
23. Karanewsky, D.S., Badia, M.C., Cushman, D.W., DeForrest, J.M., Dejneka, T., Lee, V.G., Loots, M.J., and Petrillo, E. W., (Phosphinyloxy)acyl amino acid inhibitors of angiotensin-converting enzyme. 2. Terminal amino acid analogues of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl) phosphinyl]oxy]-1-oxohexyl]-L-proline, J. Med. Chem., 33 (1990) 1459-1469.
24. CombinDBMaker was developed by R.S. Pearlman and E.L. Stewart at the University of Texas, Austin TX and is available from the authors.